A mutant (GQQ-M6) of a Sponge-Derived streptomyces sp. GQQ-10 obtained by UV-induced mutation was used for producing prodiginines (PGs). Single factor experiments and orthogonal array design (OAD) methods were employe...A mutant (GQQ-M6) of a Sponge-Derived streptomyces sp. GQQ-10 obtained by UV-induced mutation was used for producing prodiginines (PGs). Single factor experiments and orthogonal array design (OAD) methods were employed for medium optimization. In the single factor method, the effects of soluble starch, glucose, soybean flour, yeast extract and sodium acetate on PGs production were investigated individually. In the subsequent OAD experiments, the concentrations of these 5 key nutritional components combined with salinity were further adjusted. The mutant strain GQQ-M6 gave a 2.2-fold higher PGs production than that of the parent strain; OAD experiments offered a PGs yield of 61mg L-1, which was 10 times higher than that of the initial GQQ-10 strain under the original cultivation mode.展开更多
Efficient data visualization techniques are critical for many scientific applications. Centroidal Voronoi tessellation(CVT) based algorithms offer a convenient vehicle for performing image analysis,segmentation and co...Efficient data visualization techniques are critical for many scientific applications. Centroidal Voronoi tessellation(CVT) based algorithms offer a convenient vehicle for performing image analysis,segmentation and compression while allowing to optimize retained image quality with respect to a given metric.In experimental science with data counts following Poisson distributions,several CVT-based data tessellation algorithms have been recently developed.Although they surpass their predecessors in robustness and quality of reconstructed data,time consumption remains to be an issue due to heavy utilization of the slowly converging Lloyd iteration.This paper discusses one possible approach to accelerating data visualization algorithms.It relies on a multidimensional generalization of the optimization based multilevel algorithm for the numerical computation of the CVTs introduced in[1],where a rigorous proof of its uniform convergence has been presented in 1-dimensional setting.The multidimensional implementation employs barycentric coordinate based interpolation and maximal independent set coarsening procedures.It is shown that when coupled with bin accretion algorithm accounting for the discrete nature of the data,the algorithm outperforms Lloyd-based schemes and preserves uniform convergence with respect to the problem size.Although numerical demonstrations provided are limited to spectroscopy data analysis,the method has a context-independent setup and can potentially deliver significant speedup to other scientific and engineering applications.展开更多
Along with the economic development,large tunnels need to be constructed in many high mountains or complex structure regions,and the design and construction of detailed tunnel exploration become particularly important...Along with the economic development,large tunnels need to be constructed in many high mountains or complex structure regions,and the design and construction of detailed tunnel exploration become particularly important.Transient electromagnetic method( TEM) uses a non-grounded loop or an electrode to send a primary electromagnetic pulse into the ground,and observes spatial and temporal distribution of secondary electromagnetic field,which is widely applied in mineral resource exploration,engineering geology,etc.The application of TEM in the tunnel construction of Kaiyuan Temple is researched in this study.The smoke loop inversion is adopted for inverting the transient electromagnetic data.The drilling data and high density resistivity method data are combined for comparison.The obtained inversion result greatly coincides with the actual conditions.Therefore,the geophysical prospecting basis can be provided for the division of stratum,delineation of geological structure,and design and construction of tunnel pavement.By virtue of TEM,drilling data and high density resistivity method,the tunnel construction of Kaiyuan Temple has obtained satisfactory results.展开更多
Objective： To review literature from 1956 to 2007 and explore regularities in points selection and methods for acupuncture-moxibustion treatment of allergic rhinitis. Methods： A comprehensive analysis was made by a ...Objective： To review literature from 1956 to 2007 and explore regularities in points selection and methods for acupuncture-moxibustion treatment of allergic rhinitis. Methods： A comprehensive analysis was made by a method of metrological analysis according to the data from ＂China Modem Acupuncture-moxibustion Information Databank＂. Results： Points Yingxiang （LI 20） and Feishu （BL 13） were most frequently used. Acupuncture and hydro-acupuncture were the major treatment methods. Conclusion： It is suggested that Yingxiang （LI 20）, Yintang （Ex-HN 3）, Feishu （BL 13） and Dazhui （GV 14） be used as a basic prescription for acupuncture-moxibustion treatment of allergic rhinitis, which is combined with point selection based on syndrome differentiation.展开更多
The theoretical design method of enhanced sensitivity fiber grating （FBG） strain sensors was given, and moreover high qualified strain sensors were developed and fabricated, whose sensing properties were good for pr...The theoretical design method of enhanced sensitivity fiber grating （FBG） strain sensors was given, and moreover high qualified strain sensors were developed and fabricated, whose sensing properties were good for practical applications. The strain sensor with cylindrical shell encapsulation contained three tubular structures, due to the uneven surface structure, in the area of the strain concentration, improving the sensitivity. It could achieve the embedment strain measurement and surface measurement and had the advantages of the easy installation. The good agreement was obtained between the measurements and theoretical simulation results. After each calibration test, twenty-four FBG strain sensors and six FBG temperature compensation sensors have been installed on the undersurface of the box girder of Diaoshuiyan bridge in Yongtaiwen highway. Finally, we built up a long-term structure health system for the highway bridge.展开更多
基金supported by the National Natural Science Foundation of China (Nos.30973627 and 30772640)the public projects of the State Oceanic Administration (No.2010418022-3)+1 种基金the Program for Changjiang Scholars and Innovative Research Team in University (No.IRT0944)the Natural Science Fund of Shandong Province,P.R.China (No.ZR2009CZ016)
文摘A mutant (GQQ-M6) of a Sponge-Derived streptomyces sp. GQQ-10 obtained by UV-induced mutation was used for producing prodiginines (PGs). Single factor experiments and orthogonal array design (OAD) methods were employed for medium optimization. In the single factor method, the effects of soluble starch, glucose, soybean flour, yeast extract and sodium acetate on PGs production were investigated individually. In the subsequent OAD experiments, the concentrations of these 5 key nutritional components combined with salinity were further adjusted. The mutant strain GQQ-M6 gave a 2.2-fold higher PGs production than that of the parent strain; OAD experiments offered a PGs yield of 61mg L-1, which was 10 times higher than that of the initial GQQ-10 strain under the original cultivation mode.
