目的调节是人眼调节视力的过程,现有的调节理论对调节过程中悬韧带张力分配的解释存在分歧,由于成像技术的限制,尚无法验证其准确性。在接受囊外摘除术的眼睛中,不同的悬韧带张力分配对囊膜形态有较大影响且容易被在体观测。本研究结合...目的调节是人眼调节视力的过程,现有的调节理论对调节过程中悬韧带张力分配的解释存在分歧,由于成像技术的限制,尚无法验证其准确性。在接受囊外摘除术的眼睛中,不同的悬韧带张力分配对囊膜形态有较大影响且容易被在体观测。本研究结合有限元分析方法与眼部超声显微成像,探究悬韧带张力分配对无晶体基质囊膜形态的影响。方法建立接受囊外摘除术后的一系列囊膜有限元模型,设定前囊环切口直径在1.5~6.5 mm之间。模型受前部(AZ)、赤道部(EZ)和后部悬韧带(PZ)的共同作用。设定总悬韧带张力为0.75 m N时为非调节态,模拟两种调节过程中的悬韧带张力分配:(1)EZ上的力逐渐增大至30 m N,AZ和PZ上的合力减小至0 m N;(2)所有悬韧带上的力都减小至0 m N。分析不同悬韧带张力分配下囊膜的形态变化。结果当EZ上的力随着其他悬韧带合力的减小而增加时,后囊表现出向后弯曲,这与恒河猴的超声在体成像结果一致。后囊向后弯曲的程度与前囊切口大小及EZ张力大小呈正相关。当所有悬韧带张力都减小时,囊膜形变方向与在体观测结果相反。结论赤道悬韧带对调节态下的囊膜形态有主要影响,调节态下仅赤道悬韧带紧张的模式与真实情况更加接近,这与Schachar理论的描述一致。展开更多
The close relationship between the structure,evolution,and resources environment of the South China Sea is a current research focus and also a focal point of our study.In this paper,we use regional seismic sections to...The close relationship between the structure,evolution,and resources environment of the South China Sea is a current research focus and also a focal point of our study.In this paper,we use regional seismic sections to analyze the relationship between seismic facies and the structure and tectonic evolution of the northeastern South China Sea and propose new points about the structure and the direction of block(land mass) motion.First,the tectonic features are clear and can be divided into five different structural units which are both linked and independent of each other.Second,it doesn't matter if the South China Sea basin pattern is extensional,weakly compressive,or strongly compressive,the regional tectonic stress field is unified.For the first time we find that two shallow subduction zones are recognized in the seismic profiles.All the tectonic blocks have accordion-fold-style structures,converging in the east,and the South China Sea exhibits different stages of basin development:growth, maturity,end,and termination.The block subduction and regional block dip directions are all aligned with the regional stress field.展开更多
This paper presents some investigations on the effect of processing parameters on the emission of electromagnetic radiation (EMR) during plastic deformation and crack propagation in copper-zinc alloys. Timing of the...This paper presents some investigations on the effect of processing parameters on the emission of electromagnetic radiation (EMR) during plastic deformation and crack propagation in copper-zinc alloys. Timing of the EMR emissions, maximum stress during crack instability, stress-intensity factor, elastic strain energy release rate, maximum EMR amplitude, RMS value of EMR amplitude, EMR frequency and electromagnetic energy release rate were analysed for the effect of rolling directions at different percentage of zinc content in Cu-Zn alloy specimens. The same parameters were also analysed for 68-32 Cu-Zn alloy specimens at different annealing temperatures and at different angles 0, to the rolling direction. EMR emissions are observed to be highly anisotropic in nature. At θ=45° to 60°, marked changes in mechanical and electromagnetic parameters were observed. Specimens annealed at 500℃, just above the recrystallization temperature, and at 700℃, when grain-size growth is rapid, EMR responses have been found to have well-defined patterns.展开更多
The pile-soil system interaction computational model in liquefaction-induced lateral spreading ground was established by the finite difference numerical method.Considering an elastic-plastic subgrade reaction method,n...The pile-soil system interaction computational model in liquefaction-induced lateral spreading ground was established by the finite difference numerical method.Considering an elastic-plastic subgrade reaction method,numerical methods involving finite difference approach of pile in liquefaction-induced lateral spreading ground were derived and implemented into a finite difference program.Based on the monotonic loading tests on saturated sand after liquefaction,the liquefaction lateral deformation of the site where group piles are located was predicted.The effects of lateral ground deformation after liquefaction on a group of pile foundations were studied using the fmite difference program mentioned above,and the failure mechanism of group piles in liquefaction-induced lateral spreading ground was obtained.The applicability of the program was preliminarily verified.The results show that the bending moments at the interfaces between liquefied and non-liquefied soil layers are larger than those at the pile's top when the pile's top is embedded.The value of the additional static bending moment is larger than the peak dynamic bending moment during the earthquake,so in the pile foundation design,more than the superstructure's dynamics should be considered and the effect of lateral ground deformation on pile foundations cannot be neglected.展开更多
