Anomaly Detection Method Using Feature Reconstruction Based Knowledge Distillation

In recent years,anomaly detection has attracted much attention in industrial production.As traditional anomaly detection methods usually rely on direct comparison of samples,they often ignore the intrinsic relationship between samples,resulting in poor accuracy in recognizing anomalous samples.To address this problem,a knowledge distillation anomaly detection method based on feature reconstruction was proposed in this study.Knowledge distillation was performed after inverting the structure of the teacher-student network to avoid the teacher-student network sharing the same inputs and similar structure.Representability was improved by using feature splicing to unify features at different levels,and the merged features were processed and reconstructed using an improved Transformer.The experimental results show that the proposed method achieves better performance on the MVTec dataset,verifying its effectiveness and feasibility in anomaly detection tasks.This study provides a new idea to improve the accuracy and efficiency of anomaly detection.

The Diagnosis and Treatment of Virilizing and Fem- inizing Adrenal Syndrome

Objective: To inquire into diagnosis, and treatment of virilizing andfeminizing a-drenal syndrome, differential diagnosis between benign and malignant sex hormoneproducing adrenal neo-plasma and, treatment principles of congenital adrenal hyperplasia (CAH).Methods: Eight cases of CAH and 5 cases of sex hormone producing adrenal neoplasma were admitted tohospital during 1986-1996. The former included 3 rare cases of 17 a hydroxylase deficiency. Thelatter included 3 cases of feminizing adrenal tumor and 2 cases of virilizing adrenal tumor.Results: Weight, size and CT of the tumor, DHEA, 17 -ks, sex hormone levels, infiltration, andmetastasis were closely related to the degree of differentiation of the tumors. Conclusion:Virilizing and feminizing adrenal neoplasm were removed surgically by different incisions. Modifiedsubcostal incision was recommended as the best choice for huge adrenal mass. Corticoadrenal hormonetreatment fa CAH should be individualized according to the different types of the disease. Sexhormones were not suitable for children suffering from 17 hydroxylase deficiency before puberty.

CPAP结合肺泡表面活性物质治疗新生儿呼吸窘迫综合征的疗效观察

目的分析CPAP结合肺泡表面活性物质治疗新生儿呼吸窘迫综合征的临床疗效。方法选取我院2016年2月—2017年4月收治的新生儿呼吸窘迫综合征患儿40例作为研究对象。通过抽签法,将其均分为观察组和对照组,每组各20例患儿。对照组患儿采用肺泡表面活性物质进行治疗,观察组患儿采用CPAP结合肺泡表面活性物质进行治疗。结果治疗前,观察组和对照组患者PaO_2、PaCO_2、PaO_2/FiO_2和pH值比较,差异无统计学意义(P>0.05)。治疗后,观察组患者PaO_2、PaCO_2、PaO_2/FiO_2和pH值与对照组比较,差异具有统计学意义(P<0.05)。结论新生儿呼吸窘迫综合征经CPAP结合肺泡表面活性物质治疗疗效确切。

路标

一场铺天盖地连续二十四小时的漠风之后，我们迷路了。连向导也一筹莫展。这场大风把整个沙漠世界改变了。这是二十世纪五十年代初期，野外作业的设备简陋，连个普通的报话机都没有，与外界无法联系。我们一行五人，七峰骆驼，估算了一下，食品和水，预计可维持三至五天。

CHARACTERISTICS AND CAUSE ANALYSIS OF WESTERN PACIFIC SUBTROPICAL HIGH DURING THE HUAIHE RIVER FLOODS IN 2003

1 INTRODUCTION In summer, different assembly of the intensity, location and vertical structure of the subtropical high and the earlier/later time of its seasonal northwards jump bring about different precipitation patterns over China. Therefore, subtropical high activity and its cause during the occurrence of extreme climatic event over China and the cause of China drought/flood are studied to improve weather forecasting.

