回归型发热性非化脓性结节性脂膜炎1例

患儿男,9个月,因全身反复出现紫色硬斑伴不规则发热3月,于1990年12月1日入院。体检:体温37.8℃,营养发育欠佳,皮肤无黄染。颈部及腹股沟可触及数个浅表淋巴结,大小不等,无触庸。全身可见大小不等的紫色斑,直径约0.5cm—2cm,质地较硬,有触痛,其左手背及右足底部各有一个紫斑,找之有波动感。心肺(一),腹软,肝肋下2cm质软,无的痛,脾未触及。神经系统检查未见异常。

结节性脂膜炎3例

结节性脂膜炎，是一种罕见的疾病，我院自1997年至2004年共收治结节性脂膜炎3例，现报告如下。

Correlation Analysis of SPAD Value with Chlorophyll Content and Economic Yield Traits of Brassica napus L.

[Objective] The aim was to compare differences of SPAD value, chloro- phyll content, agronomic characters, economic characters and yield traits to analyze correlation of SPAD value with other indices and establish regression functions. [Method] Based on 34 Brassica napus L. varieties, SPAD value, chlorophyll content, agronomic characters, economic characters and yield traits were measured and re- gression functions were established according to correlations. [Result] SPAD value, chlorophyll content, agronomic and economic characters and yield traits all achieved significant level in differences among 34 varieties. Specifically, SPAD value was of extremely significant correlation with chlorophyll a and b, total chlorophyll and carotenoid, and the correlation from high to low was chl-b〉chl-z〉chl-a〉chl-x. SPAD value was of significantly positive correlation with total pod number per plant, plant height, seed number per pod, yield per plant and harvest yield, and of insignificant correlation with branch point height, effective branch number, pod density of main stem, and pod length. [Conclusion] It is simple and rapid to predict chlorophyll con- tent, economic characters and yields of Brassica napus L. with SPAD value and re- gression functions.

New Math Model for Designing Engine Radiator

Aim To raise the H-NE math model for designing engine radiators.Methods Thismodel was founded on multi-nonlinear regression technology,and the quadratic equatingmethod was used to smooth original data.Through the sensitivity analysis about radiatoroptimization designing,some major restraints were obtained.Results Type 1301C radiator wasoptimizingly renwed by use o this model,and the new radiator is more excellent than theold one in respect of the heat transfer factor and the manufacturing cost.Conclusion Theradiation performance can be improved,the area can be reduced,and the fitting scope can bewidened if this model is used in designing radiators.

湘潭电网气象灾害情况下的电力负荷预测

当今大数据技术越发完备,利用以往的大数据,对日常生活需求还是工厂等负荷的需要有一个精准的预测,在未来必将是一个重要发展方向。每天、每周每年12个月的样本数据表明,客观性的数据方法对中国电网预测精度可以满足基本的业务调度。

Plasma homocysteine levels are independently associated with alterations of large artery stiffness in men but not in women

Objectives To investigate the associations of the plasma homocysteine levels with the alterations in arterial stiffness in a commu- nity-based cohort. The gender differences in these associations were examined. Methods We evaluated the relationship between plasma homocysteine levels to three measures of vascular ftmction [carotid-femoral pulse wave velocity （CF-PWV）, carotid-ankle PWV （CA-PWV） and heart rate corrected augmentation index （AI）] in 1680 participants （mean age： 61.5 years; 709 men, 971 women） from communities of Beijing, China. Results In univariate analysis, plasma homocysteine levels was positively related to the CF-PWV （r = 0.211, P 〈 0.0001） and CA-PWV （r = 0.148, P 〈 0.0001）, whereas inversely associated with AI （r = -0.052, P = 0.016）. In multiple linear regression models adjusting for covariants, plasma homocysteine remained positively related to the CF-PWV （standardized 13 = 0.065, P = 0.007） in total cases. When the groups of men and women were examined separately, plasma homocysteine remained positively associated with the CF-PWV （standardized β = 0.082, P = 0.023） in men, whereas the relations between homocysteine and any of the arterial stiffness indices were not further present in women. Conclusions In Chinese population, plasma homocysteine levels are independently associated with alterations of large artery stiffness in men but not in women.

