Elymus duthiei(Melderis)G.Singh,newly recorded from Xizang,China,is described and illustrated in detail.Morphologically,the species is similar to E.anthosachnoides(Keng)Á.Löve ex B.R.Lu and E.glaberrimus(Ken...Elymus duthiei(Melderis)G.Singh,newly recorded from Xizang,China,is described and illustrated in detail.Morphologically,the species is similar to E.anthosachnoides(Keng)Á.Löve ex B.R.Lu and E.glaberrimus(Keng&S.L.Chen)S.L.Chen but differs from the former in height and diameter of culms,number of nodes,width of leaf blades,and type of trichome and size of spikelets,and from the latter in distribution,height of culms,type of trichome of spikelets,and awn length.Detailed photo plates,descriptions,and distribution data are provided.展开更多
The aim of this study is to investigate the genetic diversity in 15 STRs (short tandem repeats) loci of four minorities in Guangxi Province and to probe into the genetic variation and relationships among these ethni...The aim of this study is to investigate the genetic diversity in 15 STRs (short tandem repeats) loci of four minorities in Guangxi Province and to probe into the genetic variation and relationships among these ethnic groups. Allele frequencies of 15 STR loci were collected from 766 unrelated Mulao, Maonan, Miao, and Yao ethnic individuals by PCR-STR and sequencing, and their allele-frequency distribution were compared with each other. The genetic parameters and genetic distances were calculated, and the phylogenetic tree was constructed. Based on the results from this study, 135, 134, 148, and 145 alleles and 424, 432, 445, and 436 genotypes for 15 STR loci were observed in the Mulao, Maonan, Miao, and Yao minorities, respectively. The average heterozygosity of all ethnic groups analyzed was above 0.7; the cumulative power of discrimination (DP), the probabilities of paternity exclusion (EPP), and the polymorphic information content (PIC) were greater than 0.99999. Comparison of the allele-frequency distribution indicated that there were significant differences at most loci between Maonan vs. Miao, Yao vs. other groups, but no distinct differences between Mulao vs. Maonan, and Mulao vs. Miao minorities. The NJ tree based on the genetic distance showed that the four minorities were separated into two groups. Mulao and Maonan were clustered into one group, whereas Miao and Yao into the other. Our results revealed that 15 STR loci of the four minorities possessed high genetic diversities. Therefore, the combination of these 15 STRs is a powerful tool for forensic individual identification and paternity investigation, as well as anthropologic and genetic researches. The genetic variation and relationships among the 4 populations revealed by 15 STRs are basically consistent with their linguistic culture and ethical history.展开更多
To reveal the genetic structures and relationships of the four ethnic populations from the maternal inheritance and explore the origins and migrations of nationalities, the genetic polymorphism of mtDNA in Dong, Gelao...To reveal the genetic structures and relationships of the four ethnic populations from the maternal inheritance and explore the origins and migrations of nationalities, the genetic polymorphism of mtDNA in Dong, Gelao, Tujia, and Yi populations from Guizhou was studied by direct sequencing of hypervariable segment Ⅰ (HVS Ⅰ ) and PCR-RFLP of coding region. Thirty-seven (sub-) haplogroups were identified in the classification tree of mtDNA haplogroups. Haplogroup distributions and principal component (PC) analysis showed that the Dong has high frequencies of south-prevalent haplogroups, which indicates that it is a typically southern population. The Yi harbors high frequencies of the south-prevalent and northern-prevalent haplogroups, which demonstrates that it inherits the maternal characteristics from both southern and northern populations. The Yi and Gelao cluster together, the reason for which might be that their ancestries frequently underwent gene exchanges and mixtures.展开更多
Objective To study the association of DTNBP1 gene with some symptom factors of schizophrenia.Methods A total of 285 unrelated schizophrenic individuals were recruited from December 2004 to January 2009 for genetic ana...Objective To study the association of DTNBP1 gene with some symptom factors of schizophrenia.Methods A total of 285 unrelated schizophrenic individuals were recruited from December 2004 to January 2009 for genetic analysis,and their symptom factors were assessed based on the Positive and Negative Syndrome Scale(PANSS).The quantitative trait test was performed by the UNPHASED program(version 3.0.12) to investigate the association between scored positive and negative symptoms and the single nucleotide polymorphisms(SNPs) in DTNBP1 gene.Results The quantitative trait test showed allelic association of rs909706 with the excitement symptom of schizophrenia(P<0.05,adjusted by 10 000 permutations),while the genotype C/G of rs2619539 with a negative symptom,lack of spontaneity and flow of conversation(P<0.05,adjusted by 10 000 permutations).Conclusion DTNBP1 variations are possibly associated with some symptoms of schizophrenia,which could partly explain the relationship between the susceptibility gene DTNBP1 and that disease.展开更多
