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慢性肾功能衰竭尿毒症期透析患者微营养状态和心理应激反应的研究
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作者 高辉 郑兰 方文燕 《中文科技期刊数据库(文摘版)医药卫生》 2024年第10期0041-0044,共4页
慢性肾功能衰竭尿毒症期透析患者微营养状态和心理应激反应的研究。方法 整理2023年1月至2023年12月收治的慢性肾功能衰竭尿毒症期透析患者80例,应用数字表法分为腹膜透析组、血液透析组,各40例。分析患者微营养状态和心理应激反应。结... 慢性肾功能衰竭尿毒症期透析患者微营养状态和心理应激反应的研究。方法 整理2023年1月至2023年12月收治的慢性肾功能衰竭尿毒症期透析患者80例,应用数字表法分为腹膜透析组、血液透析组,各40例。分析患者微营养状态和心理应激反应。结果 治疗后腹膜透析组MNA评分优于血液透析组(P<0.05);腹膜透析组肝肾功能、电解质、PTH、血常规优于血液透析组(P〈0.05);腹膜透析组SAS、MCMQ评分优于血液透析组(P<0.05)。结论 腹膜透析有利于降低患者营养不良风险,改善患者生化指标,并能减轻患者的心理应激。 展开更多
关键词 慢性肾功能衰竭 尿毒症期 微营养状态 心理应激反应
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不同渗透压中药结肠透析对CKD3~4期患者的微炎症-营养状态影响 被引量:12
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作者 覃祚莲 谢永祥 +1 位作者 孟立锋 史伟 《中国中西医结合肾病杂志》 2018年第10期879-882,共4页
目的:观察高、低不同渗透压结肠透析联合中药保留灌肠对慢性肾脏病(CKD) 3~4期微炎症-营养状态的影响。方法:将120例CKD3~4期患者随机分为治疗组62例和对照组58例,两组均给予常规治疗基础上,治疗组给予高渗透压(320 mosm/kg H_2O)透... 目的:观察高、低不同渗透压结肠透析联合中药保留灌肠对慢性肾脏病(CKD) 3~4期微炎症-营养状态的影响。方法:将120例CKD3~4期患者随机分为治疗组62例和对照组58例,两组均给予常规治疗基础上,治疗组给予高渗透压(320 mosm/kg H_2O)透析液结肠灌洗透析后再行低渗透压(280 mosm/kg H_2O)复方大黄净化液进行中药保留灌肠。对照组采用低渗透压(280 mosm/kg H_2O)透析液进行结肠灌洗透析后再以低渗透压(280 mosm/kg H_2O)中药复方大黄净化液保留灌肠结肠透析治疗,疗程为1个月。观察治疗前后血清Scr、BUN、Ccr、hs-CRP、IL-6、TNF-α、SOD、Hb、PA、Alb的改变。结果:两组治疗后IL-6、TNF-α、hsCRP、Scr、BUN均较治疗前明显下降(P <0. 01或P <0. 05),治疗后治疗组IL-6、TNF-α、hsCRP、Scr、BUN降低水平明显低于对照组(P <0. 01);两组治疗后SOD、Hb、PA、Alb、Ccr均较治疗前上升(P <0. 05),治疗后治疗组SOD、Hb、PA、Alb、Ccr升高水平明显高于对照组(P <0. 01或P <0. 05)。结论:高渗透恒温结肠透析治疗可以显著改善CKD患者的微炎症、抗氧化及营养状态,延缓肾功能进展,延长非透析治疗时间。是一种安全、有效且容易被患者接受的治疗方法,有一定的临床推广应用价值。 展开更多
关键词 高渗透压结肠透析 中药灌肠 CKD3~4期 炎症-营养状态
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中药结肠透析对非透析慢性肾衰竭患者微炎症-营养状态的影响 被引量:13
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作者 刘家生 《中医药临床杂志》 2012年第9期864-867,共4页
目的:观察中药结肠透析对非透析慢性肾衰竭患者微炎症-营养状态的影响。方法:将60例患者随机分为治疗组和对照组,各30例。2组均给予常规治疗,同时治疗组予中药结肠透析,而对照组仅予手工中药直肠灌肠,1个疗程2周,4个疗程观察疗效,治疗... 目的:观察中药结肠透析对非透析慢性肾衰竭患者微炎症-营养状态的影响。方法:将60例患者随机分为治疗组和对照组,各30例。2组均给予常规治疗,同时治疗组予中药结肠透析,而对照组仅予手工中药直肠灌肠,1个疗程2周,4个疗程观察疗效,治疗前后检测尿素氮(BUN)、血肌酐(Scr)、血尿酸(UA)、肾小球率过滤(GFR)、血红蛋白(Hb)、血清白蛋白(Alb)、前白蛋白(Pre-A)、超敏C反应蛋白(hs-CRP)载脂蛋白a(L(a))及中医证候积分值变化。结果:治疗组临床疾病有效率90.00%,优于对照组60.00%,有显著性差异(P<0.05);治疗组中医证候有效率90.00%,优于对照组63.33%,差异有非常显著性(P<0.01)。治疗后2组血浆hs-CRP、L(a)水平均有所下降,治疗组下降较对照组差异显著(P<0.05)。营养指标Hb、Alb、Pre-A的改善,治疗组亦优于对照组(P<0.05或P<0.01)。结论:中药结肠透析可改善慢性肾衰竭非透析患者的微炎症-营养状态。 展开更多
关键词 非透析慢性肾衰竭 炎症-营养状态 结肠透析 中药 生化指标 中医证候积分
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艾灸联合中药结肠透析对CKD3~5期非透析患者微炎症-营养状态的影响
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作者 覃志周 高洺杨 +2 位作者 韦银霞 兰家磊 韦浩 《中国医药指南》 2023年第13期127-129,133,共4页
