提高离心力卸料离心机离质量的一项简单有效措施

提高离心力卸料离心机离质量的一项简单有效措施郑州工学院王玉卿离心力卸料离心机不需要专门的卸料装置，利用物料受的离心力实现自动连续卸料，因此它具有结构简单、效率高、产量大、能耗低、制造容易、操作和维修费用低等特点。由于该机分离质量不稳定，它的应用范围受...

蘑菇保健饮料加工技术

蘑菇不仅营养丰富,而且药用价值也较高,所含多糖体和异蛋白有一定的抗癌活性,能抑制肿瘤的发生和发展。因此,用蘑菇为主料加工而成的饮料具有广阔的市场前景。

Experimental study and numerical analysis on bearing behaviors of super-long rock-socketed bored pile groups

A centrifuge modeling test and a three-dimensional finite element analysis（FEA）of super-long rock-socketed bored pile groups of the Tianxingzhou Bridge are proposed.Based on the similarity theory,different prototypical materials are simulated using different indicators in the centrifuge model.The silver sand,the shaft and the pile cap are simulated according to the natural density,the compressive stiffness and the bending stiffness,respectively.The finite element method（FEM）is implemented and analyzed in ANSYS,in which the stress field during the undisturbed soil stage,the boring stage,the concrete-casting stage and the curing stage are discussed in detail.Comparisons in terms of load-settlement,shaft axial force distribution and lateral friction between the numerical results and the test data are carried out to investigate the bearing behaviors of super-long rock-socketed bored pile groups under loading and unloading conditions.Results show that there is a good agreement between the centrifuge modeling tests and the FEM.In addition,the load distribution at the pile top is complicated,which is related to the stiffness of the cap,the corresponding assumptions and the analysis method.The shaft axial force first increases slightly with depth then decreases sharply,and the rate of decrease in rock is greater than that in sand and soil.

大蒜粉的加工方法

大蒜粉的加工方法１选料选用收获时叶黄秸枯、头大、瓣肉洁白、无病虫害、无机械破伤的大蒜作为原料，剔除不合格部分。２浸泡将选好的大蒜用冷水洗净，剥开分瓣，在冷水中浸泡１小时左右，搓去皮衣，捞起蒜瓣，沥干余水。３打浆将沥干的蒜瓣放入打浆机中，进行粉碎...

大蒜粉的制作

1.选料。选用收获时叶黄秸枯、头大、瓣肉洁白、无病虫害、无机械破损的大蒜。 2.浸泡。将大蒜用冷水洗净,剥开分瓣,在冷水中浸泡1小时左右,剔去皮衣,捞起蒜瓣,再除去带斑、病污的杂瓣蒜。要求皮衣去净,蒜瓣一色,沥干余水。 3.粉碎。将蒜瓣放在打浆机中或打粉机中打浆。打浆时蒜瓣加1/3净水,然后将蒜浆过滤(一般粗纱布即可),除去残余皮衣等杂物。

豌豆豆腐的加工方法

制作豆腐是豌豆综合利用的一条途径。下面介绍其加工方法。 1.工艺流程

Studies on Molecular Mechanism of Human Early Cardiogenesis Using the Drosophila as a Model System

Recently,some of the genetic mechanisms of heart specification have been elucidated in Drosophila .However,genes involved in early cardiogenesis of human remain to be identified.Since the pathways that regulate early cardiac fate determination are conserved between Drosophila and vertebrates,flies can be used as a model test system to explore the genetic basis of cardiogenesis in human.In this project,about 3000 reccieve lethal gene lines were produced by P or EMS mutagenesis.With staining of antibodies against heart precussor cells of Drosophila ,about 200 lines were observed to show heart phenotype.In pilot studies of their function with RNAi technique,the RNAi phenotypes of several genes tested were observed,which were very similar to that of their mutants,showing heart tube defects or no heart precursors formation.Taking advantage of the advanced genetic information available in the Drosophila and human systems,we have identified about 50 human transcripts homologous to the Drosophila heart related gene candidates.Northern blot analysis for some of the human candidates showed that several genes were expressed in both adult and early embryonic tissues,which may help in the evaluation of candidate genes for human cardiogenesis.Our further experiments with transgenic flies generated with wild type and mutant forms of these candidate genes to examine for defects in cardiogenesis or cardiac function are under way.The candidate genes producing cardiac specific defects suggestive of similarities to the heart disease syndromes can then be pursued further as likely disease gene candidates.Such an approach is likely to provide a dramatic reduction of possible candidate genes,or to screen and identify mutations that may generate the disease in human.

Direct calculation of acceleration field through homogeneous transformation for two-axis centrifuge

A precision centrifuge is an inertial navigation test equipment used for calibrating the characteristics of accelerometers with high overloading, and a two axis centrifuge can be used to generate either constant acceleration or harmonic acceleration. The moving trajectory equation about the origin of the accelerometer coordinate system in a two axis centrifuge was directly deduced through homogeneous transformation. The acceleration vector of the origin in accelerometer coordinate system was achieved by making the second derivative of this trajectory equation. The acceleration components were acquired by decomposing this acceleration vector along the three axes of the accelerometer coordinate system. The correctness of the homogeneous transformation was verified through vector analysis.