Objective To explore the association between the three polymorphisms [ C825T, C1429T and G(-350)A] of the gene encoding the G protein beta 3 subunit (GNB3) and hypertension by performing a case-control study in th...Objective To explore the association between the three polymorphisms [ C825T, C1429T and G(-350)A] of the gene encoding the G protein beta 3 subunit (GNB3) and hypertension by performing a case-control study in the northern Han Chinese population. Methods We recnaited 731 hypertensive patients and 673 control subjects (the calculated power value was 〉 0.8). Genotyping was performed to identify C825T, C1429T and G(-350)A polymorphisms using the TaqMan assay. Comparisons of allelic and genotypic frequencies between cases and controls were made by using the chi-square test. Logistic regression analyses were performed to investigate the relationships between the three polymorphisms of GNB3 gene under different genetic models (additive, dominant and recessive models). Results The genotype dis- tribution and allele frequencies of C825T, C1429T and G(-350)A polymorphisms did not differ significantly between hypertensive patients and control subjects, either when the full sample was assessed, or when the sample was stratified by gender. No significant association was observed between C825T, C 1429T and G(-350)A polymorphisms and the risk of essential hypertension in any genetic model. Linkage dis- equilibrium was only detected between C825T and C 1429T polymorphisms. Haplotype analyses observed that none of the three estimated haplotypes significantly increased the risk of hypertension. Conclusions Our study suggested that the GNB3 gene polymorphisms [C825T, C 1429T and G(-350)A] were not significantly associated with essential hypertension in northern Han Chinese population.展开更多
AIM:To investigate the association between three tag single nucleotide polymorphisms (tagSNPs) in inter-feron regulatory factors (IRF3) and the genetic suscep-tibility to chronic hepatitis B virus (HBV) infection.METH...AIM:To investigate the association between three tag single nucleotide polymorphisms (tagSNPs) in inter-feron regulatory factors (IRF3) and the genetic suscep-tibility to chronic hepatitis B virus (HBV) infection.METHODS:We performed a case-control study of 985 Chinese cases of chronic HBV infection and 294 self-limiting HBV-infected individuals as controls.Three tagSNPs in IRF3 (rs10415576,rs2304204,rs2304206) were genotyped with the Multiplex SNaPshot technique.The genotype and allele frequencies were calculatedand analyzed.RESULTS:The three SNPs showed no significant geno-type/allele associations with chronic HBV infection.Overall allele P values were:rs10415576,P=0.0908,odds ratio (OR) [95% confidence interval (CI)]=1.1798 (0.9740-1.4291);rs2304204,P=0.5959,OR (95% CI)=1.0597 (0.8552-1.3133);rs2304206,P=0.8372,OR (95% CI)=1.0250 (0.8097-1.2976).Overall genotype P values were:rs10415576,P=0.2106;rs2304204,P=0.8458;rs2304206,P=0.8315.There were no statisti-cally significant differences between patients with chron-ic HBV infection and controls.Haplotypes generated by these three SNPs were also not significantly different between the two groups.CONCLUSION:The three tagSNPs of IRF3 are not asso-ciated with HBV infection in the Han Chinese population.展开更多
Taking Ningxia Hui Autonomous Region as an example, this research makes an empirical analysis on the factors influencing the migration activities of the research subject: the southern mountainous farmers who don't...Taking Ningxia Hui Autonomous Region as an example, this research makes an empirical analysis on the factors influencing the migration activities of the research subject: the southern mountainous farmers who don't emigrate and the farmers who immigrated in Hongsibao Development Zone. With Probit Model, the research shows that the age, educational degree, farming land per capita, number of school-aged children, vocational training experience and the quantity of gained information are all the factors which influence the farmers' emigration choice. However, the influential strength of the factors is different. The research aims to provide the government with more scientific evidences for its policies of promoting ecological migration and to encourage more poverty families to immigrate into the areas suitable for living.展开更多
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. According to the Rome m criteria, IBS is defined as recurrent abdominal pain or discomfort for at least 3 d per month during the previ...Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. According to the Rome m criteria, IBS is defined as recurrent abdominal pain or discomfort for at least 3 d per month during the previous 3 mo associated with two or more of the following symptoms: improvement with defecation, onset associated with a change in the frequency of stool and/or onset associated with a change in form or appearance of stool. There is growing evidence regarding the genetic contribution in IBS, however the precise etiology of IBS is still unknown. The evaluation of the genetic influence is based on twin studies, familial aggregation and genetic epidemiological investigations. Most studies showed a concordance for IBS significantly greater in monozygotic than in dizygotic twins. The majority of the studies have shown that familial aggregation may represent exposures to a similar environment, as well as the influence of genetic factors. Whereas no specific gene has been identified in association with IBS, recent studies have noticed the importance of polymorphisms in the promoter region of the serotonin reuptake transporter gene, G-protein beta 3 subunit gene (C825T), cholecystokinin receptor (CCKAR gene 779T〉C), and high-producer tumor necrosis factor genotype. Further studies are necessary to determine how genetic factors influence the clinical manifestations and therapeutical response in IBS patients.展开更多