Association of chronic viral hepatitis B with insulin resistance

AIM:To investigate the relationship between chronic viral hepatitis B(CVHB) and insulin resistance(IR) in Korean adults.METHODS:A total of 7880 adults(3851 men,4029 women) who underwent a comprehensive medical examination were enrolled in this study.Subjects diagnosed with either diabetes mellitus,or any other disorder that could influence their insulin sensitivity,were rejected.Anthropometry,metabolic risk factors,hepatitis B surface antigen,hepatitis B surface antibody,hepatitis B core antibody,fasting plasma glucose and insulin were measured for all subjects.Homeostasis model assessment(HOMA),quantitative insulin check index(QUICKI),and Mf fm index were used for determining insulin sensitivity.Each participant was categorized into a negative,recovery,or CVHB group.To compare variables between groups,a t-test and/or one-way analysis of variance were used.Partial correlation coefficients were computed to present the association between insulin resistance and other variables.Multiple logistic regression analysis was used to assess the independent association between CVHB and IR.RESULTS:The mean age of men and women were 48.9 and 48.6 years,respectively.Subjects in the CVHB group had significantly higher waist circumference [(86.0 ± 7.7 cm vs 87.3 ± 7.8 cm,P = 0.004 in men),(78.3 ± 8.6 cm vs 80.5 ± 8.5 cm,P < 0.001 in women)],cystatin C [(0.96 ± 0.15 mg/dL vs 1.02 ± 0.22 mg/dL,P < 0.001 in men),(0.84 ± 0.15 mg/dL vs 0.90 ± 0.16 mg/dL,P < 0.001 in women)],fasting insulin [(5.47 ± 3.38 U/mL vs 6.12 ± 4.62 U/mL,P < 0.001 in men),(4.57 ± 2.82 U/mL vs 5.06 ± 3.10 U/mL,P < 0.001 in women)] and HOMA index [(1.24 ± 0.86 vs 1.43 ± 1.24,P < 0.001 in men),(1.02 ± 0.76 vs 1.13 ± 0.87,P = 0.033 in women)] compared to control group.The HOMA index revealed a positive correlation with body mass index(BMI)(r = 0.378,P < 0.001),waist circumference(r =0.356,P < 0.001),percent body fat(r = 0.296,P < 0.001),systolic blood pressure(r = 0.202,P < 0.001),total cholesterol(r = 0.134,P < 0.001),triglycerides(r = 0.292,P < 0.001),cystatin C(r = 0.069,P < 0.001) and uric acid(r = 0.142,P < 0.001).The QUICKI index revealed a negative correlation with BMI(r =-0.254,P < 0.001),waist circumference(r = 0-0.243,P < 0.001),percent body fat(r =-0.217,P < 0.001),systolic blood pressure(r =-0.132,P < 0.001),total cholesterol(r =-0.106,P < 0.001),triglycerides(r =-0.205,P < 0.001),cystatin C(r =-0.044,P < 0.001) and uric acid(r =-0.096,P < 0.001).For subjects identified with IR,the odds ratio of an accompanying diagnosis of chronic hepatitis B was 1.534(95% CI:1.158-2.031,HOMA index criteria) or 1.566(95% CI:1.124-2.182,QUICKI criteria) after adjustment for age,gender,BMI,and amount of alcohol consumption.CONCLUSION:Our study demonstrates that CVHB is associated with IR.CVHB may need to be monitored for occurrence of IR and diabetes mellitus.

Method of forecasting seismic energy induced by longwall exploitation based on changes in ground subsidence

A method of forecasting total seismic energy induced by longwall exploitation, based on changes in ground subsidence, is presented in the form of a linear regression model with one with one independent variable. In the method, ground subsidence is described with a cross-section area of a subsidence trough Pw along a line of observations in the direction of an advancing longwall front, approximately along the axis of the longwall area. Total seismic energy is determined on the basis of seismic energy data of tremors induced by exploitation. The presentation consists of a detailed method and evaluation of its predictive ability for the area of longwall exploitation within the region of one of the coal mines in the Upper Silesian Coal Basin. This method can be used for forecasting the total seismic energy released by tremors within the area directly connected with the exploitation, in which the seismic activity induced by this exploitation occurs. The estimation of the parameters of the determined model should each time be carried out with investigations of the correctness of the model. The method cannot be applied when the number of recorded phenomena is small and when there is insufficient data to make it possible to calculate the index Pw.

