A 3D stereotomography algorithm, which is derived from the 3D Cartesian coordinate, is applied for the first time to the deep-sea data acquired in the LH area, South China Sea, to invert a macro velocity model for pre...A 3D stereotomography algorithm, which is derived from the 3D Cartesian coordinate, is applied for the first time to the deep-sea data acquired in the LH area, South China Sea, to invert a macro velocity model for pre-stack depth migration. The successful implementation of stereotomography is highly dependent on the correct extraction of slowness components and the proper application of regularization terms. With the help of the structure tensor algorithm, a high-quality 3D stereotomography data space is achieved in a very efficient manner. Then, considering that the horizontal slowness in cross-line direction is usually unavailable for 3D narrow-azimuth data, the regularization terms must be enhanced to guarantee a stable convergence of the presented algorithm. The inverted model serves as a good model for the 3D pre-stack depth migration. The synthetic and real data examples demonstrated the robustness and effectiveness of the presented algorithm and the related schemes.展开更多
Parametric instability of a riser is caused by fluctuation of its tension in time due to the heave motion of floating platform. Many studies have tackled the problem of parametric instability of a riser with constant ...Parametric instability of a riser is caused by fluctuation of its tension in time due to the heave motion of floating platform. Many studies have tackled the problem of parametric instability of a riser with constant tension. However, tension in the riser actually varies linearly from the top to the bottom due to the effect of gravity. This paper presents the parametric instability analysis of deepwater top-tensioned risers(TTR) considering the linearly varying tension along the length. Firstly, the governing equation of transverse motion of TTR under parametric excitation is established. This equation is reduced to a system of ordinary differential equations by using the Galerkin method. Then the parametric instability of TTR for three calculation models are investigated by applying the Floquet theory. The results show that the natural frequencies of TTR with variable tension are evidently reduced, the parametric instability zones are significantly increased and the maximum allowable amplitude of platform heave is much smaller under the same damping; The nodes and antinodes of mode shape are no longer uniformly distributed along the axial direction and the amplitude also changes with depth, which leads to coupling between the modes. The combination resonance phenomenon occurs as a result of mode coupling, which causes more serious damage.展开更多
Zhang Xichun classifed the collapse syndrome into upper collapse,lower collapse and exterior col-lapse.Based on the therapeutic principle of tonifying the liver and astringing the liver to consolidate collapse,he used...Zhang Xichun classifed the collapse syndrome into upper collapse,lower collapse and exterior col-lapse.Based on the therapeutic principle of tonifying the liver and astringing the liver to consolidate collapse,he used drugs boldly to cure disease.The method of tonifying the liver and astringing sweating is applied to res-cue exterior collapse with Laifu Deoction(来复汤);the method of tonifying the liver and relieving asthma is applied to treat upper collapse with Shenzhe Zhenqi Decoction(参赭镇气汤);the method of restoring yang with emergent treatment is applied to rescue the lower collapse with Jijiu Huiyang Decoction(急救回阳汤).This will provide references for the prevention and treatment of critical diseases for later generations in practi-cing Chinese medicine.展开更多
Some drugs exert curative effects intracellu- larly, but their hydrophilic property prohibits the mem- brane-penetrating process and thus limits the curative efficacies, although this property guarantee their solubili...Some drugs exert curative effects intracellu- larly, but their hydrophilic property prohibits the mem- brane-penetrating process and thus limits the curative efficacies, although this property guarantee their solubility in aqueous phase. An example is sodium tanshinone II-A sulfonate (DS-201), a derivative of Chinese medical herb Danshen (Salvia miltiorrhiza) which is a BKc~ channel opener and a vasodilator. This study established and opti- mized a liposome delivery system which could pack and deliver DS-201 into HEK293 cells transfected with BKca channels, and DS-201 given this way significantly increased the open probability of BKca channel from baseline 0.013 ~ 0.004 to 0.036 -4- 0.011 at -t-40 mV membrane potential (P 〈 0.05) in single-channel attached study, and also increased the current density from baseline 23.2 + 4.4 to 66.0 4- 15.2 