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自动平衡灌注摘出先天性白内障的临床观察
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作者 丁相奇 雷智 +2 位作者 王峰 高永杰 李援东 《眼科研究》 CSCD 北大核心 2001年第5期455-456,共2页
观察自动平衡灌注系统摘出先天性白内障的手术效果。方法 36例40眼先天性白内障患儿用平衡灌注系统摘出并植入后房人工晶状体,并与同期或既往40眼先天性白内障患者行现代囊外摘出人工晶状体植入作对比。结果 自动平衡灌注组术中... 观察自动平衡灌注系统摘出先天性白内障的手术效果。方法 36例40眼先天性白内障患儿用平衡灌注系统摘出并植入后房人工晶状体,并与同期或既往40眼先天性白内障患者行现代囊外摘出人工晶状体植入作对比。结果 自动平衡灌注组术中、术后并发症较传统术式明显减少,尤其是后发障的发生前者仅为30%,后者为57.1%(P<0.01)。结论 自动平衡灌注以良好的前房稳定性,较轻的术后反应,及晶状体皮质的彻底清除提高了先天性白内障的手术效果。 展开更多
关键词 先天性白内障 平衡灌注 眼内镜 白内障摘除术
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EXPERIMENTAL STUDY ON TIME EFFECT OF WET DRILLING PILE 被引量:2
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作者 程晔 龚维明 +1 位作者 戴国亮 季杰 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2008年第4期311-317,共7页
Time effect of wet drilling pile is investigated through the static load experiment on pile No. 22 of Guanhe Bridge. Post-grouting under pile tip is adopted in the project. To study the bearing performance of the pile... Time effect of wet drilling pile is investigated through the static load experiment on pile No. 22 of Guanhe Bridge. Post-grouting under pile tip is adopted in the project. To study the bearing performance of the pile, the self-balanced method is used and two load cells are assembled in the pile body. The experiments are carried out before and after post-grouting. The upper part of the pile is not influenced by post-grouting under the pile tip. Experimental results of the upper part of the pile show that the bearing capacity and the rigidity of wet drilling pile increase with time passing on. Analysis results show the time effect of wet drilling pile is influenced by many factors, such as alteration of stress field around pile, characteristics of soil around pile, variety of mud cake, and property of residue under pile tip. 展开更多
关键词 bearing capacity drilling pile time effect self-balanced
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Conversion factor analysis of self-balanced loading test of cast-in-situ piles based on analogue test method 被引量:3
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作者 Li Jianhang Li Xiaojuan +2 位作者 Gao Luchao Dai Guoliang Wu Weiguo 《Journal of Southeast University(English Edition)》 EI CAS 2019年第2期185-190,共6页
Based on the characteristics of pile-soil interaction and the Mohr-Coulomb strength theory,a new method of determining the side friction at a pile-soil interaction is proposed.Combined with the actual engineering case... Based on the characteristics of pile-soil interaction and the Mohr-Coulomb strength theory,a new method of determining the side friction at a pile-soil interaction is proposed.Combined with the actual engineering cases,the effectiveness of the analogue test method is verified by comparing it with the traditional anchor pile method and self-balanced method.Taking the self-balanced test of the bridge pile foundation in the Songhua River as an example,the conversion factor of sandy soil and weathered mudstone are confirmed by the analogue test method.The results show that the conversion factor of sandy soil and weathered mudstone in the Songhua River area should consider the geological conditions and the construction technology,etc.The standard values are relatively conservative.It is suggested that the engineering application should be properly revised.The recommended range of the conversion factor of sandy soil in this area is 0.65 to 0.85,and that of weathered mudstone is 1.0. 展开更多
关键词 cast-in-situ piles self-balanced method analogue test method Mohr-Coulomb strength theory conversion factor
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Isoflurane preserves energy balance in isolated hepatocytes during in vitro anoxia/reoxygenation 被引量:4
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作者 QuanLi Wei-FengYu +5 位作者 Mai-TaoZhou XinLu Li-QunYang MingZhu Jian-GangSong Jun-HuaLu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第25期3920-3924,共5页
AIM: To investigate the protective effect of isoflurane on energy balance in isolated hepatocytes during in vitro anoxia/reoxygenation, and to compare isoflurane with halothane. METHODS: Hepatocytes freshly isolated f... AIM: To investigate the protective effect of isoflurane on energy balance in isolated hepatocytes during in vitro anoxia/reoxygenation, and to compare isoflurane with halothane. METHODS: Hepatocytes freshly isolated from fed rats were suspended in Krebs-Henseleit buffer, and incubated in sealed flasks under O2/CO2 or N2/CO2 (95%/5%, V/V) for 30 or 60 min, followed by 5 or 10 min of reoxygenation, with an added volatile anesthetic or not. ATP, ADP, and adenosine monophosphate in hepatocytes were determined by high performance liquid chromatography, and energy charge was calculated. RESULTS: During 30 min of anoxia, the energy charge