Characterization of lipid parameters in diabetic and non-diabetic atherosclerotic patients

Background ＆ Objective The relationship between lipid profile perturbation and diabetes associated complications has long been an area of interest. Dyslipidemia is a potent predictor of cardiovascular morbidity and mortality in diabetic patients. The aim of present study was to investigate relationship between aging and lipid profiles in diabetic and non-diabetic atherosclerotie patients. Methods Five hundred and seventy six individuals （45-75 year age） participated in this study. Among these, 192 were having history of diabetes mellitus and atherosclerosis. Individuals are categorized on the base of health （normal, non-diabetic atheroselerosis, diabetic atherosclerosis） and age （45-55 years, 56~55 years, and 66-75 years）. All the participants were subjected to the procedures like a detailed history, biochemical analysis for fasting blood sugar, hemoglobin Alc, total cholesterol （TC）, triglycerides （TG）, low-density lipoprotein-（LDL）, very low-density lipoprotein （VLDL） and high-density lipoprotein （HDL）. All these parameters were compared between diabetic and non-diabetic atherosclerotic patients of all three age groups. TC/HDL and LDL/HDL were also calculated. Results Diabetic atherosclerotic individuals （both males and females） had high level of TC, TG, LDL, VLDL and low level of HDL in comparison to non-diabetic atherosclerotie and normal control individuals. Among all three age groups, lipoprotein abnormality was observed to be more frequent in females than males. There was a significant increase in TC/HDL and LDL/HDL ratio in diabetic atherosclerotic subjects compared to age and sex matched non-diabetic atherosclerotic and normal control. Conclusions Degree of dyslipidemia increases with increase in age in both genders. Female are more prone to diabetic dyslipidemia and hence have more risk of developing atherosclerosis with increasing age.

Quantitative analysis of magnetic anomaly of reinforcements in bored in-situ concrete piles

We quantitatively study magnetic anomalies of reinforcement rods in bored insitu concrete piles for the first time and summarized their magnetic anomaly character. Key factors such as measuring borehole orientation, borehole-reinforcement distance, and multiple-section reinforcement rods are discussed which contributes valid and quantitative reference for using the magnetic method to detect reinforcement rods. Through tests with model piles, we confirm the accuracy of theoretical computations and then utilize the law discovered in theoretical computations to explain the characteristics of the actual testing curves. The results show that the Za curves of the reinforcement rod reflect important factors regarding the reinforcement rods, such as rod length, change of reinforcement ratio, length of overlap, and etc. This research perfects the magnetic method for detecting reinforcement rods in bored in-situ concrete piles and the method has great importance for preventing building contractor fraud.

Cronkhite-Canada syndrome associated with myelodysplastic syndrome

We report a case of Cronkhite-Canada syndrome(CCS)associated with myelodysplastic syndrome(MDS).A 54-year-old woman,diagnosed as MDS the prior year after evaluation of anemia,visited our hospital with the chief complaint of epigastric discomfort.She also had dysgeusia,alopecia,atrophic nail change,and pigmentation of the palm,all of which began several months ago.Blood tests revealed severe hypoalbuminemia.Colonoscopy(CS)showed numerous,dense,red polyps throughout the colon and rectum.Biopsy specimens showed stromal edema,infi ltration of lymphocytes,and cystic dilatation of the crypt.Her clinical manifestations and histology were consistent with CCS.We prescribed corticosteroids,which dramatically improved her physical findings,laboratory data,and endoscopic fi ndings.This is the first report of CCS in a patient with MDS.

Cardiac arrhythmia and heart failure： From bench to bedside

Cardiac arrhythmia is an abnormal rate and/or rhythm of a heart due to its abnormal electrical impulse origination and/or propagation. Various etiologies can cause arrhythmias. Heart failure （HF） is a clinical syndrome due to an impaired heart that can not pump sufficient blood to meet the systemic metabolic needs.

Decomposition of the Unsteady Wave Patterns for Bessho form Translating-Pulsating Source Green Function

In order to interpret the physical feature of Bessho form translating-pulsating source Green function, the phase function is extracted from the integral representation and stationary-phase analysis is carried out in this paper. The complex characteristics of the integral variable and segmentation of the integral intervals are discussed in m complex plane. In θ space, the interval [-π/2+φ,-π/2+φ-iε] is dominant in the near-field flow, and there is a one-to-one correspondence between the real intervals in m space and the unsteady wave patterns in far field. If 4τ>1(τ is the Brard number), there are three kinds of propagation wave patterns such as ring-fan wave pattern, fan wave pattern and inner V wave pattern, and if 0<4τ<1, a ring wave pattern, an outer V and inner V wave pattern are presented in far field. The ring-fan or ring wave pattern corresponds to the interval [-π+α,-π/2+φ] for integral terms about k2, and the fan or outer V wave pattern and inner V wave pattern correspond to [-π+α,-π/2) and(-π/2,-π/2+φ] respectively for terms about k1. Numerical result shows that it is beneficial to decompose the unsteady wave patterns under the condition of τ≠0 by converting the integral variable θ to m. In addition, the constant-phase curve equations are derived when the source is performing only pulsating or translating.

