With the rapid development of urban rail transit,there have been an urgent problem of excessive stray current.Because the stray current distribution is random and difficult to verify in the field,we designed an improv...With the rapid development of urban rail transit,there have been an urgent problem of excessive stray current.Because the stray current distribution is random and difficult to verify in the field,we designed an improved stray current experimental platform by replacing the simulated aqueous solution with a real soil environment and by calculating the transition resistance by measuring the soil resistivity,which makes up for the defects in the previous references.Firstly,the mathematical models of rail-drainage net and rail-drainage netground were established,and the analytical expressions of current and voltage of rail,drainage net and other structures were derived.In addition,the simulation model was built,and the mathematical analysis results were compared with the simulation results.Secondly,the accuracy of the improved stray current experimental platform was verified by comparing the measured and simulation results.Finally,based on the experimental results,the influence factors of stray current were analyzed.The relevant conclusions provide experimental data and theoretical reference for the study of stray current in urban rail transit.展开更多
An airway pressure and flow data acquisition system is developed to investigate the approach to building the bi-level positive airway pressure BiPAP in a ventilator.A number of experiments under different breathing si...An airway pressure and flow data acquisition system is developed to investigate the approach to building the bi-level positive airway pressure BiPAP in a ventilator.A number of experiments under different breathing situations and states are conducted and the experimental data are recorded.According to the data from these experiments the variation characteristics of the pressure and flow are analyzed using Matlab. The data analysis results show that the pressure increases while the flow decreases in the expiratory phase contrarily the pressure decreases while the flow increases in the inspiratory phase during the apnea state both the pressure and the flow remain unchanged. According to the above variation characteristics of breath a feedback-based method for creating bi-level positive airway pressure is proposed. Experiments are implemented to verify the BiPAP model. Results demonstrate that the proposed method works effectively in following respiration and caters well to most polypnea and apnea events.展开更多
A pilot pattern across two orthogonal frequency division multiplexing OFDM symbols with a special structure is designed for the channel estimation of OFDM systems with inphase and quadrature IQ imbalances at the recei...A pilot pattern across two orthogonal frequency division multiplexing OFDM symbols with a special structure is designed for the channel estimation of OFDM systems with inphase and quadrature IQ imbalances at the receiver.A high-efficiency time-domain TD least square LS channel estimator and a low-complexity frequency-domain Gaussian elimination GE equalizer are proposed to eliminate IQ distortion.The former estimator can significantly suppress channel noise by a factor N/L+1 over the existing frequency-domain FD LS where N and L+1 are the total number of subcarriers and the length of cyclic prefix and the proposed GE requires only 2N complex multiplications per OFDM symbol.Simulation results show that by exploiting the TD property of the channel the proposed TD-LS channel estimator obtains a significant signal-to-noise ratio gain over the existing FD-LS one whereas the proposed low-complexity GE compensation achieves the same bit error rate BER performance as the existing LS one.展开更多
The analyses of a data series obtained during TOGA- COARE show the existence of remarkable semi-diurnal intemal tides in the western equatorial Pacific Ocean around 1°45'S, 156°E. Some characteristic parame...The analyses of a data series obtained during TOGA- COARE show the existence of remarkable semi-diurnal intemal tides in the western equatorial Pacific Ocean around 1°45'S, 156°E. Some characteristic parameters of the internal tides are vertical wavenumber -1.6×10^-3 m^-1, horizontal wavenumber (wavelength) 3.3×10^-2 km^-1 (210 km), vertical propagation speed -3.8 cm/s and horizontal propagation speed 2.0 m/s. The waveforms propagate downwards slantingly, that is, the wave energy transfers upwards slantingly. Depth-distribution of the'rotary spectral levels is a saddle-shape. The depths of the trough and the deeper peaks are almost coincident with those of the south boundaries of the South Equatorial Current and the Equatorial Undercurrent, respectively. The mean orientation of the rotary spectral ellipse changes with depth: 30° from north to east at 40 m, and changes into 14° from east to south at 324 m, and generally, it points to northeastward, which indicates "that waves come from the southwest.展开更多
