Background: The diagnosis of small- bowel Crohn’ s disease sometimes is dif ficult and may be missed by conventional imaging studies. Capsule endoscopy migh t identify small- bowel disease undetected by other investi...Background: The diagnosis of small- bowel Crohn’ s disease sometimes is dif ficult and may be missed by conventional imaging studies. Capsule endoscopy migh t identify small- bowel disease undetected by other investigations. Methods: Pa tients with or without known Crohn’ s disease who were suspected to have small - bowel Crohn’ s disease were prospectively evaluated with push enteroscopy, e nteroclysis, and capsule endoscopy. Each examiner was blinded to results of othe r investigations. Referring doctors were required to complete questionnaires bef ore and after the investigations. Results: Twenty- two patients were known to h ave Crohn’ s disease (Group 1), and 21 were suspected to have small- bowel Cro hn’ s disease (Group 2). In Group 1, capsule endoscopy detected more erosions t han the other two investigations (p< 0.001). In Group 2, a new diagnosis of Croh n’ s disease was made in two patients, but there was no significant difference in yield compared with the other two investigations. Referring physicians rated the usefulness of capsule endoscopy a s 4.4 on a scale of 5. Capsule endoscopy changed management for 30 patients (70 % ). Conclusions: Capsule endoscopy has a higher yield than push enteroscopy an d enteroclysis in patients with known Crohn’ s disease when small- bowel mucos al disease is suspected, and this leads to a change in management in the majorit y of these patients.展开更多
文摘Background: The diagnosis of small- bowel Crohn’ s disease sometimes is dif ficult and may be missed by conventional imaging studies. Capsule endoscopy migh t identify small- bowel disease undetected by other investigations. Methods: Pa tients with or without known Crohn’ s disease who were suspected to have small - bowel Crohn’ s disease were prospectively evaluated with push enteroscopy, e nteroclysis, and capsule endoscopy. Each examiner was blinded to results of othe r investigations. Referring doctors were required to complete questionnaires bef ore and after the investigations. Results: Twenty- two patients were known to h ave Crohn’ s disease (Group 1), and 21 were suspected to have small- bowel Cro hn’ s disease (Group 2). In Group 1, capsule endoscopy detected more erosions t han the other two investigations (p< 0.001). In Group 2, a new diagnosis of Croh n’ s disease was made in two patients, but there was no significant difference in yield compared with the other two investigations. Referring physicians rated the usefulness of capsule endoscopy a s 4.4 on a scale of 5. Capsule endoscopy changed management for 30 patients (70 % ). Conclusions: Capsule endoscopy has a higher yield than push enteroscopy an d enteroclysis in patients with known Crohn’ s disease when small- bowel mucos al disease is suspected, and this leads to a change in management in the majorit y of these patients.