The effect of vertical wind shear(VWS)directions on the change in western North Pacific tropical cyclone(TC)intensity is revisited in this study.Results show that the differences in the correlations between VWS in dif...The effect of vertical wind shear(VWS)directions on the change in western North Pacific tropical cyclone(TC)intensity is revisited in this study.Results show that the differences in the correlations between VWS in different orientations and the change in TC nondimensional intensity highly diminish,although slight differences are still present.The subtle differences in the correlations are likely associated with different synoptic-scale patterns at upper and lower levels.This result suggests that,in addition to thermodynamic effects,dynamic roles of the synoptic-scale patterns associated with the VWS should also be taken into account when the authors examine how VWS in different directions affects TC intensity change.展开更多
Based on the polarization analysis of teleseismic data,SKS (SKKS) fast-wave directions and delay times between fast and slow shear waves were determined for each of the 111 seismic stations from both permanent and tem...Based on the polarization analysis of teleseismic data,SKS (SKKS) fast-wave directions and delay times between fast and slow shear waves were determined for each of the 111 seismic stations from both permanent and temporary broadband seismograph networks deployed in the Ordos Block and its margins.Both the Silver and Chan and stacking analysis methods were used.In this way,an image of upper mantle anisotropy in the Ordos Block and its margins was acquired.In the western and northern margins of the Ordos Block,the fast-wave directions are consistently NW-SE.The fast-wave directions are mainly NWW-SEE and EW in the southern margin of the Ordos Block.In the eastern margin of the Ordos Block,the fast-wave directions are generally EW,although some run NEE-SWW or NWW-SEE.In the Ordos Block,the fast-wave directions trend near N-S in the north,but switch to near EW in the south.The delay time between fast and slow waves falls into the interval 0.48-1.50 s,and the average delay time at the stations in the Ordos Block is less than that in its margins.We suggest that the anisotropy of the stable Ordos Block is mainly caused by "fossil" anisotropy frozen in the ancient North China Craton.The NE-trending push of the northeastern margin of the Tibetan Plateau has caused NW-SE-trending lithospheric extension in the western and northern margins of the Ordos Block,and made the upper mantle flow southeastwards.This in turn has resulted in the alignment of the upper mantle peridotite lattice with the direction of material deformation.In the southern margin of the Ordos Block,the collision between the North China and Yangtze blocks resulted in the fast-wave direction running parallel to the collision boundary and the Qinling Orogen.Combining this with the APM and velocity structure of the Qinling Orogen,we propose that eastward-directed asthenospheric-mantle channel flow may have occurred beneath the Qinling Orogen.In the eastern margin of the Ordos Block,the complex anisotropic characteristics of the Fenhe Graben and Taihang Orogen may be caused by the interaction of western Pacific Plate subduction,regional extensional tectonics,and the orogeny.For station YCI,the apparent splitting parameters (the fast-wave directions range from 45° to 106° and the delay times range from 0.6 to 1.5 s) exhibit systematic variations as a function of incoming polarization with a periodicity of π/2.This variation can be best explained by a two-layer anisotropic model (φlower=132°,δtlower=0.8 s,φupper=83°,δtupper=0.5 s).The upper layer anisotropy beneath station YCI can again be attributed to "fossil" anisotropy frozen in the ancient North China Craton.The lower layer anisotropy is affected by the tectonic activity of the western Ordos Block.The NW-SE trending extension caused by the NE trending push of the northeastern margin of the Tibetan Plateau affected the deformation of the lower anisotropic layer beneath station YCI.By comparing the fast-wave directions with GPS velocity directions,we see that the crust and upper mantle possibly have vertically coherent deformation in the margins of the Ordos Block,whereas the internal deformation characteristics of the Ordos Block are complex and require further study.展开更多
