Background： Minangkabau Malays （Melayu Minangkabau） is one of the Malay sub ethnic groups in Peninsular Malaysia. During the late 17th and early 18th centuries, migration of the Minangs from West Sumatra to the sta...Background： Minangkabau Malays （Melayu Minangkabau） is one of the Malay sub ethnic groups in Peninsular Malaysia. During the late 17th and early 18th centuries, migration of the Minangs from West Sumatra to the state of Negeri Sembilan Darul Khusus in Peninsular Malaysia took place and their descendants now form the main sub ethnic group in this state. The genetic polymorphisms of Y chromosome at DYS 287 locus were analyzed in Minangkahau Malays. Methods： A total of 41 buccal cells from healthy unrelated individual＇s males from Minangkabau Malays were typed for the DYS 287. The PCR products were separated on 2% （w/v） agarose gel followed by visualization under UV light. Results： Three out of 41 samples （7.32%） showed insertion （YAP＋） polymorphism, while the rest of the samples （92.68%） showed deletion （YAP-） polymorphism. This is the first report concerning the YAP in Malay population at Peninsular Malysia. Conclusion： The vAluable data obtained in this study will contribute to fill in the gap in the knowledge of YAP distribution in Malaysian population and will allow continuous interpretation of the evolution of YAP.展开更多
The association of the porcine Pitx2c gene with meat quality traits was investigated in the present study. A total of eight single nucleotide polymorphisms （SNPs） were found. Allele frequencies of four SNPs were fur...The association of the porcine Pitx2c gene with meat quality traits was investigated in the present study. A total of eight single nucleotide polymorphisms （SNPs） were found. Allele frequencies of four SNPs were further detected in four commercial breeds and eight Chinese indigenous breeds. Single SNP and meat quality associations were analyzed in a YorkshirexMeishan F2 population. The SNPs c.474C〉T （P〈0.01） and c.636C〉T （P〈0.05） showed a significant association with meat color （MCV1）. The SNPs c,＊37G〉A and c.＊47G〉A were significantly associated with drip loss rate （DLR）, water holding capacity （WHC） and meat color value （MCV1） consistently （P〈0.05）. Linkage disequilibrium （LD） analysis revealed that the adjacent SNPs were in LD. Two major haplotypes were identified, and association analysis between haplotype combinations and meat quality indicated that the presence of two copies of haplotype 1 -CCGG- may improve meat quality.展开更多
文摘Background： Minangkabau Malays （Melayu Minangkabau） is one of the Malay sub ethnic groups in Peninsular Malaysia. During the late 17th and early 18th centuries, migration of the Minangs from West Sumatra to the state of Negeri Sembilan Darul Khusus in Peninsular Malaysia took place and their descendants now form the main sub ethnic group in this state. The genetic polymorphisms of Y chromosome at DYS 287 locus were analyzed in Minangkahau Malays. Methods： A total of 41 buccal cells from healthy unrelated individual＇s males from Minangkabau Malays were typed for the DYS 287. The PCR products were separated on 2% （w/v） agarose gel followed by visualization under UV light. Results： Three out of 41 samples （7.32%） showed insertion （YAP＋） polymorphism, while the rest of the samples （92.68%） showed deletion （YAP-） polymorphism. This is the first report concerning the YAP in Malay population at Peninsular Malysia. Conclusion： The vAluable data obtained in this study will contribute to fill in the gap in the knowledge of YAP distribution in Malaysian population and will allow continuous interpretation of the evolution of YAP.
基金supported by the National Basic Research Program of China (Grant No.2006CB102102)National High Technology Research and Development Program (Grant No.2006AA10Z1D6)+1 种基金National Natural Science Foundation of China (Grant No.30800782)New Teacher Research Fund for the Doctoral Program of Higher Education (Grant No.20070504064)
文摘The association of the porcine Pitx2c gene with meat quality traits was investigated in the present study. A total of eight single nucleotide polymorphisms （SNPs） were found. Allele frequencies of four SNPs were further detected in four commercial breeds and eight Chinese indigenous breeds. Single SNP and meat quality associations were analyzed in a YorkshirexMeishan F2 population. The SNPs c.474C〉T （P〈0.01） and c.636C〉T （P〈0.05） showed a significant association with meat color （MCV1）. The SNPs c,＊37G〉A and c.＊47G〉A were significantly associated with drip loss rate （DLR）, water holding capacity （WHC） and meat color value （MCV1） consistently （P〈0.05）. Linkage disequilibrium （LD） analysis revealed that the adjacent SNPs were in LD. Two major haplotypes were identified, and association analysis between haplotype combinations and meat quality indicated that the presence of two copies of haplotype 1 -CCGG- may improve meat quality.
