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双树 我的故乡我的树
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作者 隋守兰 《中国土族》 2012年第4期57-58,共2页
无论经历怎样的风雨沧桑,从两棵大树下走出的双树人,不论走多远,身在何处,都会回来看看村头那两棵粗砺苍劲的古树。春暖花开的季节,华盖如阴、枝叶浓密的树,宜于思慕、祈祷、重逢,它的姿态是繁重的、厚重的、持久的。青海省互助土族自... 无论经历怎样的风雨沧桑,从两棵大树下走出的双树人,不论走多远,身在何处,都会回来看看村头那两棵粗砺苍劲的古树。春暖花开的季节,华盖如阴、枝叶浓密的树,宜于思慕、祈祷、重逢,它的姿态是繁重的、厚重的、持久的。青海省互助土族自治县塘川镇双树村,一片红色的土地。 展开更多
关键词 故乡 苦苦菜 双树 父母亲 妈妈 念想 酸菜 蕨麻 布证
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CFD Simulation and Experimental Validation of Fluid Flow in Pre-distributor 被引量:6
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作者 张吕鸿 高国华 +2 位作者 隋红 李洪 李鑫钢 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2011年第5期815-820,共6页
Liquid distributor is a very import intemal for distillation columns. Pre-distributor is usually set on the top of distributor for initial distribution. Fluid flow in pre-distributor is a complex system of variable ma... Liquid distributor is a very import intemal for distillation columns. Pre-distributor is usually set on the top of distributor for initial distribution. Fluid flow in pre-distributor is a complex system of variable mass flow with many orifices and sub-branches. Consequently, the two phase modeling of pre-distributors was carried out andthe homogeneous model with free surface model was applied. The numerical method was validated by comparing with experimental data. Using the simulated results for different pre-distributors, the impacts of inflow rate, location and orientation uoon the outflow distribution were investigated. Furthermore, influences of the outflow distribution for pre-distributor on liquid uniformity in trough were also analyzed, The conclusions can De aaoptea for me structural design of liquid distributor and pre-distributor of large scale. 展开更多
关键词 pre-distributor computational fluid dynamics ORIFICES TROUGH outflow distribution
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Privacy-preserving Distributed Location Proof Generating System 被引量:3
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作者 LIU Mengjun LIU Shubo +3 位作者 ZHANG Rui Li Yongkai WANG Jun CAO Hui 《China Communications》 SCIE CSCD 2016年第3期203-218,共16页
The rapid development of location-based service(LBS) drives one special kind of LBS, in which the service provider verifies user location before providing services. In distributed location proof generating schemes, pr... The rapid development of location-based service(LBS) drives one special kind of LBS, in which the service provider verifies user location before providing services. In distributed location proof generating schemes, preventing users from colluding with each other to create fake location proofs and protecting user's location privacy at the same time, are the main technical challenges to bring this kind of LBS into practical. Existing solutions tackle these challenges with low collusion-detecting efficiency and defected collusion-detecting method. We proposed two novel location proof generating schemes, which inversely utilized a secure secret-sharing scheme and a pseudonym scheme to settle these shortcomings. Our proposed solution resists and detects user collusion attacks in a more efficient and correct way. Meanwhile, we achieve a higher level of location privacy than that of previous work. The correctness and efficiency of our proposed solution is testified by intensive security analysis, performance analysis, as well as experiments and simulation results. 展开更多
关键词 computer software and theory location proof secret-sharing location privacy
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Accounting variables and stock returns: Evidence from Istanbul stock exchange
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作者 Beng Vuran Burcu Adiloglu 《Journal of Modern Accounting and Auditing》 2010年第8期38-46,共9页
The fundamental relationship between accounting variables and stock returns is a recurring theme in financial research. One of the major purposes of accounting is to help investors provide reliable, comparable and acc... The fundamental relationship between accounting variables and stock returns is a recurring theme in financial research. One of the major purposes of accounting is to help investors provide reliable, comparable and accurate information. If accounting data are informative about fundamental values and changes in values, they should be correlated with stock price changes. This study provides theory and evidence showing how accounting variables explain stock returns and examines the relationship between the stock returns and accounting variables of listed non financial companies in ISE-100 Indice for 2006-2008 period by using panel data methodology. Empirical analysis consists of 192 observations of 64 companies in years 2006-2008 to examine the effects of inventory, accounts receivable, gross margin, operating expense, return on assets, cash flow, leverage, liquidity, price/earnings, return on equity on stock returns. The results of the study confirm that the predicted roles of fundamental factors and stock returns are significantly related to gross margin, cash flow, leverage and equity variables. The model explains about 13.35 % of the variation of annual stock returns with the leverage variable with most of the significant power. 展开更多