Recent research has emphasized that attitude is key to language learners’learning outcomes.More specifically,language learners’feelings about languages and language learning may affect their study behavior and willi...Recent research has emphasized that attitude is key to language learners’learning outcomes.More specifically,language learners’feelings about languages and language learning may affect their study behavior and willingness to engage with a second or foreign language.Few studies on language attitudes have been conducted with ethnic minority groups in China.As such,influencing factors(e.g.,gender,language proficiency)have not gained sufficient attention.The present study aims to explore language attitudes,especially towards multilingualism,among members of the Li minority group in Hainan,China.First,we conceptualized and validated a questionnaire on attitudes towards multilingualism.Exploratory factor analysis and confirmatory factor analysis verified the survey’s validity.Then,we examined how selected sociodemographic variables(e.g.,gender and language proficiency)influenced students’attitudes towards multilingualism.Hierarchical regression was performed to ascertain the contribution of each predictor variable to learners’attitudes towards multilingualism.Results revealed no significant relationship between gender and language attitudes but found a significant impact of students’language proficiency level on their attitudes towards multilingualism.Implications for minority students’multilingual learning were discussed based on the findings.展开更多
The imbalance between supply and demand of Artemia cysts in China and around the world is increasing now.Salt lakes in Tibet may contribute to the solution of the problem.In Northern Tibet there are 26 saline lakes wh...The imbalance between supply and demand of Artemia cysts in China and around the world is increasing now.Salt lakes in Tibet may contribute to the solution of the problem.In Northern Tibet there are 26 saline lakes whose salinity and temperature may support Artemia survival at an altitude of 4 000–5 100 m.We found Artemia in 15 of these lakes.The saline lakes with Artemia populations mainly belong to the shallow basin lakes,and the majority of these lakes are small in area.The total area of lakes without Artemia is more than 1 000 km 2.Lake Dangxiong Co(Co means lake in Tibet) was chosen for the intentional introduction of Artemia sinica.In 2004,850 g of A.sinica cysts,originating from Qinghai,were introduced in the lake.Surveys in 2006–2014 showed that the average abundance of Artemia adults in the lake gradually increased from 20 ind./m 3 in 2006 to 1950 ind./m 3 in 2013.We assume that two subpopulations of A.sinica,separated by depth,may exist in the lake.The new Artemia population caused an increase in the number of species of phytoplankton and heterotrophic protozoa with a decrease of their total abundance.Water transparency also increased.Dominance in phytoplankton passed from cyanobacteria to diatoms.Changes occurred not only in the lake ecosystem;the number of water birds using the lakes also dramatically increased.Preliminary calculations showed that is it possible to harvest at least about 150 t cysts per year from the lake as well as 3.2 thousand tons of frozen or 350 t of dried biomass of adult Artemia.展开更多
In the process of folk custom development, ecological transformation is a normal phenomenon.This article will study the minority folk dance ecology transformation based on the perspective of social historical developm...In the process of folk custom development, ecological transformation is a normal phenomenon.This article will study the minority folk dance ecology transformation based on the perspective of social historical development.The author will discuss the native pattern and variable pattern for the development of the minority folk dance and analyze the positive influence and negative influence on minority dance at this stage. To address the problems in the development, the author puts forward some countermeasures and feasible suggestions for its future development.展开更多
