The Middle Jurassic palynomorphs from the Yan'an Formation in Dongsheng region of Nei Monggol, consist of 63 species of fossil spores and pollen grains belonging to 34 genera, of which two species were described a...The Middle Jurassic palynomorphs from the Yan'an Formation in Dongsheng region of Nei Monggol, consist of 63 species of fossil spores and pollen grains belonging to 34 genera, of which two species were described as new. Based on statistical analysis of 3 863 specimens identified in 10 samples from Hantaichuan, Nianpanlianggou and Liugou sections, the sporo-pollen assemblage from the Yan'an Formation in Dongsheng region was established, which is generally characterized by the slight dominance of gymnospermous pollen grains (generally attaining proportion of 51%-54%), whereas the pteridophytic spores reach 46%-49% in abundance. In comparison with those of adjacent regions as well as Eurasia and North America, the present sporo-pollen assemblage is regarded to early Middle Jurassic (corresponding to Bajocian Stage) in geological age. According to the climatic conditions reflected by the palynoflora, the paleoclimate in Dongsheng region is suggested to be warm temperate or subtropical warm and humid during the early Middle Jurassic.展开更多
AIM: To investigate the prevalence of vacuolating cytotoxin (vacA), cytotoxin associated gene A (cagA) and blood adhesion binding antigen (babA2) genotypes of Helicobacter pylori (H pylori) isolates from Cuba...AIM: To investigate the prevalence of vacuolating cytotoxin (vacA), cytotoxin associated gene A (cagA) and blood adhesion binding antigen (babA2) genotypes of Helicobacter pylori (H pylori) isolates from Cuban dyspeptic patients. METHODS: DNA was extracted from Hpylori-positive cultures taken from 130 dyspeptic patients. Genotyping was performed by PCR, using specific primers for vacA (s1, s2, m1, m2), cagA and babA2 genes. Endoscopic observations and histological examinations were used to determine patient pathologies. RESULTS: vacA alleles s1, s2, m1 and m2 were detected in 96 (73.8%), 34 (26.2%), 75 (57.7%) and 52 isolates (40%), respectively, while the cagA gene was detected in 95 isolates (73.2%). One hundred and seven isolates (82.3%) were babA2-positive. A significant correlation was observed between vacAs1m1 and cagA and between vacAs1ml and babA2 genotypes (P 〈 0.001 and P 〈 0.05, respectively) and between babA2 genotype and cagA status (P 〈 0.05); but, no correlation was observed between vacAsl and babA2 genotypes. Eighty five (65.4%) and 73 (56.2%) strains were type 1 (vacAsl-cagA-positive) and "triplepositive" (vacAs1-cagA-babA2-positive), respectively, and their presence was significantly associated with duodenal ulcer (P 〈 0.01 and P 〈 0.001, respectively). CONCLUSION: The distribution of the main virulence factors in the Cuban strains in this study resembled that of the Western-type strains, and the more virulent H pylori isolates were significantly associated with duodenal ulcer, ulcer disease being the worst pathology observed in the group studied.展开更多
Recent geological and paleontological exploration in the Indus basin of Pakistan allowed the discoveries of numerous remains of non-marine reptiles( titanosaurian sauropod,abelisaurian and noasaurian theropod dinosaur...Recent geological and paleontological exploration in the Indus basin of Pakistan allowed the discoveries of numerous remains of non-marine reptiles( titanosaurian sauropod,abelisaurian and noasaurian theropod dinosaurs),and marine reptiles( crocodiles),flying reptiles( pterosaurs),marine and non-marine mammals,fishes,invertebrates,and plants,especially Pakistan is relatively rich in footprints / trackways in the Mesozoic.These vertebrates of Indo-Pakistan are very significant for paleobiogeographic study due to the present-day connection of this continent with Asia in Northern Hemisphere,whereas during past( Jurassic and pre-Jurassic) it was connected to the Gondwana. The Mesozoic vertebrates show close affinities with Gondwanan landmasses.The Cenozoic vertebrates show Eurasian affinity and migrated from Indo-Pak subcontinent to Eurasia or vice versa via Paleo Indus River systems along Western Indus Suture,after long journey of about 6 000 km the first collision of Indo-Pak subcontinent with Asia occurred at terminal Cretaceous.展开更多
