德分考核在高校学生管理中的运用及探索

高校学生管理中执行学校的规章制度以及校规校纪,德分考核的实施将其要求具体化、分项考核、进行了综合评定。实行班级德分考核管理可以使高校中各班级工作开展有条不紊,提高班委工作效率及班级同学参加活动的积极性。

初中思品教师提高学生“德分”的有效途径探析

思想品德课教学最终目的是提高学生道德品质水平，即“德分”。作为思品教师要增加学生的道德“德分”，主要措施是：重“讲解”，提高学生“德知”高度；扬“德模”，增强学生“德情”强度；抓“督导”，磨砺学生“德意”韧度。

“德智双学分制”下大学生综合素质培养与评价机制的探索与实践

大学生综合素质培养是落实高校立德树人根本任务的需要,也是高等教育推进供给侧结构性改革的重要落脚点.其核心问题在于建立科学、规范的德智双学分制下大学生综合素质培养和评价机制,设计并实现大学生在校成长的量化评定,促使学生在满足自我基本发展的基础上实现个性成长,合理考核、评价学生,高效、优质配置教育资源.

Dissecting Causal Relationships Between Plasma Metabolites and Osteoporosis:A Bidirectional Mendelian Randomization Study

Objective To investigate the causal relationships between plasma metabolites and osteoporosis via Mendelian randomization(MR) analysis.Methods Bidirectional MR was used to analyze pooled data from different genome-wide association studies(GWAS). The causal effect of plasma metabolites on osteoporosis was estimated using the inverse variance weighted method, intersections of statistically significant metabolites obtained from different sources of osteoporosis-related GWAS aggregated data was determined, and then sensitivity analysis was performed on these metabolites. Heterogeneity between single nucleotide polymorphisms was evaluated by Cochran's Q test. Horizontal pleiotropy was assessed through the application of the MR-Egger intercept method and the MRPRESSO method. The causal effect of osteoporosis on plasma metabolites was also evaluated using the inverse variance weighted method. Additionally, pathway analysis was conducted to identify potential metabolic pathways involved in the regulation of osteoporosis.Results Primary analysis and sensitivity analysis showed that 77 and 61 plasma metabolites had a causal relationship with osteoporosis from the GWAS data in the GCST90038656 and GCST90044600 datasets, respectively. Five common metabolites were identified via intersection. X-13684 levels and the glucose-to-maltose ratio were negatively associated with osteoporosis, whereas glycoursodeoxycholate levels and arachidoylcarnitine(C20) levels were positively associated with osteoporosis(all P < 0.05). The relationship between X-11299 levels and osteoporosis showed contradictory results(all P < 0.05). Pathway analysis indicated that glycine, serine, and threonine metabolism, valine, leucine, and isoleucine biosynthesis, galactose metabolism, arginine biosynthesis, and starch and sucrose metabolism pathways were participated in the development of osteoporosis.Conclusion We found a causal relationship between plasma metabolites and osteoporosis. These results offer novel perspectives with important implications for targeted metabolite-focused interventions in the management of osteoporosis.

张载性命论的新架构及学术价值

张载是宋代理学家中讲论性命的重要代表人物。他在继承孟子"性善"论和"立命"论的同时,致力于自立新说,建构了自成系统的性命论。张载认为,性有本有末,本即"天地之性",末即"气质之性",不能本末倒置。他最早划分"德命"与"气命",强调以"德命"驾驭"气命"。张载还认为,"天地之性"对应于"德命",而"气质之性"则对应于"气命"。他进而认为,"成性"与"至命"的目标也是对应的,"成性"必以"天地之性"而不以"气质之性"为根据,"至命"必以"德命"而不以"气命"为目标。在此方向引导下,"成性"工夫与"至命"工夫各有其特色。张载性命论的价值在于,强调以"道德性命"驾驭人生方向,以先"穷理"后"尽性"的工夫实践提升自我,让生命不断成长。

