This paper investigates the application of distributed optical fiber strain sensors to civil engineering structures, because no other tool can satisfactorily detect the location of the unpredictable phenomenon. In fac...This paper investigates the application of distributed optical fiber strain sensors to civil engineering structures, because no other tool can satisfactorily detect the location of the unpredictable phenomenon. In fact, the locations of cracks in the concrete structure are unknown a priori; therefore, a fully distributed sensor is necessary to detect them. The Brillouin optical correlation domain analysis （BOCDA）, which offers high spatial resolution by using stimulated Brillouin scattering along the whole length of the optical fiber, is used in a wide range of civil engineering applications, and the same has undergone significant development over the last decade. In this paper, it is demonstrated how a BOCDA-based strain sensor can be employed to monitor cracks in concrete. Crack monitoring on the surface of the concrete member provides useful information for evaluating stiffness and durability of the structure, particularly for early detection of tiny cracks, which is essential for preventing crack growth and dispersion. The crack-induced strain distribution was analytically investigated, and it was proved that BOCDA can identify even a small crack before its visual recognition by a beam test. Moreover, periodical crack monitoring was successfully executed on a pedestrian deck for five years.展开更多
Iodoacetic acid(IAA) has been applied to different species to acutely induce photoreceptor degeneration.The purpose of the present study was to use this toxin to thoroughly eliminate photoreceptors and induce complete...Iodoacetic acid(IAA) has been applied to different species to acutely induce photoreceptor degeneration.The purpose of the present study was to use this toxin to thoroughly eliminate photoreceptors and induce complete blindness in the cat.IAA was delivered by single ear vein injection(20 mgkg-1).Six months after the IAA treatment,functional evaluations including pupillary light reflex(PLR),electroretinogram(ERG),visual behavior tests were performed.Morphological examinations were carried out after the functional evaluation.The present result shows that,six months after the IAA application,animals lost visual functions and became completely blind.High dose IAA application via ear vein delivery created an acute and reliable complete photoreceptor degeneration model in the cat.This model can be applied to genetic and cellular therapies for visual function restoration.展开更多
文摘This paper investigates the application of distributed optical fiber strain sensors to civil engineering structures, because no other tool can satisfactorily detect the location of the unpredictable phenomenon. In fact, the locations of cracks in the concrete structure are unknown a priori; therefore, a fully distributed sensor is necessary to detect them. The Brillouin optical correlation domain analysis （BOCDA）, which offers high spatial resolution by using stimulated Brillouin scattering along the whole length of the optical fiber, is used in a wide range of civil engineering applications, and the same has undergone significant development over the last decade. In this paper, it is demonstrated how a BOCDA-based strain sensor can be employed to monitor cracks in concrete. Crack monitoring on the surface of the concrete member provides useful information for evaluating stiffness and durability of the structure, particularly for early detection of tiny cracks, which is essential for preventing crack growth and dispersion. The crack-induced strain distribution was analytically investigated, and it was proved that BOCDA can identify even a small crack before its visual recognition by a beam test. Moreover, periodical crack monitoring was successfully executed on a pedestrian deck for five years.
基金supported by National Basic Research Program of China(2009CB320900 and 2011CB510206 to Pu MingLiang,2011CB510200to Li XiaoXin)National Natural Science Foundation of China(30831160516 to Pu MingLiang)
文摘Iodoacetic acid(IAA) has been applied to different species to acutely induce photoreceptor degeneration.The purpose of the present study was to use this toxin to thoroughly eliminate photoreceptors and induce complete blindness in the cat.IAA was delivered by single ear vein injection(20 mgkg-1).Six months after the IAA treatment,functional evaluations including pupillary light reflex(PLR),electroretinogram(ERG),visual behavior tests were performed.Morphological examinations were carried out after the functional evaluation.The present result shows that,six months after the IAA application,animals lost visual functions and became completely blind.High dose IAA application via ear vein delivery created an acute and reliable complete photoreceptor degeneration model in the cat.This model can be applied to genetic and cellular therapies for visual function restoration.