AIM: To explore the associations of polymorphisms of lipopolysaccharide binding protein (LBP), cluster of differentiation 14 (CD14), toll-like receptor 4 (TLR-4), interleukin-6 (IL-6) and tumor necrosis factor α (TNF...AIM: To explore the associations of polymorphisms of lipopolysaccharide binding protein (LBP), cluster of differentiation 14 (CD14), toll-like receptor 4 (TLR-4), interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) with the colorectal carcinoma (CRC) risk in Han Chinese. METHODS: Polymorphisms of LBP (rs1739654, rs223 2596, rs2232618), CD14 (rs77083413, rs4914), TLR-4 (rs5030719), IL-6 (rs13306435) and TNF-α (rs35131721) were genotyped in 479 cases of sporadic colorectal carcinoma and 486 healthy controls of Han Chinese in a case-control study. Single-nucleotide polymorphisms (SNPs) between cases and controls were analyzed by unconditional logistic regression. RESULTS: GA and GG genotypes of LBP rs2232596 were associated with a significantly increased risk ofCRC [odds ratio (OR) = 1.51, 95% confidence interval (CI) 1.15-1.99, P = 0.003; OR = 2.49, 95% CI 1.16-5.38, P = 0.016, respectively]. A similar association was also observed for the CG genotype of CD14 rs4914 (OR= 1.69, 95% CI 1.20-2.36, P = 0.002). In addition, a combination of polymorphisms in LBP rs2232596 and CD14 rs4914 led to a 3.4-fold increased risk of CRC (OR = 3.44, 95% CI 1.94-6.10, P = 0.000). CONCLUSION: This study highlights the LBP rs2232596 and CD14 rs4914 polymorphisms as biomarkers for elevated CRC susceptibility in the Chinese Han population.展开更多
the more attention is paid to rights of minorities, the more grounds will be there for peaceful coexistence. This paper will first discuss theoretical and ideological bases of status and citizenship rights of minoriti...the more attention is paid to rights of minorities, the more grounds will be there for peaceful coexistence. This paper will first discuss theoretical and ideological bases of status and citizenship rights of minorities before focusing on "citizenship status of minorities" and "citizenship rights of minorities" from the viewpoint of Islam. Islam here means the collection of Quran, Prophet Muhammad's (S) Sunnah, and Imam Ali's (AS) conduct. The main question of this paper is "what status and rights have been considered by Islam for minorities to allow peaceful coexistence in a Muslim society?" "Minority" here includes both religious and non-religious minorities. "Rights" here means that part of "assets," "means," "political and social leverages," "privileges," and "conditions" which the majority is bound to by law, religious and common sense to provide for minorities. The word "status" here means to respect, serve, and provide suitable conditions which are provided just out of respect for human values not due to legal compulsion. In this paper, we will first discuss theoretical and ideological fundaments of minorities' rights before discussing "citizenship status of minorities" and "citizenship rights of minorities" from the viewpoint of Islam. By Islam, we mean Quran as well as Sunnah of Prophet Muhammad (S) and conduct of Imam All (AS).展开更多
In the process of folk custom development, ecological transformation is a normal phenomenon.This article will study the minority folk dance ecology transformation based on the perspective of social historical developm...In the process of folk custom development, ecological transformation is a normal phenomenon.This article will study the minority folk dance ecology transformation based on the perspective of social historical development.The author will discuss the native pattern and variable pattern for the development of the minority folk dance and analyze the positive influence and negative influence on minority dance at this stage. To address the problems in the development, the author puts forward some countermeasures and feasible suggestions for its future development展开更多
The Tu nationality (also called "Tu people" or "Tus" in the paper), one of the multiple ethnic minorities in the Hehuang Region (河湟地区) between Gansu (甘肃) and Qinghai (青海) Provinces in the northwest...The Tu nationality (also called "Tu people" or "Tus" in the paper), one of the multiple ethnic minorities in the Hehuang Region (河湟地区) between Gansu (甘肃) and Qinghai (青海) Provinces in the northwest China, has no written language of their own, but has already created the abundant and varied colorful literary genres. Since the 1980s, folktales, as the main literary product popular in the region, have received literary criticisms and reviews from scholars and researchers in China, based on the socialist realism dominant in China in the 20th century that emphasized more on contents, motifs and even ideological significance. So far, no breakthroughs have been made in their studies even if some young scholars have tried from the formalist viewpoints. Therefore, this paper attempts to make a morphological analysis of the Tus' folktales by adopting Propp's theories, trying to find out the morphological narrative model beneath the language level of the folktales. Through the studies, we can see that collective awareness bonded by kinship is more emphasized in Tus' culture, and almost all tales end with good defeating evil. Therefore, the studies of these folktales will help us deep understand Tus' psychological conditions and positive cultural life.展开更多
To help the poor and to develop tourism are two mportant problems in poverty-stricken areas. However, they were isolated for years.The PPET strategy was put forward in this paper based on PPT.The feasibility and the r...To help the poor and to develop tourism are two mportant problems in poverty-stricken areas. However, they were isolated for years.The PPET strategy was put forward in this paper based on PPT.The feasibility and the realistic meaning of the strategy in developing the ecotourism, overcoming poverty, and achieving prosperity of minority areas inwestern China are analyzed bytaking Xinlong county of Ganzi Tibetan Autonomous Prefecture in Sichuan Province as an example.展开更多
