To investigates the clinical sings and the pathology morphologic changes of the heart tissue of a case with the cardiac Wegener' s granulomatosis. Methods The clinical with was examined ECG and laboratory. The pat...To investigates the clinical sings and the pathology morphologic changes of the heart tissue of a case with the cardiac Wegener' s granulomatosis. Methods The clinical with was examined ECG and laboratory. The pathology samples were sectioned routine paraffin and stained with HE、PAS、AB-PAS and cellulose staining and observed with light microscope. Results The ECG was manifested acute myocardial infarction in the left lateral wall and the blood examination were of the heart, and the blood examination were manifested lift pedigree ferment of myocardium. The pathology sections were manifested necrosis large area perforation wall of the myocardial and became granuloma diffusible. Endocarditis, necrotic vesselitis and thrombus could be found and that the coronary is not embolism. Similar lesions could be found and alike to the heart in the left lung parenchyma and the peripheral zone of trachea and blood vessel. Histochemical examination with PAS and AB-PAS showed cryptococcus negative in the heart and lungs. Cellulose staining was positive reaction in the vascular wall. Antineutrophil cytoplasmic antibody (ANCA) was negative in the blood from the heart. Conclusion Cardiac Wegener's granulomatosis is rare. Clinical sings the ever so similar to acute myocardial infarction and that is not all but differentiation and prognosis and unfavorable of the ever cuch.展开更多
文摘To investigates the clinical sings and the pathology morphologic changes of the heart tissue of a case with the cardiac Wegener' s granulomatosis. Methods The clinical with was examined ECG and laboratory. The pathology samples were sectioned routine paraffin and stained with HE、PAS、AB-PAS and cellulose staining and observed with light microscope. Results The ECG was manifested acute myocardial infarction in the left lateral wall and the blood examination were of the heart, and the blood examination were manifested lift pedigree ferment of myocardium. The pathology sections were manifested necrosis large area perforation wall of the myocardial and became granuloma diffusible. Endocarditis, necrotic vesselitis and thrombus could be found and that the coronary is not embolism. Similar lesions could be found and alike to the heart in the left lung parenchyma and the peripheral zone of trachea and blood vessel. Histochemical examination with PAS and AB-PAS showed cryptococcus negative in the heart and lungs. Cellulose staining was positive reaction in the vascular wall. Antineutrophil cytoplasmic antibody (ANCA) was negative in the blood from the heart. Conclusion Cardiac Wegener's granulomatosis is rare. Clinical sings the ever so similar to acute myocardial infarction and that is not all but differentiation and prognosis and unfavorable of the ever cuch.
