均匀设计法优选“彝族验方痛经贴”基质配方

目的:筛选彝族验方痛经贴基质。方法:采用均匀设计法,以粘着强度为评价指标,以所得回归方程对基质组成比例进行优化。结果:确定基质的最佳配比为:明胶∶聚丙烯酸钠∶PVA∶PEG400∶甘油∶CMC-Na∶PVP∶高岭土=1∶4∶8∶10∶6∶6∶12∶0.5结论:采用该配方可与中药提取物配合,载药量大,透气性好,无渗药现象,还可反复粘贴,稳定性好,无致敏性与刺激性。

彝族验方痛经贴巴布剂成型工艺的研究

目的:优选痛经贴巴布剂制备工艺的最佳条件。方法:用正交法设计实验,以粘着力、雪上一枝蒿总碱的透皮速率常数和累积透过率为考察指标,综合评价痛经贴成型工艺的几种影响因素:氮酮、丙二醇、空白基质与浸膏量之配比。结果:制备工艺的最佳条件为:空白基质与浸膏量之比为4∶1,加入1%氮酮和8%丙二醇。结论:应用本法制备的痛经贴其粘着力、透皮速率常数和累积透过率都比较好,且制备简单、质量可控。

彝族验方葛根茯苓汤防醉酒作用的实验研究

目的:了解彝族验方葛根茯苓汤的防醉酒作用。方法:通过小鼠乙醇急性中毒实验,小鼠平衡失调实验,小鼠醉酒睡眠实验,大鼠胃溃疡实验,观察不同剂量葛根茯苓汤水煎液一次性灌服的防醉酒作用和抗乙醇性胃溃疡作用。结果:葛根茯苓汤各剂量均可明显降低乙醇急性中毒小鼠死亡率,增加转棒未坠落小鼠数,延长醉酒睡眠潜伏期,缩短醉酒睡眠时间;高剂量组可降低乙醇性大鼠的胃溃疡指数。结论:彝族验方葛根茯苓汤对小鼠酒精急性中毒有预防作用,并能对抗乙醇引起的小鼠平衡失调及大鼠胃黏膜损伤。

Analysis on the characteristics of Yi nationality herbal single experience prescription in wuliangshan district

Yi nationality medicine is an important part of traditional Chinese medicine. It has both the connotation of traditional Chinese medicine and distinct national and medicinal characteristics. Many of the single experience prescriptions circulated among the Yi people in Wuliangshan areas originate from the classics. They attach importance to diet therapy, medication according to local sources, flexible treatment, remarkable curative effect, and unique medication bath method for women during childbirth and Han (Xian) jiao therapy in Beginning of Summer, which deserve our attention.