The ethnic areas of western Sichuan Province are characterized by complicated topography, seismic active zone, serious soil erosion, fragile eco-environment, low level of economy, and so on. Periphery regions and cent...The ethnic areas of western Sichuan Province are characterized by complicated topography, seismic active zone, serious soil erosion, fragile eco-environment, low level of economy, and so on. Periphery regions and central regions appear in western Sichuan Province. The socioconomic development in the central regions is at high level, whereas the ethnic areas are generally at lower level. Moreover. the deterioration of the eco-environment has seriously restricted the development of traditional industries in the ethnic areas, and it is necessary to develop environment-friendly and resource-saving industries. The ethnic areas of western Sichuan Province are rich in tourism resources, and have the potentiality of developing ecotourism. Advantages' of tourism resources in the ethnic areas should be made full use of and "comprehensive tourism " is the requirement of the characteristics and the status quo of the ethnic areas. The "comprehensive tourism development model " has the functions of ecotourism on the key industry. Based on the demands and the interaction among different industries, the model cart accelerate the development of related-industries, such as eco-agrieulture, eco-industry, eco-tertiary industry, and so on. Through implementing the comprehensive tourism model, we can fully utilize the advantages of ethnic areas, and promote the rapid and sustainable growth of regional economy, and also the harmonious development of economy, environment and society.展开更多
文摘Elymus duthiei(Melderis)G.Singh,newly recorded from Xizang,China,is described and illustrated in detail.Morphologically,the species is similar to E.anthosachnoides(Keng)Á.Löve ex B.R.Lu and E.glaberrimus(Keng&S.L.Chen)S.L.Chen but differs from the former in height and diameter of culms,number of nodes,width of leaf blades,and type of trichome and size of spikelets,and from the latter in distribution,height of culms,type of trichome of spikelets,and awn length.Detailed photo plates,descriptions,and distribution data are provided.
基金the National Natural Science Foundation of China (No. 30260044).
文摘The aim of this study is to investigate the genetic diversity in 15 STRs (short tandem repeats) loci of four minorities in Guangxi Province and to probe into the genetic variation and relationships among these ethnic groups. Allele frequencies of 15 STR loci were collected from 766 unrelated Mulao, Maonan, Miao, and Yao ethnic individuals by PCR-STR and sequencing, and their allele-frequency distribution were compared with each other. The genetic parameters and genetic distances were calculated, and the phylogenetic tree was constructed. Based on the results from this study, 135, 134, 148, and 145 alleles and 424, 432, 445, and 436 genotypes for 15 STR loci were observed in the Mulao, Maonan, Miao, and Yao minorities, respectively. The average heterozygosity of all ethnic groups analyzed was above 0.7; the cumulative power of discrimination (DP), the probabilities of paternity exclusion (EPP), and the polymorphic information content (PIC) were greater than 0.99999. Comparison of the allele-frequency distribution indicated that there were significant differences at most loci between Maonan vs. Miao, Yao vs. other groups, but no distinct differences between Mulao vs. Maonan, and Mulao vs. Miao minorities. The NJ tree based on the genetic distance showed that the four minorities were separated into two groups. Mulao and Maonan were clustered into one group, whereas Miao and Yao into the other. Our results revealed that 15 STR loci of the four minorities possessed high genetic diversities. Therefore, the combination of these 15 STRs is a powerful tool for forensic individual identification and paternity investigation, as well as anthropologic and genetic researches. The genetic variation and relationships among the 4 populations revealed by 15 STRs are basically consistent with their linguistic culture and ethical history.
基金This work was supported by the National Natural Science Foundation of China (No. 39560035).
文摘To reveal the genetic structures and relationships of the four ethnic populations from the maternal inheritance and explore the origins and migrations of nationalities, the genetic polymorphism of mtDNA in Dong, Gelao, Tujia, and Yi populations from Guizhou was studied by direct sequencing of hypervariable segment Ⅰ (HVS Ⅰ ) and PCR-RFLP of coding region. Thirty-seven (sub-) haplogroups were identified in the classification tree of mtDNA haplogroups. Haplogroup distributions and principal component (PC) analysis showed that the Dong has high frequencies of south-prevalent haplogroups, which indicates that it is a typically southern population. The Yi harbors high frequencies of the south-prevalent and northern-prevalent haplogroups, which demonstrates that it inherits the maternal characteristics from both southern and northern populations. The Yi and Gelao cluster together, the reason for which might be that their ancestries frequently underwent gene exchanges and mixtures.