关键词 stock returns accounting variables panel data methodology
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Moments and limiting distribution of a portfolio of whole life annuity policies 被引量:1
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作者 何文炯 张奕 《Journal of Zhejiang University Science》 CSCD 2002年第4期449-454,共6页
A dual random model of a portfolio of variable amount whole life annuity is set with the mth moment of the present value of benefits, and the respective expressions of the moments under the assumption that the force o... A dual random model of a portfolio of variable amount whole life annuity is set with the mth moment of the present value of benefits, and the respective expressions of the moments under the assumption that the force of interest accumulation function is Wiener process or Ornstein-Uhlenbeck process. Furthermore, the limiting distribution of average cost of this portfolio is discussed with the expression of the limiting distribution under the assumption that the force of interest accumulation is an independent increment process. 展开更多
关键词 Whole life annuity policy Force of interest Present value of benefit Moment Limiting distribution Wiener process Ornstein-Uhlenbeck process Independent increment process
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Application of evidence theory in information fusion of multiple sources in bayesian analysis 被引量:4
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作者 周忠宝 蒋平 武小悦 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2004年第4期461-463,共3页
How to obtain proper prior distribution is one of the most critical problems in Bayesian analysis. In many practical cases, the prior information often comes from different sources, and the prior distribution form cou... How to obtain proper prior distribution is one of the most critical problems in Bayesian analysis. In many practical cases, the prior information often comes from different sources, and the prior distribution form could be easily known in some certain way while the parameters are hard to determine. In this paper, based on the evidence theory, a new method is presented to fuse the information of multiple sources and determine the parameters of the prior distribution when the form is known. By taking the prior distributions which result from the information of multiple sources and converting them into corresponding mass functions which can be combined by Dempster-Shafer (D-S) method, we get the combined mass function and the representative points of the prior distribution. These points are used to fit with the given distribution form to determine the parameters of the prior distribution. And then the fused prior distribution is obtained and Bayesian analysis can be performed. How to convert the prior distributions into mass functions properly and get the representative points of the fused prior distribution is the central question we address in this paper. The simulation example shows that the proposed method is effective. 展开更多
关键词 Bayesian analysis evidence theory D-S method information fusion
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Research on E-mail Communication Network Evolution Model Based on User Information Propagation 被引量:1
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作者 ZHANG Lejun GUO Lin XU Li 《China Communications》 SCIE CSCD 2015年第7期108-118,共11页
E-mail communication network evolution model based on user information propagation is studied. First, mathematical representation of weighted e-mail communication network is proposed, and network center parameters of ... E-mail communication network evolution model based on user information propagation is studied. First, mathematical representation of weighted e-mail communication network is proposed, and network center parameters of Enron dataset and the distribution of node degree and strength are analyzed. Then, some rules of e-mail communication network evolution are found. Second, the model of e-mail information propagation is described, and e-mail communication network evolution model based on user information propagation is proposed. Lastly, the simulation proves the correctness of the distribution characteristic of degree and strength of the model proposed and then verifies that the model proposed is closer to the real situation of e-mail communication network through parameter comparison. This research provides the basis for other researches on social network evolution and data communication. 展开更多
