OBJECTIVE The current retrospective study aims to evaluate the management of non-functioning the assessment of experience on pituitary macroadenoma through clinical, biochemical, radiological features, and treatment o...OBJECTIVE The current retrospective study aims to evaluate the management of non-functioning the assessment of experience on pituitary macroadenoma through clinical, biochemical, radiological features, and treatment outcome of patients, and to identify prognostic factors affecting progression-free survival （PFS）. METHODS Data of 55 patients macroadenoma presented to the with non-functioning pituitary Clinical Oncology and Nuclear Medicine department between 1998 and 2009 were investigated. RESULTS The most common symptom was visual disturbance （38.2%） followed by headache （27.3%）. The presence of male predominance was observed （1.4：1）. Ten patients received radio-therapy （RT） only. Extrasellar extension was the more common treatment. The overall response rate was 72.8% with completed response at 16.4%. Memory and intellectual sequelae were the most common late complications of treatment （14%）. The ten-year PFS was at 84.6%. PFS was found to be significantly better with higher dose of RT （up to 54 Gy）, treatment by both surgery and RT, absence of visual field defect, and tumor localized to sella, whereas it was not significantly affected by age and sex. CONCLUSION The data confirmed that the prevalence of mass effect and hypopituitarism in patients with non-functioning pituitary macroadenoma is elevated. Conventional external RT up to 54 Gy is safe and effective in controlling non-functioning pituitary macro- adenoma with tolerable and acceptable morbidity.展开更多
The subtitles are one of the added elements in the early film and television works, and subtitles can be added only when the pictures are poorly interpreted. Later, they gradually became the special effects of the var...The subtitles are one of the added elements in the early film and television works, and subtitles can be added only when the pictures are poorly interpreted. Later, they gradually became the special effects of the variety shows. According to the current information that the author retrieved, there are relatively fewer domestic theses on the researches on the subtitle design. Although the domestic and the foreign scholars have confirmed the status of the subtitles in the film and television works, so far there is no known special work on the subtitle design, and only a handful of the journal articles have been published. Most of the researches on the subtitles are also about the functional production, and few Focus on the subtitle design. The research on the subtitle design is still at the beginning and blank stage.展开更多
Remote sensing based land cover mapping at large scale is time consuming when using either supervised or unsupervised clas- sification approaches. This article used a fast clustering method---Clustering by Eigen Space...Remote sensing based land cover mapping at large scale is time consuming when using either supervised or unsupervised clas- sification approaches. This article used a fast clustering method---Clustering by Eigen Space Transformation （CBEST） to pro- duce a land cover map for China. Firstly, 508 Landsat TM scenes were collected and processed. Then, TM images were clus- tered by combining CBEST and K-means in each pre-defined ecological zone （50 in total for China）. Finally, the obtained clusters were visually interpreted as land cover types to complete a land cover map. Accuracy evaluation using 2159 test sam- pies indicates an overall accuracy of 71.7% and a Kappa coefficient of 0.64. Comparisons with two global land cover products （i.e., Finer Resolution Observation and Monitoring of Global Land Cover （FROM-GLC） and GlobCover 2009） also indicate that our land cover result using CBEST is superior in both land cover area estimation and visual effect for different land cover types.展开更多
文摘OBJECTIVE The current retrospective study aims to evaluate the management of non-functioning the assessment of experience on pituitary macroadenoma through clinical, biochemical, radiological features, and treatment outcome of patients, and to identify prognostic factors affecting progression-free survival （PFS）. METHODS Data of 55 patients macroadenoma presented to the with non-functioning pituitary Clinical Oncology and Nuclear Medicine department between 1998 and 2009 were investigated. RESULTS The most common symptom was visual disturbance （38.2%） followed by headache （27.3%）. The presence of male predominance was observed （1.4：1）. Ten patients received radio-therapy （RT） only. Extrasellar extension was the more common treatment. The overall response rate was 72.8% with completed response at 16.4%. Memory and intellectual sequelae were the most common late complications of treatment （14%）. The ten-year PFS was at 84.6%. PFS was found to be significantly better with higher dose of RT （up to 54 Gy）, treatment by both surgery and RT, absence of visual field defect, and tumor localized to sella, whereas it was not significantly affected by age and sex. CONCLUSION The data confirmed that the prevalence of mass effect and hypopituitarism in patients with non-functioning pituitary macroadenoma is elevated. Conventional external RT up to 54 Gy is safe and effective in controlling non-functioning pituitary macro- adenoma with tolerable and acceptable morbidity.
文摘The subtitles are one of the added elements in the early film and television works, and subtitles can be added only when the pictures are poorly interpreted. Later, they gradually became the special effects of the variety shows. According to the current information that the author retrieved, there are relatively fewer domestic theses on the researches on the subtitle design. Although the domestic and the foreign scholars have confirmed the status of the subtitles in the film and television works, so far there is no known special work on the subtitle design, and only a handful of the journal articles have been published. Most of the researches on the subtitles are also about the functional production, and few Focus on the subtitle design. The research on the subtitle design is still at the beginning and blank stage.
基金partially supported by the National High-tech R&D Program of China(Grant No.2009AA12200101)a research grant from Tsinghua University(Grant No.2012Z02287)
文摘Remote sensing based land cover mapping at large scale is time consuming when using either supervised or unsupervised clas- sification approaches. This article used a fast clustering method---Clustering by Eigen Space Transformation （CBEST） to pro- duce a land cover map for China. Firstly, 508 Landsat TM scenes were collected and processed. Then, TM images were clus- tered by combining CBEST and K-means in each pre-defined ecological zone （50 in total for China）. Finally, the obtained clusters were visually interpreted as land cover types to complete a land cover map. Accuracy evaluation using 2159 test sam- pies indicates an overall accuracy of 71.7% and a Kappa coefficient of 0.64. Comparisons with two global land cover products （i.e., Finer Resolution Observation and Monitoring of Global Land Cover （FROM-GLC） and GlobCover 2009） also indicate that our land cover result using CBEST is superior in both land cover area estimation and visual effect for different land cover types.