基金Supported by National High Technology Research and Development Program of China (863 Program) (2006AA02A407)National Basic Research Program (973 Program) (2010CB529603)Beijing Natural Science Foundation (7102109)
文摘Objective To study the association of DTNBP1 gene with some symptom factors of schizophrenia.Methods A total of 285 unrelated schizophrenic individuals were recruited from December 2004 to January 2009 for genetic analysis,and their symptom factors were assessed based on the Positive and Negative Syndrome Scale(PANSS).The quantitative trait test was performed by the UNPHASED program(version 3.0.12) to investigate the association between scored positive and negative symptoms and the single nucleotide polymorphisms(SNPs) in DTNBP1 gene.Results The quantitative trait test showed allelic association of rs909706 with the excitement symptom of schizophrenia(P<0.05,adjusted by 10 000 permutations),while the genotype C/G of rs2619539 with a negative symptom,lack of spontaneity and flow of conversation(P<0.05,adjusted by 10 000 permutations).Conclusion DTNBP1 variations are possibly associated with some symptoms of schizophrenia,which could partly explain the relationship between the susceptibility gene DTNBP1 and that disease.
基金grants of the National High Technology Research and Development Program,grants of the National Eleventh Five-year Plan Program from the Ministry of Science and Technology of China,Beijing Natural Science Foundation
文摘Objective To explore the association between the three polymorphisms [ C825T, C1429T and G(-350)A] of the gene encoding the G protein beta 3 subunit (GNB3) and hypertension by performing a case-control study in the northern Han Chinese population. Methods We recnaited 731 hypertensive patients and 673 control subjects (the calculated power value was 〉 0.8). Genotyping was performed to identify C825T, C1429T and G(-350)A polymorphisms using the TaqMan assay. Comparisons of allelic and genotypic frequencies between cases and controls were made by using the chi-square test. Logistic regression analyses were performed to investigate the relationships between the three polymorphisms of GNB3 gene under different genetic models (additive, dominant and recessive models). Results The genotype dis- tribution and allele frequencies of C825T, C1429T and G(-350)A polymorphisms did not differ significantly between hypertensive patients and control subjects, either when the full sample was assessed, or when the sample was stratified by gender. No significant association was observed between C825T, C 1429T and G(-350)A polymorphisms and the risk of essential hypertension in any genetic model. Linkage dis- equilibrium was only detected between C825T and C 1429T polymorphisms. Haplotype analyses observed that none of the three estimated haplotypes significantly increased the risk of hypertension. Conclusions Our study suggested that the GNB3 gene polymorphisms [C825T, C 1429T and G(-350)A] were not significantly associated with essential hypertension in northern Han Chinese population.
基金Supported by Grants from the National Natural Science Foundation of China,No.81072342the National Pre-973 Program Projects,No. 2009CB526411
文摘AIM:To investigate the association between three tag single nucleotide polymorphisms (tagSNPs) in inter-feron regulatory factors (IRF3) and the genetic suscep-tibility to chronic hepatitis B virus (HBV) infection.METHODS:We performed a case-control study of 985 Chinese cases of chronic HBV infection and 294 self-limiting HBV-infected individuals as controls.Three tagSNPs in IRF3 (rs10415576,rs2304204,rs2304206) were genotyped with the Multiplex SNaPshot technique.The genotype and allele frequencies were calculatedand analyzed.RESULTS:The three SNPs showed no significant geno-type/allele associations with chronic HBV infection.Overall allele P values were:rs10415576,P=0.0908,odds ratio (OR) [95% confidence interval (CI)]=1.1798 (0.9740-1.4291);rs2304204,P=0.5959,OR (95% CI)=1.0597 (0.8552-1.3133);rs2304206,P=0.8372,OR (95% CI)=1.0250 (0.8097-1.2976).Overall genotype P values were:rs10415576,P=0.2106;rs2304204,P=0.8458;rs2304206,P=0.8315.There were no statisti-cally significant differences between patients with chron-ic HBV infection and controls.Haplotypes generated by these three SNPs were also not significantly different between the two groups.CONCLUSION:The three tagSNPs of IRF3 are not asso-ciated with HBV infection in the Han Chinese population.
基金supported by National Natural Science Fundation of China (Grant No.70763008)
文摘Taking Ningxia Hui Autonomous Region as an example, this research makes an empirical analysis on the factors influencing the migration activities of the research subject: the southern mountainous farmers who don't emigrate and the farmers who immigrated in Hongsibao Development Zone. With Probit Model, the research shows that the age, educational degree, farming land per capita, number of school-aged children, vocational training experience and the quantity of gained information are all the factors which influence the farmers' emigration choice. However, the influential strength of the factors is different. The research aims to provide the government with more scientific evidences for its policies of promoting ecological migration and to encourage more poverty families to immigrate into the areas suitable for living.
