张人亚:第一部党章“神秘守护人”的传奇人生

2012年7月16日，在中共二大召开暨中共党章诞生九十周年之际，国内首部完整体现中共二大历史的50分钟专题片《1922：指路明灯》由中共上海市委宣传部、中共上海市委党史研究室、上海广播电视台联合摄制，在上海电视台新闻综合频道和东方卫视首播。在拍摄这部专题片的过程中，中共二大通过的第一部党章的“神秘守护人”--早期共产党人张人亚的历史影像被首次发现和确认。而第一部党章被张人亚之父藏在空坟中长达20余年的传奇经历，也随之解密。

张人亚:清贫的金库主任

1921年,张静泉加入中国社会主义青年团,不久加入中国共产党,是中共早期党员。同年9月,上海金银业工人俱乐部成立,张静泉任主席,组织开展工人罢工斗争。次年,他去闸北商务印书馆工人合作社工作,并以张人亚的姓名从事工人运动,开始了他职业革命家的生涯。'四·一二'事变后,张人亚并没有离开上海,仍然在这里从事秘密的革命工作。

Protective effects of icariin on human umbilical vein endothelial cell injured by angiotensin Ⅱ

To investigate the effects of icariin （ICA） on angiotensin Ⅱ（Ang Ⅱ）-induced injury in human umbilical vein endothelial cells line （ECV-304）. The ECV-304 cells were cultured in vitro. After 24 h incubating with icariin, the model of AngⅡ-induced injury in ECV-304 was established. The cell viability （MTT method）, Lactate dehydrogenase （LDH） release and Nitric oxide （NO） production in the medium, the capacity of scavenging superoxide anion radicals （O2^-） and hydroxyl radicals （.OH） were measured. The activities of superoxide dismutase （SOD）, total nitric oxide synthase （T-NOS）, inducible nitric oxide synthase （iNOS） and constitutive nitric oxide synthase （cNOS） in the cells were determined. Compared with the Ang Ⅱ-treated group, ICA can significantly raise the viability of EC, increase the activities of SOD, T-NOS and cNOS, increase the production of NO, enhance the capacity of scavenging superoxide anion radicals （ O2^- ） and hydroxyl radicals（.OH）, and lower LDH leakage and iNOS activity. The results suggest that ICA can protect endothelial cells （ECV-304） from Ang II-induced injury.

张真人《金石灵砂论》外丹黄白考释

张真人《金石灵砂论》与外丹黄白之关系,学界迄今未有详论[1].作者考释认为,张真人生于唐神龙五年(707)而卒于唐贞元十六年(800),享年93岁.又今本《道藏》所题"蒙山张隐居撰",当为"雾山张隐居撰"之误;在丹药理论方面,该经实际包括了"阴阳相配原理"和"转化论"两个方面,它们贯穿于中国外丹黄白术的整个流变史中;在黄白的具体烧炼上,廓清了"铅"与"黑铅"的区别,使以往的诸多疑虑得以释然.事实说明,唐代道士在外丹黄白烧炼的温度控制和丹药性质的划分上,已形成一套有别于汉晋南北朝的方法和理论.

Human thrombin for the treatment of gastric and ectopic varices

AIM:To evaluate the efficacy of human thrombin in the treatment of bleeding gastric and ectopic varices.METHODS:Retrospective observational study in a Tertiary Referral Centre.Between January 1999-October 2005,we identified 37 patients who were endoscopically treated with human thrombin injection therapy for bleeding gastric and ectopic varices.Patient details including age,gender and aetiology of liver disease/segmental portal hypertension were documented.The thrombin was obtained from the Scottish National Blood Transfusion Service and prepared to give a solution of 250 IU/mL which was injected via a standard injection needle.All patient case notes were reviewed and the total dose of thrombin given along with the number of endoscopy sessions was recorded.Initial haemostasis rates,rebleeding rates and mortality were catalogued along with the incidence of any immediate complications which could be attributable to the thrombin therapy.The duration of follow up was also listed.The study was conducted according to the United Kingdom research ethics guidelines.RESULTS:Thirty-seven patients were included.33 patients(89%) had thrombin(250 U/mL) for gastric varices,2(5.4%) for duodenal varices,1 for rectal varices and 1 for gastric and rectal varices.(1) Gastric varices,an average of 15.2 mL of thrombin was used per patient.Re-bleeding occurred in 4 patients(10.8%),managed in 2 by a transjugular intrahepatic portosystemic shunt(TIPSS)(one unsuccessfully who died) and in other 2 by a distal splenorenal shunt;(2) Duodenal varices(or type 2 isolated gastric varices),an average of 12.5 mL was used per patient over 2-3 endoscopy sessions.Re-bleeding occurred in one patient,which was treated by TIPSS;and(3) Rectal varices,an average of 18.3 mL was used per patient over 3 endoscopy sessions.No re-bleeding occurred in this group.CONCLUSION:Human thrombin is a safe,easy to use and effective therapeutic option to control haemorrhage from gastric and ectopic varices.

