AIM:To report the results of a medical management of sphincter of oddi dysfunction(SOD) after an intermediate follow-up period.METHODS:A total of 59 patients with SOD(2 men and 57 women,mean age 51 years old) were inc...AIM:To report the results of a medical management of sphincter of oddi dysfunction(SOD) after an intermediate follow-up period.METHODS:A total of 59 patients with SOD(2 men and 57 women,mean age 51 years old) were included in this prospective study.After medical treatment for one year,the patients were clinically re-evaluated after an average period of 30 mo.RESULTS:The distribution of the patients according to the Milwaukee's classification was the following:11 patients were type 1,34 were type 2 and 14 were type 3.Fourteen patients underwent an endoscopic sphincterotomy(ES) after one year of medical treatment.The median intermediate follow-up period was 29.8 ± 3 mo(3-72 mo).The initial effectiveness of the medical treatment was complete,partial and poor among 50.8%,13.5% and 35%,respectively,of the patients.At the end of the follow-up period,37 patients(62.7%) showed more than 50% improvement.The rate of improvement in patients who required ES was not significantly different compared with the patients treated conservatively(64.2% vs 62.2%,respectively).CONCLUSION:Our study confirms that conservative medical treatment could be an alternative to endoscopic sphincterotomy because,after an intermediate follow-up period,the two treatments show the same success rates.展开更多
In bilateral pbeochromocytoma, localization of the dominant adrenal is challenging but highly important since the removal of dominant side can markedly improve cardiovascular outcomes. To demonstrate the usefulness of...In bilateral pbeochromocytoma, localization of the dominant adrenal is challenging but highly important since the removal of dominant side can markedly improve cardiovascular outcomes. To demonstrate the usefulness of glucagon-stimulated BAVS （bilateral adrenal venous sampling） in determining the dominant adrenal to be removed, the authors reviewed records of patients who underwent BAVS with glucagon stimulation from 1997-2010. Nineteen out of 44 patients were diagnosed with bilateral pheochromocytoma. Mean age at diagnosis was 33 ± 14 years. Duration of hypertension was 5 ± 6 years with highest systolic BP （blood pressure） of 186 ±30 mmHg and diastolic BP of 113 ±18 mmHg. Headache （68%） is the most common symptom followed by paroxysmal hypertension （58%）. Majority were taking 〉 3 anti-hypertensive drugs. On glucagon-stimulated BAVS, 63% had right adrenal dominance. Three patients, who were hypertensive for 1, 6 and 12 years, underwent removal of the dominant adrenal. On follow-up （mean period = 36 months）, there was marked improvement in BP control [pre-op vs. post-op： （systolic） 160-240 mmHg vs. 120-150 mmHg; （diastolic） 90-110 mmHg vs. 70-90 mmHg] and reduction in number of anti-hypertensive medications （from 3-5 to 2 classes of drugs）. BAVS with glucagon stimulation is a valuable tool in the identification of the dominant adrenal to be removed in patients with bilateral pheochromocytoma to alleviate chronic hypertension.展开更多
This work investigates the boreal-summer intraseasonal variability(ISV)of the precipitation over the lower reaches of the Yangtze River basin(LYRB)during 1979–2016,based on daily Climate Prediction Center global prec...This work investigates the boreal-summer intraseasonal variability(ISV)of the precipitation over the lower reaches of the Yangtze River basin(LYRB)during 1979–2016,based on daily Climate Prediction Center global precipitation data.The ISV of the summer monsoon rainfall over the LYRB is mainly dominated by the lower-frequency 12–20-day variability and the higher-frequency 8–12-day variability.The lower-frequency variability is found to be related to the northwestwardpropagating quasi-biweekly oscillation(QBWO)over the western North Pacific spanning the South China Sea(SCS)and Philippine Sea,while the higher-frequency variability is related to the southeastward propagating midlatitude wave train(MLWT).Moreover,not each active QBWO(MLWT)in the SCS(East Asia)can generate ISV components of the precipitation anomaly over the LYRB.The QBWO can change the rainfall significantly with the modulation of mean state precipitation,while the quasi-11-day mode mainly depends on the intensity of the MLWT rather than the mean precipitation change.These findings should enrich our understanding of the ISV of the East Asian summer monsoon and improve its predictability.展开更多
The effect of two diets containing fish acid silage were studied, the first one offered as dry diet and the second one as a wet diet, in final culture cycle of PactS. Previous experiences showed that diets without fis...The effect of two diets containing fish acid silage were studied, the first one offered as dry diet and the second one as a wet diet, in final culture cycle of PactS. Previous experiences showed that diets without fishmeal maintain same growth rate in semi intensive system, compared to diets containing 8% and 20% fish meal. Feeding trials were carried out in CENADAC （27°32′ S, 58030＇ W） in a semi intensive pond culture system for 122 days. Two experimental feed including fish silage, a liquid product obtained of fish residues treated by enzymes action, were formulated. Fish silage was prepared by mincing and blending fish viscera with sufficient formic acid （2.11% v/w） to attain a stable pH of 3.5. Fish were daily fed initially with the dry ration at 1.3% bw/d and at a rate of 0.55 g of protein/100 g of fish with the wet ration. At the end of the experience the average weight observed for dry fed fish was 1,513.5 g and 1,560.3 g for those wet fed. The daily growth was 3.69 g/d for the first group and 3.9 g/d for the second one. The final FCR was 2.72 and 3.01 for each group without significant differences. These results showed that it is possible to grow out paco with wet self made feed without fish meal and with similar growth that those fed dry diet.展开更多
文摘AIM:To report the results of a medical management of sphincter of oddi dysfunction(SOD) after an intermediate follow-up period.METHODS:A total of 59 patients with SOD(2 men and 57 women,mean age 51 years old) were included in this prospective study.After medical treatment for one year,the patients were clinically re-evaluated after an average period of 30 mo.RESULTS:The distribution of the patients according to the Milwaukee's classification was the following:11 patients were type 1,34 were type 2 and 14 were type 3.Fourteen patients underwent an endoscopic sphincterotomy(ES) after one year of medical treatment.The median intermediate follow-up period was 29.8 ± 3 mo(3-72 mo).The initial effectiveness of the medical treatment was complete,partial and poor among 50.8%,13.5% and 35%,respectively,of the patients.At the end of the follow-up period,37 patients(62.7%) showed more than 50% improvement.The rate of improvement in patients who required ES was not significantly different compared with the patients treated conservatively(64.2% vs 62.2%,respectively).CONCLUSION:Our study confirms that conservative medical treatment could be an alternative to endoscopic sphincterotomy because,after an intermediate follow-up period,the two treatments show the same success rates.