T-tym phocyte migration under flow is critical for immune responses, but the mechanisms by which flow modulates the migratory beha- viors of T-lymphocytes remain unclear. Human peripheral blood T-lymphocytes (PBTLs)...T-tym phocyte migration under flow is critical for immune responses, but the mechanisms by which flow modulates the migratory beha- viors of T-lymphocytes remain unclear. Human peripheral blood T-lymphocytes (PBTLs), when stimulated with phorboL 12-myristate 13-acetate (PMA), stretched their ceU bodies dramatically and moved alongthe flow direction. In contrast, stromal ceil-derived factor- lα-stimulated PBTI.s deformed and migrated in a random manner. Here we elucidated the molecular mechanisms underlying flow- induced directionality and deformation of PMA-stimulated PBTLs. PMA primed PBTLs for polarization under flow, with protein kinase C (PKC)-δ enriched in the leading edge, PKC-β1 in the microtubuie organizing center, and PKC-1311 in the uropod and peripheral region. PKC-δ regulated cell protrusions in the leading edge through Tiaml/Racl/caLmoduUn, whereas PKC-β regulated RhoA/Rho- associated kinase activity and microtubule stability to modulate uropod contractility and detachment. Our findings indicate that PKC-δ and -β coordinate in the cell Leading edge and uropod, respectively, to modu|ate the directionality and deformability of migratory T-Lymphocytes under flow.展开更多
Over the past 10 years, the number of broadband seismic stations in China has increased significantly. The broadband seismic records contain information about shear-wave splitting which plays an important role in reve...Over the past 10 years, the number of broadband seismic stations in China has increased significantly. The broadband seismic records contain information about shear-wave splitting which plays an important role in revealing the upper mantle anisotropy in the Chinese mainland. Based on teleseismic SKS and SKKS phases recorded in the seismic stations, we used the analytical method of minimum transverse energy to determine the fast wave polarization direction and delay time of shear-wave splitting. We also collected results of shear-wave splitting in China and the surrounding regions from previously published papers. From the combined dataset we formed a shear-wave splitting dataset containing 1020 parameter pairs. These splitting parameters re- veal the complexity of the upper mantle anisotropy image. Our statistical analysis indicates stronger upper mantle anisotropy in the Chinese mainland, with an average shear-wave time delay of 0,95 s; the anisotropy in the western region is slightly larger (1.01 s) than in the eastern region (0.92 s). On a larger scale, the SKS splitting and surface deformation data in the Tibetan Plateau and the Tianshan region jointly support the lithospheric deformation mode, i.e. the crust-lithospheric mantle coherent deformation. In eastern China, the average fast-wave direction is approximately parallel to the direction of the absolute plate motion; thus, the upper mantle anisotropy can be attributed to the asthenospheric flow. The area from the Ordos block to the Sichuan Basin in central China is the transition zone of deformation modes between the east and the west regions, where the anisotropy images are more complicated, exhibiting "fossil" anisotropy and/or two-layer anis^3trc^py. The c^llisi(3n between the Indian Plate and the Eurasian Plate is the main factor of upper mantle anisotropy in the western region of the Chinese mainland, while the upper mantle anisotropy in the eastern region is related to the subduction of the Pacific Plate and the Philippine Sea Plate beneath the Eurasian Plate.展开更多
For the transient behavior of a semiconductor device, the modified method of characteristics with alternating-direction finite element procedures for nonrectangular region is put forward. Some techniques, such as calc...For the transient behavior of a semiconductor device, the modified method of characteristics with alternating-direction finite element procedures for nonrectangular region is put forward. Some techniques, such as calculus of variations, isoparametric transformation,patch approximation, operator-splitting, characteristic method, symmetrical reflection,energy method, negative norm estimate and a prior estimates and techniques, are employed. In the nonrectangular region case, optimal order estimates in L^2 norm are derived for the error in the approximation solution. Thus the well-known theoretical problem has been thoroughly and completely solved.展开更多