Combination of a crude oil-degrading bacterial consortium under the guidance of strain tolerance and a pilot-scale degradation test

Under the guidance of strain tolerance, a new combination method for crude oil-degrading bacterial consortium was studied. Firstly, more than 50 efficient crude oil-degrading and biosurfactant producing bacteria were isolated from petroleum-contaminated soil and water in Tianjin Binhai New Area Oil field, China. Twenty-four of them were selected for further study. These strains were identified as belonging Pseudornonas aeruginosa, Bacillus subtilis, Brevibacillus brevis, Achrornobacter sp., Acinetobacter venetianus, Lysinibacillus rnacroides, Klebsiella oxytoca, Stenotrophornonas rhizophila, Rhodococcus sp. and Bacillus thuringiensis. A shake-flask degradation test revealed that 12 of these strains could degrade over 50% of 1% crude oil concentration in 7 d. Of these, 8 strains were able to produce biosurfactants. Furthermore, environmental tolerance experiments indicated that the majority of the strains had the ability to adapt to extreme environments including high temperatures, alkaline en- vironments and high salinity environments. A mixed bacterial agent comprising the strains WB2, W2, W3 and HA was developed based on the environmental tolerance tests and subjected to the pilot-scale degradation test indicating that this bacterial agent could degrade 85.2% of 0.8% crude oil concentration in 60 d. Our results suggest that the application of this mixed agent could remediate crude oil polluted soils in saline and alkaline environments.

Effects of Xin Mai Tong Capsule on Vasoregulatory Peptides in the Patients of Coronary Heart Disease

In order to inquire into the therapeutic effects of Xin Mai Tong Capsule (心脉通胶囊) on coronary heart disease with myocardial ischemia, 40 patients were randomly divided into two groups (Xin Mai Tong group and the control group). The plasma endothelin (ET) levels in the two groups of patients were markedly higher than that of the healthy people (P<0.001), and the calcitonin gene related peptide (CGRP) was similar to that of the healthy people (P>0.05). After treatment, ET and symptomatic scores in the two groups decreased markedly (P<0.01), and their S-T segments were elevated obviously (P<0.01). But the decrease of ET and symptomatic scores and elevation of S-T segment in Xin Mai Tong group were superior to those of the control group (P<0.05～0.01). The CGRP level in the control group did not vary obviously post-treatment, but it increased markedly (P<0.01) with the addition of Xin Mai Tong Capsule in Xin Mai Tong group.