文摘In bilateral pbeochromocytoma, localization of the dominant adrenal is challenging but highly important since the removal of dominant side can markedly improve cardiovascular outcomes. To demonstrate the usefulness of glucagon-stimulated BAVS （bilateral adrenal venous sampling） in determining the dominant adrenal to be removed, the authors reviewed records of patients who underwent BAVS with glucagon stimulation from 1997-2010. Nineteen out of 44 patients were diagnosed with bilateral pheochromocytoma. Mean age at diagnosis was 33 ± 14 years. Duration of hypertension was 5 ± 6 years with highest systolic BP （blood pressure） of 186 ±30 mmHg and diastolic BP of 113 ±18 mmHg. Headache （68%） is the most common symptom followed by paroxysmal hypertension （58%）. Majority were taking 〉 3 anti-hypertensive drugs. On glucagon-stimulated BAVS, 63% had right adrenal dominance. Three patients, who were hypertensive for 1, 6 and 12 years, underwent removal of the dominant adrenal. On follow-up （mean period = 36 months）, there was marked improvement in BP control [pre-op vs. post-op： （systolic） 160-240 mmHg vs. 120-150 mmHg; （diastolic） 90-110 mmHg vs. 70-90 mmHg] and reduction in number of anti-hypertensive medications （from 3-5 to 2 classes of drugs）. BAVS with glucagon stimulation is a valuable tool in the identification of the dominant adrenal to be removed in patients with bilateral pheochromocytoma to alleviate chronic hypertension.
基金This work was supported by the National Natural Science Foundation of China[grant number 41420104002]the Natural Science Foundation of Jiangsu Province[grant numbers BK20150907 and 14KJA170002].
文摘This work investigates the boreal-summer intraseasonal variability(ISV)of the precipitation over the lower reaches of the Yangtze River basin(LYRB)during 1979–2016,based on daily Climate Prediction Center global precipitation data.The ISV of the summer monsoon rainfall over the LYRB is mainly dominated by the lower-frequency 12–20-day variability and the higher-frequency 8–12-day variability.The lower-frequency variability is found to be related to the northwestwardpropagating quasi-biweekly oscillation(QBWO)over the western North Pacific spanning the South China Sea(SCS)and Philippine Sea,while the higher-frequency variability is related to the southeastward propagating midlatitude wave train(MLWT).Moreover,not each active QBWO(MLWT)in the SCS(East Asia)can generate ISV components of the precipitation anomaly over the LYRB.The QBWO can change the rainfall significantly with the modulation of mean state precipitation,while the quasi-11-day mode mainly depends on the intensity of the MLWT rather than the mean precipitation change.These findings should enrich our understanding of the ISV of the East Asian summer monsoon and improve its predictability.
文摘The effect of two diets containing fish acid silage were studied, the first one offered as dry diet and the second one as a wet diet, in final culture cycle of PactS. Previous experiences showed that diets without fishmeal maintain same growth rate in semi intensive system, compared to diets containing 8% and 20% fish meal. Feeding trials were carried out in CENADAC （27°32′ S, 58030＇ W） in a semi intensive pond culture system for 122 days. Two experimental feed including fish silage, a liquid product obtained of fish residues treated by enzymes action, were formulated. Fish silage was prepared by mincing and blending fish viscera with sufficient formic acid （2.11% v/w） to attain a stable pH of 3.5. Fish were daily fed initially with the dry ration at 1.3% bw/d and at a rate of 0.55 g of protein/100 g of fish with the wet ration. At the end of the experience the average weight observed for dry fed fish was 1,513.5 g and 1,560.3 g for those wet fed. The daily growth was 3.69 g/d for the first group and 3.9 g/d for the second one. The final FCR was 2.72 and 3.01 for each group without significant differences. These results showed that it is possible to grow out paco with wet self made feed without fish meal and with similar growth that those fed dry diet.