Annual Rossby wave is a key component of the ENSO phenomenon in the equatorial Pacific Ocean. Due to the paucity and seasonal bias in historical hydrographic data,previous studies on equatorial Rossby waves only gave ...Annual Rossby wave is a key component of the ENSO phenomenon in the equatorial Pacific Ocean. Due to the paucity and seasonal bias in historical hydrographic data,previous studies on equatorial Rossby waves only gave qualitative description. The accumulation of Argo measurements in recent years has greatly alleviated the data problem. In this study,seasonal variation of the equatorial Pacific Ocean is examined with annual harmonic analysis of Argo gridded data. Results show that strong seasonal signal is present in the western equatorial Pacific and explains more than 50% of the thermal variance below 500 m. Lag-correlation tracing further shows that this sub-thermocline seasonal signal originates from the eastern equatorial Pacific via downward and southwestward propagation of annual Rossby waves. Possible mechanisms for the equatorward shift of Rossby wave path are also discussed.展开更多
In view of the importance of gas-liquid two-phase spiral flow and the few research reports at home and abroad,the gas-liquid two-phase spiral flow patterns have been researched in a horizontal pipe with different para...In view of the importance of gas-liquid two-phase spiral flow and the few research reports at home and abroad,the gas-liquid two-phase spiral flow patterns have been researched in a horizontal pipe with different parameters investigated by means of observation and a high-speed camera.Since the appearance of spiral flow makes the distribution of twophase flow more complicated,the flow patterns appearing in the experiments were divided into the Spiral Wavy Stratified Flow(SWS),the Spiral Bubble Flow(SB),the Spiral Slug Flow(SS),the Spiral Linear Flow(SL),the Spiral Axial Flow(SA),and the Spiral Dispersed Flow(SD) by the observations and with reference to the predecessors' research achievements.A flow pattern map has been drawn up.The influence of velocity,vane angle and vane area on flow pattern conversion boundary and pressure drop has been studied,with a solid foundation laid for the future research work.展开更多
Lag correlations between sea surface temperature anomalies (SSTA) in the southeastern tropical Indian Ocean (STIO) in fall and Nifio 3.4 SSTA in the eastern equatorial Pacific in the following fall are subjected t...Lag correlations between sea surface temperature anomalies (SSTA) in the southeastern tropical Indian Ocean (STIO) in fall and Nifio 3.4 SSTA in the eastern equatorial Pacific in the following fall are subjected to decadal variation, with positive correlations during some decades and negative correlations during others. Negative correlations are smaller and of shorter duration than positive correlations. Variations in lag correlations suggest that the use of the Indian Ocean Dipole (IOD) as a predictor of the E1 Nifio- Southern Oscillation (ENSO) at a lead time of one year is not effective during some decades. In this study, lag correlations between IOD and ENSO anomalies were analyzed to investigate why the IOD-ENSO teleconnection disappears during decades with negative correlations. Anomalies induced by the IOD in the equatorial Pacific Ocean during decades with negative correlations are still present, but at a greater depth than in decades with positive correlations, resulting in a lack of response to oceanic channel dynamics in the cold tongue SSTA. Lag correlations between oceanic anomalies in the west Pacific warm pool in fall and the equatorial Pacific cold tongue with a one-year time lag are significantly positive during decades with negative correlations. These results suggest that oceanic channel dynamics are overwhelmed by ocean- atmosphere coupling over the equatorial Pacific Ocean during decades with negative correlations. Therefore, the Indonesian throughflow is not effective as a link between IOD signals and the equatorial Pacific ENSO.展开更多
AIM: To evaluate the ultrasonog raphy (EUS) features of gastric gastrointestinal stromal tumors (GISTs) as compared with gastric leiomyomas and then to determine the EUS features that could predict malignant GISTs.MET...AIM: To evaluate the ultrasonog raphy (EUS) features of gastric gastrointestinal stromal tumors (GISTs) as compared with gastric leiomyomas and then to determine the EUS features that could predict malignant GISTs.METHODS: We evaluated the endoscopic EUS features in 53 patients with gastric mesenchymal tumors conf irmed by histopathologic diagnosis. The GISTs were classif ied into benign and malignant groups according to the histological risk classif ication.RESULTS: Immunohistochemical analyses demon-strated 7 leiomyomas and 46 GISTs. Inhomogenicity, hyperechogenic spots, a marginal halo and higher echogenicity