文摘目的调节是人眼调节视力的过程,现有的调节理论对调节过程中悬韧带张力分配的解释存在分歧,由于成像技术的限制,尚无法验证其准确性。在接受囊外摘除术的眼睛中,不同的悬韧带张力分配对囊膜形态有较大影响且容易被在体观测。本研究结合有限元分析方法与眼部超声显微成像,探究悬韧带张力分配对无晶体基质囊膜形态的影响。方法建立接受囊外摘除术后的一系列囊膜有限元模型,设定前囊环切口直径在1.5~6.5 mm之间。模型受前部(AZ)、赤道部(EZ)和后部悬韧带(PZ)的共同作用。设定总悬韧带张力为0.75 m N时为非调节态,模拟两种调节过程中的悬韧带张力分配:(1)EZ上的力逐渐增大至30 m N,AZ和PZ上的合力减小至0 m N;(2)所有悬韧带上的力都减小至0 m N。分析不同悬韧带张力分配下囊膜的形态变化。结果当EZ上的力随着其他悬韧带合力的减小而增加时,后囊表现出向后弯曲,这与恒河猴的超声在体成像结果一致。后囊向后弯曲的程度与前囊切口大小及EZ张力大小呈正相关。当所有悬韧带张力都减小时,囊膜形变方向与在体观测结果相反。结论赤道悬韧带对调节态下的囊膜形态有主要影响,调节态下仅赤道悬韧带紧张的模式与真实情况更加接近,这与Schachar理论的描述一致。
基金the National Hi-Tech Research and Development Program of China(Grant No.2006AA09A101).
文摘The close relationship between the structure,evolution,and resources environment of the South China Sea is a current research focus and also a focal point of our study.In this paper,we use regional seismic sections to analyze the relationship between seismic facies and the structure and tectonic evolution of the northeastern South China Sea and propose new points about the structure and the direction of block(land mass) motion.First,the tectonic features are clear and can be divided into five different structural units which are both linked and independent of each other.Second,it doesn't matter if the South China Sea basin pattern is extensional,weakly compressive,or strongly compressive,the regional tectonic stress field is unified.For the first time we find that two shallow subduction zones are recognized in the seismic profiles.All the tectonic blocks have accordion-fold-style structures,converging in the east,and the South China Sea exhibits different stages of basin development:growth, maturity,end,and termination.The block subduction and regional block dip directions are all aligned with the regional stress field.
基金Project supported by Department of Science and Technology, India
文摘This paper presents some investigations on the effect of processing parameters on the emission of electromagnetic radiation (EMR) during plastic deformation and crack propagation in copper-zinc alloys. Timing of the EMR emissions, maximum stress during crack instability, stress-intensity factor, elastic strain energy release rate, maximum EMR amplitude, RMS value of EMR amplitude, EMR frequency and electromagnetic energy release rate were analysed for the effect of rolling directions at different percentage of zinc content in Cu-Zn alloy specimens. The same parameters were also analysed for 68-32 Cu-Zn alloy specimens at different annealing temperatures and at different angles 0, to the rolling direction. EMR emissions are observed to be highly anisotropic in nature. At θ=45° to 60°, marked changes in mechanical and electromagnetic parameters were observed. Specimens annealed at 500℃, just above the recrystallization temperature, and at 700℃, when grain-size growth is rapid, EMR responses have been found to have well-defined patterns.
基金Project(51109208)supported by the National Natural Science Foundation of ChinaProject(2013M531688)supported by the Postdoctoral Science Foundation of China+1 种基金Project(Z012009)supported by the Open Research Fund of State Key Laboratory of Geomechanics and Geotechnical Engineering(Institute of Rock and Soil Mechanics,Chinese Academy of Sciences)Project(CKSF2012054)supported by the Foundation of Changjiang River Scientific Research Institute,China
文摘The pile-soil system interaction computational model in liquefaction-induced lateral spreading ground was established by the finite difference numerical method.Considering an elastic-plastic subgrade reaction method,numerical methods involving finite difference approach of pile in liquefaction-induced lateral spreading ground were derived and implemented into a finite difference program.Based on the monotonic loading tests on saturated sand after liquefaction,the liquefaction lateral deformation of the site where group piles are located was predicted.The effects of lateral ground deformation after liquefaction on a group of pile foundations were studied using the fmite difference program mentioned above,and the failure mechanism of group piles in liquefaction-induced lateral spreading ground was obtained.The applicability of the program was preliminarily verified.The results show that the bending moments at the interfaces between liquefied and non-liquefied soil layers are larger than those at the pile's top when the pile's top is embedded.The value of the additional static bending moment is larger than the peak dynamic bending moment during the earthquake,so in the pile foundation design,more than the superstructure's dynamics should be considered and the effect of lateral ground deformation on pile foundations cannot be neglected.