关键词 E-MAIL social network analysis network evolution information propagation
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Validating Wind Energy Probability at Ahmednagar Wind Farm
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作者 M.M. Hapse A.G. Thosar S.M. Shinde 《Journal of Energy and Power Engineering》 2011年第2期189-194,共6页
The wind speed is measured with the help of three anemometers S30, S45, S60 placed at 30 m, 45 m, and 60 m height. Mean values are recorded and stored for every hour using a data logger. For accounting wind turbine ge... The wind speed is measured with the help of three anemometers S30, S45, S60 placed at 30 m, 45 m, and 60 m height. Mean values are recorded and stored for every hour using a data logger. For accounting wind turbine generator (WTG.) tower height, data recorded from S60 anemometer at 60 m height is used for analysis purpose. This paper analyzes the probability distribution of wind speed data recorded by maharashtra energy development agency (MEDA) wind farm at Ahmednagar (India). The main objective is to validate the wind energy probability by using probability distribution function (PDF) of available wind potential. The energy generated from wind for any time interval is equal to the area tinder power curve multiplied by time in hours for that time interval. To estimate the wind energy probability, hourly wind speed data tbr one year interval is selected. Weibull distribution is adopted in this study to best fit the wind speed data. The scale and shape paranleters are estimated by using maximum likelihood method. The goodness of fit tests based on the probability density function (PDF) is conducted to show that the distribution adequately fits the data. It is found from the curve fitting test that, although the two distributions are all suitable for describing the probability distribution of wind speed data, the two-parameter weibull distribution is more appropriate than the lognormal distribution. 展开更多
关键词 Probability distribution ftmction wind farm energy generation weibull LOGNORMAL
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A New Approach to Predict Financial Failure: Classification and Regression Trees (CART) 被引量:1
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作者 Ayse Guel Yllgoer UEmit Dogrul Guelhan Orekici Temel 《Journal of Modern Accounting and Auditing》 2011年第4期329-339,共11页
The increase of competition, economic recession and financial crises has increased business failure and depending on this the researchers have attempted to develop new approaches which can yield more correct and more ... The increase of competition, economic recession and financial crises has increased business failure and depending on this the researchers have attempted to develop new approaches which can yield more correct and more reliable results. The classification and regression tree (CART) is one of the new modeling techniques which is developed for this purpose. In this study, the classification and regression trees method is explained and tested the power of the financial failure prediction. CART is applied for the data of industry companies which is trade in Istanbul Stock Exchange (ISE) between 1997-2007. As a result of this study, it has been observed that, CART has a high predicting power of financial failure one, two and three years prior to failure, and profitability ratios being the most important ratios in the prediction of failure. 展开更多
关键词 business failure financial distress PREDICTION classification and regression trees (CART)
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Exploring the Retailer's Relational Satisfaction in a Non-western Context: Evidence From the Tunisian Post 2011 's RevolutionSetting
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作者 Rym BenHalima Rym Trabelsi 《Chinese Business Review》 2017年第6期278-291,共14页
