目的分析探讨老年患者心血管冠状动脉介入治疗的临床治疗效果,为临床提供参考依据。方法选择我院收治的老年急性冠状动脉综合征患者作为研究对象,共100例,患者的收治时间在2014年2月至2015年3月,将患者分成实验组和对照组,实验组在冠状...目的分析探讨老年患者心血管冠状动脉介入治疗的临床治疗效果,为临床提供参考依据。方法选择我院收治的老年急性冠状动脉综合征患者作为研究对象,共100例,患者的收治时间在2014年2月至2015年3月,将患者分成实验组和对照组,实验组在冠状动脉介入治疗前给予患者他汀类药物治疗,对照组行介入治疗,对比分析两组的术前CRP、术后12 h CRP、术后24 h CRP及不良心脏事件发生率。结果实验组和对照组的术后CRP水平均高于手术前(P<0.05);但实验组的术后12 h CRP、术后24 h CRP低于对照组(P<0.05);实验组不良心脏事件发生率低于对照组(P<0.05),差异具有统计学意义。结论心血管冠状动脉介入治疗老年急性冠状动脉综合征可诱导或者加重局部炎性反应,冠状动脉介入治疗前给予患者他汀类药物治疗可减少心血管不良事件的发生,并减少由PCI术诱导的炎性反应。展开更多
Background The clinical significance of complete revascularization for ST segment elevation myocardial infarction （STEMI） pa- tients during admission is still debatable. Methods A total of 1406 STEMI patients from t...Background The clinical significance of complete revascularization for ST segment elevation myocardial infarction （STEMI） pa- tients during admission is still debatable. Methods A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention （PPCI） were analyzed. We used propensity score matching （PSM） to control differences of baseline characteristics between culprit only intervention （CP） and multivessel percutaneous coronary interventions （MP）, and between double vessel disease （DVD） and triple vessel disease （TVD）. The major adverse cardiac event （MACE） was analyzed for one year after discharge. Results TVD patients showed higher incidence of MACE （14.2% vs. 8.6%, P = 0.01）, any cause of revascularization （10.6% vs. 5.9%, P - 0.01）, and repeated PCI （9.5% vs. 5.7%, P = 0.02）, as compared to DVD patients during one year after discharge. MP reduced MACE effectively （7.3% vs. 13.8%, P = 0.03）, as compared to CP for one year, but all cause of death （1.6% vs. 3.2%, P= 0.38）, Ml （0.4% vs. 0.8%, P = 1.00）, and any cause ofrevascularization （5.3% vs. 9.7%, P = 0.09） were comparable in the two treatment groups. Conclusions STEMI patients with TVD showed higher rate of MACE, as compared to DVD MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.展开更多
文摘目的分析探讨老年患者心血管冠状动脉介入治疗的临床治疗效果,为临床提供参考依据。方法选择我院收治的老年急性冠状动脉综合征患者作为研究对象,共100例,患者的收治时间在2014年2月至2015年3月,将患者分成实验组和对照组,实验组在冠状动脉介入治疗前给予患者他汀类药物治疗,对照组行介入治疗,对比分析两组的术前CRP、术后12 h CRP、术后24 h CRP及不良心脏事件发生率。结果实验组和对照组的术后CRP水平均高于手术前(P<0.05);但实验组的术后12 h CRP、术后24 h CRP低于对照组(P<0.05);实验组不良心脏事件发生率低于对照组(P<0.05),差异具有统计学意义。结论心血管冠状动脉介入治疗老年急性冠状动脉综合征可诱导或者加重局部炎性反应,冠状动脉介入治疗前给予患者他汀类药物治疗可减少心血管不良事件的发生,并减少由PCI术诱导的炎性反应。
文摘Background The clinical significance of complete revascularization for ST segment elevation myocardial infarction （STEMI） pa- tients during admission is still debatable. Methods A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention （PPCI） were analyzed. We used propensity score matching （PSM） to control differences of baseline characteristics between culprit only intervention （CP） and multivessel percutaneous coronary interventions （MP）, and between double vessel disease （DVD） and triple vessel disease （TVD）. The major adverse cardiac event （MACE） was analyzed for one year after discharge. Results TVD patients showed higher incidence of MACE （14.2% vs. 8.6%, P = 0.01）, any cause of revascularization （10.6% vs. 5.9%, P - 0.01）, and repeated PCI （9.5% vs. 5.7%, P = 0.02）, as compared to DVD patients during one year after discharge. MP reduced MACE effectively （7.3% vs. 13.8%, P = 0.03）, as compared to CP for one year, but all cause of death （1.6% vs. 3.2%, P= 0.38）, Ml （0.4% vs. 0.8%, P = 1.00）, and any cause ofrevascularization （5.3% vs. 9.7%, P = 0.09） were comparable in the two treatment groups. Conclusions STEMI patients with TVD showed higher rate of MACE, as compared to DVD MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.
