With the launch of sacubitril/valsartan(ARNI),there are new options for the treatment of heart failure(HF).However,ARNI is currently only used in HF patients with reduced ejection fraction(HFrEF).No evidence shows tha...With the launch of sacubitril/valsartan(ARNI),there are new options for the treatment of heart failure(HF).However,ARNI is currently only used in HF patients with reduced ejection fraction(HFrEF).No evidence shows that no modern treatment can reduce mortality in HF patients with preserved ejection fraction(HFpEF).Therefore,it is urgently necessary clarify whether ARNI can be used in the treatment of HFpEF.In the present study,we summarized the research progress of ARNI in the treatment of HFpEF.展开更多
Soil moisture is the key resource constraint in arid ecosystems, and has been a focus of research on restoration. However, quantitative studies on the contribution of rainfall to deep soil rainfall infiltration are la...Soil moisture is the key resource constraint in arid ecosystems, and has been a focus of research on restoration. However, quantitative studies on the contribution of rainfall to deep soil rainfall infiltration are lacking. In this study, we used the YWB-01 Deep Soil Infiltration Water Recorder which had been invented by ourselves to measure the quantity of rain infiltration into deep soil, 150 cm below ground, in four locations in China: Mu Us Sandy Land and Ulan Buh, Tengger, and Badan Jilin deserts over a 2-year period. We found:(1) Deep soil rainfall infiltration decreased progressively from east to west and from semiarid to arid areas, with two locations completely lacking rainfall infiltration. Heavy rain was important to deep soil infiltration in shifting sandy land of arid and semiarid areas.(2) Seasonal variation of infiltration was correlated with rainfall, with a time lag that was less apparent in areas with more rainfall.(3) For single intense rainfall events, infiltration maximums occurred 40–55 h after the rainfall, during which the infiltration rates increased rapidly before reaching a peak, and then decreased slowly. Continuous infiltration could last about 150 h. Rainfall infiltration was determined by the combined action of intensity, quantity and duration. Rainfall with low intensity, long duration, and large quantity was most favorable for deep soil infiltration. Our results can be used in water resource assessments and protection during eco-restoration in the arid and semiarid areas in China.展开更多
文摘With the launch of sacubitril/valsartan(ARNI),there are new options for the treatment of heart failure(HF).However,ARNI is currently only used in HF patients with reduced ejection fraction(HFrEF).No evidence shows that no modern treatment can reduce mortality in HF patients with preserved ejection fraction(HFpEF).Therefore,it is urgently necessary clarify whether ARNI can be used in the treatment of HFpEF.In the present study,we summarized the research progress of ARNI in the treatment of HFpEF.
基金supported by the National Basic Research Program of China (Grant No. 2013CB429901)the National Natural Science Foundation of China (Grant Nos. 31170667 and 40971283)
文摘Soil moisture is the key resource constraint in arid ecosystems, and has been a focus of research on restoration. However, quantitative studies on the contribution of rainfall to deep soil rainfall infiltration are lacking. In this study, we used the YWB-01 Deep Soil Infiltration Water Recorder which had been invented by ourselves to measure the quantity of rain infiltration into deep soil, 150 cm below ground, in four locations in China: Mu Us Sandy Land and Ulan Buh, Tengger, and Badan Jilin deserts over a 2-year period. We found:(1) Deep soil rainfall infiltration decreased progressively from east to west and from semiarid to arid areas, with two locations completely lacking rainfall infiltration. Heavy rain was important to deep soil infiltration in shifting sandy land of arid and semiarid areas.(2) Seasonal variation of infiltration was correlated with rainfall, with a time lag that was less apparent in areas with more rainfall.(3) For single intense rainfall events, infiltration maximums occurred 40–55 h after the rainfall, during which the infiltration rates increased rapidly before reaching a peak, and then decreased slowly. Continuous infiltration could last about 150 h. Rainfall infiltration was determined by the combined action of intensity, quantity and duration. Rainfall with low intensity, long duration, and large quantity was most favorable for deep soil infiltration. Our results can be used in water resource assessments and protection during eco-restoration in the arid and semiarid areas in China.
