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肥胖人群微血管反应性的变化及运动干预 被引量:7
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作者 肖哲 周术锋 +2 位作者 朱欢 李锋 胡江平 《中国组织工程研究》 CAS 北大核心 2023年第26期4223-4230,共8页
背景:在肥胖的发生与发展过程中,微血管功能障碍是关键因素。有氧运动不仅是减脂降重的有效方式,且能提高肥胖人群的微血管功能,但也有研究指出,抗阻运动、有氧联合抗阻运动、高强度间歇性运动等也能提高肥胖人群微血管反应性。目的:总... 背景:在肥胖的发生与发展过程中,微血管功能障碍是关键因素。有氧运动不仅是减脂降重的有效方式,且能提高肥胖人群的微血管功能,但也有研究指出,抗阻运动、有氧联合抗阻运动、高强度间歇性运动等也能提高肥胖人群微血管反应性。目的:总结肥胖人群微血管反应性的变化特点以及不同运动方式对肥胖人群微血管反应性的干预效应、主要机制,为改善肥胖人群微血管功能提供理论依据。方法:以“肥胖、微循环、微血管、毛细血管、微血管反应性、微血管舒张、微血管血流量、运动、训练”为中文检索词;以“obesity,microcirculation,microvascular,capillary,microvascular reactivity,microvascular vasodilatation,microvascular blood flow,exercise,training”为英文检索词,分别在CNKI中国期刊全文数据库和PubMed数据库重点检索2000年1月至2022年8月的相关文献,最终纳入61篇文献进行综述。结果与结论:①静息状态下,肥胖人群微血管内皮细胞功能受损,导致微血管反应性下降,但当体内氧化应激、炎症反应不明显时,微血管反应性可能不发生显著改变。运动过程中尤其在大强度运动中肥胖人群微血管反应性明显下降,导致血流灌注不足。②持续6-12周、每周3-5次、运动强度为60%-80%最大心率的有氧运动能有效改善肥胖人群微血管反应性,但有氧运动改善肥胖人群微血管反应性的“剂量-效应”关系仍需进一步研究明确;持续6-12周、每周3次、运动强度为65%-80%1RM的有氧联合抗阻运动能有效改善肥胖人群微血管反应性,但仅以抗阻运动为干预方式时则需更长的干预时间;持续4-12周、每周两三次、运动强度为最大有氧运动强度及以上的高强度间歇性运动能改善肥胖人群微血管反应性,但由于相关研究较少,因此需进一步研究明确高强度间歇性运动对肥胖人群微血管反应性的干预效应。③调节NO/内皮素1水平以及不同组织血管内皮生长因子的表达可能是运动改善肥胖人群微血管反应性的主要机制。 展开更多
关键词 肥胖人群 微血管反应性 微血管血流量 运动干预 一氧化氮 内皮素 内皮细胞生长因子
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The influence of different methods of acupuncture on skin surface perfusion 被引量:3
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作者 黄涛 王瑞红 +4 位作者 张维波 韩彬 王广军 田宇瑛 张宇沁 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2012年第1期40-44,共5页
OBJECTIVE:To compare the effects on the body surface of different kinds of placebo/sham acupuncture with that of traditional needling sensation acupuncture.METHODS:Point Neiguan(PC 6) of 29 healthy subjects,19 males a... OBJECTIVE:To compare the effects on the body surface of different kinds of placebo/sham acupuncture with that of traditional needling sensation acupuncture.METHODS:Point Neiguan(PC 6) of 29 healthy subjects,19 males and 10 females,was stimulated with needling sensation,shallow,placebo and deep acupuncture at the non-acupoint.After stimulation with different methods of acupuncture,the change in perfusion of the micrangium in the skin surface around the elbow joint,with Point Quze(PC 3) as its center,was observed with laser Doppler blood-flow imaging.RESULTS:Judging from the absolute value of perfusion of the skin surface micrangium,several methods of acupuncture can cause change in blood flow.The ratio of blood-flow perfusion in the meridian area in and around Quze declined before and after needling insertion in needling sensation acupuncture and shallow acupuncture.This observation did not occur in placebo and non-acupoint acupuncture.Needling sensation acupuncture at an acupoint can relatively reduce the perfusion ofthe micrangium in the projective area of the meridian where the acupoint is located on the body surface(P<0.05),indicating the specificity of meridians.CONCLUSIONS:Stimulation of an acupoint or a point on the body surface with any type of acupuncture can cause change in blood flow in the skin near the needling point.However,the biological mechanism underlying this phenomenon needs to be further explored. 展开更多
关键词 Skin surface perfusion ACUPUNCTURE
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Correlation of the Cerebral Microvascular Blood Flow with Brain Temperature and Electro-Acupuncture Stimulation 被引量:4
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作者 张栋 李林 +3 位作者 马慧敏 叶翠飞 王淑友 陈丁生 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2010年第4期243-248,共6页
Objective:To investigate the relationship between the temperature and the microvascular blood flow of the cerebral cortex, and the influence of electro-acupuncture (EA) on the cortical microcirculation. Methods: High ... Objective:To investigate the relationship between the temperature and the microvascular blood flow of the cerebral cortex, and the influence of electro-acupuncture (EA) on the cortical microcirculation. Methods: High temperature spots on the anterior ectosylvian and low temperature spots on the posterior suprasylvian on the cortical surface of 20 cats were identified using cortical infrared thermography (CIT); the blood flow in the microcirculation on these spots was measured with laser-Doppler flowmetry. EA was given at Zusanli (ST 36) and changes in the blood flow in the cerebral cortex microcirculation were detected. Results: 1) The mean temperatures on the high (34.83±0.24°C) and low (32.28±0.27°C) temperature spots were significantly different (P<0.001); this was indicative of a temperature difference on the cortical surface; 2) The average blood flow in the microcirculation of the high (266.8±19.2 PU) and low (140.8±9.9 PU) temperature spots was significantly different (P<0.001). 3) On the cortical high temperature spots, the mean blood flow in the microcirculation significantly increased from 266.8±86.8 PU before EA, to 422.5±47.4 PU following 5 minutes of EA (58.35%; P<0.01), and 431.8±52.8 PU 5 minutes after ceasing EA (61.84%; P<0.01). 4) On the low temperature spots, there were no significant differences in blood flow following 5 minutes of EA (146.3±11.5 PU), and 5 minutes after ceasing EA (140.5±11.6 PU), when compared with that before acupuncture (140.8±9.9 PU; P>0.9). Conclusion: The high temperature spots of the cortex are active functional regions of neurons with higher blood flow and a stronger response to EA. EA induces a significant increase in blood flow in the high temperature spots of the cortex. 展开更多
关键词 cerebral cortex brain temperature micro-circulation perfusion electro-acupuncture infrared thermography laser-Doppler technique
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