and total adenine nudeotide steadily increased with the isoflurane dose from 0 to 2 minimum alveolar anesthetic concentration (MAC), then decreased from 2 to 3 MAC. In short incubations (30-35 min) at 1 MAC isoflurane, energy charge modestly decreased during anoxia, which was partially prevented by isoflurane and completely reversed by reoxygenation, and total adenine nudeotide did not decrease. In long incubations (60-70 min), both energy charge and total adenine nudeotide greatly decreased during anoxia, with partial and no reversal by reoxygenation, respectively. Isoflurane partly prevented decreases in both energy charge and total adenine nudeotide during anoxia and reoxygenation. In addition, 1 MAC isoflurane obviously increased ATP/ADP, which could not be changed by 1 MAC halothane. CONCLUSION: Isoflurane partially protects isolated hepatocytes against decreases in both energy charge and total adenine nudeotide during short (reversible) or long (irreversible) anoxia. 展开更多
关键词 ISOFLURANE HEPATOCYTES ANOXIA Energy balance
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糖尿病大鼠离体心脏对缺血/再灌注的耐受性 被引量:4
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作者 刘涛 徐美英 +3 位作者 都大伟 尹尧 张玉良 陈红 《中华麻醉学杂志》 CAS CSCD 北大核心 2005年第2期126-129,共4页
目的评价糖尿病大鼠离体心脏缺血/再灌注后心脏功能的改变。方法链佐星(60mg/kg)诱导的糖尿病大鼠16只(D组),年龄匹配的健康雄性SD大鼠10只(C组),戊巴比妥钠(60mg/kg)麻醉后快速取出心脏,接上主动脉插管置于Langendorg装置上,Krebs-H... 目的评价糖尿病大鼠离体心脏缺血/再灌注后心脏功能的改变。方法链佐星(60mg/kg)诱导的糖尿病大鼠16只(D组),年龄匹配的健康雄性SD大鼠10只(C组),戊巴比妥钠(60mg/kg)麻醉后快速取出心脏,接上主动脉插管置于Langendorg装置上,Krebs-Henseleit缓冲液逆行灌注。平衡灌注20min,待心率(HR)及冠脉流量平稳后夹闭灌注道,进行全心缺血30min,复灌40min。持续监测心肌心电活动、左心室压峰值(LVPSP)、左室舒张末压(LVEDP)和左室压力最大上升/下降速率(±dp/dtmax),计算左室发展压(LVDP=LVPSP-LVEDP),用LVDP×HR(RDPP)表示左室作功。结果与C组相比,基础状态下,D组大鼠心脏HR减慢,LVDP、RDPP和±dp/dtmax降低,LVEDP升高(P<0.05或0.01);再灌注后HR、LVDP、RDPP、冠脉流出液、±dp/dtmax等心功能指标恢复百分率升高,肌酸激酶活性降低(P<0.05或0.01);心脏缺血-停搏时间延长。结论糖尿病心脏基础心功能损伤严重,但对缺血/再灌注的耐受性增强。 展开更多
关键词 糖尿病大鼠 缺血/再灌注 耐受性 离体心脏 Langendorff 心率(HR) 左室舒张末压 LVDP 心脏缺血 0.05 戊巴比妥钠 主动脉插管 LVEDP 冠脉流出液 心功能指标 心功能损伤 心脏功能 SD大鼠 逆行灌注 平衡灌注 冠脉流量 全心缺血
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双胎输血综合征发病机制研究进展 被引量:5
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作者 郭咏冰 孙瑜 +1 位作者 杨慧霞 刘彩霞 《中华围产医学杂志》 CAS CSCD 2017年第8期607-610,共4页
双胎输血综合征(twin-twin transfusion syndrome,TTTS)是由于单绒毛膜双胎间血液不平衡灌注引起的,
关键词 双胎输血综合征 发病机制 平衡灌注 单绒毛膜 双胎间
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Effect of aqueous extract of Sanweitanxiang powder on calcium homeostasis protein expression in ischemic-reperfusion injury rat heart 被引量:2
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作者 Mei Yang Shuna Zhang +8 位作者 Shicun Ren Jinjun Wang Haixia Yun Sheng Yong Dejun Zhang Quanyu Yang Yiying Kou Dianxiang Lu Rili Ge 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2013年第3期355-360,共6页
OBJECTIVE: To investigate the underlying mechanism of reduced myocardial ischemia-reperfusion (I/R) injury in rats using the traditionalTibetan medicine Sanweitanxiang powder (SWTX). METHODS: Rats were randomly divide... OBJECTIVE: To investigate the underlying mechanism of reduced myocardial ischemia-reperfusion (I/R) injury in rats using the traditionalTibetan medicine Sanweitanxiang powder (SWTX). METHODS: Rats were randomly divided into six groups (n=10) as follows: (a) propranolol dinitrate control group, given propranolol dinitrate 0.02 g/kg for 10 days before I/R, (b) SWTX with a high dose group, given SWTX 1.5 g/kg for 10 days before I/R, (c) SWTX with a medium dose group, given SWTX 1.25 g/kg for 10 days before I/R, (d) sham group (Sham), in which the rat heart was exposed by pericardiotomy but without I/R, (e) SWTX with a low dose group, given SWTX 1.0 g/kg for 10 days before I/R, and (f) I/R injury group. Rats were intragastrically pretreated with propranolol dinitrate orSWTX. After that, the operation to cause ischemia and reperfusion was conducted.The histopathologic changes of rat hearts were observed by hematoxylin and eosin staining and transmission electron microscopy. Ca2+ homeostasis protein expression was determined by western blot. RESULTS: After SWTX pretreatment, the development of ultrastructural pathological changes from IR injury was attenuated. A decrease in the expression of B-cell lymphoma 2 associated X protein, and an increase in the expression of B-cell lymphoma 2 were observed. An increased activation of extracellular signal regulated kinases were found. Compared with the sham group, the expression of sarcoplasmic reticulum calcium-ATPase, phospholamban, and calsequestrin were all up-regulated after pretreatment with SWTX. CONCLUSION: The protective mechanism of SWTX pretreatment on myocardial I/R injury might be related to its effect on maintaining the balance of calcium homeostasis in rat heart. 展开更多
关键词 Reperfusion injury HOMEOSTASIS Pro-tein expression Sanweitanxiang powder
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