Every developing country has to meet the challenge of overcoming a condition of subalterrnity. After the victory of the Revolution in 1959, Cuba tackled this challenge in a very original way, prioritizing the developm...Every developing country has to meet the challenge of overcoming a condition of subalterrnity. After the victory of the Revolution in 1959, Cuba tackled this challenge in a very original way, prioritizing the development of scientific and technical know-how and of an advanced scientific system. Moreover, it pursued this goal with an extremely open attitude, using characteristic Cuban resourcefulness while at the same time taking advantage of every possible support and collaboration. While the country was increasingly integrated into the Soviet system and the Council for Mutual Economic Assistance (COMECON), and therefore benefited from a close collaboration with the Soviet Union and the Eastern European countries' higher education and scientific systems, nevertheless it constantly sought collaboration with scientists and institutions in other countries as well, in particular in the Western world. The most meaningful instance of this collaboration is the development since the 1980s of an advanced biotechnological and biomedical system, which was created independently by the Soviet Union. Quite remarkably, when the socialist system collapsed, though Cuba faced a critical situation, the strategic choice was made not to cut support to this scientific sector, but rather to reinforce it. At present Cuba produces and exports advanced and in some cases unique vaccines and drugs, and this sector ranks as third in the country's source of current hard currency.展开更多
Classical swine fever (CSF) is a highly contagious viral disease of Suidae animals, caused by a Pestivirus from Flaviviridae family, considered one major cause of economic losses to the swine producers. The CSF erad...Classical swine fever (CSF) is a highly contagious viral disease of Suidae animals, caused by a Pestivirus from Flaviviridae family, considered one major cause of economic losses to the swine producers. The CSF eradication and control program (CSFECP) established from 1992 evolved to 2001, divide the country in CSF Free Zone, without CSF vaccination and CSF infected area. The purpose of this work was to analyze the CSFECP efficacy in all Brazilian territory from 2000 to 2011 including CSF outbreaks in infected area of North and Northeast regions. CSF epidemiological data were obtained mainly from Federal Agriculture Defense Secretary and States Official Inspection Agencies. The CSF outbreaks occurred in CSF infected area were plotted and the tendency line analyzed by quadratic trend model (Minitab). The results of Brazilian statutory for CSF point to a gradual CSF-eradication in all country since the number of Federal States including at CSF Free Zone, is increasing and reached 15 of 27 Brazilian States, in period from 2001 to 2009. In seven States of infected area, 49 CSF outbreaks occurred. The stamping out was the main sanitary measure but in two Federal States Amap~. and Rio Grande do Norte the emergency vaccination was also applied. In conclusion, the eradication of CSF of all Brazilian territory is in progress but depend on the continuity of official swine diseases surveillance jointed with a rigorous control of animal movement, serological and viral activities investigations until no more outbreaks could be cited in all country.展开更多
文摘The Middle Jurassic palynomorphs from the Yan'an Formation in Dongsheng region of Nei Monggol, consist of 63 species of fossil spores and pollen grains belonging to 34 genera, of which two species were described as new. Based on statistical analysis of 3 863 specimens identified in 10 samples from Hantaichuan, Nianpanlianggou and Liugou sections, the sporo-pollen assemblage from the Yan'an Formation in Dongsheng region was established, which is generally characterized by the slight dominance of gymnospermous pollen grains (generally attaining proportion of 51%-54%), whereas the pteridophytic spores reach 46%-49% in abundance. In comparison with those of adjacent regions as well as Eurasia and North America, the present sporo-pollen assemblage is regarded to early Middle Jurassic (corresponding to Bajocian Stage) in geological age. According to the climatic conditions reflected by the palynoflora, the paleoclimate in Dongsheng region is suggested to be warm temperate or subtropical warm and humid during the early Middle Jurassic.
