目的探索缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)与母亲怀孕年龄及血清中高迁移率蛋白-1(high mobility group box protein 1,hmgb1)水平相关性,为有效预防和减少HIE的发生提供依据。方法随机选取山东大学第二医院于2012...目的探索缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)与母亲怀孕年龄及血清中高迁移率蛋白-1(high mobility group box protein 1,hmgb1)水平相关性,为有效预防和减少HIE的发生提供依据。方法随机选取山东大学第二医院于2012年3月—2014年3月收治的住院患者60例为病例组,同期60名正常新生儿为对照组。采用酶联免疫-双抗体夹心法测定病例组和对照组的血清hmgb1水平,并记录其孕母年龄,进行统计学分析。结果病例组母亲怀孕平均年龄较大,为(33.5±4.7)岁,高龄产妇的比例明显高于对照组;出生后2h内病例组各种程度HIE患儿(重、中、轻)的血清hmgb1水平均高于对照组,病情越严重,hmgb1在血清中的含量越高(174.88±9.12)ng/m L,且恢复正常的时间越长。结论 HIE与母亲怀孕年龄及血清中hmgb1水平相关,高龄产妇易导致HIE,hmgb1是早期临床检测HIE病情严重程度的指标之一。展开更多
Objective： Seat belt use during pregnancy reduces injury to the mother and her fetus. During recent years, the use of seat belts has been mandated by law in Iran. The purpose of this study was to determine the attitu...Objective： Seat belt use during pregnancy reduces injury to the mother and her fetus. During recent years, the use of seat belts has been mandated by law in Iran. The purpose of this study was to determine the attitudes and practices of pregnant women regarding seat belt use. Methods： In this cross-sectional study, we asked 335 pregnant women at a hospital-based prenatal care clinic on the use of safety belt before and during pregnancy. SPSS version 13.0 was used for data analysis. Results： The mean age of study subjects was 27.3 years±5.3 years with the median of 27 years. Compared with the seat belt use before pregnancy, no change was detectedin 48.7% of the women; seat belt use had increased in 17.5 % of them and decreased in 33.8 %. Eighty-one percent of women knew the correct placing ＆both lap belt and shoulder belt. Only 4% of women had received education on proper restraint use during pregnancy. Conclusions： The prevalence of seat belt use during pregnancy is lower than reports which are mostly from developed nations. The fact that about one-third of women have decreased their seat belt usage during pregnancy highlights the importance of education of mothers on this topic.展开更多
文摘目的探索缺氧缺血性脑病(hypoxic-ischemic encephalopathy,HIE)与母亲怀孕年龄及血清中高迁移率蛋白-1(high mobility group box protein 1,hmgb1)水平相关性,为有效预防和减少HIE的发生提供依据。方法随机选取山东大学第二医院于2012年3月—2014年3月收治的住院患者60例为病例组,同期60名正常新生儿为对照组。采用酶联免疫-双抗体夹心法测定病例组和对照组的血清hmgb1水平,并记录其孕母年龄,进行统计学分析。结果病例组母亲怀孕平均年龄较大,为(33.5±4.7)岁,高龄产妇的比例明显高于对照组;出生后2h内病例组各种程度HIE患儿(重、中、轻)的血清hmgb1水平均高于对照组,病情越严重,hmgb1在血清中的含量越高(174.88±9.12)ng/m L,且恢复正常的时间越长。结论 HIE与母亲怀孕年龄及血清中hmgb1水平相关,高龄产妇易导致HIE,hmgb1是早期临床检测HIE病情严重程度的指标之一。
文摘Objective： Seat belt use during pregnancy reduces injury to the mother and her fetus. During recent years, the use of seat belts has been mandated by law in Iran. The purpose of this study was to determine the attitudes and practices of pregnant women regarding seat belt use. Methods： In this cross-sectional study, we asked 335 pregnant women at a hospital-based prenatal care clinic on the use of safety belt before and during pregnancy. SPSS version 13.0 was used for data analysis. Results： The mean age of study subjects was 27.3 years±5.3 years with the median of 27 years. Compared with the seat belt use before pregnancy, no change was detectedin 48.7% of the women; seat belt use had increased in 17.5 % of them and decreased in 33.8 %. Eighty-one percent of women knew the correct placing ＆both lap belt and shoulder belt. Only 4% of women had received education on proper restraint use during pregnancy. Conclusions： The prevalence of seat belt use during pregnancy is lower than reports which are mostly from developed nations. The fact that about one-third of women have decreased their seat belt usage during pregnancy highlights the importance of education of mothers on this topic.