基金This work was jointly supported by the National Key Research and Development Program of China[grant numbers 2018YFC1507103 and 2017YFC1501601]the Key Program of the Ministry of Science and Technology of China[grant number 2017YFE0107700]National Natural Science Foundation of China[grant numbers 41875054,41730961,41730960,and 41775065].
文摘The effect of vertical wind shear(VWS)directions on the change in western North Pacific tropical cyclone(TC)intensity is revisited in this study.Results show that the differences in the correlations between VWS in different orientations and the change in TC nondimensional intensity highly diminish,although slight differences are still present.The subtle differences in the correlations are likely associated with different synoptic-scale patterns at upper and lower levels.This result suggests that,in addition to thermodynamic effects,dynamic roles of the synoptic-scale patterns associated with the VWS should also be taken into account when the authors examine how VWS in different directions affects TC intensity change.
基金supported by National Natural Science Foundation of China (Grant Nos. 40904023 and 90914005)the Special Project for the Fundamental R & D of Institute of Geophysics,China Earthquake Administration (Grant Nos. DQJB06B06, DQJB10B16)the Special Program of the Ministry of Science and Technology of China (Grant No. 2006FY110100)
文摘Based on the polarization analysis of teleseismic data,SKS (SKKS) fast-wave directions and delay times between fast and slow shear waves were determined for each of the 111 seismic stations from both permanent and temporary broadband seismograph networks deployed in the Ordos Block and its margins.Both the Silver and Chan and stacking analysis methods were used.In this way,an image of upper mantle anisotropy in the Ordos Block and its margins was acquired.In the western and northern margins of the Ordos Block,the fast-wave directions are consistently NW-SE.The fast-wave directions are mainly NWW-SEE and EW in the southern margin of the Ordos Block.In the eastern margin of the Ordos Block,the fast-wave directions are generally EW,although some run NEE-SWW or NWW-SEE.In the Ordos Block,the fast-wave directions trend near N-S in the north,but switch to near EW in the south.The delay time between fast and slow waves falls into the interval 0.48-1.50 s,and the average delay time at the stations in the Ordos Block is less than that in its margins.We suggest that the anisotropy of the stable Ordos Block is mainly caused by "fossil" anisotropy frozen in the ancient North China Craton.The NE-trending push of the northeastern margin of the Tibetan Plateau has caused NW-SE-trending lithospheric extension in the western and northern margins of the Ordos Block,and made the upper mantle flow southeastwards.This in turn has resulted in the alignment of the upper mantle peridotite lattice with the direction of material deformation.In the southern margin of the Ordos Block,the collision between the North China and Yangtze blocks resulted in the fast-wave direction running parallel to the collision boundary and the Qinling Orogen.Combining this with the APM and velocity structure of the Qinling Orogen,we propose that eastward-directed asthenospheric-mantle channel flow may have occurred beneath the Qinling Orogen.In the eastern margin of the Ordos Block,the complex anisotropic characteristics of the Fenhe Graben and Taihang Orogen may be caused by the interaction of western Pacific Plate subduction,regional extensional tectonics,and the orogeny.For station YCI,the apparent splitting parameters (the fast-wave directions range from 45° to 106° and the delay times range from 0.6 to 1.5 s) exhibit systematic variations as a function of incoming polarization with a periodicity of π/2.This variation can be best explained by a two-layer anisotropic model (φlower=132°,δtlower=0.8 s,φupper=83°,δtupper=0.5 s).The upper layer anisotropy beneath station YCI can again be attributed to "fossil" anisotropy frozen in the ancient North China Craton.The lower layer anisotropy is affected by the tectonic activity of the western Ordos Block.The NW-SE trending extension caused by the NE trending push of the northeastern margin of the Tibetan Plateau affected the deformation of the lower anisotropic layer beneath station YCI.By comparing the fast-wave directions with GPS velocity directions,we see that the crust and upper mantle possibly have vertically coherent deformation in the margins of the Ordos Block,whereas the internal deformation characteristics of the Ordos Block are complex and require further study.