Atrial fibrosis： an obligatory component of arrhythmia mechanisms in atrial fibrillation？

Advances in clinical and fimdamental research, which have been promoted over last decades have led to a well- established understanding of atrial fibrillation （AF） as an epiphenomenon that despite similar manifestations may have different underlying mechanisms and thus require in- dividualized treatments. With rare exceptions of AF caused by mutations in genes coding ion channels in pa- tients with structurally normal atria, fibrotic replacement of atrial myocardium remains the comer stone of atrial pa- thology in patients with AF.

Heart failure in older adults：embracing complexity

Heart failure （HF）, particularly in the setting of preserved systolic function, disproportionately afflicts older individu- als and results in significant morbidity, mortality, and health care costs. In the United States, among the Medicare population （age 〉 65 years）, HF is among the leading cause of hospital admissions. Optimal care for older adults with HF requires knowledge of age-related physiologic changes, complex multi-organ, multi-dimensional syndromes, interdisciplinary teamwork and palliative/end of life care.

Molecular mechanisms of cardiac aging

Age-associated changes in cardiovascular structure/ function are implicated in the markedly increased risk for cardiovascular disease in older persons. Aging not only prolongs exposure to several other cardiovascular risks, but also leads to intrinsic cardiac changes, which reduces cardiac functional reserve, predisposes the heart to stress and contributes to increased cardiovascular mortality in the elderly. Intrinsic cardiac aging in the murine model closely recapitulates age-related cardiac changes in humans, includ- ing left ventricular hypertrophy, fibrosis and diastolic dysfunction. Cardiac aging in mice is accompanied by accumulation of mitochondrial protein oxidation, increased mitochondrial DNA mutations, increased mitochondrial biogenesis, as well as decreased cardiac SERCA2 protein. All of these age-related changes are significantly attenu- ated in mice overexpressing catalase targeted to mitochondria （mCAT）. These findings demonstrate the critical role of rnitochondrial reactive oxygen species （ROS） in cardiac ag ing and support the potential antioxidants to cardiac aging lar diseases. application of mitochondrial and age-related cardiovascular diseases.

Collapse mechanism of deep tunnels with three-centered arch cross section

The possible collapse of different circumstances is derived with the help of the limit analysis theory.Analytical equations related to collapsing mechanisms in deep tunnel with smooth three-centered arc cross sections are derived on the basis of Hoek-Brown failure criterion and upper bound limit analysis.The pore water pressure is considered in the analysis,as a work rate of external force.Numerical results about the shape of detaching curve and the weight of collapsing block per unit length corresponding to different parameters are obtained with the help of mathematical software.The shapes of collapsing block are drawn with respected to different parameters.Furthermore,the effects of different parameters on the shape of detaching curve and the weight of the collapsing block are discussed.

Insights into restrictive cardiomyopathy from clinical and animal studies

Cardiomyopathies are diseases that primarily affect the myocardium, leading to serious cardiac dysfunction and heart failure. Out of the three major categories of cardiomyopathies （hypertrophic, dilated and restrictive）, restrictive cardiomyopathy （RCM） is less common and also the least studied. However, the prognosis for RCM is poor as some patients dying in their childhood. The molecular mechanisms behind the disease development and progression are not very clear and the treatment of RCM is very difficult and often ineffective. In this article, we reviewed the recent progress in RCM research from the clinical studies and the translational studies done on diseased transgenic animal models. This will help for a better understanding of the mechanisms underlying the etiology and development of RCM and for the design of better treatments for the disease.

The study on the Psychological motivation of Costs Stickiness --Empirical Evidence from China

This paper studies Whether the managerial overconfidence have any impact on the Cost management （Characterized by the degree of the Costs Stickiness ） .Using the ample of the A-share listed companies between 2007-2011 in China, We document that SG＆A cost stickiness decreases in the degree of overconfidence. The further studies show the negative relation is more significant in the state-owned listed companies,which proved our speculation that the manager will cut expenses avoiding significant decline in performance when the sales decline in the state-owned listed company.

