目的:评价瞬时弹性波监测仪在慢性乙型肝炎疾病进展中的应用价值。方法:选取127例慢性乙型肝炎肝纤维化患者,根据肝脏的病理分期,按照纤维化程度不同将其分为肝纤维化S1期组(30例)、S2期组(35例)、S3期组(32例)及S4期组(30例),分别采用F...目的:评价瞬时弹性波监测仪在慢性乙型肝炎疾病进展中的应用价值。方法:选取127例慢性乙型肝炎肝纤维化患者,根据肝脏的病理分期,按照纤维化程度不同将其分为肝纤维化S1期组(30例)、S2期组(35例)、S3期组(32例)及S4期组(30例),分别采用Fibroscan诊断仪测量4组患者的肝脏硬度(FS)值,同时绘制4组患者FS值的受试者工作特征曲线,计算曲线下面积和诊断的特异度及灵敏性。结果:Fibroscan诊断仪测量4组患者的FS值差异有统计学意义(F=1597.89,P<0.05),且以S4期组患者的FS值最高。S1期组,S2期组、S3期组和S4期组的曲线下面积分别为0.766、0.862、0.891和0.805,诊断的界值分别为10.0 k Pa、10.7 k Pa、11.9 k Pa和15.2 k Pa,灵敏度分别为75.4%、76.8%、85.3%及75.2%,特异度分别为80.5%、69.9%、66.2%及76.8%。结论:瞬时弹性波监测在慢性乙型肝炎疾病肝硬化分期和评估慢性乙型肝炎疾病进展中的诊断特异性和灵敏度均较高,且检查手段无创。展开更多
Knowledge of the locations of seismic sources is critical for microseismic monitoring. Time-window-based elastic wave interferometric imaging and weighted- elastic-wave （WEW） interferometric imaging are proposed and...Knowledge of the locations of seismic sources is critical for microseismic monitoring. Time-window-based elastic wave interferometric imaging and weighted- elastic-wave （WEW） interferometric imaging are proposed and used to locate modeled microseismic sources. The proposed method improves the precision and eliminates artifacts in location profiles. Numerical experiments based on a horizontally layered isotropic medium have shown that the method offers the following advantages： It can deal with Iow-SNR microseismic data with velocity perturbations as well as relatively sparse receivers and still maintain relatively high precision despite the errors in the velocity model. Furthermore, it is more efficient than conventional traveltime inversion methods because interferometric imaging does not require traveltime picking. Numerical results using a 2D fault model have also suggested that the weighted-elastic-wave interferometric imaging can locate multiple sources with higher location precision than the time-reverse imaging method.展开更多
文摘目的:评价瞬时弹性波监测仪在慢性乙型肝炎疾病进展中的应用价值。方法:选取127例慢性乙型肝炎肝纤维化患者,根据肝脏的病理分期,按照纤维化程度不同将其分为肝纤维化S1期组(30例)、S2期组(35例)、S3期组(32例)及S4期组(30例),分别采用Fibroscan诊断仪测量4组患者的肝脏硬度(FS)值,同时绘制4组患者FS值的受试者工作特征曲线,计算曲线下面积和诊断的特异度及灵敏性。结果:Fibroscan诊断仪测量4组患者的FS值差异有统计学意义(F=1597.89,P<0.05),且以S4期组患者的FS值最高。S1期组,S2期组、S3期组和S4期组的曲线下面积分别为0.766、0.862、0.891和0.805,诊断的界值分别为10.0 k Pa、10.7 k Pa、11.9 k Pa和15.2 k Pa,灵敏度分别为75.4%、76.8%、85.3%及75.2%,特异度分别为80.5%、69.9%、66.2%及76.8%。结论:瞬时弹性波监测在慢性乙型肝炎疾病肝硬化分期和评估慢性乙型肝炎疾病进展中的诊断特异性和灵敏度均较高,且检查手段无创。
基金supported by the R&D of Key Instruments and Technologies for Deep Resources Prospecting(No.ZDYZ2012-1)National Natural Science Foundation of China(No.11374322)
文摘Knowledge of the locations of seismic sources is critical for microseismic monitoring. Time-window-based elastic wave interferometric imaging and weighted- elastic-wave （WEW） interferometric imaging are proposed and used to locate modeled microseismic sources. The proposed method improves the precision and eliminates artifacts in location profiles. Numerical experiments based on a horizontally layered isotropic medium have shown that the method offers the following advantages： It can deal with Iow-SNR microseismic data with velocity perturbations as well as relatively sparse receivers and still maintain relatively high precision despite the errors in the velocity model. Furthermore, it is more efficient than conventional traveltime inversion methods because interferometric imaging does not require traveltime picking. Numerical results using a 2D fault model have also suggested that the weighted-elastic-wave interferometric imaging can locate multiple sources with higher location precision than the time-reverse imaging method.