Chronic constipation:Facilitator factor for development of varicocele

AIM:To evaluate the possible relationship between varicocele and chronic constipation.METHODS:Between April 2009 and May 2010,a total of 135 patients with varicocele or constipation and 120 healthy controls were evaluated.Patients were divided into two groups.In both groups detailed medical history was taken and all patients were examined physically by the same urologist and gastroenterologist.All of them were evaluated by color Doppler ultrasonography.All patients with constipation,except for the healthy controls of the second group,underwent a colonoscopy to identify the etiology of the constipation.In the first group,we determined the rate of chronic constipation in patients with varicocele and in the second group,the rate of varicocele in patients with chronic constipation.In both groups,the rate of the disease was compared with age-matched healthy controls.In the second group,the results of colonoscopies in the patients with chronic constipations were also evaluated.RESULTS:In the first group,mean age of the study and control groups were 22.9 ± 4.47 and 21.8 ± 7.21 years,respectively(P < 0.05).In the second group,mean age of the study and control groups were 52.8 ± 33.3 and 51.7 ± 54.3 years,respectively(P < 0.05).In the first group,chronic constipation was observed in 8 of the 69 patients with varicocele(11.6%) and 3 out of 60 in healthy controls(5%),respectively.In this regard,there was no statistical significance between varicocele patients and the healthy control(P = 0.37).In the second group,varicocele was observed in 16 of the 66 patients with chronic constipation(24.24%) and 12 out of 60 in healthy controls(20%) respectively.Similarly,there was no statistical significance between chronic constipation and healthy controls(P = 0.72).Internal/external hemorrhoids were detected in 4 of the 16 patients with chronic constipation and varicocele,in the second group.In the remaining 50 patients with chronic constipation 9 had internal/external hemorrhoids.In this regard,there was no statistical significance between chronic constipation and healthy controls(P = 0.80).CONCLUSION:Chronic constipation may not be a major predictive factor for the development of varicocele,but it may be a facilitator factor for varicocele.

Relationship between angiotensin-(1-7) and angiotensin Ⅱ correlates with hemodynamic changes in human liver cirrhosis

AIM： To measure circulating angiotensins at different stages of human cirrhosis and to further evaluate a possible relationship between renin angiotensin system （RAS） components and hemodynamic changes. METHODS： Patients were allocated into 4 groups： mild-to-moderate liver disease （MLD）, advanced liver disease （ALD）, patients undergoing liver transplantation, and healthy controls. Blood was collected to determine plasma renin activity （PRA）, angiotensin （Ang） Ⅰ, Ang Ⅱ, and Ang-（1-7） levels using radioimmunoassays. During liver transplantation, hemodynamic parameters were determined and blood was simultaneously obtained from the portal vein and radial artery in order to measure RAS components. RESULTS： PRA and angiotensins were elevated in ALD when compared to MLD and controls （P 〈 0.05）. In contrast, Ang Ⅱ was significantly reduced in MLD. Ang-（1-7）/Ang Ⅱ ratios were increased in MLD when compared to controls and ALD. During transplantation, Ang Ⅱ levels were lower and Ang-（1-7）/Ang Ⅱ ratios were higher in the splanchnic circulation than in the peripheral circulation （0.52 ± 0.08 vs 0.38 ±0.04, P 〈 0.02）, whereas the peripheral circulating Ang Ⅱ/Ang Ⅰ ratio was elevated in comparison to splanchnic levels （0.18 ±0.02 vs 0.13 ±0.02, P 〈 0.04）. Ang-（1-7）/ Ang Ⅱ ratios positively correlated with cardiac output （r = 0.66） and negatively correlated with systemic vascular resistance （r = -0.70）. CONCLUSION： Our findings suggest that the relationship between Ang-（1-7） and Ang Ⅱ may play a role in the hemodynamic changes of human cirrhosis.

Discussion on Sustainable Urbanization in Tibet

After 1995, Tibet entered the stage of accelerated urbanization. The large floating population fi＇om outside Tibet has become the driving force for urban expansion and the rising of urbanization rate. After analyzing the changes of urban functions and spatial structure of urban system in Tibet, this paper argues that before 1995 the urbanization in Tibet was mainly driven by administrative function, resulting in certain population migration, whereas in the past decade economic function has become the key factor accelerating urban expansion with the market mechanism creating large-scale inflow of population. The floating population-based urbanization and high population growth in the agricultural and pastoral areas of Tibet has promoted the regional economic prosperity, but exerted resources and environmental pressure and brought some problems for Tibetan culture protection at the same time. The conflicts and contradictions between urbanization and the sustainability of natural resources, environment and social development have been intensified. Addressing these problems, this paper proposes some countermeasures for improving the sustainability of Tibetan urbanization.