The current research aims to find out whether the model of the retailer's relational satisfaction, developed in a western setting is relevant in a different economic and cultural field of investigation: the Tunisian... The current research aims to find out whether the model of the retailer's relational satisfaction, developed in a western setting is relevant in a different economic and cultural field of investigation: the Tunisian post 2011 revolution's emerging context, and in a different industry: the retail industry. It explores the distinctive economic and cultural features that affect the retailer's relational satisfaction with its consumer goods manufacturers. The study employs a survey based on a face-to-face administered questionnaire. Two hundred and thirty four responses from a survey with Tunisian retailers as well as international retailers operating in Tunisia were obtained. All constructs are measured using five-point Likert type scales (1 = strongly disagree, 5 = strongly agree). Analyses are conducted using exploratory factor analysis and reliability analysis. The results support the original model with however some differences derived from the Tunisian economic setting as a whole, the characteristics of the Tunisian consumer goods industry as well as the clan characteristic feature of the Tunisian collectivistic culture. Thus, the amount of discounts obtained, does no longer contribute to the retailer's economic satisfaction. Moreover, when it comes to social satisfaction, the respondents get uncomfortable, even to deal with a potential negative interaction with their suppliers. For retail companies involved in internationalization in the Maghreb Region, and especially in Tunisia, it seems that other competitive advantages than prices are to be developed, such as the development of private label or other services that create positive perceived value for the Tunisian customer. From a cultural standpoint, western managers have rather to go away from a formalized channel relationship management, while taking into account the importance of interpersonal influence. The study sheds light on the heterogeneity of the so-called Arab-Muslim world. This is highlighted in the management of channel relationship in Tunisia, that is influenced by: (1) The government's price regulation and control, especially in many food products; (2) The relative weak importance of discounts in gaining retailer's economic satisfaction; (3) The reshaping of the local retailing sector due to the arrival of international retail companies; (4) The clan feature of the Tunisian collectivistic culture that advocates putting priority on interpersonal influence in channel relationship's management. 展开更多
关键词 channel relationship relational satisfaction retailer's satisfaction economic satisfaction socialsatisfaction emerging economy Arab-Muslim context
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Evidence of Invariance of Time Scale at Critical Point in Ising Meanfield Equilibrium Equation of State
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作者 Muktish Acharyya Ajanta Bhowal Acharyya 《Communications in Theoretical Physics》 SCIE CAS CSCD 2011年第6期1109-1112,共4页
We solve the equilibrium meanfield equation of state of Ising ferromagnet (obtained from Bragg-Williams theory) by Newton-Raphson method. The number of iterations required to get a convergent solution (within a spe... We solve the equilibrium meanfield equation of state of Ising ferromagnet (obtained from Bragg-Williams theory) by Newton-Raphson method. The number of iterations required to get a convergent solution (within a specified accuracy) of equilibrium magnetisation, at any particular temperature, is observed to diverge in a power law fashion as the temperature approaches the critical value. This is identified as the critical slowing down. The exponent is also estimated. This value of the exponent is compared with that obtained from analytic solution. Besides this, the numerical results are also compared with some experimental results exhibiting satisfactory degree of agreement. It is observed from this study that the information of the invariance of time scale at the critical point is present in the meanfield equilibrium equation of state of Ising ferromagnet. 展开更多
关键词 Ising model meanfield theory Newton-Raphson method relaxation time critical slowing down
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Structural Stress Identification Using Fuzzy Pattern Recognition and Information Fusion Technique 被引量:1
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《Journal of Civil Engineering and Architecture》 2012年第4期479-488,共10页
