Ultrastructural immunocytochemical characterization of human long-term bone marrow cultures has shown positive localization for growth factors on cell surface and on extracellular matrix(ECM).In some cases double-labe...Ultrastructural immunocytochemical characterization of human long-term bone marrow cultures has shown positive localization for growth factors on cell surface and on extracellular matrix(ECM).In some cases double-labelling indicated co-localization of growth factors and specific cell surface labels.Specific markers for endothelial cells and fibroblasts showed that growth factor(GM-CSF,G-CSF and b-FGF) were present at the surface of these cell types.Both scanning and transmission electron microscopy indicated intense labelling for growth factors on the extracellular matrix.Double-labelling of heparan sulphate proteoglycans and GM-CSF showed a co-localization of the labelling,which indicated the binding of growth factor to the extracellular matrix.展开更多
A brief review on suspended-core fibers for sensing applications is presented. A historical overview over the previous ten years about this special designed microstructure optical fiber is described. This fiber presen...A brief review on suspended-core fibers for sensing applications is presented. A historical overview over the previous ten years about this special designed microstructure optical fiber is described. This fiber presents attractive optical properties for chemical/biological or gas measurement, but it can be further explored for alternative sensing solutions, namely, in-fiber interferometers based on the suspended-core or suspended-multi-core fiber, for physical parameter monitoring.展开更多
文摘Ultrastructural immunocytochemical characterization of human long-term bone marrow cultures has shown positive localization for growth factors on cell surface and on extracellular matrix(ECM).In some cases double-labelling indicated co-localization of growth factors and specific cell surface labels.Specific markers for endothelial cells and fibroblasts showed that growth factor(GM-CSF,G-CSF and b-FGF) were present at the surface of these cell types.Both scanning and transmission electron microscopy indicated intense labelling for growth factors on the extracellular matrix.Double-labelling of heparan sulphate proteoglycans and GM-CSF showed a co-localization of the labelling,which indicated the binding of growth factor to the extracellular matrix.
文摘A brief review on suspended-core fibers for sensing applications is presented. A historical overview over the previous ten years about this special designed microstructure optical fiber is described. This fiber presents attractive optical properties for chemical/biological or gas measurement, but it can be further explored for alternative sensing solutions, namely, in-fiber interferometers based on the suspended-core or suspended-multi-core fiber, for physical parameter monitoring.