目的观察艾灸联合中药结肠透析对CKD3~5期非透析患者微炎症-营养状态的影响。方法选取符合纳入标准的CKD3~5期非透析患者77例,采用随机数字表法将其分为对照组41例和观察组36例。对照组采用西医常规治疗,观察组在对照组治疗基础上加用... 目的观察艾灸联合中药结肠透析对CKD3~5期非透析患者微炎症-营养状态的影响。方法选取符合纳入标准的CKD3~5期非透析患者77例,采用随机数字表法将其分为对照组41例和观察组36例。对照组采用西医常规治疗,观察组在对照组治疗基础上加用艾灸联合中药结肠透析治疗。艾灸关元穴,频率为每周5次;中药结肠透析隔天1次,每周3次。1个疗程为4周,两组均连续治疗2个疗程。观察治疗前后血清hs-CRP、TNF-α、IL-6、Hb、PA、ALB的变化。结果两组治疗后血清Hb、PA、ALB较治疗前明显升高(P<0.05),且观察组升高幅度明显高于对照组,差异具有统计学意义(P<0.05)。两组治疗后血清hs-CRP、TNF-α、IL-6均较治疗前明显下降(P<0.05),且观察组下降幅度明显高于对照组,差异具统计学意义(P<0.05)。结论艾灸联合中药结肠透析能显著改善CKD3~5期非透析患者微炎症-营养状态,延缓肾功能进展,延长非透析治疗时间。 展开更多
关键词 艾灸 中药结肠透析 CKD3~5期 炎症-营养状态
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维持性血液透析患者营养不良-炎症综合征与生存质量的相关性研究 被引量:35
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作者 羊红儿 齐玲 +1 位作者 许金华 孔祥栋 《浙江医学》 CAS 2019年第19期2063-2066,共4页
目的探讨维持性血液透析(MHD)患者营养不良-炎症综合征(MICS)与生存质量的相关性。方法对120例MHD患者采用营养不良-炎症评分表(MIS)进行MICS评估,采用KDQOL-SFTM量表进行生存质量评估,同时检测患者血清白蛋白(Alb)、超敏C反应蛋白(hs-C... 目的探讨维持性血液透析(MHD)患者营养不良-炎症综合征(MICS)与生存质量的相关性。方法对120例MHD患者采用营养不良-炎症评分表(MIS)进行MICS评估,采用KDQOL-SFTM量表进行生存质量评估,同时检测患者血清白蛋白(Alb)、超敏C反应蛋白(hs-CRP)水平。结果本组患者MICS发生率为100.0%;根据MIS评分结果,轻度39例,中度41例,重度40例。重度组患者血清Alb水平明显低于轻中度组,hs-CRP水平明显高于轻中度组,差异均有统计学意义(均P<0.05)。在KDQOL-SFTM量表KDTA方面,重度组患者症状与不适、生活、睡眠状况、社交质量、认知功能评分及总分均低于轻中度组(均P<0.05);重度组与轻中度组患者负担、工作状况、社会支持、性功能、透析医务人员的鼓励、患者满意度评分比较,差异均无统计学意义(均P>0.05);在SF-36方面,重度组患者体能、体力致工作和生活受限、疼痛、精力状况、总体健康状况评分及总分均低于轻中度组(均P<0.05);重度组与轻中度组患者情感问题、情感对工作和生活的影响、社会功能评分比较,差异均无统计学意义(均P>0.05)。MIS评分与KDTA总分及症状与不适、认知功能、睡眠状况及SF-36总分、体能、体力致工作和生活受限、总体健康状况均呈负相关(均P<0.05)。结论MICS是MHD的常见并发症,与患者生存质量的关系密切。 展开更多
关键词 维持性血液透析 营养不良-炎症状态 生存质量
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The trophic state of lake water regulates spatial-temporal variations of bloom-forming Microcystis 被引量:2
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作者 李印霞 刘碧波 +1 位作者 刘帅霞 李敦海 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2017年第2期415-422,共8页
Although biomass variations in Microcystis and microcystin have been widely reported,few studies have addressed whether different trophic states of natural lake water affect the spatial-temporal variations in abundanc... Although biomass variations in Microcystis and microcystin have been widely reported,few studies have addressed whether different trophic states of natural lake water affect the spatial-temporal variations in abundances of microcystin-producing Microcystis in a given bloom.In this study,we used a harmful algal bloom in Chaohu Lake,eastern China,as an example to investigate the mutual relationship between different nutrient states and environmental factors,and the impact on Microcystis.Overall,cyanobacteria and Microcystis were more abundant in the middle and western parts of the lake under high nutrients levels,while in the eastern part,nutrient concentrations were low enough to limit biomass,and their fluctuations affected the contents of toxic Microcystis.Moreover,microcystin concentration was correlated positively to nutrient levels and Microcystis biomass during bloom developing in 2013 from June to August.Temporally,the cellular content of total microcystin was lowest when the bloom peaked in intensity.Our