as compared with the surrounding muscle layer appeared more frequently in the GISTs than in the leiomyomas (P < 0.05). The presence of at least two of these four features had a sensitivity of 89.1% and a specifi city of 85.7% for predicting GISTs. Except for tumor size and irregularity of the border, most of the EUS features were not helpful for predicting the malignant potential of GISTs. On multivariate analysis, only the maximal diameter of the GISTs was an independent predictor. The optimal size for predicting malignant GISTs was 35 mm. The sensitivity and specificity using this value were 92.3% and 78.8%, respectively.CONCLUSION: EUS may help to differentiate gastric GISTs from gastric leiomyomas. Once GISTs are suspected, surgery should be considered if the size is greater than 3.5 cm.展开更多
\ The effects of tetrandrine (Tet) on cytosolic free calcium ([Ca2+]i) in subcultured bovine aortic smooth muscle cells (SMC) were studied by Fura2 and ARCMMIC cation measurement system. Tet (1~100 μmol·L-1) ...\ The effects of tetrandrine (Tet) on cytosolic free calcium ([Ca2+]i) in subcultured bovine aortic smooth muscle cells (SMC) were studied by Fura2 and ARCMMIC cation measurement system. Tet (1~100 μmol·L-1) had no effect on the resting [Ca2+]i, but had inhibitory effects on [Ca2+]i elevation induced by high K+, 5HT, ATP, Ang II and NE in the presence of extracellular Ca2+. High concentration of Tet also inhibited Pheinduced [Ca2+]i elevation in absence of extracellular Ca2+. Tet (1~100 μmol·L-1) inhibited KCl (60 mmol·L-1) induced [Ca2+]i elevation in dosedependent manner, the IC50 value was 9.2 (95% confidence limits: 5.7~14.9) mmol·L-1. The results suggested that Tet had blocking effects on both VOC and ROC in bovine aortic SMC. It appears that the mechanisms of blocking effect of Tet on ROC might be primarily due to its Ca2+ entry blocking effects.展开更多
Based on the Zebiak-Cane model, the timedependent nonlinear forcing singular vector (NFSV)-type tendency errors with components of 4 and 12 (denoted by NFSV-4 and NFSV-12) are calculated for predetermined El Nifio...Based on the Zebiak-Cane model, the timedependent nonlinear forcing singular vector (NFSV)-type tendency errors with components of 4 and 12 (denoted by NFSV-4 and NFSV-12) are calculated for predetermined El Nifio events and compared with the constant NFSV (denoted by NFSV-1) from their patterns and resultant prediction errors. Specifically, NFSV-1 has a zonal dipolar sea surface temperature anomaly (SSTA) pattern with negative anomalies in the equatorial eastern Pacific and positive anomalies in the equatorial central-western Pa- cific. Although the first few components in NFSV-4 and NFSV-12 present patterns similar to NFSV-1, they tend to extend their dipoles farther westward; meanwhile, the positive anomalies gradually cover much smaller regions with the lag times. In addition, the authors calculate the predic- tion errors caused by the three kinds of NFSVs, and the results indicate that the prediction error induced by NFSV-12 is the largest, followed by the NFSV-4. However, when compared with the prediction errors caused by random tendency errors, the NFSVs generate significantly larger prediction errors. It is therefore shown that the spatial structure of tendency errors is important for producing large prediction errors. Furthermore, in exploring the tendency errors that cause the largest prediction error for E1 Nifio events, the timedependent NFSV should be evaluated.展开更多
The sunny-shady slopes effect is a phenomenon that impacts the temperature distribution of high-speed railway subgrades,resulting in uneven frost heaving deformation on the subgrade surface,which in turn causes static...The sunny-shady slopes effect is a phenomenon that impacts the temperature distribution of high-speed railway subgrades,resulting in uneven frost heaving deformation on the subgrade surface,which in turn causes static irregularity in the slab track.Based on the hydraulics theory,a thermal-hydro-mechanical(THM)coupled model of frozen soil is established and verified.We explore the process and characteristics of the temperature field and deformation of soil during the freezing process of high-speed railway subgrades and analyze the track irregularity variation law of China Railway Track SystemⅢslab tracks under uneven frost heaving deformation.The results show that,because the left and right slopes of high-speed railway subgrade are exposed to different amounts of solar radiation,which is the key factor causing uneven frost heaving of subgrade.Different strike angles cause changes in temperature of the subgrade’s upper part and the frost heaving amount on the surface,leading to differences in the deformation of the slab track structure:Increased strike angle weakens the rail level irregularity of the down line and marginally increases the rail level irregularity of the up line,and these become consistent in north-south directions.Therefore,when selecting railway lines in seasonal frozen areas,the west-east direction should be avoided to prevent the extremes in sunny-shady slopes effect on subgrades.展开更多
