Background: The Nnewly reported cases ofcongenital syphilis have been increaseding substantiallyover the past few years. To control the epidemic, a mu-nicipal program aimed at preventing mother-to-childtransmission of...Background: The Nnewly reported cases ofcongenital syphilis have been increaseding substantiallyover the past few years. To control the epidemic, a mu-nicipal program aimed at preventing mother-to-childtransmission of syphilis was introduced in July, 2001,which was designed aimed to screen all pregnant womenfor syphilis at their first visit to antenatal clinics or atadmission to hospitals in Shenzhen.Objectives: The aim of the study is tTo determine theprevalence of syphilis among women attending antenatalclinics and other medical institutions in Shenzhen andidentifies its patterns of infection. Methods: Upon giving informed consent, w Women whoattended antenatal care centers in Shenzhen from Janu-ary to December 2003 were included in this study subjectto obtaining informed consent. A blood sample was har-vested for syphilis screened for syphilising by using rapidplasma reagent test (RPR) and confirmed by TPHA forthose who were RPR positive. The women with pregnantsyphilispositive serology were systematically interviewedto obtain . During the interview, their demographicdetailsinformation,patterns of risk behaviors andother data. Data were collected andwere analyzedretrospectively.Results: Among Of 118,235 pregnant women surveyed,555 pregnant women were confirmed to have syphilis(prevalence of 4.69%), with a incidence of 4.69‰。 123women were excluded from the analysis because of in-complete medical records. Of 432 infected subjects withcomplete medical records, the average age was 26.8, witha range of 19 to 41. 7.41% (32/432) of them suffered fromprimary syphilis, 3.24% (14 /432) were ofhad secondary syphilis, and 89.35% (386/432) had latent syphilis. with-out any conspicuous clinical signs and symptoms.Conclusions: The prevalence of syphilis among the preg-nant women in our series was high and most of them wereasymptomatic. Screening for syphilis among pregnantwomen in Shenzhen is of importantce for the preventionof mother-to-child transmission of syphilis.展开更多
文摘Background: The Nnewly reported cases ofcongenital syphilis have been increaseding substantiallyover the past few years. To control the epidemic, a mu-nicipal program aimed at preventing mother-to-childtransmission of syphilis was introduced in July, 2001,which was designed aimed to screen all pregnant womenfor syphilis at their first visit to antenatal clinics or atadmission to hospitals in Shenzhen.Objectives: The aim of the study is tTo determine theprevalence of syphilis among women attending antenatalclinics and other medical institutions in Shenzhen andidentifies its patterns of infection. Methods: Upon giving informed consent, w Women whoattended antenatal care centers in Shenzhen from Janu-ary to December 2003 were included in this study subjectto obtaining informed consent. A blood sample was har-vested for syphilis screened for syphilising by using rapidplasma reagent test (RPR) and confirmed by TPHA forthose who were RPR positive. The women with pregnantsyphilispositive serology were systematically interviewedto obtain . During the interview, their demographicdetailsinformation,patterns of risk behaviors andother data. Data were collected andwere analyzedretrospectively.Results: Among Of 118,235 pregnant women surveyed,555 pregnant women were confirmed to have syphilis(prevalence of 4.69%), with a incidence of 4.69‰。 123women were excluded from the analysis because of in-complete medical records. Of 432 infected subjects withcomplete medical records, the average age was 26.8, witha range of 19 to 41. 7.41% (32/432) of them suffered fromprimary syphilis, 3.24% (14 /432) were ofhad secondary syphilis, and 89.35% (386/432) had latent syphilis. with-out any conspicuous clinical signs and symptoms.Conclusions: The prevalence of syphilis among the preg-nant women in our series was high and most of them wereasymptomatic. Screening for syphilis among pregnantwomen in Shenzhen is of importantce for the preventionof mother-to-child transmission of syphilis.