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抗震颤麻痹新药布地品对大鼠多巴胺释放的药效研究
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作者 杨正明 杨晓云 《中国新药杂志》 CAS CSCD 1999年第3期180-182,共3页
目的:研究抗震颤麻痹新药布地品(budipine)对电刺激大鼠前脑正中束(MFB)引起尾壳核(CPu)内多巴胺释放的药效,探讨布地品的作用机制。方法:24只大鼠等分3组,分别ip30mg/kg布地品以及等容量的0.... 目的:研究抗震颤麻痹新药布地品(budipine)对电刺激大鼠前脑正中束(MFB)引起尾壳核(CPu)内多巴胺释放的药效,探讨布地品的作用机制。方法:24只大鼠等分3组,分别ip30mg/kg布地品以及等容量的0.1mol/L磷酸缓冲液(为cremophor的溶剂)和10%cremophor(为布地品的溶剂)。采用快速循环伏安计测定法(FCV)测定注射药物及对照剂后电刺激MFB引起同侧CPu内多巴胺释放量的变化。结果:将每组大鼠注射药物或对照剂前电刺激FMB引起CPu内多巴胺释放的量定为100%,注射60min后,布地品组多巴胺释放量减至为(34.2±22.5)%,0.1mol/L磷酸缓冲液组减至为(69.0±18.9)%,10%cremophor组减至为(70.6±28.8)%,布地品组的多巴胺释放量较对照组明显减少。结论:布地品对电刺激大鼠MFB引起CPu内多巴胺释放有明显抑制作用。 展开更多
关键词 布地品 多巴胺释放 药效学 新药 药理
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布地品与米氮平的副作用
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作者 王孝伟 凌仰之 《国外药讯》 2000年第12期32-32,共1页
关键词 布地品 米氮平 副作用 心血管病
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新的抗帕金森病药物布地品口服给药后的剂量线形和稳态药代动力学
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作者 钟伯华 《国外医学(药学分册)》 2002年第1期60-60,共1页
关键词 抗帕金森病药物 布地品 疗效 药代动力学 给药剂量 效应-剂量关系
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Oil shale resources in China and their utilization 被引量:2
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作者 XU Zhi ZHU Jianwei +1 位作者 DONG Qingshui SUN Pingchang 《Global Geology》 2016年第1期48-54,共7页
The unconventional oil and gas resources presented in oil shales have meant these potential sources of hydrocarbons, which has become a research focus. China contains abundant oil shale resources, ranking fourth in th... The unconventional oil and gas resources presented in oil shales have meant these potential sources of hydrocarbons, which has become a research focus. China contains abundant oil shale resources, ranking fourth in the world, with ca. 7 254.48 x 108 t within 24 provinces, including 48 basins and 81 oil shale deposits. A- bout 48% of the total oil shale resources are concentrated in the eastern resource region, with a further 22% in the central resource region. 65 % of the total quantity of oil shale resources is present at depths of 0-500 m, with 17% of the total resources being defined as high-quality oil shales yielding more than 10% oil by weight. Chinese oil shale resources are generally hosted by Mesozoic sediments that account for 78% of the total re- sources. In terms of the geographical distribution of these resources, some 45% are located in plain regions, and different oil shale basins have various characteristics. The oil shale resources in China represent a highly prospective future source of hydrocarbons. These resources having potential use not only in power generation and oil refining but also in agriculture, metal and chemical productions, and environmental protection. 展开更多
关键词 China oil shale RESOURCES DISTRIBUTION UTILIZATION
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Role of Buffalo in International Trade
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作者 I. Soliman H. Bassiony 《Journal of Agricultural Science and Technology(B)》 2011年第6期799-809,共11页
The study analyzed the foreign trade performance of buffalo products using several indicators. These are the foreign trade structure by product and by Geographic distribution, time trend, instability, the free on boar... The study analyzed the foreign trade performance of buffalo products using several indicators. These are the foreign trade structure by product and by Geographic distribution, time trend, instability, the free on board or freight on board (FOB) price ratio of buffalo to cattle revealed comparative advantage of tradable buffalo products. Thailand has the highest buffalo exports of live animals and hides. India exports the highest share of buffalo meat. Buffalo dairy products exports are rare due to lack of expanded dairy processing industries of buffalo milk and lacking of awareness towards the buffalo milk quality, which limits the demand for buffalo dairy products and shortage in supply beyond the domestic consumption. While buffalo stock all over the world represents 12% of the world bovine stock, its share in buffalo exports of meat is around 27% of the world bovine exports measured in tons in 2007. Such share shrinkages to 13.2% when measured in dollars. This shrinkage is due to lower prices of buffalo products than cattle products. The ratio of annual average "FOB price" of buffalo meat to bovine price was about one-half and for hides was about 40%, and for live buffalo was 14%. Reasons of the apparent lower FOB price of buffalo Exported Products than cattle are the low carcass weight of buffalo exported mainly for processing, low quality and limited demand for buffalo hides, and commonly, exporting live buffalo as weaned calves. Expansion in exports of buffalo products requires expansion in supply, through the potentiality of higher productivity, rather than stock size, to reach in balance with available feeds. 展开更多
关键词 Buffalo productivity trend instability of foreign trade revealed comparative advantage.
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