The characteristics of a new type of drainage channel with staggered indented sills for controlling debris flows were studied. The intermediate fluid in the non-viscous debris flow exhibited a helical movement, wherea...The characteristics of a new type of drainage channel with staggered indented sills for controlling debris flows were studied. The intermediate fluid in the non-viscous debris flow exhibited a helical movement, whereas the fluid near the sidewall had a stop-start movement pattern; the viscous debris flow exhibited a stable structure between the indented sills. The experimental results indicate that the mean velocity of the debris flow increased with increasing channel gradients, and the debris flow velocity was slightly affected by the angle of the sills. The average velocity of the non-viscous debris flow increased in the range of(0.5–1.5) interval between the indented sills, whereas the average velocity of the viscous debris flow increased initially and then decreased in the range of(0.75–1.25) interval between the indented sills. The depth of the non-viscous debris flow tended to gradually increase as the channel gradients increased, whereas the depth of the viscous debris flow gradually decreased as the channel gradients increased. When the discharge of the debris flow was constant, the angle and the interval between the indented sills had a slight effect on the depth of the viscous debris flow, whereas the depth of the non-viscous debris flow exhibited a different trend, as the sill angles and intervals were varied.展开更多
Suspended particulate substances were sampled in the eastem equatorial Pacific in water column from surface to near bottom in five stations in 2005, from which 868 barite crystals were recovered. The barite crystals w...Suspended particulate substances were sampled in the eastem equatorial Pacific in water column from surface to near bottom in five stations in 2005, from which 868 barite crystals were recovered. The barite crystals were examined under scanning electron microscopy. About 61% of the total barites crystals contained detectable Sr by energy dispersive X-ray spectrometry. Barite crystals could be classified into four groups based on their morphology: 1) bladed; 2) ovoid or rounded; 3) arrow-like; and 4) irregularly shaped. The arrow-like barite crystals in natural environment has never been reported before. In addition, about a half of the studied crystals showed features of dissolution as cavities or holes inside of the crystals or around their edges. We found that differential dissolution of barite crystals is consequence of heterogeneous Sr distribution in barite crystals. Our results would help in understanding the biogeochemical processes of marine barite formation and preservation in seawater and marine sediments.展开更多
In order to reveal the dynamic process of hard-thick roof inducing rock burst, one of the most common and strongest dynamic disasters in coal mine, the numerical simulation is conducted to study the dynamic loading ef...In order to reveal the dynamic process of hard-thick roof inducing rock burst, one of the most common and strongest dynamic disasters in coal mine, the numerical simulation is conducted to study the dynamic loading effect of roof vibration on roadway surrounding rocks as well as the impact on stability. The results show that, on one hand, hard-thick roof will result in high stress concentration on mining surrounding rocks; on the other hand, the breaking of hard-thick roof will lead to mining seismicity, causing dynamic loading effect on coal and rock mass. High stress concentration and dynamic loading combination reaches to the mechanical conditions for the occurrence of rock burst, which will induce rock burst. The mining induced seismic events occurring in the roof breaking act on the mining surrounding rocks in the form of stress wave. The stress wave then has a reflection on the free surface of roadway and the tensile stress will be generated around the free surface. Horizontal vibration of roadway surrounding particles will cause instant changes of horizontal stress of roadway surrounding rocks; the horizontal displacement is directly related to the horizontal stress but is not significantly correlated with the vertical stress; the increase of horizontal stress of roadway near surface surrounding rocks and the release of elastic deformation energy of deep surrounding coal and rock mass are immanent causes that lead to the impact instability of roadway surrounding rocks. The most significant measures for rock burst prevention are controlling of horizontal stress and vibration strength.Key words展开更多
基金supported by National Natural Science Foundation of China(Nos.51476073,51266004)Natural Science Foundation of Gansu Province(No.138RJZA199).