文摘Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. According to the Rome m criteria, IBS is defined as recurrent abdominal pain or discomfort for at least 3 d per month during the previous 3 mo associated with two or more of the following symptoms: improvement with defecation, onset associated with a change in the frequency of stool and/or onset associated with a change in form or appearance of stool. There is growing evidence regarding the genetic contribution in IBS, however the precise etiology of IBS is still unknown. The evaluation of the genetic influence is based on twin studies, familial aggregation and genetic epidemiological investigations. Most studies showed a concordance for IBS significantly greater in monozygotic than in dizygotic twins. The majority of the studies have shown that familial aggregation may represent exposures to a similar environment, as well as the influence of genetic factors. Whereas no specific gene has been identified in association with IBS, recent studies have noticed the importance of polymorphisms in the promoter region of the serotonin reuptake transporter gene, G-protein beta 3 subunit gene (C825T), cholecystokinin receptor (CCKAR gene 779T〉C), and high-producer tumor necrosis factor genotype. Further studies are necessary to determine how genetic factors influence the clinical manifestations and therapeutical response in IBS patients.
文摘Recent research has emphasized that attitude is key to language learners’learning outcomes.More specifically,language learners’feelings about languages and language learning may affect their study behavior and willingness to engage with a second or foreign language.Few studies on language attitudes have been conducted with ethnic minority groups in China.As such,influencing factors(e.g.,gender,language proficiency)have not gained sufficient attention.The present study aims to explore language attitudes,especially towards multilingualism,among members of the Li minority group in Hainan,China.First,we conceptualized and validated a questionnaire on attitudes towards multilingualism.Exploratory factor analysis and confirmatory factor analysis verified the survey’s validity.Then,we examined how selected sociodemographic variables(e.g.,gender and language proficiency)influenced students’attitudes towards multilingualism.Hierarchical regression was performed to ascertain the contribution of each predictor variable to learners’attitudes towards multilingualism.Results revealed no significant relationship between gender and language attitudes but found a significant impact of students’language proficiency level on their attitudes towards multilingualism.Implications for minority students’multilingual learning were discussed based on the findings.
基金Supported by the Special Fund for Public Welfare Land and Resources(No.201011001-4)the Project of China Geological Survey(No.1212011120982)
文摘The imbalance between supply and demand of Artemia cysts in China and around the world is increasing now.Salt lakes in Tibet may contribute to the solution of the problem.In Northern Tibet there are 26 saline lakes whose salinity and temperature may support Artemia survival at an altitude of 4 000–5 100 m.We found Artemia in 15 of these lakes.The saline lakes with Artemia populations mainly belong to the shallow basin lakes,and the majority of these lakes are small in area.The total area of lakes without Artemia is more than 1 000 km 2.Lake Dangxiong Co(Co means lake in Tibet) was chosen for the intentional introduction of Artemia sinica.In 2004,850 g of A.sinica cysts,originating from Qinghai,were introduced in the lake.Surveys in 2006–2014 showed that the average abundance of Artemia adults in the lake gradually increased from 20 ind./m 3 in 2006 to 1950 ind./m 3 in 2013.We assume that two subpopulations of A.sinica,separated by depth,may exist in the lake.The new Artemia population caused an increase in the number of species of phytoplankton and heterotrophic protozoa with a decrease of their total abundance.Water transparency also increased.Dominance in phytoplankton passed from cyanobacteria to diatoms.Changes occurred not only in the lake ecosystem;the number of water birds using the lakes also dramatically increased.Preliminary calculations showed that is it possible to harvest at least about 150 t cysts per year from the lake as well as 3.2 thousand tons of frozen or 350 t of dried biomass of adult Artemia.
文摘In the process of folk custom development, ecological transformation is a normal phenomenon.This article will study the minority folk dance ecology transformation based on the perspective of social historical development.The author will discuss the native pattern and variable pattern for the development of the minority folk dance and analyze the positive influence and negative influence on minority dance at this stage. To address the problems in the development, the author puts forward some countermeasures and feasible suggestions for its future development.
基金Supported by The Nationgal Natural Science Foundation of China,No.30571924
文摘AIM: To explore the associations of polymorphisms of lipopolysaccharide binding protein (LBP), cluster of differentiation 14 (CD14), toll-like receptor 4 (TLR-4), interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) with the colorectal carcinoma (CRC) risk in Han Chinese. METHODS: Polymorphisms of LBP (rs1739654, rs223 2596, rs2232618), CD14 (rs77083413, rs4914), TLR-4 (rs5030719), IL-6 (rs13306435) and TNF-α (rs35131721) were genotyped in 479 cases of sporadic colorectal carcinoma and 486 healthy controls of Han Chinese in a case-control study. Single-nucleotide polymorphisms (SNPs) between cases and controls were analyzed by unconditional logistic regression. RESULTS: GA and GG genotypes of LBP rs2232596 were associated with a significantly increased risk ofCRC [odds ratio (OR) = 1.51, 95% confidence interval (CI) 1.15-1.99, P = 0.003; OR = 2.49, 95% CI 1.16-5.38, P = 0.016, respectively]. A similar association was also observed for the CG genotype of CD14 rs4914 (OR= 1.69, 95% CI 1.20-2.36, P = 0.002). In addition, a combination of polymorphisms in LBP rs2232596 and CD14 rs4914 led to a 3.4-fold increased risk of CRC (OR = 3.44, 95% CI 1.94-6.10, P = 0.000). CONCLUSION: This study highlights the LBP rs2232596 and CD14 rs4914 polymorphisms as biomarkers for elevated CRC susceptibility in the Chinese Han population.
