Upper gastrointestinal tract hemorrhage （UGIH） remains a common presentation requiring urgent evaluation and treatment. Accurate assessment, appropriate intervention and apt clinical skills are needed for proper man...Upper gastrointestinal tract hemorrhage （UGIH） remains a common presentation requiring urgent evaluation and treatment. Accurate assessment, appropriate intervention and apt clinical skills are needed for proper management from time of presentation to discharge. The advent of pharmacologic acid suppression, endoscopic hemostatic techniques, and recognition of Helicobacter pylori as an etiologic agent in peptic ulcer disease （PUD） has revolutionized the treatment of UGIH. Despite this, acute UGIH still carries considerable rates of morbidity and mortality. This review aims to discuss current areas of uncertainty and controversy in the management of UGIH. Neoadjuvant proton pump inhibitor （PPI） therapy has become standard empiric treatment for UGIH given that PUD is the leading cause of non variceal UGIH, and PPIs are extremely effective at promoting ulcer healing. Howeve, neoadjuvant PPI administration has not been shown to affect hard clinical outcomes such as rebleeding or mortality. The optimal timing of upper endoscopy in UGIH is often debated. Upon completion of volume resuscitation and hemodynamic stabilization, upper endoscopy should be performed within 24 h in all patientswith evidence of UGIH for both diagnostic and therapeutic purposes. With rising healthcare cost paramount in today＇s medical landscape, the ability to appropriately triage UGIH patients is of increasing value. Upper en- doscopy in conjunction with the clinical scenario allows for accurate decision making concerning early discharge home in low risk lesions or admission for further moni toring and treatment in higher risk lesions. Concomitant pharmacotherapy with non steroidal antiinflammatory drugs （NSAIDs） and antiplatelet agents, such as clopidogrel, has a major impact on the etiology, severib/, and potential treatment of UGIH. Long term PPI use in patients taking chronic NSAIDs or clopidogrel is discussed thoroughly in this review.展开更多
In this paper, by using the symmetry method, the relationships between new explicit solutions and old ones of the （2＋1）-dimensional Kaup-Kupershmidt （KK） equation are presented. We successfully obtain more genera...In this paper, by using the symmetry method, the relationships between new explicit solutions and old ones of the （2＋1）-dimensional Kaup-Kupershmidt （KK） equation are presented. We successfully obtain more general exact travelling wave solutions for （2＋ 1）-dimensional KK equation by the symmetry method and the （G1/G）-expansion method. Consequently, we find some new solutions of （2＋1）-dimensional KK equation, including similarity solutions, solitary wave solutions, and periodic solutions.展开更多
Based on the theory of semi-global classical solutions to quasilinear hyperbolic systems, the local exact boundary observability for a kind of second-order quasilinear hyperbolic systems is obtained by a constructive ...Based on the theory of semi-global classical solutions to quasilinear hyperbolic systems, the local exact boundary observability for a kind of second-order quasilinear hyperbolic systems is obtained by a constructive method.展开更多
The main purpose of this paper is to investigate the exact solutions of plane symmetric spacetime in the context of f(R,T)gravity[Phys.Rev.D 84(2011)024020],where f(R,T)is an arbitrary function of Ricci scalar R and t...The main purpose of this paper is to investigate the exact solutions of plane symmetric spacetime in the context of f(R,T)gravity[Phys.Rev.D 84(2011)024020],where f(R,T)is an arbitrary function of Ricci scalar R and trace of the energy momentum tensor T.We explore the exact solutions for two different classes of f(R,T)models.The first class f(R,T)=R+2f(T)yields a solution which corresponds to Taub's metric while the second class f(R,T)=f_1(R)+f_2(T)provides two additional solutions which include the well known anti-deSitter spacetime.The energy densities and corresponding functions for f(R,T)models are evaluated in each case.展开更多
文摘Upper gastrointestinal tract hemorrhage （UGIH） remains a common presentation requiring urgent evaluation and treatment. Accurate assessment, appropriate intervention and apt clinical skills are needed for proper management from time of presentation to discharge. The advent of pharmacologic acid suppression, endoscopic hemostatic techniques, and recognition of Helicobacter pylori as an etiologic agent in peptic ulcer disease （PUD） has revolutionized the treatment of UGIH. Despite this, acute UGIH still carries considerable rates of morbidity and mortality. This review aims to discuss current areas of uncertainty and controversy in the management of UGIH. Neoadjuvant proton pump inhibitor （PPI） therapy has become standard empiric treatment for UGIH given that PUD is the leading cause of non variceal UGIH, and PPIs are extremely effective at promoting ulcer healing. Howeve, neoadjuvant PPI administration has not been shown to affect hard clinical outcomes such as rebleeding or mortality. The optimal timing of upper endoscopy in UGIH is often debated. Upon completion of volume resuscitation and hemodynamic stabilization, upper endoscopy should be performed within 24 h in all patientswith evidence of UGIH for both diagnostic and therapeutic purposes. With rising healthcare cost paramount in today＇s medical landscape, the ability to appropriately triage UGIH patients is of increasing value. Upper en- doscopy in conjunction with the clinical scenario allows for accurate decision making concerning early discharge home in low risk lesions or admission for further moni toring and treatment in higher risk lesions. Concomitant pharmacotherapy with non steroidal antiinflammatory drugs （NSAIDs） and antiplatelet agents, such as clopidogrel, has a major impact on the etiology, severib/, and potential treatment of UGIH. Long term PPI use in patients taking chronic NSAIDs or clopidogrel is discussed thoroughly in this review.
基金Supported by the Natural Science Foundation of Shandong Province in China under Grant No.Q2005A01
文摘In this paper, by using the symmetry method, the relationships between new explicit solutions and old ones of the （2＋1）-dimensional Kaup-Kupershmidt （KK） equation are presented. We successfully obtain more general exact travelling wave solutions for （2＋ 1）-dimensional KK equation by the symmetry method and the （G1/G）-expansion method. Consequently, we find some new solutions of （2＋1）-dimensional KK equation, including similarity solutions, solitary wave solutions, and periodic solutions.
基金supported by the National Natural Science Foundation of China(No.11526050)
文摘Based on the theory of semi-global classical solutions to quasilinear hyperbolic systems, the local exact boundary observability for a kind of second-order quasilinear hyperbolic systems is obtained by a constructive method.
基金National University of Computer and Emerging Sciences(NUCES) for funding support through research reward programme
文摘The main purpose of this paper is to investigate the exact solutions of plane symmetric spacetime in the context of f(R,T)gravity[Phys.Rev.D 84(2011)024020],where f(R,T)is an arbitrary function of Ricci scalar R and trace of the energy momentum tensor T.We explore the exact solutions for two different classes of f(R,T)models.The first class f(R,T)=R+2f(T)yields a solution which corresponds to Taub's metric while the second class f(R,T)=f_1(R)+f_2(T)provides two additional solutions which include the well known anti-deSitter spacetime.The energy densities and corresponding functions for f(R,T)models are evaluated in each case.