文摘With the rapid development of urban rail transit,there have been an urgent problem of excessive stray current.Because the stray current distribution is random and difficult to verify in the field,we designed an improved stray current experimental platform by replacing the simulated aqueous solution with a real soil environment and by calculating the transition resistance by measuring the soil resistivity,which makes up for the defects in the previous references.Firstly,the mathematical models of rail-drainage net and rail-drainage netground were established,and the analytical expressions of current and voltage of rail,drainage net and other structures were derived.In addition,the simulation model was built,and the mathematical analysis results were compared with the simulation results.Secondly,the accuracy of the improved stray current experimental platform was verified by comparing the measured and simulation results.Finally,based on the experimental results,the influence factors of stray current were analyzed.The relevant conclusions provide experimental data and theoretical reference for the study of stray current in urban rail transit.
基金The National Natural Science Foundation of China(No.51275090)the Science and Technology Support Program of Jiangsu Province(No.BE2011608)the Program for Special Talent in Six Fields of Jiangsu Province(No.2008144)
文摘An airway pressure and flow data acquisition system is developed to investigate the approach to building the bi-level positive airway pressure BiPAP in a ventilator.A number of experiments under different breathing situations and states are conducted and the experimental data are recorded.According to the data from these experiments the variation characteristics of the pressure and flow are analyzed using Matlab. The data analysis results show that the pressure increases while the flow decreases in the expiratory phase contrarily the pressure decreases while the flow increases in the inspiratory phase during the apnea state both the pressure and the flow remain unchanged. According to the above variation characteristics of breath a feedback-based method for creating bi-level positive airway pressure is proposed. Experiments are implemented to verify the BiPAP model. Results demonstrate that the proposed method works effectively in following respiration and caters well to most polypnea and apnea events.
基金The Open Research Fund of National Mobile Communications Research Laboratory of Southeast University(No.2013D02)the Fundamental Research Funds for the Central Universities(No.30920130122004)the National Natural Science Foundation of China(No.61271230,61472190)
文摘A pilot pattern across two orthogonal frequency division multiplexing OFDM symbols with a special structure is designed for the channel estimation of OFDM systems with inphase and quadrature IQ imbalances at the receiver.A high-efficiency time-domain TD least square LS channel estimator and a low-complexity frequency-domain Gaussian elimination GE equalizer are proposed to eliminate IQ distortion.The former estimator can significantly suppress channel noise by a factor N/L+1 over the existing frequency-domain FD LS where N and L+1 are the total number of subcarriers and the length of cyclic prefix and the proposed GE requires only 2N complex multiplications per OFDM symbol.Simulation results show that by exploiting the TD property of the channel the proposed TD-LS channel estimator obtains a significant signal-to-noise ratio gain over the existing FD-LS one whereas the proposed low-complexity GE compensation achieves the same bit error rate BER performance as the existing LS one.
基金This paper is supported by the National Natural Science Foundation of China(Projects under contracts No.49676275,49976002,40506007)Microwave Imaging National Key Laboratory Foundation(No.51442020103JW1002).
文摘The analyses of a data series obtained during TOGA- COARE show the existence of remarkable semi-diurnal intemal tides in the western equatorial Pacific Ocean around 1°45'S, 156°E. Some characteristic parameters of the internal tides are vertical wavenumber -1.6×10^-3 m^-1, horizontal wavenumber (wavelength) 3.3×10^-2 km^-1 (210 km), vertical propagation speed -3.8 cm/s and horizontal propagation speed 2.0 m/s. The waveforms propagate downwards slantingly, that is, the wave energy transfers upwards slantingly. Depth-distribution of the'rotary spectral levels is a saddle-shape. The depths of the trough and the deeper peaks are almost coincident with those of the south boundaries of the South Equatorial Current and the Equatorial Undercurrent, respectively. The mean orientation of the rotary spectral ellipse changes with depth: 30° from north to east at 40 m, and changes into 14° from east to south at 324 m, and generally, it points to northeastward, which indicates "that waves come from the southwest.