In order to ensure the service security of space structures under wind load, the stress identification method based on the combination of fuzzy pattern recognition and information fusion technique is proposed, in whic... In order to ensure the service security of space structures under wind load, the stress identification method based on the combination of fuzzy pattern recognition and information fusion technique is proposed, in which the measurements of limited strain sensors arranged on the structure are used. Firstly, the structure is divided into several regions according to the similarity and the most unfavorable region is selected to be the key region for stress identification, while the different numbers of the strain sensors are located on the key region and the normal regions; secondly, the different stress distributions of the key region are obtained based on the measurements of the strain sensors located on the key region and the normal regions separately, in which the fuzzy pattern recognition is used to identify the different stress distributions; thirdly, the stress distributions obtained by the measurements of sensors in normal regions are selected to calculate the synthesized stress distribution of the key region by D-S evidence theory; fourthly, the weighted fusion algorithm is used to assign the different fusion coefficients to the selected stress distributions obtained by the measurements of the normal regions and the key region, while the synthesized stress distribution of the key region can be obtained. Numerical study on a lattice shell model is carried out to validate the reliability of the proposed stress identification method. The simulated results indicate that the method can improve identification accuracy and be effective by different noise disturbing. 展开更多
关键词 Stress identification Fuzzy pattern recognition information fusion technique
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A Textual Research on the Image of"Gaomei God" in the Stone Relief of the Han Dynasty
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作者 LU Shou-ye 《Journal of Literature and Art Studies》 2017年第12期1592-1603,共12页
As the most primitive and the highest-level media in ancient Chinese society, Gaomei God played a pivotal role in the social life of the Han Dynasty. The stone relief is a vivid portrayal of the Han Dynasty society, a... As the most primitive and the highest-level media in ancient Chinese society, Gaomei God played a pivotal role in the social life of the Han Dynasty. The stone relief is a vivid portrayal of the Han Dynasty society, and we can use the format routine method to fred out the image of Gaomei God in it. Starting from the Gaomei portrait, a research on typology is carried out before the portrait is divided into three types on the basis of its development and evolution, which is followed by a comprehensive analysis of its time, distribution area, configuration combination, carving techniques, image composition, development in a way to sum up the law of Gaomei portrait. 展开更多
关键词 Gaomei stone relief of the Han Dynasty TYPE
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Methodological Approaches to Study Internet Financial Communication
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作者 Pozniak Laetitia 《Journal of Modern Accounting and Auditing》 2015年第1期27-40,共14页
The aim of this paper is to show how qualitative and quantitative approaches can be complementary to study internet financial communication in a thesis by papers and how grounded theory (GT) can be the link among th... The aim of this paper is to show how qualitative and quantitative approaches can be complementary to study internet financial communication in a thesis by papers and how grounded theory (GT) can be the link among the different papers of the thesis. The study context of our thesis was the unregulated markets of New York Stock Exchange (NYSE) Euronext Brussels and the problematic rose from this context: What is the voluntary effort of communication when there is no obligation of internet financial communication? Four papers tried to answer this central question and other following research questions. To answer those research questions, several methodological approaches were used: content analysis of websites and scoring, linear regression, paired sample, and interviews. At the end of our thesis by papers, we discovered that GT was the general methodological travel among the papers: Every article had for vocation to try to answer the questions raised by the previous article. 展开更多
关键词 quantitative and qualitative approaches grounded theory (GT) INDUCTION financial communication INTERNET unregulated markets
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Lateral displacement of silty clay under cement-fly ash-gravel pile-supported embankments: Analytical consideration and field evidence 被引量:5
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作者 张崇磊 蒋关鲁 +1 位作者 刘先峰 王智猛 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第4期1477-1489,共13页