Pyrolysis Characteristics and Kinetics of Methyl Oleate Based on TG-FTIR Method

The thermal decomposition characteristics of methyl oleate were preliminarily investigated under nitrogen atmo-sphere by a thermogravimetric analyzer when the ester was heated at a heating rate of 10℃/min from room temperature to 600℃. Furthermore, the pyrolytic and kinetic characteristics of methyl oleate were intensively studied at different heating rates. The gaseous species obtained during thermal decomposition were also identiifed by the TG-FTIR coupling analysis. The results showed that the pyrolysis of methyl oleate proceeded in three stages, viz. the drying stage, the main pyrolysis stage and the residual pyrolysis stage. The initial decomposition temperature, the maximum weight loss temperature, the peak decomposition temperature and the rate of maximum weight loss of methyl oleate increased with the increasing heating rates. Gaseous CO, CO2 and H2O were the typical decomposition products from pyrolysis of methyl oleate. In addition, a kinetic model for thermal decomposition of methyl oleate was built up based on the experimental results using the Coats-Redfern integral method and the multiplelinear regression method. The activation energy, the preexponential factor, the reaction order and the kinetic equation for thermal decomposition of methyl oleate were obtained. Comparison of the experimental data with the calculated ones and analysis of statistical errors of pyrolysis ratios demonstrated that the kinetic model was reliable for studying the pyrolysis of methyl oleate. Finally, the kinetic compensation effect between the preexponential factors and the activation energy in the pyrolysis of methyl oleate was also conifrmed.

Correlation and path analysis of morphological and weight traits in marine gastropod Glossaulax reiniana

Using correlation and path analysis, the genetic correlation between weight traits and morphological traits was determined in the marine gastropod Glossaulax reiniana. A total of 100 G. reiniana individuals from a wild population were used. Shell width （X1）, shell height （X2）, umbo-callus height （X3）, body width （X4）, operculum length （X5）, operculum width （X6）, body weight （Y1） and soft-tissue weight （Y2） were measured, and the correlation coefficient matrix calculated. Morphological traits were used as independent variables and weight traits as dependent variables for path coefficient analysis. Path coefficients, correlation indices and determination coefficients were also determined. Results indicate that the correlation coefficients associated with each morphological and weight trait were all highly significant （P〈0.01）. After deleting redundant independent variables, the following optimum multiple regression equations were obtained using stepwise multiple regression analysis： Y1=-29.317＋0.362X2＋0.349X4＋ 1.190）（5 for body weight; and Y2=-17.292＋0.166X1＋0.171X2＋0.703X5, for soft-tissue weight. Operculum height had the highest positive direct correlation with both body weight and soft-tissue weight, which was in accordance with the test results obtained from determinate coefficient analysis. The indication of high genetic correlations between weight traits and morphological traits will provide valuable information for G. reiniana breeding programs.

Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis

AIM： To investigate whether the patatin-/ike phosph- olipase domain containing-3 gene （PNPLA3） I148M polymorphism is associated with steatosis, fibrosis stage, and cirrhosis in hereditary hemochromatosis （HH）. METHODS： We studied 174 consecutive unrelated homozygous for the C282Y HFE mutation of HH （C282Y＋/＋ HH） patients from Northern Italy, for whom the presence of cirrhosis could be determined based on histological or clinical criteria, without excessive alcohol intake （〈 30/20 g/d in males or females） or hepatitis B virus and hepatitis C virus viral hepatitis. Steatosis was evaluated in 123 patients by histology （n = 100） or ul- trasound （n = 23）. The PNPLA3 rs738409 single nucle- otide polymorphism, encoding for the p.148M protein variant, was genotyped by a Taqman assay （assay on demand, Applied Biosystems）. The association of the PNPLA3 I148M protein variant （p.I148M） with steatosis, fibrosis stage, and cirrhosis was evaluated by logistic regression analysis. RESULTS： PNPLA3 genotype was not associated with metabolic parameters, including body mass index （BMI）, the presence of diabetes, and lipid levels, but the pres- ence of the p.148M variant at risk was independently associated with steatosis [odds ratio （OR） 1.84 per p.148M allele, 95% confidence interval （CI）： 1.05-3.31; P = 0.037], independently of BMI and alanine amino- transaminase （ALT） levels. The p.148M variant was also associated with higher aspartate aminotransferase （P = 0.0014） and ALT levels （P = 0.017） at diagnosis, independently of BMI and the severity of iron overload. In patients with liver biopsy, the 148M variant was independently associated with the severity （stage） of fibrosis （estimated coefficient 0.56 ± 0.27, P = 0.041）. In the overall series of patients, the p.148M variant was associated with cirrhosis in lean （P = 0.049）, but not in overweight patients （P = not significant）. At logistic regression analysis, cirrhosis was associated with BMI 〉~ 25 （OR 1.82, 95% CI： 1.02-3.55）, ferritin 〉 1000 ng/mL at diagnosis （OR 19.3, 95% CI： 5.3-125）, and with the G allele in patients with BMI 〈 25 （OR 3.26, 95% CI： 1.3-10.3）. CONCLUSION： The PNPLA3 I148M polymorphism may represent a permissive factor for fibrosis progression in patients with C282Y＋/＋ HH.