基金Supported by the National Basic Research Program of China(973 Program)(No.2012CB417400)the National Natural Science Foundation of China(Nos.41421005,U1406401)
文摘Annual Rossby wave is a key component of the ENSO phenomenon in the equatorial Pacific Ocean. Due to the paucity and seasonal bias in historical hydrographic data,previous studies on equatorial Rossby waves only gave qualitative description. The accumulation of Argo measurements in recent years has greatly alleviated the data problem. In this study,seasonal variation of the equatorial Pacific Ocean is examined with annual harmonic analysis of Argo gridded data. Results show that strong seasonal signal is present in the western equatorial Pacific and explains more than 50% of the thermal variance below 500 m. Lag-correlation tracing further shows that this sub-thermocline seasonal signal originates from the eastern equatorial Pacific via downward and southwestward propagation of annual Rossby waves. Possible mechanisms for the equatorward shift of Rossby wave path are also discussed.
基金supported by the National Natural Science Foundation of China (Grant number 51776015)
文摘In view of the importance of gas-liquid two-phase spiral flow and the few research reports at home and abroad,the gas-liquid two-phase spiral flow patterns have been researched in a horizontal pipe with different parameters investigated by means of observation and a high-speed camera.Since the appearance of spiral flow makes the distribution of twophase flow more complicated,the flow patterns appearing in the experiments were divided into the Spiral Wavy Stratified Flow(SWS),the Spiral Bubble Flow(SB),the Spiral Slug Flow(SS),the Spiral Linear Flow(SL),the Spiral Axial Flow(SA),and the Spiral Dispersed Flow(SD) by the observations and with reference to the predecessors' research achievements.A flow pattern map has been drawn up.The influence of velocity,vane angle and vane area on flow pattern conversion boundary and pressure drop has been studied,with a solid foundation laid for the future research work.
基金Supported by the National Basic Research Program of China(973 Program)(Nos.2012CB956000,2011CB403502)the National Natural Science Foundation of China(No.41176019)+1 种基金the China Meteorological Administration(No.GYHY201306018)the Strategic Priority Program of Chinese Academy of Sciences(No.XDA11010301)
文摘Lag correlations between sea surface temperature anomalies (SSTA) in the southeastern tropical Indian Ocean (STIO) in fall and Nifio 3.4 SSTA in the eastern equatorial Pacific in the following fall are subjected to decadal variation, with positive correlations during some decades and negative correlations during others. Negative correlations are smaller and of shorter duration than positive correlations. Variations in lag correlations suggest that the use of the Indian Ocean Dipole (IOD) as a predictor of the E1 Nifio- Southern Oscillation (ENSO) at a lead time of one year is not effective during some decades. In this study, lag correlations between IOD and ENSO anomalies were analyzed to investigate why the IOD-ENSO teleconnection disappears during decades with negative correlations. Anomalies induced by the IOD in the equatorial Pacific Ocean during decades with negative correlations are still present, but at a greater depth than in decades with positive correlations, resulting in a lack of response to oceanic channel dynamics in the cold tongue SSTA. Lag correlations between oceanic anomalies in the west Pacific warm pool in fall and the equatorial Pacific cold tongue with a one-year time lag are significantly positive during decades with negative correlations. These results suggest that oceanic channel dynamics are overwhelmed by ocean- atmosphere coupling over the equatorial Pacific Ocean during decades with negative correlations. Therefore, the Indonesian throughflow is not effective as a link between IOD signals and the equatorial Pacific ENSO.