Brain natriuretic peptide is a potent vasodilator in aged human microcircula- tion and shows a blunted response in heart failure patients

Background Brain natriuretic peptide （BNP） is normally present in low levels in the circulation, but it is elevated in parallel with the degree of congestion in heart failure subjects （CHF）. BNP has natriuretic effects and is a potent vasodilator. It is suggested that BNP could be a therapeutic alternative in CHF. However, we postulated that the high levels of circulating BNP in CHF may downregulate the response of microvascular natriuretic receptors. This was tested by comparing 15 CHF patients （BNP 〉 3000 ng/L） with 10 matched, healthy controls. Methods Cutaneous microvascular blood flow in the forearm was measured by laser Doppler Flowmetry. Local heating （＋44°C, 10 min） was used to evoke a maximum local dilator response. Results Non-invasive iontophoretic administration of either BNP or acetylcholine （ACh）, a known endothelium-dependent dilator, elicited an increase in local flow. The nitric oxide synthase inhibitor, l-N-Arginine- methyl-ester （L-NAME）, blocked the BNP response （in controls）. Interestingly, responses to BNP in CHF patients were reduced to about one third of those seen in healthy controls （increase in flow： 251% in CHF vs. 908% in controls; P 〈 0.001）. In contrast, the vasodilator responses to ACh and to local heating were only somewhat attenuated in CHF patients. Thus, dilator capacity and nitric oxide signalling were not af- fected to the same extent as BNP-mediated dilation, indicating a specific downregulation of the latter response. Conclusions The findings show for the first time that microvascular responses to BNP are markedly reduced in CHF patients. This is consistent with the hypothesis of BNP receptor function is downregulated in CHF.

Sample based 3D face reconstruction from a single frontal image by adaptive locally linear embedding

In this paper, we propose a highly automatic approach for 3D photorealistic face reconstruction from a single frontal image. The key point of our work is the implementation of adaptive manifold learning approach. Beforehand, an active appearance model (AAM) is trained for automatic feature extraction and adaptive locally linear embedding (ALLE) algorithm is utilized to reduce the dimensionality of the 3D database. Then, given an input frontal face image, the corresponding weights between 3D samples and the image are synthesized adaptively according to the AAM selected facial features. Finally, geometry reconstruction is achieved by linear weighted combination of adaptively selected samples. Radial basis function (RBF) is adopted to map facial texture from the frontal image to the reconstructed face geometry. The texture of invisible regions between the face and the ears is interpolated by sampling from the frontal image. This approach has several advantages: (1) Only a single frontal face image is needed for highly automatic face reconstruction; (2) Compared with former works, our reconstruction approach provides higher accuracy; (3) Constraint based RBF texture mapping provides natural appearance for reconstructed face.

Models of Presence and Loss of Transcendence in History

The article seeks to elucidate the status of transcendence in the historiography of secularization through the perspective of collective memory. It discusses two typological models dealing with the basic metaphysical problem concerned with the presence and meaning of transcendence in real human existence. According to the first, the historical reality of secularization causes a break from the collective memory whose roots are in religion. In contrast, the second model considers that despite the deep transformations in the status of religion in a reality of secularization, an experience of historical continuity may also occur there. These models denote the two poles in the argument about the meaning and value of history for modem people. The article suggests a phenomenological analysis of the two models and criticizes their deficiencies. Finally, the ＂tension model＂ is outlined as a third alternative that aims at overcoming the binary situation created by the first two in favor of a perspective that necessitates and contains both immanence and transcendence.

Spontaneous diffuse vasospasm simultaneously found at left main trunk, left anterior descending, left circumflex and right coronary arteries

Coronary artery spasm （CAS） is found not only in Asian but also in white patients. CAS can lead to angina pecto- ris, myocardial infarction, ventricular arrhythmias and sud- den cardiac death. But CAS diagnosis is not necessarily easy, and it also remains highly challenging to therapy and prevention. We present a spontaneous extensive-CAS case with typical clinical features of acute myocardial infarction, despite the regular vasodilator treatment.