FEATURES AND COMPARISONS OF THE QUASI-BIENNIAL VARIATIONS IN THE ASIA-PACIFIC MONSOON SUBSYSTEMS

The National Centers for Environmental Prediction (NCEP) reanalysis data, Climate Diagnostics Center Merged Analysis of Precipitation (CMAP) results, and NOAA Extended Reconstructed Sea Surface Temperature (SST), have been utilized in this paper to study the quasi-biennial variations in Asia-Pacific monsoon subsystems and associated SST anomalies (SSTA) and wind anomalies. Four monsoon indices are computed from NCEP/ National Center for Atmospheric Research (NCAR) reanalysis to represent the South Asian monsoon (SAM), South China Sea summer monsoon (SCSSM), Western North Pacific monsoon (WNPM) and East Asian monsoon (EAM), respectively. The quasi-biennial periods are very significant in Asia-Pacific monsoons (as discovered by power spectrum analysis), and for SAM and EAM---with moderate effects by El Ni?o-Southern Oscillation (ENSO)---the quasi-biennial periods are the most important factor. For SCSSM and WNPM (once again due to the effects of ENSO), the quasi-biennial periods are of secondary durations. There are obvious interdecadal variations in the quasi-biennial modes of the Asia-Pacific monsoon, so in the negative phase the biennial modes will not be significant or outstanding. The wind anomalies and SSTA associated with the biennial modes are very different in the SAM, WNPM and EAM regions. Since the WNPM and SCSSM are very similar in the biennial modes, they can be combined into one subsystem, called SCS/WNPM.

Analysis of Abnormal Characteristics of Regional Crustal Deformation before the Menyuan MS6.4 Earthquake by GPS Continuous Data

In order to study the characteristics of crustal deformation around the epicenter before the 2016 M_S6. 4 Menyuan earthquake,the GPS continuous stations of the period from 2010 to 2016 were selected according to the observation data of the tectonic environment monitoring network in Chinese Mainland. The deformation characteristics of the crust before the earthquake were discussed through inter-station baseline time series analysis and the strain time series analysis in the epicentral region. The results show that a trend turn of the baseline movement state around the epicenter region occurred after 2014,and the movement after 2014 reflects an obvious decreasing trend of compressional deformation.During this period,the stress field energy was in a certain accumulation state. Since the beginning of 2014,the EW-component linear strain and surface strain rate weakened gradually before the earthquake. It shows that there was an obvious deformation deficit at the epicentral area in the past two years,which indicates that the region accumulated a high degree of strain energy before the earthquake. Therefore,there was a significant background change in the area before the earthquake. The results of the study can provide basic research data for understanding the seismogenic process and mechanism of this earthquake.

CHARACTERISTICS OF ZONAL ANOMALY OF ANNUAL PRECIPITATION IN THE NORTHEASTERN CHINA

The characteristics of zonal anomaly and change rule of temporal distribution of annual precipitation in the northeastern China are revealed in this paper with EOF (Empirical Orthogonal Function) and REOF (Rotated Empirical Orthogonal Function) methods and results are drawn in the standard relief maps with GIS technology for practical application. Data used in the study were obtained from 208 meteorological stations over the northeastern China from 1961 to 2001. EOF results show that the first 3 loading vectors could give entire spatial anomaly structure of annual precipitation. In the Northeast Plain including the Songneng Plain and the Liaohe Plain, there is a regional compatibility (whether wet or dry) of annual precipitation change and this precipitation pattern has occurred since the late 1980s to the present. There also exist annual precipitation patterns of wet (or dry) in south and dry (or wet) in north and wet (or dry) in east and dry (or wet) in west. REOF results display 8 principal precipitation anomaly areas by the first 8 rotated loading vectors: the west plain, the Liaodong hills, the Sanjiang Plain, the Liaoxi hills, the Changbai Mountains, the Hulun Buir Plateau, the southwest plateau and the Liaodong Peninsula.