张载命论三题

张载是宋代理学家中讲论性命的重要代表人物。他在继承孟子"立命"论的同时,致力于自立新说,为儒家建构了新的命论。我们可以把张载命论梳理为三个相关的论题:第一个论题是张载对儒家命论的贡献,第二个论题是张载命论的特色,第三个论题是张载"至命"工夫的原则。

The Factors Shaping Synonymous Codon Usage in the Genome of Burkholderia mallei

Burkholderia mallei is regarded as a potential biological weapon by the Centers for Disease Control and Prevention. In this study, the main factors shaping codon usage in the genome of B. mallei ATCC 23344 were firstly reported. The results showed that the primary trend in codon usage variation in the B. mallei is due to translational selection; while compositional mutation bias is relatively the weaker influence and the hydrophobicity of each protein and gene length are only the minor influences. At the same time, 21 codons defined firstly as ＇optimal codons＇ might provide more useful information for the expression of target genes and development of a vaccine to prevent glanders.

GAMES ANALYSIS OF INSURANCE PRICING UNDER CONSIDERING MORAL HAZARD

This paper first gives an explanation of moral hazard in the insurance field,and then offers a game theory model about insurance pricing according to the non zero sum game analysis between the insurer and the insured when moral hazard exists.On the basis of the game analysis,this paper also presents a lowest pricing formula and studies the cost of moral hazard simultaneously.

Analysis of radial basis function interpolation approach

The radial basis function （RBF） interpolation approach proposed by Freedman is used to solve inverse problems encountered in well-logging and other petrophysical issues. The approach is to predict petrophysical properties in the laboratory on the basis of physical rock datasets, which include the formation factor, viscosity, permeability, and molecular composition. However, this approach does not consider the effect of spatial distribution of the calibration data on the interpolation result. This study proposes a new RBF interpolation approach based on the Freedman＇s RBF interpolation approach, by which the unit basis functions are uniformly populated in the space domain. The inverse results of the two approaches are comparatively analyzed by using our datasets. We determine that although the interpolation effects of the two approaches are equivalent, the new approach is more flexible and beneficial for reducing the number of basis functions when the database is large, resulting in simplification of the interpolation function expression. However, the predicted results of the central data are not sufficiently satisfied when the data clusters are far apart.

High Resolution Crossed Molecular Beams Study on the F＋HD→HF＋D Reaction at Collision Energy of 8.19-18.98 kJ/mol

The crossed beams scattering dynamics of the F＋HD→HF＋D reaction have been studied at collision energies ranging from 8.19 k J/tool to 18.98 k J/tool using the high resolution H-atom Rydberg tagging time-of-flight method. Product rotational state-resolved differential cross sections have been measured. Most of the DF products are backward scattered at low collision energies and then gradually shift to the sideway as the collision energy increases. In addition to the backward and sideway scatterings, we have also observed the DF（v＇=4） product in the forward direction for the first time for this reaction. The forward scattering DF（v=4） product also increases with the collision energy. Angular and collision energy dependence of the product energy disposals in different degrees of freedom have been determined. Collision energy dependence of the vibrational branching ratios has also been examined. Possible dynamical origins of the forward scattering DF（v＇=4） products were discussed.

Photodissociation of HOD via the C1B1 State： OD/OH Branching Ratio and OD Bond Dissociation Energy

Photodissociation of jet-cooled HOD via the C state around 124 nm has been studied using the H（D）-atom Rydberg tagging time-of-flight technique. Rotational state resolved action spectrum and the product translational energy distribution spectra have been recorded for both D＋OH and H＋OD dissociation channels. Product channel OH/OD branching ratios for the individual C-X rotational transition have been determined. A comparison is also given with the B-X and A-X transitions. In addition, the dissociation energy of the OD bond in HOD has been determined accurately to be 41751.3±5 cm-1.