文摘the more attention is paid to rights of minorities, the more grounds will be there for peaceful coexistence. This paper will first discuss theoretical and ideological bases of status and citizenship rights of minorities before focusing on "citizenship status of minorities" and "citizenship rights of minorities" from the viewpoint of Islam. Islam here means the collection of Quran, Prophet Muhammad's (S) Sunnah, and Imam Ali's (AS) conduct. The main question of this paper is "what status and rights have been considered by Islam for minorities to allow peaceful coexistence in a Muslim society?" "Minority" here includes both religious and non-religious minorities. "Rights" here means that part of "assets," "means," "political and social leverages," "privileges," and "conditions" which the majority is bound to by law, religious and common sense to provide for minorities. The word "status" here means to respect, serve, and provide suitable conditions which are provided just out of respect for human values not due to legal compulsion. In this paper, we will first discuss theoretical and ideological fundaments of minorities' rights before discussing "citizenship status of minorities" and "citizenship rights of minorities" from the viewpoint of Islam. By Islam, we mean Quran as well as Sunnah of Prophet Muhammad (S) and conduct of Imam All (AS).
文摘In the process of folk custom development, ecological transformation is a normal phenomenon.This article will study the minority folk dance ecology transformation based on the perspective of social historical development.The author will discuss the native pattern and variable pattern for the development of the minority folk dance and analyze the positive influence and negative influence on minority dance at this stage. To address the problems in the development, the author puts forward some countermeasures and feasible suggestions for its future development
文摘The Tu nationality (also called "Tu people" or "Tus" in the paper), one of the multiple ethnic minorities in the Hehuang Region (河湟地区) between Gansu (甘肃) and Qinghai (青海) Provinces in the northwest China, has no written language of their own, but has already created the abundant and varied colorful literary genres. Since the 1980s, folktales, as the main literary product popular in the region, have received literary criticisms and reviews from scholars and researchers in China, based on the socialist realism dominant in China in the 20th century that emphasized more on contents, motifs and even ideological significance. So far, no breakthroughs have been made in their studies even if some young scholars have tried from the formalist viewpoints. Therefore, this paper attempts to make a morphological analysis of the Tus' folktales by adopting Propp's theories, trying to find out the morphological narrative model beneath the language level of the folktales. Through the studies, we can see that collective awareness bonded by kinship is more emphasized in Tus' culture, and almost all tales end with good defeating evil. Therefore, the studies of these folktales will help us deep understand Tus' psychological conditions and positive cultural life.
文摘To help the poor and to develop tourism are two mportant problems in poverty-stricken areas. However, they were isolated for years.The PPET strategy was put forward in this paper based on PPT.The feasibility and the realistic meaning of the strategy in developing the ecotourism, overcoming poverty, and achieving prosperity of minority areas inwestern China are analyzed bytaking Xinlong county of Ganzi Tibetan Autonomous Prefecture in Sichuan Province as an example.
基金supported by the Third StageInnovation Project of CAS, National Natural Science Foundation of China (Grant No. 40671062)President Fund Project of Western Development Institute of Sichuan UniversitySouthwest University of Sci-ence and Technology projects (Grant No. 043106).
文摘The ethnic areas of western Sichuan Province are characterized by complicated topography, seismic active zone, serious soil erosion, fragile eco-environment, low level of economy, and so on. Periphery regions and central regions appear in western Sichuan Province. The socioconomic development in the central regions is at high level, whereas the ethnic areas are generally at lower level. Moreover. the deterioration of the eco-environment has seriously restricted the development of traditional industries in the ethnic areas, and it is necessary to develop environment-friendly and resource-saving industries. The ethnic areas of western Sichuan Province are rich in tourism resources, and have the potentiality of developing ecotourism. Advantages' of tourism resources in the ethnic areas should be made full use of and "comprehensive tourism " is the requirement of the characteristics and the status quo of the ethnic areas. The "comprehensive tourism development model " has the functions of ecotourism on the key industry. Based on the demands and the interaction among different industries, the model cart accelerate the development of related-industries, such as eco-agrieulture, eco-industry, eco-tertiary industry, and so on. Through implementing the comprehensive tourism model, we can fully utilize the advantages of ethnic areas, and promote the rapid and sustainable growth of regional economy, and also the harmonious development of economy, environment and society.