Expression of DLK1 Gene in the Bone Marrow Cells of Patients with Myelodysplastic Syndromes and Its Clinical Significance

Objective This study aims to investigate the expression of delta-like 1 （DLK1） gene in the bone marrow cells of patients with myelodysplastic syndromes （MDS） and to explore its molecular characteristics for the early diagnosis of MDS. Methods The expression of DLK1 mRNA in the bone marrow cells of cases with MDS, acute myeloid leukemia （AML）, and normal control groups were measured by real-time polymerase chain reaction and were analyzed for clinical significance. Results Significantly higher expression of DLK1 mRNA was observed in the bone marrow cells of MDS patients （0.7342±0.3652） compared with the normal control group （0.4801±0.1759） （P〈0.05）. The expression of DLK1 mRNA had a positive correlation with the proportion of bone marrow blasts （r=0.467, P〈0.05）. Moreover, DLK1 mRNA expression was significantly increased as MDS progressed （P〈0.05）. Patients with abnormal karyotypes exhibited significantly higher expression of DLK1 mRNA （0.9007±0.4334） than those with normal karyotypes （0.6411±0.2630） （P〈0.05）. Subsequently, patients with highly expressed DLK1 （≥0.8） presented significantly higher malignant clone burden （0.4134±0.3999） than those with lower DLK1 expression （〈0.8）,（0.1517±0.3109）, （P〈0.05）. Conclusions The DLK1 gene was highly expressed in MDS patients, and was increased as MDS progressed. The expression of DLK1 mRNA was positively correlated with the proportion of the bone marrow blasts. A high expression of DLK1 gene suggested a higher malignant clone burden of MDS.

Characteristic Analysis of Anomalies of Strong Earthquakes along the Tancheng-Lujiang Fault Zone and Both Its Sides

This article made a systematic statistical analysis on the duration,spatial distribution,form,range,type and reliability of precursory anomalies based on the observations of precursors of 24 moderate-strong earthquakes occurring along the Tancheng-Lujiang fault zone and its bilateral areas in Shandong,Liaoning,Hebei,Jiangsu and Jiangxi Provinces in the period from 1966 to 2005. Results show that:( 1) For M7. 0 and M6. 0earthquakes,med-term abnormities are the greatest in number,short-term abnormities come second,and imminent anomalies are the least. For M5. 0 earthquakes,short-term abnormities are often the most in number,imminent anomalies come second,and the med-term ones are the least.( 2) Precursory anomalies are periodical,part of the med and short-term anomalies are shown as short-term and imminent anomalies during their development.( 3) The development of precursor shows quasi-synchronism; the closer to earthquake occurrence time,the more turning changes of anomalies will appear.( 4)Anomalies mainly occur within an epicenter distance of 100 km, showing a relative concentrated distribution in space,and the shorter the distance to epicenter,the higher the anomaly station / item rate.( 5) The spatial distribution of anomalies is relatively correlated to the strike of structures,having a good consistency with the structure.( 6)There is no significant correlation between duration of abnormities and the epicenter distance.( 7) The higher the magnitude of the earthquake,the greater the amplitude of the abnormities measured with the same observation approach.( 8) In terms of the itemsof the observations,fluid abnormities are the greatest in number,followed by deformation and electromagnetism observations.( 9) For all observation items,med and short-term abnormities make up the majority and short-term and imminent anomalies the minority.( 10) In fluid,deformation and electromagnetism observations,fairly reliable anomalies are about double the number of reliable anomalies.

Abnormal expression of PACAP gene in patients with myelodysplastic syndrome

Objective： To explore the expression pattern of PACAP gene in patients with myelodysplastic syndrome （MDS）. Methods： The expression pattern of PACAP gene in CD34＋ cells from MDS patients was determined by microarray, confirmed in expanding samples by quantitative real-time PCR in bone marrow mononuolear cells. Results： The transcription of PACAP gene was found significantly down-regulated in patients with MDS in comparison with that in control samples, with a means of 220.1 in MDS-RA and 116.8 in MDS-RAEB （P 〈 0.05 ）. Conclusion： PACAP gene is expressed significantly lower in patients with MDS.