基金Supported by A Medical Research Institute Grant (2008-1)Pusan National University and a grant from the National R&D Program for Cancer Control, Ministry for Health, Welfare and Family affairs, Republic of Korea (0920050)
文摘AIM: To evaluate the ultrasonog raphy (EUS) features of gastric gastrointestinal stromal tumors (GISTs) as compared with gastric leiomyomas and then to determine the EUS features that could predict malignant GISTs.METHODS: We evaluated the endoscopic EUS features in 53 patients with gastric mesenchymal tumors conf irmed by histopathologic diagnosis. The GISTs were classif ied into benign and malignant groups according to the histological risk classif ication.RESULTS: Immunohistochemical analyses demon-strated 7 leiomyomas and 46 GISTs. Inhomogenicity, hyperechogenic spots, a marginal halo and higher echogenicity as compared with the surrounding muscle layer appeared more frequently in the GISTs than in the leiomyomas (P < 0.05). The presence of at least two of these four features had a sensitivity of 89.1% and a specifi city of 85.7% for predicting GISTs. Except for tumor size and irregularity of the border, most of the EUS features were not helpful for predicting the malignant potential of GISTs. On multivariate analysis, only the maximal diameter of the GISTs was an independent predictor. The optimal size for predicting malignant GISTs was 35 mm. The sensitivity and specificity using this value were 92.3% and 78.8%, respectively.CONCLUSION: EUS may help to differentiate gastric GISTs from gastric leiomyomas. Once GISTs are suspected, surgery should be considered if the size is greater than 3.5 cm.
文摘\ The effects of tetrandrine (Tet) on cytosolic free calcium ([Ca2+]i) in subcultured bovine aortic smooth muscle cells (SMC) were studied by Fura2 and ARCMMIC cation measurement system. Tet (1~100 μmol·L-1) had no effect on the resting [Ca2+]i, but had inhibitory effects on [Ca2+]i elevation induced by high K+, 5HT, ATP, Ang II and NE in the presence of extracellular Ca2+. High concentration of Tet also inhibited Pheinduced [Ca2+]i elevation in absence of extracellular Ca2+. Tet (1~100 μmol·L-1) inhibited KCl (60 mmol·L-1) induced [Ca2+]i elevation in dosedependent manner, the IC50 value was 9.2 (95% confidence limits: 5.7~14.9) mmol·L-1. The results suggested that Tet had blocking effects on both VOC and ROC in bovine aortic SMC. It appears that the mechanisms of blocking effect of Tet on ROC might be primarily due to its Ca2+ entry blocking effects.
基金sponsored by the National Basic Research Program of China (Grant No. 2012CB955202)the National Public Benefit (Meteorology) Research Foundation of China (Grant No. GYHY201306018)the National Natural Science Foundation of China (Grant Nos. 41176013 and 41230420)
文摘Based on the Zebiak-Cane model, the timedependent nonlinear forcing singular vector (NFSV)-type tendency errors with components of 4 and 12 (denoted by NFSV-4 and NFSV-12) are calculated for predetermined El Nifio events and compared with the constant NFSV (denoted by NFSV-1) from their patterns and resultant prediction errors. Specifically, NFSV-1 has a zonal dipolar sea surface temperature anomaly (SSTA) pattern with negative anomalies in the equatorial eastern Pacific and positive anomalies in the equatorial central-western Pa- cific. Although the first few components in NFSV-4 and NFSV-12 present patterns similar to NFSV-1, they tend to extend their dipoles farther westward; meanwhile, the positive anomalies gradually cover much smaller regions with the lag times. In addition, the authors calculate the predic- tion errors caused by the three kinds of NFSVs, and the results indicate that the prediction error induced by NFSV-12 is the largest, followed by the NFSV-4. However, when compared with the prediction errors caused by random tendency errors, the NFSVs generate significantly larger prediction errors. It is therefore shown that the spatial structure of tendency errors is important for producing large prediction errors. Furthermore, in exploring the tendency errors that cause the largest prediction error for E1 Nifio events, the timedependent NFSV should be evaluated.
基金Projects(2021YFF0502100,2021YFB2600900)supported by the National Key R&D Program of ChinaProjects(52022085,52278461)supported by the National Natural Science Foundation of ChinaProject(22CXTD0051)supported by Sichuan Youth Science and Technology Innovation Team,China。
文摘The sunny-shady slopes effect is a phenomenon that impacts the temperature distribution of high-speed railway subgrades,resulting in uneven frost heaving deformation on the subgrade surface,which in turn causes static irregularity in the slab track.Based on the hydraulics theory,a thermal-hydro-mechanical(THM)coupled model of frozen soil is established and verified.We explore the process and characteristics of the temperature field and deformation of soil during the freezing process of high-speed railway subgrades and analyze the track irregularity variation law of China Railway Track SystemⅢslab tracks under uneven frost heaving deformation.The results show that,because the left and right slopes of high-speed railway subgrade are exposed to different amounts of solar radiation,which is the key factor causing uneven frost heaving of subgrade.Different strike angles cause changes in temperature of the subgrade’s upper part and the frost heaving amount on the surface,leading to differences in the deformation of the slab track structure:Increased strike angle weakens the rail level irregularity of the down line and marginally increases the rail level irregularity of the up line,and these become consistent in north-south directions.Therefore,when selecting railway lines in seasonal frozen areas,the west-east direction should be avoided to prevent the extremes in sunny-shady slopes effect on subgrades.