380 CASES OF BRONCHIECTASIS WITH HEMOPTYSIS TREATED BY POINT-INJECTION

Hemoptysis,especially the massivehemoptysis caused by bronchiectasis is acommon,but emergent and critical diseases inclinic.Injection of Herba Houttuyniae extractinto Kongzui(LU 6)was performed to treathemoptysis according to the theory oftraditional Chinese medicine and the

Effects of angiotensinogen gene polymorphisms on the risk of coronary heart disease in the Chinese population： a meta-analysis

Objective Coronary heart disease （CHD） is a multifactorial disease. This meta-analysis was performed to evaluate the relationship between angiotensinogen gene polymorphisms and CHD in the Chinese population. Methods We searched literature in pubmed （1990- 2010.8） and CNKI （1990-2010.8） for all the relevant studies on 2 angiotensinogen polymorphisms （M235T and T174M） and risk of CHD. The meta-analysis software Stata 10.0 was used for ascertaining heterogeneity among individual studies and for combining all the studies. Furthermore,Egger＇s test and sensitivity analysis were performed to insure authenticity of the outcome.Results Ten associations studies on 2 angiotensinogen polymorphisms （M235T and T174M） were included in this meta-analysis. In a combined analysis, the summary per-allele odds ratio for CHD of the M235T polymorphism was 1.374 （95% confidence interval, 1.019 to 1.852） and T174M polymorphism was 4.089 （95% confidence interval, 1.697 to 9.851）. Conclusions The M235T polymorphism had weak but statistically significant association with CHD while the T174M polymorphism was more strongly associated with a CHD risk in Chinese population, but further confirmation studies are needed

Personal Adaptation and Spiritual Potential in Childhood Today in the Lithuania

The Lithuania 2011 Childhood is not just a product of human development but also a product of society＇s educational and spiritual culture development. This paper aims to disclose how nowadays the family helps the child to develop adaptation instruments which would help to adapt to the society in a micromacro environment, to show what helps the child to become a member of a social group, of the society, what adaptation problems arise during the childhood. Problems of school adaptation of the first-formers have not been properly assessed and analysed so far, though they foresee the future. No proper attention has been paid to the development of the harmonious personality during the pre-school period and to the correction of their adaptation during the firstschool year. The paper deals with the child＇s experiences of the pre-school period as the factor influencing school adaptation in the first form. Variety and quality of children＇s experiences are directly related and most of all depend on the family of the spiritual institution, so its impact is the strongest in terms of the development of the child＇s personality. The goal is to disclose the importance of selfdevelopment in childhood, which determines future success. The object is selfdevelopment during childhood today in the Lithuania. Methods of investigation are： the analysis of pedagogical, psychological, philosophical literature; the analysis of empiri.cal researches and statistic data; and the method of observation. The hypothesis is： The cause of the firstformers＇ school adaptation difficulties incompletely realised adaptation potential during the preschool period.

行业特色高校外语“3+”培养模式创新与实践——以西安某高校高起点班为例

文章在高校人才培养多元化的趋势和大学英语改革的新背景下,以西安某行业特色型高校为例,论述了高起点本科生英语培养方案、目标及课程设置。并通过社会调查和课堂教学实践构建了一个针对高水平本科生的外语培养及教学模式,试图解决目前理工科院校大学英语课程设置不合理及教学模式单一的现象,为当前的高校的外语教育和外语改革提供一定的借鉴和参考作用。

Tension Active Disturbance Rejection Control of Automatic Yarn Splicing Robots for Ring Spinning

Automatic splicing of interrupted yarns in ring spinning has always been a problem in the industry.Factors such as low yarn strengths and environmental influence on yarn tensions make it difficult to control the yarn tension during the robotic splicing process.The purpose of this research is to design active disturbance rejection control(ADRC)for a third-order nonlinear tension system subject to external disturbances.Firstly,a third-order extended state observer(ESO)is designed to achieve the suppression and the compensation of the internal modeling error and the external disturbances of the system.Secondly,the adaptive gain error feedback control and the filtering process are designed to reduce the influence of sensor noise on the disturbance observation.Finally,the tension control during the splicing process is simulated and experimented,and the experiments show that the method has good robustness in the tension tracking task under a dynamic environment,which verifies the effectiveness of the method.

张元济致斯坦因英文信函

由张人凤收集、整理,商务印书馆出版的《张元济全集》,是张元济一生留下的最全面的文字史料。从2007年9月开始出版,至2010年11月出齐,共十卷本。按体裁分类编辑,包括书信、诗、文、日记以及古籍研究五类。