Fission and Fusion of Localized Coherent Structures for a Higher-Order Broer-Kaup System

Starting from a Backlund transformation and taking a special ansatz for the function f, we can obtain a much more generalexpression of solution that includes some variable separated functions for the higher-order Broer-Kaup system. From this expression, we investigate the interactions of localized coherent structures such as the multi-solitonic excitations and find the novel phenomenon that their interactions have non-elastic behavior because the fission/fusion may occur after the interaction of each localized coherent structure.

High Resolution Crossed Molecular Beams Study on the F＋HD→HF＋D Reaction at Collision Energy of 5.43-18.73 kJ/mol

The dynamics of F＋HD→HF＋D reaction has been studied at ten collision energies ranging from 5.43 kJ/mol to 18.73 kJ/mol using high-resolution H/D atom Rydberg tagging time-of-flight method. Product vibrational and rotational state-resolved differential cross sections have been determined. The intensity of the HF（v1=2） forward products decreases as the collision energy increases, suggesting that the resonance contribution is reduced as the collision energy increases. The forward peak of HF（vl=3） product has also been observed above the threshold of this product channel. Product energy disposals in different degrees of freedom have been analyzed. The collision energy dependence of the HF vibrational product branching was also determined. This work presents a comprehensive dynamic picture of this resonance mediated reaction in a wide collision energy regime, providing a good test ground for theoretical understandings of this interesting reaction at higher collision energies.

Study on the Multi-dimension Evaluation Index System of Agricultural Water Resources in Liaoning Province

[Objective] This study aimed to establish the multi-dimensional evaluation index system of agricultural water resources in Liaoning Province. [Method] Delphi method in conjunction with AHP method was adopted to establish the multi-dimensional evaluation index system of agricultural water resources in Liaoning Province, and all the indexes in each hierarchy were ranked overall according to their weights. [Result] There were three hierarchies in this index system, totally including 21 indexes, among which water resource exploitation and utilization rate, sewage treatment rate and utilization of available water resources were the three crucial factors influencing the sustainable development. [Conclusion] This evaluation index system can reflect the true sustainable situation of the agricultural water resources in Liaoning Province.

Pig Manure Systems in Germany and China and the Impact on Nutrient Flow

Germany and China use different stable systems for fattening pigs. Widespread systems in Germany are closed stables with slatted or partly slatted floor, which produce liquid manure （a mixture of urine, faeces, and cleaning water） whereas in China open stables with closed concrete floors are used with separate collection of faeces and urine. Based on data from literature and own analyses nutrient flows of both systems are calculated. The Chinese manure system or mechanized belt or V-shaped pit floor systems with faeces/urine separation are more effective to separate solids, nutrients, carbon, and heavy metal than mechanical separation from liquid manure. The separation rates can be up to 88% for the solids, 67% for nitrogen, 93% for phosphorus, 60% for potassium, 94% for magnesium, 97% for cupper, and 98% for zinc. The faeces can be used for composting to produce a market product.

Ant colony ATTA clustering algorithm of rock mass structural plane in groups

Based on structural surface normal vector spherical distance and the pole stereographic projection Euclidean distance,two distance functions were established.The cluster analysis of structure surface was conducted by the use of ATTA clustering methods based on ant colony piles,and Silhouette index was introduced to evaluate the clustering effect.The clustering analysis of the measured data of Sanshandao Gold Mine shows that ant colony ATTA-based clustering method does better than K-mean clustering analysis.Meanwhile,clustering results of ATTA method based on pole Euclidean distance and ATTA method based on normal vector spherical distance have a great consistence.The clustering results are most close to the pole isopycnic graph.It can efficiently realize grouping of structural plane and determination of the dominant structural surface direction.It is made up for the defects of subjectivity and inaccuracy in icon measurement approach and has great engineering value.

