Oceanic front, especially Kuroshio front, is an important phenomenon that is of great significance for scientific research, national economy and military uses. However, Kuroshio front to the east of Taiwan （KFETW in ...Oceanic front, especially Kuroshio front, is an important phenomenon that is of great significance for scientific research, national economy and military uses. However, Kuroshio front to the east of Taiwan （KFETW in brief） was rare investigated. In this study, reanalysis method is used to study the KFETW＇s temporal and spatial variability and frontogenesis mechanism. It is found that although surface thermal front to the east of Taiwan is not obvious, there is an all-year strong Kuroshio thermal front called KFETW under the surface. The KFETW is connected to the south section of Kuroshio front in the East China Sea （KFECS in brief） and distributes along the east coastline of Taiwan. The KFETW has multi-scale variation feature. It has significant seasonal signal, and its intensity and width reach their maximum in summer. By using the reanalysis results obtained from this study, frontogenesis and changing mechanisms of the KFETW are discussed. It is found that both the Kuroshio and up-welling to the east of Taiwan can affect this front, and the up-welling may be the predominant factor in KFETW＇s frontogenesis and maintenance mechanism.展开更多
BM-13 505 is a new type of thromboxane receptor antagonist developed firstabfoad and synthesized in our school.wita modife method recently。The resultS of our study showed that the occlusion time of carotid artery in ...BM-13 505 is a new type of thromboxane receptor antagonist developed firstabfoad and synthesized in our school.wita modife method recently。The resultS of our study showed that the occlusion time of carotid artery in experimental thrombosis rats was prolonged by BM-13505,0.45 and 0.23 mglkg iv fP<0.00 1 and <0.01 respectively).B·13505 2 mgjkg iv ef fectively prevented the cerebral thrombosis caused by AA 4 mg/kg in rats(P<0.01) BM-13505 10 mg/kg ip prevented the AA-induced pulmonary thrombosis in mice(P<0.01).Tail bleeding time of mice was prolonged by this dru.BM-13505 significantly inhibited the AA-induced rabbit platelet aggregation,with an IC￣(50) of0.17 μmol/L; ADp-and collagen-induced aggregations were not affected.TXB_2 level in platelets and that in mice plasma were decreased by BM-13505,but cAMP level inplatelets was not affected. BM-13505 may be possibly developed into a useful anti-platelet and anti-thromboti c drug。展开更多
基金supported by grants of the National Basic Research Program of China(No.2007CB816001)the National Natural Science Foundation of China (No.41030854,40906016 and 40906015)
文摘Oceanic front, especially Kuroshio front, is an important phenomenon that is of great significance for scientific research, national economy and military uses. However, Kuroshio front to the east of Taiwan （KFETW in brief） was rare investigated. In this study, reanalysis method is used to study the KFETW＇s temporal and spatial variability and frontogenesis mechanism. It is found that although surface thermal front to the east of Taiwan is not obvious, there is an all-year strong Kuroshio thermal front called KFETW under the surface. The KFETW is connected to the south section of Kuroshio front in the East China Sea （KFECS in brief） and distributes along the east coastline of Taiwan. The KFETW has multi-scale variation feature. It has significant seasonal signal, and its intensity and width reach their maximum in summer. By using the reanalysis results obtained from this study, frontogenesis and changing mechanisms of the KFETW are discussed. It is found that both the Kuroshio and up-welling to the east of Taiwan can affect this front, and the up-welling may be the predominant factor in KFETW＇s frontogenesis and maintenance mechanism.
文摘BM-13 505 is a new type of thromboxane receptor antagonist developed firstabfoad and synthesized in our school.wita modife method recently。The resultS of our study showed that the occlusion time of carotid artery in experimental thrombosis rats was prolonged by BM-13505,0.45 and 0.23 mglkg iv fP<0.00 1 and <0.01 respectively).B·13505 2 mgjkg iv ef fectively prevented the cerebral thrombosis caused by AA 4 mg/kg in rats(P<0.01) BM-13505 10 mg/kg ip prevented the AA-induced pulmonary thrombosis in mice(P<0.01).Tail bleeding time of mice was prolonged by this dru.BM-13505 significantly inhibited the AA-induced rabbit platelet aggregation,with an IC￣(50) of0.17 μmol/L; ADp-and collagen-induced aggregations were not affected.TXB_2 level in platelets and that in mice plasma were decreased by BM-13505,but cAMP level inplatelets was not affected. BM-13505 may be possibly developed into a useful anti-platelet and anti-thromboti c drug。
