目的:探讨胎儿心脏彩色多普勒超声(cardiac color doppler ultrasound,CCDU)在先天性心脏结构畸形中的应用观察。方法:选取2021年10月至2022年10月于涿鹿县中医院进行产前检查的孕妇842名,均通过胎儿CCDU的应用对心脏结构进行观察,同时...目的:探讨胎儿心脏彩色多普勒超声(cardiac color doppler ultrasound,CCDU)在先天性心脏结构畸形中的应用观察。方法:选取2021年10月至2022年10月于涿鹿县中医院进行产前检查的孕妇842名,均通过胎儿CCDU的应用对心脏结构进行观察,同时依据尸检结果、新生儿超声分析其诊断准确率、漏诊率、特异度、灵敏度。结果:新生儿超声和尸检结果诊断2心内膜垫缺损,2例室间隔缺损,1例右心室发育不良,2例法洛四联症,1例三尖瓣下移,1例单心腔,1例房间隔缺损,1例三房心,共11例;而胎儿CCDU诊断例数依次分别为2例、1例、1例、2例、1例、1例、1例、1例,共10例,胎儿CCDU的诊断效能指标:准确率:90.91%,漏诊率:9.09%,准确度:99.64%,特异度:99.76%、灵敏度:90.91%。结论:胎儿CCDU对先天性的心脏结构畸形有着较高的诊断价值,在使用CCDU进行临床诊断时,通过的不同切面筛查可以使得诊断效能显著提升,从而更好的辅助医生尽早干预胎儿缺陷,降低新生儿畸形率。展开更多
目的:观察沙库巴曲缬沙坦治疗持续性房颤的临床效果以及对心脏结构的影响。方法:随机选择2023年1月至2023年12月至我院进行治疗的持续性房颤患者110例,使用随机数字法将患者分为观察组和对照组各55例,分别予以沙库巴曲缬沙坦 + 胺碘酮...目的:观察沙库巴曲缬沙坦治疗持续性房颤的临床效果以及对心脏结构的影响。方法:随机选择2023年1月至2023年12月至我院进行治疗的持续性房颤患者110例,使用随机数字法将患者分为观察组和对照组各55例,分别予以沙库巴曲缬沙坦 + 胺碘酮治疗和单独应用胺碘酮治疗。比较两组患者治疗后14 d电复律比例和随访1年复发率、超声检查治疗前后左心室和左心房结构变化,以及血流动力学变化。结果:观察组患者14 d电复律治疗率、6个月和1年房颤复发率分别为20.00%、10.91%和27.27%,均低于对照组的49.49%、25.45%和58.18% (χ2 = 10.292, P = 0.001;χ2 = 3.911, P = 0.048;χ2 = 10.736, P = 0.001)。两组患者治疗前左心房内径(left anterior descending, LAD)、左心房容积(left atrial volume, LAV)、左心房容积指数(left atrial volume index, LAVI)、左心房存储应变(left atrial strain during reservoir phase, LASr)、左心室射血分数(left ventricular ejection fraction, LVEF)、舒张末期内径(left ventricular end diastolic diameter, LVEDD)、收缩末期内径(left ventricular end systolic diameter, LVESD)水平均无明显差异(P > 0.05),治疗1年后,两组患者上述指标与治疗前相比均有组内差异(P P P > 0.05),治疗后两组患者心率与治疗前相比均降低(P t = 8.651;P Objective: To observe the clinical effect of sackubactril valsartan in the treatment of persistent atrial fibrillation and its effect on cardiac structure. Methods: A total of 110 patients with persistent atrial fibrillation who were treated in our hospital from January 2023 to December 2023 were randomly selected and divided into observation group and control group by random number method, 55 patients in each group were treated with sacubactril valsartan + amiodarone or amiodarone alone. The proportion of electro cardioversion at 14 days after treatment, the recurrence rate at 1 year follow-up, the structural changes of left ventricle and left atrium before and after ultrasound, and the hemodynamic changes were compared between the two groups. Results: The 14 d electro cardioversion rate, 6-month and 1-year atrial fibrillation recurrence rates in the observation group were 20.00%, 10.91% and 27.27%, respectively, which were lower than those in the control group (49.49%, 25.45% and 58.18%, χ2 = 10.292, P = 0.001;χ2 = 3.911, P = 0.048;χ2 = 10.736, P = 0.001). left anterior descending (LAD), left atrial volume (LAV), left atrial volume index (left atrial volume index), left anterior descending (LAD), left atrial volume index (LAV) LAVI), left atrial strain during reservoir phase (LASr), left ventricular ejection fraction (left ventricular ejection fraction, LASr) LVEF), left ventricular end diastolic diameter (left ventricular end diastolic diameter, There were no significant differences in LVEDD and left ventricular end systolic diameter (LVESD) levels (P > 0.05). After 1 year of treatment, there were intra-group differences in the above indicators between the two groups compared with before treatment (P P P > 0.05), and the heart rate of the two groups after treatment was lower than that before treatment (P P < 0.001). Conclusion: Sakubactril valsartan is beneficial to the recovery of sinus rhythm in patients with persistent atrial fibrillation, and long-term use can help the recovery of heart structure and reduce heart rate, but does not affect the blood pressure of patients, which has good clinical application value.展开更多