Simulated Annealing Study on Structures and Energetics of CO2 in Argon Clusters

The minimum-energy configurations and energetic properties of the ArN-CO2 （N=1-19） van der Waals clusters were investigated by a simulated annealing algorithm. A newly developed Ar-CO2 potential energy surface together with the Aziz Ar-Ar interaction potential was employed to construct the high dimensional potential functions by pairwise additive approximation. The global minimal conformations were optimized by sampling the glassy phase space with a circumspectively formulated annealing schedule. Unlike the lighter agg-CO2 clusters, the size-dependent structural and energetic characteristics of ArN-CO2 exhibit a different behavior. The dramatically variations with number of solvent were found for small clusters. After the completion of the first solvation shell at N=17, the clusters were evolved more smoothly.

地下建筑物室内疏散引导地图的构建

在大型建筑地下空间事故中逃生是涉及空间数据模型构建、空间路径化和疏散路径规划,综合建筑、人和灾情态势因素相互作用的复杂科学问题。针对目前已有的地下室内空间数据模型缺乏描述室内灾害事件、地理实体动态语义特征的情况,从地下建筑物功能和结构特征出发,从几何、语义和时态3个角度设计了一种突出灾情语义、面向地理实体对象的部件级地下建筑物室内时空语义数据模型,并形成物理数据库。在此基础上,结合约束德劳奈(Delaunay)三角形剖分的思想实现室内3维疏散引导地图的高效构建,为复杂地下建筑物灾害事件发生时室内空间的路网快速构建和表达提供参考。实验结果表明,该方法构建的室内疏散引导地图可行、高效,可支撑后续疏散路径规划的研究。

A NOVEL MOLECULARLY IMPRINTED POLYMER:SYNTHESIS AND ADSORPTION BEHAVIOR OF GATIFLOXACIN

A kind of molecularly imprinted polymer (MIPs) with high selectivity was prepared using methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EDMA) as crosslinker and Gatifloxacin as template. The effect of various parameters such as volume of solvent, functional monomer dosage, crosslinker dosage and polymerization time were investigated. The selective binding experiment for substrates show that the affinity and selectivity for Gatifloxacin were higher than that for blank polymer. Scatchard analysis show that the MIPs recognized template with two kinds of binding sites. The dissociation constant Kd and maximum adsorption quantity Qmax of these two kinds of binding sites were calculated: Kd1 and Qmax1 of the binding sites with high affinity were 8.67×10-4 mol/L and 28.19μmol/g, while Kd2 and Qmax2 of the binding sites with low affinity were1.05×10-3 mol/L and 33.20μmol/g respectively.

Isolation and Complete Genomic Sequence Analysis of a New Sindbis-like Virus

The Sindbis-like virus was first discovered in China in 1986. Its complete genomic sequence consists of more than 11 000 bp encoding more than 3 700 amino acids. It contains a 5＇ non-transcriptional region （5＇-NTR） in a non-structural region, four non-structural proteins （nsP1, nsP2, nsP3, nsP4） regions, capsids in conserved and non-conserved regions and structural El, E2, E3, 6K regions and a 3＇ non-transcriptional region （3＇-NTR）. The Sindbis-IMB was isolated from the blood of a patient suspected to have encephalitis, and was followed by identification and passage. The virus RNA was extracted from virus supernatant in infected cells and the whole genome was divided into 12 fragments; RT-PCR was then performed to amplify the 12 fragments for complete sequencing. The results showed that the whole genomic sequence of Sindbis-IMB consists of 11 717 bp encoding 3 773 amino acids. Homology comparison with other Sindbis-like isolates demonstrated the highest similarity was the YN87448 with a variation of 1% strain isolated in Yunnan Province and the second highest to the SAAR86 strain with a variation of -1.2%. The nucleotide sequence variations were present in non-structural regions, resulting in amino acids K, E, N, R, H, and L in protein sequences in positions 230, 231,443,781, 1 582, and 1746 in the new isolation respectively. Furthermore, three additional amino acids-glutamic acid, serine and alanine-were noted in nsp4 terminus as compared to the YN87448 isolate