Prediction of Soil Depth from Digital Terrain Data by Integrating Statistical and Visual Approaches

Information about the spatial distribution of soil attributes is indispensable for many land resource management applications; however, the ability of soil maps to supply such information for modern modeling tools is questionable. The objectives of this study were to investigate the possibility of predicting soil depth using some terrain attributes derived from digital elevation models （DEMs） with geographic information systems （GIS） and to suggest an approach to predict other soil attributes. Soil depth was determined at 652 field observations over the A1-Muwaqqar Watershed （70 km2） in Jordan. Terrain attributes derived from 30-m resolution DEMs were utilized to predict soil depth. The results indicated that the use of multiple linear regression models within small watershed subdivisions enabled the prediction of soil depth with a difference of 50 cm for 77% of the field observations. The spatial distribution of the predicted soil depth was visually coincided and had good correlations with the spatial distribution of the classes amalgamating three terrain attributes, slope steepness, slope shape, and compound topographic index. These suggested that the modeling of soil-landscape relationships within small watershed subdivisions using the three terrain attributes was a promising approach to predict other soil attributes.

Estimation of surface tension of organic compounds using quantitative structure-property relationship

A novel quantitative structure-property relationship （QSPR） model for estimating the solution surface tension of 92 organic compounds at 20℃ was developed based on newly introduced atom-type topological indices. The data set contained non-polar and polar liquids, and saturated and unsaturated compounds. The regression analysis shows that excellent result is obtained with multiple linear regression. The predictive power of the proposed model was discussed using the leave-one-out （LOO） cross-validated （CV） method. The correlation coefficient （R） and the leave-one-out cross-validation correlation coefficient （Rcv） of multiple linear regression model are 0.991 4 and 0.991 3, respectively. The new model gives the average absolute relative deviation of 1.81% for 92 substances. The result demonstrates that novel topological indices based on the equilibrium electro-negativity of atom and the relative bond length are useful model parameters for QSPR analysis of compounds.

Influence of brittleness and confining stress on rock cuttability based on rock indentation tests

In order to understand the influence of brittleness and confining stress on rock cuttability,the indentation tests were carried out by a conical pick on the four types of rocks.Then,the experimental results were utilized to take regression analysis.The eight sets of normalized regression models were established for reflecting the relationships of peak indentation force(PIF)and specific energy(SE)with brittleness index and uniaxial confining stress.The regression analyses present that these regression models have good prediction performance.The regressive results indicate that brittleness indices and uniaxial confining stress conditions have non-linear effects on the rock cuttability that is determined by PIF and SE.Finally,the multilayer perceptual neural network was used to measure the importance weights of brittleness index and uniaxial confining stress upon the influence for rock cuttability.The results indicate that the uniaxial confining stress is more significant than brittleness index for influencing the rock cuttability.

Mapping methods for output-based objective speech quality assessment using data mining

Objective speech quality is difficult to be measured without the input reference speech.Mapping methods using data mining are investigated and designed to improve the output-based speech quality assessment algorithm.The degraded speech is firstly separated into three classes(unvoiced,voiced and silence),and then the consistency measurement between the degraded speech signal and the pre-trained reference model for each class is calculated and mapped to an objective speech quality score using data mining.Fuzzy Gaussian mixture model(GMM)is used to generate the artificial reference model trained on perceptual linear predictive(PLP)features.The mean opinion score(MOS)mapping methods including multivariate non-linear regression(MNLR),fuzzy neural network(FNN)and support vector regression(SVR)are designed and compared with the standard ITU-T P.563 method.Experimental results show that the assessment methods with data mining perform better than ITU-T P.563.Moreover,FNN and SVR are more efficient than MNLR,and FNN performs best with 14.50% increase in the correlation coefficient and 32.76% decrease in the root-mean-square MOS error.

