OBJECTIVE:The study aim was to use existing relevant indexes to establish an index series for the quantitative measurement of Qi deficiency pattern(QDP) in Traditional Chinese Medicine(TCM).METHODS:Seventeen indexes o...OBJECTIVE:The study aim was to use existing relevant indexes to establish an index series for the quantitative measurement of Qi deficiency pattern(QDP) in Traditional Chinese Medicine(TCM).METHODS:Seventeen indexes of arterial oxygen saturation(SaO_2),TCM pulse diagnosis,heart rate,and blood pressure were integrated into an index series,and 94 selected subjects were divided into a healthy control group,a mild QDP group,and a typical QDP group.All three groups were then synchronously given a breath-holding(BH) test and index detections using TCM apparatus for auxiliary diagnosis and treatment and a photoplethysmograph.The detections were carried out repeatedly until there was no monotonic change in the value of the minimal SaO_(2d)uring a BH measurement(SaO_(2 min)) or in the duration of BH during a BH measurement(TBH).RESULTS:BH measurement and index detection data from 380 eligible cases were analyzed and a significant intergroup difference was found for 12 indexes.CONCLUSION:An index series for quantitative QDP measurement could comprise the 12 effective indexes:RSaO_(2d)(rate of decline of SaO_(2d)uring a BH measurement),RSaO_(2r)(recovery rate of SaO_2 after a BH measurement),SaO_(2 min),BFV(blood flow velocity),TSaO_(2d)(the time at which SaO_2 started declining during a BH measurement),TBH,TSa_(O2 min)(the time of occurrence of the minimal SaO_(2d)uring a BH measurement),TSa O_(2 max)(the time of occurrence of the maximal SaO_2 after a BH measurement),PTP(pulse-touching pressure),SBP(systolic blood pressure),PWV(pulse wave velocity),and DBP(diastolic blood pressure).Of the indexes,RSaO_(2d)could play akey role in quantitative QDP measurement;RSaO_(2r) and Sa O_2 mincould be used to differentiate the QDP symptom of shortness of breath and as early-warning indexes for chronic obstructive pulmonary disease.BFV,TSaO_(2d),and TBHcould be used to quantitatively assess the QDP symptoms of spontaneous perspiration and shortness of breath.展开更多
基金National Natural Science Foundation-funded project:Construction of the Qi-Blood-Body Fluid Network Based on the Dynamic Detection of Human Biological Information and Research on the Network's Mechanism of Identification,a program funded by the of China(No.81473553)National Natural Science Foundation-funded project:Construction of TCM Qi-Function Biological Network Based on the Body Odor and Voice and Research on the Network's Mechanism(No.81573880)+1 种基金Science and Technology Assistance Project of the Ministry of Science and Technology of China to the Developing Countries:Sino-Mexican Cooperation Study on the Strategies for Hospice Care with the Intervention of Acupuncture and Moxibustion and the Related Clinical Research(No.KYZ201302010)Longitudinal scientific research development fund,Beijing University of Chinese Medicine:Key Technology of Photographic Identification for Meridian-Visceral Recuperation Device(No.2017-zxfzjj-024)
文摘OBJECTIVE:The study aim was to use existing relevant indexes to establish an index series for the quantitative measurement of Qi deficiency pattern(QDP) in Traditional Chinese Medicine(TCM).METHODS:Seventeen indexes of arterial oxygen saturation(SaO_2),TCM pulse diagnosis,heart rate,and blood pressure were integrated into an index series,and 94 selected subjects were divided into a healthy control group,a mild QDP group,and a typical QDP group.All three groups were then synchronously given a breath-holding(BH) test and index detections using TCM apparatus for auxiliary diagnosis and treatment and a photoplethysmograph.The detections were carried out repeatedly until there was no monotonic change in the value of the minimal SaO_(2d)uring a BH measurement(SaO_(2 min)) or in the duration of BH during a BH measurement(TBH).RESULTS:BH measurement and index detection data from 380 eligible cases were analyzed and a significant intergroup difference was found for 12 indexes.CONCLUSION:An index series for quantitative QDP measurement could comprise the 12 effective indexes:RSaO_(2d)(rate of decline of SaO_(2d)uring a BH measurement),RSaO_(2r)(recovery rate of SaO_2 after a BH measurement),SaO_(2 min),BFV(blood flow velocity),TSaO_(2d)(the time at which SaO_2 started declining during a BH measurement),TBH,TSa_(O2 min)(the time of occurrence of the minimal SaO_(2d)uring a BH measurement),TSa O_(2 max)(the time of occurrence of the maximal SaO_2 after a BH measurement),PTP(pulse-touching pressure),SBP(systolic blood pressure),PWV(pulse wave velocity),and DBP(diastolic blood pressure).Of the indexes,RSaO_(2d)could play akey role in quantitative QDP measurement;RSaO_(2r) and Sa O_2 mincould be used to differentiate the QDP symptom of shortness of breath and as early-warning indexes for chronic obstructive pulmonary disease.BFV,TSaO_(2d),and TBHcould be used to quantitatively assess the QDP symptoms of spontaneous perspiration and shortness of breath.