基金supported by the grants DMS 0405343 and DMR 0520425.
文摘Efficient data visualization techniques are critical for many scientific applications. Centroidal Voronoi tessellation(CVT) based algorithms offer a convenient vehicle for performing image analysis,segmentation and compression while allowing to optimize retained image quality with respect to a given metric.In experimental science with data counts following Poisson distributions,several CVT-based data tessellation algorithms have been recently developed.Although they surpass their predecessors in robustness and quality of reconstructed data,time consumption remains to be an issue due to heavy utilization of the slowly converging Lloyd iteration.This paper discusses one possible approach to accelerating data visualization algorithms.It relies on a multidimensional generalization of the optimization based multilevel algorithm for the numerical computation of the CVTs introduced in[1],where a rigorous proof of its uniform convergence has been presented in 1-dimensional setting.The multidimensional implementation employs barycentric coordinate based interpolation and maximal independent set coarsening procedures.It is shown that when coupled with bin accretion algorithm accounting for the discrete nature of the data,the algorithm outperforms Lloyd-based schemes and preserves uniform convergence with respect to the problem size.Although numerical demonstrations provided are limited to spectroscopy data analysis,the method has a context-independent setup and can potentially deliver significant speedup to other scientific and engineering applications.
文摘Along with the economic development,large tunnels need to be constructed in many high mountains or complex structure regions,and the design and construction of detailed tunnel exploration become particularly important.Transient electromagnetic method( TEM) uses a non-grounded loop or an electrode to send a primary electromagnetic pulse into the ground,and observes spatial and temporal distribution of secondary electromagnetic field,which is widely applied in mineral resource exploration,engineering geology,etc.The application of TEM in the tunnel construction of Kaiyuan Temple is researched in this study.The smoke loop inversion is adopted for inverting the transient electromagnetic data.The drilling data and high density resistivity method data are combined for comparison.The obtained inversion result greatly coincides with the actual conditions.Therefore,the geophysical prospecting basis can be provided for the division of stratum,delineation of geological structure,and design and construction of tunnel pavement.By virtue of TEM,drilling data and high density resistivity method,the tunnel construction of Kaiyuan Temple has obtained satisfactory results.
文摘Objective： To review literature from 1956 to 2007 and explore regularities in points selection and methods for acupuncture-moxibustion treatment of allergic rhinitis. Methods： A comprehensive analysis was made by a method of metrological analysis according to the data from ＂China Modem Acupuncture-moxibustion Information Databank＂. Results： Points Yingxiang （LI 20） and Feishu （BL 13） were most frequently used. Acupuncture and hydro-acupuncture were the major treatment methods. Conclusion： It is suggested that Yingxiang （LI 20）, Yintang （Ex-HN 3）, Feishu （BL 13） and Dazhui （GV 14） be used as a basic prescription for acupuncture-moxibustion treatment of allergic rhinitis, which is combined with point selection based on syndrome differentiation.
文摘The theoretical design method of enhanced sensitivity fiber grating （FBG） strain sensors was given, and moreover high qualified strain sensors were developed and fabricated, whose sensing properties were good for practical applications. The strain sensor with cylindrical shell encapsulation contained three tubular structures, due to the uneven surface structure, in the area of the strain concentration, improving the sensitivity. It could achieve the embedment strain measurement and surface measurement and had the advantages of the easy installation. The good agreement was obtained between the measurements and theoretical simulation results. After each calibration test, twenty-four FBG strain sensors and six FBG temperature compensation sensors have been installed on the undersurface of the box girder of Diaoshuiyan bridge in Yongtaiwen highway. Finally, we built up a long-term structure health system for the highway bridge.