Based on back analysis of lateral displacements measured in situ by using the analytical solution, a useful method for estimating stress concentration ratio of geosynthetic-reinforced and pile-supported(GRPS) embankme... Based on back analysis of lateral displacements measured in situ by using the analytical solution, a useful method for estimating stress concentration ratio of geosynthetic-reinforced and pile-supported(GRPS) embankments was proposed. In order to validate the proposed method, a full-scale high-speed railway embankment(HSRE) with four instrumented subsections over medium compressibility silty clay was constructed in three stages. The soil profile, construction procedure and monitoring of settlements and lateral displacements of the four test sections were described. The field deformation analysis results show that 1) the combined reinforcement of CFG piles and geosynthetic layer perform well in terms of reducing lateral displacements; 2) the development of lateral displacements lags behind the increase of fill load, which can be attributed to the vertical load transfer mechanism of the pile foundation; and 3) pile length has a dominant effect on the stress distribution proportion between piles and surrounding soils. The comparison between predicted and experimental results suggests that the proposed analytical solution and the back analysis-based method are capable of reasonably estimating the lateral deformation and the stress concentration ratio, respectively, if the appropriate soil elastic modulus is chosen. 展开更多
关键词 piled-supported embankment silty clay lateral displacement field test stress concentration ratio
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Effectiveness of the Financial Ratios in the Determination of the Fraudulent Financial Statements" Turkey Practice
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作者 Suat Kara Ayse N. Yereli 《Journal of Modern Accounting and Auditing》 2013年第10期1342-1353,共12页
Large-scale accounting scandals which were reflected to the world public opinion particularly in the 2000s (such as Enron, Lucent, Xerox, and Parmalat Bank for Reconstruction) carried the matter of fraudulent financ... Large-scale accounting scandals which were reflected to the world public opinion particularly in the 2000s (such as Enron, Lucent, Xerox, and Parmalat Bank for Reconstruction) carried the matter of fraudulent financial reporting which was made to deceive the financial statement users (Fraudulent Financial Report (FFR)) to the forefront in the agenda of the academicians, operators, and regulatory authorities. As in every crime action, the most effective measure to be taken in preventing FFR events is to try to prevent the FFR before arising. In order to achieve this, in the most effective manner, FFR events should be determined in the formation process. In this study, fraudulent financial statements are tried to be determined by using financial ratios. For this, financial statements of 22 companies which transact in the textile industry in Istanbul Stock Exchange (ISE) were examined. Twenty-three financial ratios were selected for the purpose of determining the risk of fraudulence in the financial statements of the selected companies. These ratios increased in value by multiple regression analysis. The findings which were obtained in the study indicated that some financial statements had the risk of fraudulence. It was concluded that the ratios of inventory/current asset, total debt ratio, and equity turnover rate were a good indicator in the determination of fraudulent financial statements. 展开更多
关键词 financial fraud financial statement financial ratio
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Comparison of Efficiencies of Enterprises Engaged in Food Sector in Turkey by Data Envelopment Analysis Taking Account of Their Efficiencies and Rantability Rates
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作者 Filiz Cakir Zeytinoglu Sezayi Dumanoglu Mert Uydaci 《Journal of Modern Accounting and Auditing》 2011年第2期182-192,共11页
Enterprises are in competition with other enterprises operating in their fields. In today's world, enterprises need to increase their efficiency and productivity, the values of which, if below market conditions, they... Enterprises are in competition with other enterprises operating in their fields. In today's world, enterprises need to increase their efficiency and productivity, the values of which, if below market conditions, they need to raise. Data Envelopment Analysis, widely utilized in efficiency and productivity measurements is a method that measures the efficiency of one unit relatively, taking more than one input determines the efficiency of units with similar inputs and outputs and output simultaneously. DEA interactively Thus, not only the efficient units are determined, but an opinion is offered as to how the inefficient units can be improved. In this study, 12 enterprises that were among the first 500 enterprises in Turkey in 2008, active in Istanbul Stock Exchange and operating in food sector through Data Envelopment Analysis. In the model, activity rates were used as input values, rantability rates were used as output values. In conclusion of simultaneous analysis of input and output values, efficient and inefficient enterprises were determined. 展开更多