The Preliminary Analysis of the Characteristics of Geomagnetic Harmonic Wave Amplitude Ratios before the Gaoyou-Baoying MS4.9 Earthquake

In this paper,the Gaoyou-Baoying M_S4.9 earthquake was analyzed by the geomagnetic harmonic wave amplitude ratios method. The earthquake was an isolated seismic event,before and after which there were no other earthquakes occurred in this region. The dense distribution of geomagnetic observataries provided an advantage condition for the analysis of characteristics of the geomagnetic harmonic amplitude ratios. The analysis results verify the former knowledge of anomaly characteristics of the geomagnetic harmonic amplitude ratio,that is,the anomalous characteristics of the earthquake mostly appeared during the decline-turning-recovery rising process. The results also show that the change of the anomalies was asynchronous at the observatories close to the epicenter, namely, the anomalous characteristics were different between the H and the D components,as well as between the long and short periods.

Large-vessel thrombosis in intestinal Behet's disease complicated with myelodysplastic syndrome and trisomy 8

Behet's disease is characterized by recurrent oral ulcers, genital ulcers, uveitis and skin lesions. Myelodysplastic syndrome (MDS) is characterized by problems due to ineffective hematopoiesis. Several studies have identified a relationship between MDS and Behet's disease, especially intestinal Behet's disease. Trisomy 8 seems to play an important role in these disorders as well. The present case was a 24-year-old woman who had a huge tonsil ulcer with initial symptoms of odynophagia and intermittent fever. We also noted folliculitis on her upper back. Five days later, she began to experience diarrhea and abdominal pain. Abdominal computed tomography and subsequent surgery revealed ileum perforation and enterocolitis with multiple ulcers. Later, she was admitted again for a vulvar suppurative ulcer and suspicious Bartholin's cyst infection. The patient's clinical presentations met the criteria for Behet's disease. Six months after the bowel perforation event, we noted the development of pancytopenia in a routine laboratory examination. All the examinations led to the diagnosis of MDS with trisomy 8. The most unusual finding was that multiple large vessel thrombi developed during follow-up. Previous studies have suggested that trisomy 8 in MDS leads to concurrent intestinal Behet's disease. Moreover, the inflammatory and immune genes related to thrombus formation are overexpressed in cases of MDS with trisomy 8. Trisomy 8 must play a role in thrombosis. Further studies are needed to help clarify the pathophysiology and pathogenesis of these disorders.

TET2 Expression in Bone Marrow Mononuclear Cells of Patients with Myelodysplastic Syndromes and Its Clinical Significances

Objective To investigate the expression of TET2 mRNA and protein in the bone marrow mononuclear cells （BMMNC） of patients with myelodysplastic syndrome （MDS） and its clinical significance. Methods The expression of TET2 mRNA and protein in bone marrow mononuclear cells （BMMNC） of 32 patients with MDS and 20 healthy donors was examined by qPCR and Western blot. Results The expression of TET2 mRNA in BMMNC was down-regulated in MDS patients compared with the donor group [（0.41±0.28）% vs. （1.07±0.56）%] （P〈0.001）. Compared with lower expression group （TET2〈0.4） [（6.53±6.17）%], patients with higher expression of TET2 ≥0.4） presented significantly lower proportion of bone marrow blasts [（1.21±1.56）%1 （P〈0.05）. The expression of TET2 mRNA in BMMNC of MDS patients was inversely correlated with malignant clone burden （t=--0.398, P〈0.05） and IPSS r=-0.412, P〈0.05）. The expression of TET2 protein was down-regulated in MDS patients compared with that in the donor group. Conclusions The mRNA and protein expression of TET2 in BMMNC of MDS patients is decreased, which might be useful as an important parameter for the evaluation of MDS clone burden.

The Characteristics of the Precursory Anomaly prior to the Yiliang Earthquakes,Yunnan,China on September 7,2012

An analysis was carried out on the seismic activity and the precursory anomaly prior to the earthquakes in Yiliang on September 7,2012. The characteristics of the seismic activity,the dynamic changes of underground fluid and deformation were investigated. As a result of the investigation,we found that: before the earthquake,the seismicity level of M4. 0earthquakes had enhanced,and seismic gap of a small earthquake had appeared; the precursory anomalies emerged about 1 year before the earthquake; there was phenomenon of short-term anomaly migrating from the periphery to the epicenter area; the imminent anomaly appeared in a relatively concentrated period of time, a week before the earthquake. The research has shown a significant guidance for the analysis and prediction of strong earthquakes( Ml> 5. 0).