目的探讨原发性高血压病患者的经颅多普勒(T C D)及脑电图(EEG)特点。方法对124例原发性高血压病患者进行T C D及EEG检测,根据TC D和EEG的异常改变进行对比分析。结果TC D异常120例(96.7%),EEG异常28例(22.6%),且无特异性,但二者结合起...目的探讨原发性高血压病患者的经颅多普勒(T C D)及脑电图(EEG)特点。方法对124例原发性高血压病患者进行T C D及EEG检测,根据TC D和EEG的异常改变进行对比分析。结果TC D异常120例(96.7%),EEG异常28例(22.6%),且无特异性,但二者结合起来分析,对了解病变的严重程度有一定的价值。结论高血压病患者的T C D检测有较高的异常率。TC D检测有严重脑动脉硬化、脑血管重度痉挛或狭窄、脑供血明显不足的则EEG也表现为异常。因此,高血压病患者通过早期T C D和EEG检测,对临床的诊治和估计预后有一定的参考意义。展开更多
Objective. -Many studies have supported the hypothesis of alteration of cortical hyperexcitability as a possible pathological mechanism underlying the onset of migraine and epileptic attacks. Different biochemical pat...Objective. -Many studies have supported the hypothesis of alteration of cortical hyperexcitability as a possible pathological mechanism underlying the onset of migraine and epileptic attacks. Different biochemical pathways involving cellular structures may increase or decrease the excitability of neuronal membranes. The aim of this study was to identify a possible link between migraine and epilepsy from a clinical and neurophysiologic point of view. Methods. -One-hundred thirty-seven children and adolescents consecutively diagnosed for tensiontype headache and idiopathic migraine with and without aura were studied. Anamnestic, clinical, and instrumental data were collected by a neurological examination, a specific questionnaire, and awake electroencephalogram (EEG) registrations. EEG features of nonheadache and nonseizures control group were compared. Results. -Fourteen cases (10.2%) had a positive history for seizures with fever, isolated seizures, or epilepsy. Distribution differed according to headache diagnosis; migraine with aura (MWA) was largely prevalent. Specific electroencephalographic abnormalities were present in 11.7%of the sample, with a significant different distribution across the groups of children with headache and the control group: specific interictal abnormalities were found in 10 of 23 (43.5%) children with MWA. Two factors, seizures and specific interictal electroencephalographic abnormalities, showed a different distribution in patients with MWA compared to other classes of headache and control group (P≤.01). Conclusion. -The present study supports the hypothesis of a possible clinical continuum between some types of MWA and epileptic syndromes as entities due to altered neuronal excitability with similar genetic substrates.展开更多
文摘目的探讨原发性高血压病患者的经颅多普勒(T C D)及脑电图(EEG)特点。方法对124例原发性高血压病患者进行T C D及EEG检测,根据TC D和EEG的异常改变进行对比分析。结果TC D异常120例(96.7%),EEG异常28例(22.6%),且无特异性,但二者结合起来分析,对了解病变的严重程度有一定的价值。结论高血压病患者的T C D检测有较高的异常率。TC D检测有严重脑动脉硬化、脑血管重度痉挛或狭窄、脑供血明显不足的则EEG也表现为异常。因此,高血压病患者通过早期T C D和EEG检测,对临床的诊治和估计预后有一定的参考意义。
文摘Objective. -Many studies have supported the hypothesis of alteration of cortical hyperexcitability as a possible pathological mechanism underlying the onset of migraine and epileptic attacks. Different biochemical pathways involving cellular structures may increase or decrease the excitability of neuronal membranes. The aim of this study was to identify a possible link between migraine and epilepsy from a clinical and neurophysiologic point of view. Methods. -One-hundred thirty-seven children and adolescents consecutively diagnosed for tensiontype headache and idiopathic migraine with and without aura were studied. Anamnestic, clinical, and instrumental data were collected by a neurological examination, a specific questionnaire, and awake electroencephalogram (EEG) registrations. EEG features of nonheadache and nonseizures control group were compared. Results. -Fourteen cases (10.2%) had a positive history for seizures with fever, isolated seizures, or epilepsy. Distribution differed according to headache diagnosis; migraine with aura (MWA) was largely prevalent. Specific electroencephalographic abnormalities were present in 11.7%of the sample, with a significant different distribution across the groups of children with headache and the control group: specific interictal abnormalities were found in 10 of 23 (43.5%) children with MWA. Two factors, seizures and specific interictal electroencephalographic abnormalities, showed a different distribution in patients with MWA compared to other classes of headache and control group (P≤.01). Conclusion. -The present study supports the hypothesis of a possible clinical continuum between some types of MWA and epileptic syndromes as entities due to altered neuronal excitability with similar genetic substrates.