Prediction of net energy value of corn and soybean meal for broiler chicken

Net energy （NE） is the most accurate and unbiased way in characterizing the energy content of feed. Comparatively speaking, research on NE prediction is still limited and under development. Therefore, it is important to correctly assess NE for further study. In this study, an energy balance trial and a fasting metabolism trial were used to measure the net energy for production （NEp） and the net energy for maintenance （NEm）, respectively. Meanwhile, a backward method of multiple linear regression was applied to establish prediction equations for NE. The results showed that corn NE is about 2 times higher than that of soybean meal, due to the efficiency of ME （k） utilization by the ingredients. Meanwhile, AME and acid detergent fiber （ADF） were found to be better predictors for the NE of corn and soybean meal, respectively. Furthermore, Equations 1（R^2=0.993, RSD=0.0091） and 12 （R^2=0.999, RSD=0.0008） were found to be better prediction equations in multiple linear regression analyses for corn and soybean meal, respectively. However, considering the cost of the analytical procedures, the accuracy of the prediction （RSD）, and the additional variability or errors due to interlaboratory variance, Equation 4 （R^2=0.990, RSD=0.0109） and Equation 20 （R^2=0.996, RSD=0.0043） were better models for corn and soybean meal, respectively. Nevertheless, these equations for corn and soybean meal should be applied only under similar experimental conditions.

Is hepatic neoplasm-related pyogenic liver abscess a distinct clinical entity?

AIM: To compare the clinical characteristics of pyogenic liver abscess (PLA) in patients with and without hepatic neoplasm (HN). METHODS: We performed a retrospective analysis involving patients with PLA. The demographic, clinical features, laboratory and imaging findings, management and outcome of patients with and without HN were studied. RESULTS: From January 2000 to December 2009 inclusive, 318 patients (35 with HN) had PLA, and mean age and comorbidity were comparable between the two groups. More patients with HN experienced right upper quadrant pain (68.6% vs 52.7%, P < 0.04), developed jaundice (14.3% vs 5.7%, P < 0.03) and hepatomegaly (17.1% vs 3.9%, P < 0.01), and had higher serum total bilirubin level (43.3 μmol/L vs 30.0 μmol/L, P = 0.05). Most patients in both groups had PLAs in the right hepatic lobe, and biliary tract disorder was the most common underlying cause (71.4% and 61.8%). However, more PLAs in the HN group were associated with thicker abscess wall (37.1% vs 19.4%, P < 0.01), septal lobulation (77.1% vs 58%, P < 0.02), gaseous cavitation (17% vs 7.8%, P = 0.03), portal thrombophlebitis (11.4% vs 1.8%, P < 0.01) and aerobilia (25.9% vs 5.5%, P < 0.01). Mixed bacterial growth (40% vs 15.2%, P < 0.01) and Gram-negative bacilli (22.8% vs 60.4%, P < 0.01) were dominant isolates in PLAs with and without HN, respectively. Although incidence of the complications was comparable between the two groups, patients with HN had a higher mortality rate than those without (71.4% vs 8.8%, P < 0.01). Multivariate logistic regression analysis revealed underlying active malignancy [odds ratio (OR): 40.45, 95% CI: 14.76-111.65], hypoalbuminemia (OR: 1.22, 95% CI: 1.14-1.38), disseminated intravascular coagulation (OR: 3.32, 95% CI: 1.19-9.69) and acute coronary syndrome (OR: 4.48, 95% CI: 1.08-17.8) were independent risk factors associated with mortality. However, several HN cases, presented concurrently with PLAs, were found to have curative resectable tumors and had good prognosis after surgery. CONCLUSION: PLA associated with HN tends to form a distinct clinical syndrome with a different extent of clinical manifestations, radiological and microbiological features and complications.