文摘目的:探讨胎儿心脏彩色多普勒超声(cardiac color doppler ultrasound,CCDU)在先天性心脏结构畸形中的应用观察。方法:选取2021年10月至2022年10月于涿鹿县中医院进行产前检查的孕妇842名,均通过胎儿CCDU的应用对心脏结构进行观察,同时依据尸检结果、新生儿超声分析其诊断准确率、漏诊率、特异度、灵敏度。结果:新生儿超声和尸检结果诊断2心内膜垫缺损,2例室间隔缺损,1例右心室发育不良,2例法洛四联症,1例三尖瓣下移,1例单心腔,1例房间隔缺损,1例三房心,共11例;而胎儿CCDU诊断例数依次分别为2例、1例、1例、2例、1例、1例、1例、1例,共10例,胎儿CCDU的诊断效能指标:准确率:90.91%,漏诊率:9.09%,准确度:99.64%,特异度:99.76%、灵敏度:90.91%。结论:胎儿CCDU对先天性的心脏结构畸形有着较高的诊断价值,在使用CCDU进行临床诊断时,通过的不同切面筛查可以使得诊断效能显著提升,从而更好的辅助医生尽早干预胎儿缺陷,降低新生儿畸形率。
文摘目的:观察沙库巴曲缬沙坦治疗持续性房颤的临床效果以及对心脏结构的影响。方法:随机选择2023年1月至2023年12月至我院进行治疗的持续性房颤患者110例,使用随机数字法将患者分为观察组和对照组各55例,分别予以沙库巴曲缬沙坦 + 胺碘酮治疗和单独应用胺碘酮治疗。比较两组患者治疗后14 d电复律比例和随访1年复发率、超声检查治疗前后左心室和左心房结构变化,以及血流动力学变化。结果:观察组患者14 d电复律治疗率、6个月和1年房颤复发率分别为20.00%、10.91%和27.27%,均低于对照组的49.49%、25.45%和58.18% (χ2 = 10.292, P = 0.001;χ2 = 3.911, P = 0.048;χ2 = 10.736, P = 0.001)。两组患者治疗前左心房内径(left anterior descending, LAD)、左心房容积(left atrial volume, LAV)、左心房容积指数(left atrial volume index, LAVI)、左心房存储应变(left atrial strain during reservoir phase, LASr)、左心室射血分数(left ventricular ejection fraction, LVEF)、舒张末期内径(left ventricular end diastolic diameter, LVEDD)、收缩末期内径(left ventricular end systolic diameter, LVESD)水平均无明显差异(P > 0.05),治疗1年后,两组患者上述指标与治疗前相比均有组内差异(P P P > 0.05),治疗后两组患者心率与治疗前相比均降低(P t = 8.651;P Objective: To observe the clinical effect of sackubactril valsartan in the treatment of persistent atrial fibrillation and its effect on cardiac structure. Methods: A total of 110 patients with persistent atrial fibrillation who were treated in our hospital from January 2023 to December 2023 were randomly selected and divided into observation group and control group by random number method, 55 patients in each group were treated with sacubactril valsartan + amiodarone or amiodarone alone. The proportion of electro cardioversion at 14 days after treatment, the recurrence rate at 1 year follow-up, the structural changes of left ventricle and left atrium before and after ultrasound, and the hemodynamic changes were compared between the two groups. Results: The 14 d electro cardioversion rate, 6-month and 1-year atrial fibrillation recurrence rates in the observation group were 20.00%, 10.91% and 27.27%, respectively, which were lower than those in the control group (49.49%, 25.45% and 58.18%, χ2 = 10.292, P = 0.001;χ2 = 3.911, P = 0.048;χ2 = 10.736, P = 0.001). left anterior descending (LAD), left atrial volume (LAV), left atrial volume index (left atrial volume index), left anterior descending (LAD), left atrial volume index (LAV) LAVI), left atrial strain during reservoir phase (LASr), left ventricular ejection fraction (left ventricular ejection fraction, LASr) LVEF), left ventricular end diastolic diameter (left ventricular end diastolic diameter, There were no significant differences in LVEDD and left ventricular end systolic diameter (LVESD) levels (P > 0.05). After 1 year of treatment, there were intra-group differences in the above indicators between the two groups compared with before treatment (P P P > 0.05), and the heart rate of the two groups after treatment was lower than that before treatment (P P < 0.001). Conclusion: Sakubactril valsartan is beneficial to the recovery of sinus rhythm in patients with persistent atrial fibrillation, and long-term use can help the recovery of heart structure and reduce heart rate, but does not affect the blood pressure of patients, which has good clinical application value.