Short- and Long-term Therapeutic Efficacies of Intravenous Transplantation of Bone Marrow Stem Cells on Cardiac Function in Rats with Acute Myocardial Infarction:A Meta-analysis of Randomized Controlled Trials

Objective To investigate the short- and long-term therapeutic efficacies of intravenous transplantation of bone marrow stem cells(MSCs) in rats with experimental myocardial infarction by metaanalysis.Methods Randomized controlled trials were systematically searched from Pub Med,Science Citation Index(SCI),Chinese journal full-text database(CJFD) up to December 2014.While the experimental groups(MSCs groups) were injected MSCs intravenously,the control groups were injected Delubecco's minimum essential medium(DMEM) or phosphate buffered saline(PBS).Subgroup analysis for each outcome measure was performed for the observing time point after the transplantation of MSCs.Weighted mean differences(WMD) and 95% confidence intervals(CI) were calculated for outcome parameters including ejection fraction(EF) and fractional shortening(FS),which were measured by echocardiogram after intravenous injection and analyzed by Rev Man 5.2 and STATA 12.0.Results Data from 9 studies(190 rats) were included in the meta-analysis.As compared to the control groups,the cardiac function of the experimental groups were not improved at day 7(EF:WMD=0.08,95%CI-1.32 to 1.16,P>0.01; FS:WMD=-0.12,95%CI-0.90 to 0.65,P>0.01) until at day 14 after MSCs' transplantation(EF:WMD=10.79,95%CI 9.16 to 12.42,P<0.01; FS:WMD=11.34,95%CI 10.44 to 12.23,P<0.01),and it lasted 4 weeks or more after transplantation of MSCs(EF:WMD=13.94,95%CI 12.24 to 15.64,P<0.01; FS:WMD=9.64,95%CI 7.98 to 11.31,P<0.01).Conclusion The therapeutic efficacies of MSCs in rats with myocardid infarction become increasing apparent as time advances since 2 weeks after injection.

Exercise intolerance in heart failure with preserved ejection fraction： more than a heart problem

Heart failure （HF） with preserved ejection fraction （HFpEF） is the most common form of HF in older adults, and is increasing in preva- lence as the population ages. Furthermore, HFpEF is increasing out of proportion to HF with reduced EF （HFrEF）, and its prognosis is worsening while that of HFrEF is improving. Despite the importance of HFpEF, our understanding of its pathophysiology is incomplete, and optimal treatment remains largely undefined. A cardinal feature of HFpEF is reduced exercise tolerance, which correlates with symptoms as well as reduced quality of life. The traditional concepts of exercise limitations have focused on central dysfimction related to poor cardiac pump function. However, the mechanisms are not exclusive to the heart and lungs, and the understanding of the pathophysiology of this dis- ease has evolved. Substantial attention has focused on defining the central versus peripheral mechanisms underlying the reduced functional capacity and exercise tolerance among patients with HF. In fact, physical training can improve exercise tolerance via peripheral adaptive mechanisms even in the absence of favorable central hemodynamic function. In addition, the drug trials performed to date in HFpEF that have focused on influencing cardiovascular function have not improved exercise capacity. This suggests that peripheral limitations may play a significant role in HF limiting exercise tolerance, a hallmark feature of HFpEF.

The correlation and relationship of obesity and cancer: a possible research perspective

Recently, obesity is a well-recognized risk factor of type 2 diabetes and cardiovascular disease. There is more and more sufficient evidence that excess body weight is an avoidable cause of excess cancers including gastrointestinal, endometrial, esophageal adenocarcinoma, colorectal, postmenopausal breast, prostate, and renal cancers. The mechanism that obesity association with cancer is remains not well understood. There be some most studied hypothesized mechanisms such as, high levels of insulin and free levels of insulin-like growth factors （IGFs）, sex hormones, adipocytokines, intlammatory cytokines, c-Myc （or Myc） oncogenic transcription factor, obesity-induced hypoxia and Warburg effect, and so on. In the future, the potential mechanisms and conclusions in obesity associated with increased risk for developing cancer, and the underlying cellular and molecular mechanisms will be studied.

The Incentive Mechanism Research of Knowledge Workers

＂Knowledge workers＂ is the carrier of enterprise knowledge and technology and is undoubtedly the most important resource and core competence. How to effectively motivate such people create greater wealth for the enterprise has become the key problem of the era of knowledge economy. Based on the concept and characteristics of knowledge workers, this paper uses classical analysis framework of incentive theory; through quantitative and qualitative analysis, it points out the existing problems and puts forward solutions on the basis of full analysis of the present incentive situation.

Bifurcation and Stability Analysis of Time-Delayed Wheelset System under White Noise Excitation

Considering the impact of time delay in the lateral stiffness of the primary suspension and stochastic disturbances of equivalent conicity on the wheelset system, a stochastic time-delayed wheelset system is established. The wheelset system is transformed into a onedimensional Ito stochastic differential equation using central manifold and stochastic averaging methods. The analysis of the system's stochastic stability is conducted through the maximum Lyapunov exponent and singular boundary theory. The combination of the stationary probability density method and numerical simulation is employed to discuss the types and conditions of stochastic P-bifurcation in the wheelset system. The results indicate that changes in speed and time delay induce stochastic P-bifurcations in the wheelset system, while changes in noise intensity do not lead to stochastic P-bifurcations. Both time delay and equivalent conicity affect the critical speed of the wheelset system, and the critical speed gradually increases with the decrease of time delay and equivalent conicity.