关键词 data envelopment analysis decision making units CCR BCC consumption cooperatives retailing
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From Sequential to Parallel Growth of Cities: Theory and Evidence from Canada
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作者 SHENG Kerong FAN Jie +1 位作者 SUN Wei MA Hailong 《Chinese Geographical Science》 SCIE CSCD 2016年第3期377-388,共12页
This paper examines city growth patterns and the corresponding city size distribution evolution over long periods of time using a simple New Economic Geography(NEG) model and urban population data from Canada. The mai... This paper examines city growth patterns and the corresponding city size distribution evolution over long periods of time using a simple New Economic Geography(NEG) model and urban population data from Canada. The main findings are twofold. First, there is a transition from sequential to parallel growth of cities over long periods of time: city growth shows a sequential mode in the stage of rapid urbanization, i.e., the cities with the best development conditions will take the lead in growth, after which the cities with higher ranks will become the fastest-growing cities; in the late stage of urbanization, city growth converges according to Gibrat′s law, and exhibits a parallel growth pattern. Second, city size distribution is found to have persistent structural characteristics: the city system is self-organized into multiple discrete size groups; city growth shows club convergence characteristics, and the cities with similar development conditions eventually converge to a similar size. The results will not only enhance our understanding of urbanization process, but will also provide a timely and clear policy reference for promoting the healthy urbanization of developing countries. 展开更多
关键词 sequential city growth Gibrta′s law finite mixture model convergence club Canada
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Electron Momentum Distributions for 4a1 Orbitals of CFxCl4-x in Low Momentum Region: a Possible Evidence of Molecular Geometry Distortion
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作者 Xu Shan Chun-kai Xu +3 位作者 Xiao-feng Yin Li-xia Zhou Ke-zun Xu Xiang-jun Chen 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2009年第6期642-648,J0002,共8页
Electron momentum distributions for 4a1 orbitals of serial freon molecules CFaC1, CF2Cl2, and CFCl3 (CFxC14-x, x=1-3) have been reanalyzed due to the severe discrepancies between theory and experiment in low momentu... Electron momentum distributions for 4a1 orbitals of serial freon molecules CFaC1, CF2Cl2, and CFCl3 (CFxC14-x, x=1-3) have been reanalyzed due to the severe discrepancies between theory and experiment in low momentum region. The tentative calculations using equilibrium geometries of molecular ions have exhibited a great improvement in agreement with the experimental data, which suggests that the molecular geometry distortion may be responsible for the observed high intensities at p〈0.5 a.u.. Further analyses show that the severe discrepancies at low momentum region mainly arise from the influence of molecular geometry distortion on C-Cl bonding electron density distributions. 展开更多
关键词 (e 2e) Electron momentum spectroscopy Molecular geometry distortion Electron density distribution
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流津润燥浓煎剂治疗原发性干燥综合征的疗效及安全性评价 被引量:21
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作者 胡伟 徐蕾 +5 位作者 徐长松 徐媚媚 郭亮 陈月月 徐大可 项承荣 《中国中西医结合杂志》 CAS CSCD 北大核心 2017年第2期179-183,共5页
目的评价流津润燥浓煎剂治疗原发性干燥综合征(primary Sjgren's syndrome,pSS)的疗效及安全性。方法将40例原发性干燥综合征津亏失布证患者按1∶1的比例随机分入试验组和对照组,两组均给予标准治疗:白芍总苷600 mg,每日2次。试... 目的评价流津润燥浓煎剂治疗原发性干燥综合征(primary Sjgren's syndrome,pSS)的疗效及安全性。方法将40例原发性干燥综合征津亏失布证患者按1∶1的比例随机分入试验组和对照组,两组均给予标准治疗:白芍总苷600 mg,每日2次。试验组在标准治疗基础上给予流津润燥浓煎剂,每次30 m L口服,每日2次。对照组只标准治疗,服药4周为1个疗程,连续观察2个疗程。综合评价两组口干眼干改善疗效;并进行Schirmer试验及唾液流率测定;观察中医证候评分,血沉、免疫球蛋白等指标及药物不良反应。结果在8周结束时口干眼干改善综合疗效试验组有效率为80%,对照组为35%,两组比较差异有统计学意义(χ~2=8.286,P<0.05)。两组口干眼干积分与治疗前比较均下降,试验组治疗8周时差值大于对照组,两组8周时差值(95%CI)为1.71分(-0.37~3.78),差异均有统计学意义(P<0.05);试验组唾液流率及Schirmer试验与治疗前比较有改善,但差异无统计学意义(P>0.05),试验组治疗8周时差值大于对照组[两组8周时差值(95%CI)分别为2.74 m L/15 min(0.49~4.98)、0.13 mm/5 min(-0.92~1.23)],差异有统计学意义(P<0.05)。两组中医证候积分与治疗前比较均下降,试验组治疗8周时差值优于对照组[两组8周时差值(95%CI)为1.71分(-1.40~4.81)],差异无统计学意义(P>0.05)。对照组有1例出现尿路感染,试验组未出现明显不良事件。结论标准治疗联合流津润燥浓煎剂对p SS津亏失布证患者的口干眼干综合疗效比单纯标准治疗更好。 展开更多
关键词 流津润燥浓煎剂 原发性干燥综合征 津亏失布证 随机对照试验
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