基金sponsored by the Key Deployment Project of Chinese Academy of Sciences(Grant No.KZZD-EW-05-01)the National Science Foundation of China(Grant No.41072270)
文摘The characteristics of a new type of drainage channel with staggered indented sills for controlling debris flows were studied. The intermediate fluid in the non-viscous debris flow exhibited a helical movement, whereas the fluid near the sidewall had a stop-start movement pattern; the viscous debris flow exhibited a stable structure between the indented sills. The experimental results indicate that the mean velocity of the debris flow increased with increasing channel gradients, and the debris flow velocity was slightly affected by the angle of the sills. The average velocity of the non-viscous debris flow increased in the range of(0.5–1.5) interval between the indented sills, whereas the average velocity of the viscous debris flow increased initially and then decreased in the range of(0.75–1.25) interval between the indented sills. The depth of the non-viscous debris flow tended to gradually increase as the channel gradients increased, whereas the depth of the viscous debris flow gradually decreased as the channel gradients increased. When the discharge of the debris flow was constant, the angle and the interval between the indented sills had a slight effect on the depth of the viscous debris flow, whereas the depth of the non-viscous debris flow exhibited a different trend, as the sill angles and intervals were varied.
基金Supported by the China Ocean Mineral Resources R&D Association(Mas,DYXM-115-02-1-13,DYXM-115-01-3-04)
文摘Suspended particulate substances were sampled in the eastem equatorial Pacific in water column from surface to near bottom in five stations in 2005, from which 868 barite crystals were recovered. The barite crystals were examined under scanning electron microscopy. About 61% of the total barites crystals contained detectable Sr by energy dispersive X-ray spectrometry. Barite crystals could be classified into four groups based on their morphology: 1) bladed; 2) ovoid or rounded; 3) arrow-like; and 4) irregularly shaped. The arrow-like barite crystals in natural environment has never been reported before. In addition, about a half of the studied crystals showed features of dissolution as cavities or holes inside of the crystals or around their edges. We found that differential dissolution of barite crystals is consequence of heterogeneous Sr distribution in barite crystals. Our results would help in understanding the biogeochemical processes of marine barite formation and preservation in seawater and marine sediments.
基金Project(51404243)supported by the National Natural Science Foundation of ChinaProject(2014QNB26)supported by the Fundamental Research Funds for the Central Universities,China
文摘In order to reveal the dynamic process of hard-thick roof inducing rock burst, one of the most common and strongest dynamic disasters in coal mine, the numerical simulation is conducted to study the dynamic loading effect of roof vibration on roadway surrounding rocks as well as the impact on stability. The results show that, on one hand, hard-thick roof will result in high stress concentration on mining surrounding rocks; on the other hand, the breaking of hard-thick roof will lead to mining seismicity, causing dynamic loading effect on coal and rock mass. High stress concentration and dynamic loading combination reaches to the mechanical conditions for the occurrence of rock burst, which will induce rock burst. The mining induced seismic events occurring in the roof breaking act on the mining surrounding rocks in the form of stress wave. The stress wave then has a reflection on the free surface of roadway and the tensile stress will be generated around the free surface. Horizontal vibration of roadway surrounding particles will cause instant changes of horizontal stress of roadway surrounding rocks; the horizontal displacement is directly related to the horizontal stress but is not significantly correlated with the vertical stress; the increase of horizontal stress of roadway near surface surrounding rocks and the release of elastic deformation energy of deep surrounding coal and rock mass are immanent causes that lead to the impact instability of roadway surrounding rocks. The most significant measures for rock burst prevention are controlling of horizontal stress and vibration strength.Key words