pA/pF at +40 mV membrane potential (P 〈 0.05), compared with the direct extracellular administration of this drug. Moreover, showing a ~ 60 % inhibition of the PE or PGF2a induced vascular constric- tion, the DS-201 liposomes did posses significantly enhanced vasorelaxant effect on rat mesenteric artery, compared with 20 % inhibition of the directly administration of this drug (P 〈 0.05), suggesting that DS-201 delivered by liposomes significantly improved the drug's vasorelaxing effect. Taken together, the optimized DS-201 liposomes in our study successfully delivered DS-201 into cells and thus significantly activated BKca channels to reverse the contraction induced by PE and PGF2a, attesting the enhanced bioavailability.展开更多
A-manifolds and/3-manifolds, introduced by Gray (1978), are two significant classes of Einstein-like Riemannian manifolds. A Riemannian manifold is Ricci parallel if and only if it is simultaneously an A-manifold an...A-manifolds and/3-manifolds, introduced by Gray (1978), are two significant classes of Einstein-like Riemannian manifolds. A Riemannian manifold is Ricci parallel if and only if it is simultaneously an A-manifold and a B-manifold. The present paper proves that both focal submanifolds of each isoparametric hypersurface in unit spheres with g = 4 distinct principal curvatures are A-manifolds. As for the focal submanifolds with g = 6, m = 1 or 2, only one is an A-manifold, and neither is a B-manifold.展开更多
We consider the tensor product π_α ? π_βof complementary series representations π_α and π_β of classical rank one groups SO_0(n, 1), SU(n, 1) and Sp(n, 1). We prove that there is a discrete component π_(α+β...We consider the tensor product π_α ? π_βof complementary series representations π_α and π_β of classical rank one groups SO_0(n, 1), SU(n, 1) and Sp(n, 1). We prove that there is a discrete component π_(α+β)for small parameters α and β(in our parametrization). We prove further that for SO_0(n, 1) there are finitely many complementary series of the form π_(α+β+2j,)j = 0, 1,..., k, appearing in the tensor product π_α ? π_βof two complementary series π_α and π_β, where k = k(α, β, n) depends on α, β and n.展开更多
基金funded by China Natural Science Foundation(Nos.41574098 and 41630964)China key specialized project(No.2016ZX05026-001-03)
文摘A 3D stereotomography algorithm, which is derived from the 3D Cartesian coordinate, is applied for the first time to the deep-sea data acquired in the LH area, South China Sea, to invert a macro velocity model for pre-stack depth migration. The successful implementation of stereotomography is highly dependent on the correct extraction of slowness components and the proper application of regularization terms. With the help of the structure tensor algorithm, a high-quality 3D stereotomography data space is achieved in a very efficient manner. Then, considering that the horizontal slowness in cross-line direction is usually unavailable for 3D narrow-azimuth data, the regularization terms must be enhanced to guarantee a stable convergence of the presented algorithm. The inverted model serves as a good model for the 3D pre-stack depth migration. The synthetic and real data examples demonstrated the robustness and effectiveness of the presented algorithm and the related schemes.
基金supported by the National Natural Science Foundation of China (51239008, 51279130, 51079097)Science Fund for Creative Research Groups of the National Natural Science Foundation of China (51021004)
文摘Parametric instability of a riser is caused by fluctuation of its tension in time due to the heave motion of floating platform. Many studies have tackled the problem of parametric instability of a riser with constant tension. However, tension in the riser actually varies linearly from the top to the bottom due to the effect of gravity. This paper presents the parametric instability analysis of deepwater top-tensioned risers(TTR) considering the linearly varying tension along the length. Firstly, the governing equation of transverse motion of TTR under parametric excitation is established. This equation is reduced to a system of ordinary differential equations by using the Galerkin method. Then the parametric instability of TTR for three calculation models are investigated by applying the Floquet theory. The results show that the natural frequencies of TTR with variable tension are evidently reduced, the parametric instability zones are significantly increased and the maximum allowable amplitude of platform heave is much smaller under the same damping; The nodes and antinodes of mode shape are no longer uniformly distributed along the axial direction and the amplitude also changes with depth, which leads to coupling between the modes. The combination resonance phenomenon occurs as a result of mode coupling, which causes more serious damage.