基金Supported by The National Centre for Scientific Research of Cuba, No. 220207
文摘AIM: To investigate the prevalence of vacuolating cytotoxin (vacA), cytotoxin associated gene A (cagA) and blood adhesion binding antigen (babA2) genotypes of Helicobacter pylori (H pylori) isolates from Cuban dyspeptic patients. METHODS: DNA was extracted from Hpylori-positive cultures taken from 130 dyspeptic patients. Genotyping was performed by PCR, using specific primers for vacA (s1, s2, m1, m2), cagA and babA2 genes. Endoscopic observations and histological examinations were used to determine patient pathologies. RESULTS: vacA alleles s1, s2, m1 and m2 were detected in 96 (73.8%), 34 (26.2%), 75 (57.7%) and 52 isolates (40%), respectively, while the cagA gene was detected in 95 isolates (73.2%). One hundred and seven isolates (82.3%) were babA2-positive. A significant correlation was observed between vacAs1m1 and cagA and between vacAs1ml and babA2 genotypes (P 〈 0.001 and P 〈 0.05, respectively) and between babA2 genotype and cagA status (P 〈 0.05); but, no correlation was observed between vacAsl and babA2 genotypes. Eighty five (65.4%) and 73 (56.2%) strains were type 1 (vacAsl-cagA-positive) and "triplepositive" (vacAs1-cagA-babA2-positive), respectively, and their presence was significantly associated with duodenal ulcer (P 〈 0.01 and P 〈 0.001, respectively). CONCLUSION: The distribution of the main virulence factors in the Cuban strains in this study resembled that of the Western-type strains, and the more virulent H pylori isolates were significantly associated with duodenal ulcer, ulcer disease being the worst pathology observed in the group studied.
文摘Recent geological and paleontological exploration in the Indus basin of Pakistan allowed the discoveries of numerous remains of non-marine reptiles( titanosaurian sauropod,abelisaurian and noasaurian theropod dinosaurs),and marine reptiles( crocodiles),flying reptiles( pterosaurs),marine and non-marine mammals,fishes,invertebrates,and plants,especially Pakistan is relatively rich in footprints / trackways in the Mesozoic.These vertebrates of Indo-Pakistan are very significant for paleobiogeographic study due to the present-day connection of this continent with Asia in Northern Hemisphere,whereas during past( Jurassic and pre-Jurassic) it was connected to the Gondwana. The Mesozoic vertebrates show close affinities with Gondwanan landmasses.The Cenozoic vertebrates show Eurasian affinity and migrated from Indo-Pak subcontinent to Eurasia or vice versa via Paleo Indus River systems along Western Indus Suture,after long journey of about 6 000 km the first collision of Indo-Pak subcontinent with Asia occurred at terminal Cretaceous.
文摘Every developing country has to meet the challenge of overcoming a condition of subalterrnity. After the victory of the Revolution in 1959, Cuba tackled this challenge in a very original way, prioritizing the development of scientific and technical know-how and of an advanced scientific system. Moreover, it pursued this goal with an extremely open attitude, using characteristic Cuban resourcefulness while at the same time taking advantage of every possible support and collaboration. While the country was increasingly integrated into the Soviet system and the Council for Mutual Economic Assistance (COMECON), and therefore benefited from a close collaboration with the Soviet Union and the Eastern European countries' higher education and scientific systems, nevertheless it constantly sought collaboration with scientists and institutions in other countries as well, in particular in the Western world. The most meaningful instance of this collaboration is the development since the 1980s of an advanced biotechnological and biomedical system, which was created independently by the Soviet Union. Quite remarkably, when the socialist system collapsed, though Cuba faced a critical situation, the strategic choice was made not to cut support to this scientific sector, but rather to reinforce it. At present Cuba produces and exports advanced and in some cases unique vaccines and drugs, and this sector ranks as third in the country's source of current hard currency.
文摘Classical swine fever (CSF) is a highly contagious viral disease of Suidae animals, caused by a Pestivirus from Flaviviridae family, considered one major cause of economic losses to the swine producers. The CSF eradication and control program (CSFECP) established from 1992 evolved to 2001, divide the country in CSF Free Zone, without CSF vaccination and CSF infected area. The purpose of this work was to analyze the CSFECP efficacy in all Brazilian territory from 2000 to 2011 including CSF outbreaks in infected area of North and Northeast regions. CSF epidemiological data were obtained mainly from Federal Agriculture Defense Secretary and States Official Inspection Agencies. The CSF outbreaks occurred in CSF infected area were plotted and the tendency line analyzed by quadratic trend model (Minitab). The results of Brazilian statutory for CSF point to a gradual CSF-eradication in all country since the number of Federal States including at CSF Free Zone, is increasing and reached 15 of 27 Brazilian States, in period from 2001 to 2009. In seven States of infected area, 49 CSF outbreaks occurred. The stamping out was the main sanitary measure but in two Federal States Amap~. and Rio Grande do Norte the emergency vaccination was also applied. In conclusion, the eradication of CSF of all Brazilian territory is in progress but depend on the continuity of official swine diseases surveillance jointed with a rigorous control of animal movement, serological and viral activities investigations until no more outbreaks could be cited in all country.