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氯吡格雷治疗介入术前非ST段抬高急性冠状动脉综合征30例 被引量:2
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作者 李秀琪 吴兴安 谢刚 《医药导报》 CAS 2010年第7期878-880,共3页
目的观察非ST段抬高型急性冠状动脉(冠脉)综合征患者行介入治疗前高剂量氯吡格雷(600 mg.d-1)治疗的有效性及安全性。方法选取90例拟行冠脉介入术的非ST段抬高急性冠脉综合征患者,随机分为早期常规剂量组、早期高剂量组和对照组,每组各3... 目的观察非ST段抬高型急性冠状动脉(冠脉)综合征患者行介入治疗前高剂量氯吡格雷(600 mg.d-1)治疗的有效性及安全性。方法选取90例拟行冠脉介入术的非ST段抬高急性冠脉综合征患者,随机分为早期常规剂量组、早期高剂量组和对照组,每组各30例。早期用药的两组患者于入院临床诊断明确后立即开始服用氯吡格雷,早期常规剂量组首次给予负荷量300 mg后,维持剂量75 mg.d-1;早期高剂量组首次给负荷量600 mg后,维持剂量75 mg.d-1。对照组患者于冠脉造影后决定行介入治疗前2 h内开始用药,首次服用氯吡格雷300 mg后,维持剂量75 mg.d-1。比较3组患者在冠脉介入术后3个月内心血管事件及药物不良反应的发生率。结果冠脉介入术后3个月内,早期用药组心血管事件的发生率低于对照组(P<0.01),而出血事件的发生率差异无显著性(P>0.05)。早期高剂量组患者心血管事件的发生率低于常规剂量组(P<0.01),且两组间药物不良反应的发生率差异无显著性(P>0.05)。结论冠脉介入术前早期使用高剂量氯吡格雷能够明显减少非ST段抬高急性冠脉综合征患者术后近期心血管事件的发生率,且不增加药物不良反应的发生率。 展开更多
关键词 氯吡格雷 介入术 动脉 冠状 综合征 冠脉 急性/非st段抬高
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Coronary arteriography under acupuncture anesthesia:a case report 被引量:1
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作者 李璟 樊民 +4 位作者 周嘉 朱岩峰 顾侃 李琪 洪珏 《Journal of Acupuncture and Tuina Science》 CSCD 2018年第5期319-322,共4页
Acupuncture anesthesia is a technique by partially or completely replacing anesthetics with acupuncture in surgery based on the traditional acupuncture analgesia mechanism.It emerged in the 1950s,went viral in the 197... Acupuncture anesthesia is a technique by partially or completely replacing anesthetics with acupuncture in surgery based on the traditional acupuncture analgesia mechanism.It emerged in the 1950s,went viral in the 1970s and then gradually fell into decline.In the recent years,this technique has regained attention and further research.Acupuncture anesthesia can be classified as either pure acupuncture anesthesia or acupuncture-medication combined anesthesia.To expand the application of this technique,a patient with non-ST elevation acute coronary syndrome in urgent need of percutaneous coronary intervention (PCI) received pure acupuncture anesthesia because of an allergy to lidocaine,and the operation went successfully.This is the first time that pure acupuncture anesthesia and coronary arteriography were combined,which is of great significance in further study and development of acupuncture anesthesia. 展开更多
关键词 Acupuncture Therapy Acupuncture Analgesia Acute Coronary Syndrome Non-st Elevated Myocardial Infarction Percutaneous Coronary Intervention Point Neiguan (PC 6) Point Lieque (LU 7)
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