基金We thank for the funding support from the Scientific Research Project of Hunan Provincial Department of Education(18C0378)。
文摘Zhang Xichun classifed the collapse syndrome into upper collapse,lower collapse and exterior col-lapse.Based on the therapeutic principle of tonifying the liver and astringing the liver to consolidate collapse,he used drugs boldly to cure disease.The method of tonifying the liver and astringing sweating is applied to res-cue exterior collapse with Laifu Deoction(来复汤);the method of tonifying the liver and relieving asthma is applied to treat upper collapse with Shenzhe Zhenqi Decoction(参赭镇气汤);the method of restoring yang with emergent treatment is applied to rescue the lower collapse with Jijiu Huiyang Decoction(急救回阳汤).This will provide references for the prevention and treatment of critical diseases for later generations in practi-cing Chinese medicine.
基金supported by the National Natural Science Foundation of China(3067076381173661+2 种基金31300948)the Sichuan Technology and Education Committee(2011FZ0106and XYTD20100509ZZ010)
文摘Some drugs exert curative effects intracellu- larly, but their hydrophilic property prohibits the mem- brane-penetrating process and thus limits the curative efficacies, although this property guarantee their solubility in aqueous phase. An example is sodium tanshinone II-A sulfonate (DS-201), a derivative of Chinese medical herb Danshen (Salvia miltiorrhiza) which is a BKc~ channel opener and a vasodilator. This study established and opti- mized a liposome delivery system which could pack and deliver DS-201 into HEK293 cells transfected with BKca channels, and DS-201 given this way significantly increased the open probability of BKca channel from baseline 0.013 ~ 0.004 to 0.036 -4- 0.011 at -t-40 mV membrane potential (P 〈 0.05) in single-channel attached study, and also increased the current density from baseline 23.2 + 4.4 to 66.0 4- 15.2 pA/pF at +40 mV membrane potential (P 〈 0.05), compared with the direct extracellular administration of this drug. Moreover, showing a ~ 60 % inhibition of the PE or PGF2a induced vascular constric- tion, the DS-201 liposomes did posses significantly enhanced vasorelaxant effect on rat mesenteric artery, compared with 20 % inhibition of the directly administration of this drug (P 〈 0.05), suggesting that DS-201 delivered by liposomes significantly improved the drug's vasorelaxing effect. Taken together, the optimized DS-201 liposomes in our study successfully delivered DS-201 into cells and thus significantly activated BKca channels to reverse the contraction induced by PE and PGF2a, attesting the enhanced bioavailability.
基金supported by National Natural Science Foundation of China(Grant No.11301027)the Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20130003120008)+1 种基金the Beijing Natural Science Foundation(Grant No.1144013)the Fundamental Research Funds for the Central Universities(Grant No.2012CXQT09)
文摘A-manifolds and/3-manifolds, introduced by Gray (1978), are two significant classes of Einstein-like Riemannian manifolds. A Riemannian manifold is Ricci parallel if and only if it is simultaneously an A-manifold and a B-manifold. The present paper proves that both focal submanifolds of each isoparametric hypersurface in unit spheres with g = 4 distinct principal curvatures are A-manifolds. As for the focal submanifolds with g = 6, m = 1 or 2, only one is an A-manifold, and neither is a B-manifold.
文摘We consider the tensor product π_α ? π_βof complementary series representations π_α and π_β of classical rank one groups SO_0(n, 1), SU(n, 1) and Sp(n, 1). We prove that there is a discrete component π_(α+β)for small parameters α and β(in our parametrization). We prove further that for SO_0(n, 1) there are finitely many complementary series of the form π_(α+β+2j,)j = 0, 1,..., k, appearing in the tensor product π_α ? π_βof two complementary series π_α and π_β, where k = k(α, β, n) depends on α, β and n.