目的:系统评价参松养心胶囊治疗快速性心律失常的疗效及安全性。方法:计算机检索PubMed、Web of Science、the Cochrane library、Embase、CBM、中国知网、万方、维普数据库中参松养心胶囊治疗快速性心律失常的随机对照试验,时限为建库...目的:系统评价参松养心胶囊治疗快速性心律失常的疗效及安全性。方法:计算机检索PubMed、Web of Science、the Cochrane library、Embase、CBM、中国知网、万方、维普数据库中参松养心胶囊治疗快速性心律失常的随机对照试验,时限为建库至2022年9月。由2名研究员独立筛选文献、提取数据并根据Cochrane手册对纳入研究的偏倚风险进行评价。采用RevMan 5.3软件进行数据分析,并绘制漏斗图对纳入研究的发表偏倚进行评价。结果:共纳入42项随机对照试验,包含3867例受试患者,参松养心胶囊联合常规西药治疗患者1952例,单纯常规西药治疗患者1915例。Meta分析结果显示:与单纯常规西药治疗相比,联用参松养心胶囊可明显改善临床总有效率(RR=1.18,95%CI=[1.13,1.22],P<0.00001)、心率(MD=-8.29,95%CI=[-12.29,-4.29],P<0.0001)、左心室射血分数(MD=4.90,95%CI=[3.48,6.33],P<0.00001)、左心舒张末期内径(MD=-6.94,95%CI=[-8.50,-5.38],P<0.00001)、左心收缩末期内径(MD=-4.62,95%CI=[-4.93,-4.31],P<0.00001)、6分钟步行试验(MD=72.36,95%CI=[27.39,117.34],P=0.002)、不良反应发生率(RR=0.65,95%CI=[0.49,0.86],P=0.002)。结论:当前证据显示,参松养心胶囊联合常规西药治疗快速性心律失常在改善临床总有效率、心率、左心室射血分数、左心舒张末期内径、左心收缩末期内径、6分钟步行试验疗效显著,且不良反应发生率低。但受纳入研究质量及数量的限制,今后仍需要开展能体现中医病证结合、辨证论治诊疗特色的大样本、多中心、随机、双盲、安慰剂平行对照试验进一步验证结论。展开更多
目的:基于“心胃同治”理论探讨快速性心律失常的临床治疗。方法:以“心胃同治”理论内涵着手,分析古今文献,论证出“心胃同治”理论与快速性心律失常相关的理论基础,总结出基于“心胃同治”理论治疗快速性心律失常的治疗原则与方法,并...目的:基于“心胃同治”理论探讨快速性心律失常的临床治疗。方法:以“心胃同治”理论内涵着手,分析古今文献,论证出“心胃同治”理论与快速性心律失常相关的理论基础,总结出基于“心胃同治”理论治疗快速性心律失常的治疗原则与方法,并附上一则医案予以验证。结果:快速性心律失常属于中医学“心悸”、“惊悸”、“怔忡”范畴,本病的发生发展多与痰火内扰和心的气血不足有关,在“心胃同治”理论指导下,通过清热化痰、补气养血原则调理脾胃,脾胃与心并治之法来治疗快速性心律失常。目前临床上鲜有通过此法治疗快速性心律失常的报道。所列举医案为痰火扰心所致快速性心律失常,通过“心胃同治”理论治疗,疗效显著。结论:以“心胃同治”法治疗快速性心律失常,兼顾临证加减,疗效显著,为医者提供治疗新思路。Objective: To explore the clinical treatment of tachyarrhythmia based on the theory of “cardio-stomach combined treatment”. Methods: Based on the theoretical connotation of “heart-stomach combined treatment”, the ancient and modern literature was analyzed, the theoretical basis related to “heart-stomach combined treatment” theory and tachyarrhythmia was demonstrated, and the therapeutic principles and methods based on "heart-stomach combined treatment" theory were summarized, and a medical case was attached for verification. Results: Tachyarrhythmia belongs to the category of TCM “palpitation”, “fright palpitation” and “palpitation”. The occurrence and development of tachyarrhythmia are mainly related to the internal disturbance of phlegm fire and the deficiency of qi and blood in the heart. Under the guidance of the theory of “heart-stomach combined treatment”, the spleen and stomach were regulated by the principle of clearing heat and eliminating phlegm, supplementing qi and nourishing blood. At present, there are few reports about tachyarrhythmia treated by this method in clinic. The medical cases listed are tachyarrhythmia caused by phlegm and fire disturbing the heart, which is treated with the theory of “heart and stomach combined treatment” and the curative effect is remarkable. Conclusion: The treatment of tachyarrhythmia by “cardio-stomach combined treatment”, taking into account clinical addition and subtraction, is effective and provides a new treatment idea for doctors.展开更多
文摘目的:基于“心胃同治”理论探讨快速性心律失常的临床治疗。方法:以“心胃同治”理论内涵着手,分析古今文献,论证出“心胃同治”理论与快速性心律失常相关的理论基础,总结出基于“心胃同治”理论治疗快速性心律失常的治疗原则与方法,并附上一则医案予以验证。结果:快速性心律失常属于中医学“心悸”、“惊悸”、“怔忡”范畴,本病的发生发展多与痰火内扰和心的气血不足有关,在“心胃同治”理论指导下,通过清热化痰、补气养血原则调理脾胃,脾胃与心并治之法来治疗快速性心律失常。目前临床上鲜有通过此法治疗快速性心律失常的报道。所列举医案为痰火扰心所致快速性心律失常,通过“心胃同治”理论治疗,疗效显著。结论:以“心胃同治”法治疗快速性心律失常,兼顾临证加减,疗效显著,为医者提供治疗新思路。Objective: To explore the clinical treatment of tachyarrhythmia based on the theory of “cardio-stomach combined treatment”. Methods: Based on the theoretical connotation of “heart-stomach combined treatment”, the ancient and modern literature was analyzed, the theoretical basis related to “heart-stomach combined treatment” theory and tachyarrhythmia was demonstrated, and the therapeutic principles and methods based on "heart-stomach combined treatment" theory were summarized, and a medical case was attached for verification. Results: Tachyarrhythmia belongs to the category of TCM “palpitation”, “fright palpitation” and “palpitation”. The occurrence and development of tachyarrhythmia are mainly related to the internal disturbance of phlegm fire and the deficiency of qi and blood in the heart. Under the guidance of the theory of “heart-stomach combined treatment”, the spleen and stomach were regulated by the principle of clearing heat and eliminating phlegm, supplementing qi and nourishing blood. At present, there are few reports about tachyarrhythmia treated by this method in clinic. The medical cases listed are tachyarrhythmia caused by phlegm and fire disturbing the heart, which is treated with the theory of “heart and stomach combined treatment” and the curative effect is remarkable. Conclusion: The treatment of tachyarrhythmia by “cardio-stomach combined treatment”, taking into account clinical addition and subtraction, is effective and provides a new treatment idea for doctors.