results suggest that lake eutrophication not only results in cyanobacterial blooms,but may also increase the proportion of toxic Microcystis species and their cell-bound MCs contents(i.e.microcystin cell quotas) under mild eutrophication.The present investigation provided molecular evidence for the selection of MC-producing and non-MC-producing genotypes.The current study provides new evidence advocating the monitoring of partitions of large lakes when studying cyanobacteria and toxin-contaminated freshwaters,which will be beneficial for both water agencies and water researchers. 展开更多
关键词 CYANOBACTERIA MICROCYSTIN MICROCYSTIS Chaohu Lake algal bloom
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Multi-micronutrient Fortified Beverage Delivered through the School-Based System Improved Iron Status and Test Scores of Children
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作者 Imelda Angeles-Agdeppa Clarita Reyes Magsadia 《Journal of Food Science and Engineering》 2015年第3期112-121,共10页
Fortifying commonly consumed foods and beverages offers a great opportunity of filling the nutrient gap between actual and the needed nutrient intakes of young children. Ready-to-drink beverage as a vehicle for fortif... Fortifying commonly consumed foods and beverages offers a great opportunity of filling the nutrient gap between actual and the needed nutrient intakes of young children. Ready-to-drink beverage as a vehicle for fortification is easy to administer, more consistent and least obstructive, because it can be consumed without further processing/cooking. This study aimed to evaluate the effectiveness of fortified beverage on the improving of iron status and school performance test of schoolchildren. About 5,000 schoolchildren aged 6-12 years old from 19 schools in Quirino province, Philippines were invited to participate in the study. Samples of 4,875 children with parental consent were screened for hemoglobin and serum ferritin levels. About 4,495 children had complete participation in the school performance test, which were developed and administered by school supervisors. Children were fed 200 mL ready-to-drink juice fortified with iron, zinc, lysine, vitamins A and C for 120 d. The beverage was delivered through the baseline. At end of the intervention, only 1,050 children had complete data set and the anemia rate reduced from 100% to 60%. Iron deficiency has increased insignificantly from 3.6% to 4.5%. Mean percentage of test scores increased significantly between base and end of the study: English (40% to 60%), math (35% to 58%) and science (32% to 58%). In conclusion, consumption of 200 mL fortified juice drink had contributed to the reduction of anemia and increased tests scores of children. 展开更多
关键词 ANEMIA IRON school performance cognition.
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