Resistin might not be a risk factor for carotid artery atherosclerosis in elderly Chinese males

Objective To investigate the correlation between the serum resistin level and carotid artery atherosclerosis in elderly Chinese males. Methods The study enrolled 235 elderly Chinese males [median age 76 （range 60-97） years] scheduled for ultrasound examination of carotid artery plaque and determination of carotid artery intima-media thickness （CIMT）. They were divided into carotid atherosclerotic plaque （CAP） and carotid atherosclerotic plaque-free （CAP-free） groups according to the ultrasound results. Their clinical profiles were col-lected, and the serum resistin and other blood biochemistry levels were determined.Results The CAP group was older and had a thicker mean CIMT than the CAP-free group. However, there was no difference in the serum resistin level between the groups. CIMT was positively correlated with age （r = 0.299,P〈 0.001）. The serum resistin level was not correlated with CIMT, even after controlling for age. Multiple linear regression analysis revealed that age （β = 0.001,P〈 0.001） and body mass index （β = 0.002,P= 0.015） were significantly and posi-tively correlated with the mean CIMT. Only age [odds ratio （OR）： 1.159; 95% confidence interval （CI）： 1.078-1.183,P〈 0.001] was associ-ated with the presence of carotid artery atherosclerotic plaque. The serum resistin level was not correlated with the mean CIMT or associated with the presence of carotid artery atherosclerotic plaque.Conclusion The results suggest that resistin might not be a risk factor for atherosclerosis in elderly Chinese males.

Comparison of very-high-frequency ultrasound assessment of radial arterial wall layers after first and repeated transradial coronary procedures

Background Transradial coronary procedure （TRP） traumatizes the radial artery （RA）, especially resulting in changes to arterial wall morphology. This study explored the significance of the early onset of traumatic effects to wall layers of the RA following the first TRP （FTRP） and repeat TRP （RTRP） using very-high-frequency ultrabiomicroscopy （VHFUBM）. Methods A total of 1431 patients that re- ceived TRP were divided into the FTRP group that comprised 781 patients and the RTRP group that comprised 650 patients depending on the number of procedures. Two-dimensional RA images were acquired by 30-55 MHz ultrasound one day before and one day after the pro- cedure. Results After TRP, the incidence of intimal tears, medial dissections and external elastic lamina fracture were greater in the RTRP （P 〈 0.001）. The RTRP group showed significantly thicker intimal thickness （IT）, media thickness （MT）, adventitia thickness and all complex layer thicknesses as compared with the FTRP group （P 〈 0.001）. Conclusions Multivariate linear regression analysis discovered that repeated TRP and other observations were independent predictors of increased IT in post-operative RA. VHFUBM provides an approach to study structural and histopathological injury in the wall layers of RA which showed increased trauma to the RA following RTRP.

Relationship of level of sex hormone and sex hormone receptor with development of metabolic syndrome in elderly men

Objective The sex hormone and the corresponding receptor may play some roles in the development of the metabolic syndrome （MS） in the elderly men. This study was designed to examine the relationship of level of the sex hormone and androgen receptor with MS in elderly men, thus to investigate the possible pathogenesis of MS. Methods This cross sectional study enrolled 587 elderly men, including 400 healthy controlls aged 62-92 years and 187 MS patients aged 60-87 years in Wan Shou Lu area of Beijing city. Dehydroepiandrosterone sulfate （DHAE-S）, total testosterone （TT）, sex hormone binding globulin （SHBG）, free testosterone （FT）, follicle-stimulating hormone （FSH）,Estradiol （E2）,luteinizing hormone（LH） and androgen receptor （AR） in blood were tested. Statistical analyses included the comparison analysis of variables and independent variables, correlation analysis using multi-factor linear regression, and multiple logistic regression analysis. Results DHAE-S, TT, SHBG, FT and AR fluorescence intensity in healthy control group were higher than those in MS group, however, FSH and E2 levels were lower in healthy group. Age was negatively correlated with diastolic blood pressure （DBP） and FT, but positively correlated with systolic blood pressure （SBP） and E2. AR fluorescence intensity was negatively correlated with SBP and LH. The logistic regression equation showed the negative correlation between DHEA-S, SHBG and the development of MS. Conclusions There are low levels of DHEA-S, TT, SHBG, FT and AR in the elderly patients with MS. On the contrary, FSH and E2 concentration are higher. It can be suggested that low levels of DHEA-S and SHBG may be the potential risk factors of MS in elderly men.