文摘T-tym phocyte migration under flow is critical for immune responses, but the mechanisms by which flow modulates the migratory beha- viors of T-lymphocytes remain unclear. Human peripheral blood T-lymphocytes (PBTLs), when stimulated with phorboL 12-myristate 13-acetate (PMA), stretched their ceU bodies dramatically and moved alongthe flow direction. In contrast, stromal ceil-derived factor- lα-stimulated PBTI.s deformed and migrated in a random manner. Here we elucidated the molecular mechanisms underlying flow- induced directionality and deformation of PMA-stimulated PBTLs. PMA primed PBTLs for polarization under flow, with protein kinase C (PKC)-δ enriched in the leading edge, PKC-β1 in the microtubuie organizing center, and PKC-1311 in the uropod and peripheral region. PKC-δ regulated cell protrusions in the leading edge through Tiaml/Racl/caLmoduUn, whereas PKC-β regulated RhoA/Rho- associated kinase activity and microtubule stability to modulate uropod contractility and detachment. Our findings indicate that PKC-δ and -β coordinate in the cell Leading edge and uropod, respectively, to modu|ate the directionality and deformability of migratory T-Lymphocytes under flow.
基金supported by the National Natural Science Foundation of China(Grants Nos.90914005,91014006,41174070)the Basic Pro-ject in the Ministry of Science and Technology(Grants No.2006FY1101100)
文摘Over the past 10 years, the number of broadband seismic stations in China has increased significantly. The broadband seismic records contain information about shear-wave splitting which plays an important role in revealing the upper mantle anisotropy in the Chinese mainland. Based on teleseismic SKS and SKKS phases recorded in the seismic stations, we used the analytical method of minimum transverse energy to determine the fast wave polarization direction and delay time of shear-wave splitting. We also collected results of shear-wave splitting in China and the surrounding regions from previously published papers. From the combined dataset we formed a shear-wave splitting dataset containing 1020 parameter pairs. These splitting parameters re- veal the complexity of the upper mantle anisotropy image. Our statistical analysis indicates stronger upper mantle anisotropy in the Chinese mainland, with an average shear-wave time delay of 0,95 s; the anisotropy in the western region is slightly larger (1.01 s) than in the eastern region (0.92 s). On a larger scale, the SKS splitting and surface deformation data in the Tibetan Plateau and the Tianshan region jointly support the lithospheric deformation mode, i.e. the crust-lithospheric mantle coherent deformation. In eastern China, the average fast-wave direction is approximately parallel to the direction of the absolute plate motion; thus, the upper mantle anisotropy can be attributed to the asthenospheric flow. The area from the Ordos block to the Sichuan Basin in central China is the transition zone of deformation modes between the east and the west regions, where the anisotropy images are more complicated, exhibiting "fossil" anisotropy and/or two-layer anis^3trc^py. The c^llisi(3n between the Indian Plate and the Eurasian Plate is the main factor of upper mantle anisotropy in the western region of the Chinese mainland, while the upper mantle anisotropy in the eastern region is related to the subduction of the Pacific Plate and the Philippine Sea Plate beneath the Eurasian Plate.
基金This research is supported by the Major State Basic Research Program of China (Grant No. 19990328), the National Tackling Key Problem Program, the National Science Foundation of China (Grant Nos. 10271066 and 10372052), the Doctorate Foundation of th
文摘For the transient behavior of a semiconductor device, the modified method of characteristics with alternating-direction finite element procedures for nonrectangular region is put forward. Some techniques, such as calculus of variations, isoparametric transformation,patch approximation, operator-splitting, characteristic method, symmetrical reflection,energy method, negative norm estimate and a prior estimates and techniques, are employed. In the nonrectangular region case, optimal order estimates in L^2 norm are derived for the error in the approximation solution. Thus the well-known theoretical problem has been thoroughly and completely solved.