Objective: To study the prognostic value of the pathological margin and molecular margin marked by eIF4E and P53 protein in laryngeal carcinoma. Methods: The prognostic value of pathological and molecular margin was s...Objective: To study the prognostic value of the pathological margin and molecular margin marked by eIF4E and P53 protein in laryngeal carcinoma. Methods: The prognostic value of pathological and molecular margin was studied in 253 cases and 67 cases respectively, the latter were pathological negative margin chosen from the former. Immunohistochemisty was used to detect the expression of eIF4E and p53 proteins. Results: The rate of pathological, p53 and eIF4E positive margins was 20.2%, 19.4% and 32.8% respectively. The recurrent rate of those with positive margins was higher than that of negative margins, which including pathological margin (70.6% vs 35.1%, P =0.0000), p53 margin (69.2% vs 33.3%, P =0.018) and eIF4E margin (63.6% vs 28.9%, P =0.018); The survival rate of those with negative margins was higher than those with positive margins, including pathological margin (the 5-year cumulative survival rate was 37.52% and 64.37% respectively, P =0.0023), p53 margin (the 5-year cumulative survival rate was 24.62% and 75.69% respectively, P =0.0012) and eIF4E margin (the 5-year cumulative survival rate was 43.31% and 77.52% respectively, P =0.0006). Conclusion: The prognosis of those with both pathological and molecular positive margins was worse than that of the negative margins; Both the eIF4E and p53 were useful markers to pick out the poor prognostic patients from those with pathological negative margin, and the former seemed to be more potential.展开更多
Basic foreign language teaching for language majors plays a significant role in the process of foreign language teaching and is also a crucial stage in the training of foreign language talents. During the stage teache...Basic foreign language teaching for language majors plays a significant role in the process of foreign language teaching and is also a crucial stage in the training of foreign language talents. During the stage teachers should learn about students＇ learning motives and the beginners＇ psychological state to rouse students＇ interest and mobilize their initiatives so that students can change from passive learning to active learning. The teaching effects will thereby be substantially enhanced.展开更多
The balkanization of reality by Aristotelian Philosophy has been a thought provoking exercise in the history of Western Philosophy. Aristotle＇s idea as conceptualized by Asouzu as Philosophy of Essence has been the c...The balkanization of reality by Aristotelian Philosophy has been a thought provoking exercise in the history of Western Philosophy. Aristotle＇s idea as conceptualized by Asouzu as Philosophy of Essence has been the central instrument for bifurcation and polarization of all entities into classes, such as： Essence and Accident, Matter and Form, Cause and Effect, Rationalism and Empiricism etc. This dualistic ontology be believes has eaten deeply into the mind of Western scholars to perceive science dualistically. In view of the above, the disagreement with Aristotle＇s compartmentalization of reality from Ibuanyidanda Philosophy （Philosophy of Complementarity） by Asouzu is an attempt to restructure scientific dualistic ontology into one unified, non-polarized, non-absolutistic, harmonious framework capable of fascinating unity in science. Hence, the subject matter of Ibuanyidanda Philosophy is to restore the broken unity between theory and praxis that exists in science because everything that exists serves a missing link of reality. The aim of this paper is to critically examine from the philosophical eye, the various critique by Asouzu on this thought provoking polarization of reality in Aristotle＇s Philosophy of Essence. We are of the view that Aristotle had to balkanize reality to solve the various problems of his era. Thus, if applied to contemporary scientific issues, it will lead us to no unity and growth in science. Furthermore, from Ibuanyidanda＇s perspective, we are of the view that its nature of harmonious non-polarized ontology is a breakthrough to contemporary scientific issues especially the debate within macro physics, theory of relativity, and sub-atomic particles physics （Quantum Mechanics）.展开更多
This paper shows prospective methodology as a tool to generate strategic knowledge for designing sustainable futures. The strategic prospective is a social science discipline dedicated to explore the future. Based on ...This paper shows prospective methodology as a tool to generate strategic knowledge for designing sustainable futures. The strategic prospective is a social science discipline dedicated to explore the future. Based on qualitative methods with participative experts and stakeholders, the strategic prospective allows designing different future scenarios and planning the transformation of a current situation into a desired future. To design sustainable futures, this paper proposes a four-stage methodology： understanding the context; strategy visualization; design of alternative scenarios and definition of desired future; and planning its construction. This methodology makes evident the possibility of seeking alternative scenarios for a sustainable future in different scopes, particularly, in two prospective applications： biodiversity conservation and water treatment. The outcomes of the application have allowed proposing strategies and policies for the management of environmental goods, such as environmental services and water reuse, with a long-time outlook based on a collective desired future.展开更多
OBJECTIVE: To assess the impact of massage versus ear acupuncture on behavior and participation in occupational therapy of dementia patients. METHODS: We performed a controlled, randomized longitudinal trial approved ...OBJECTIVE: To assess the impact of massage versus ear acupuncture on behavior and participation in occupational therapy of dementia patients. METHODS: We performed a controlled, randomized longitudinal trial approved by the Bioethics Commission of the University of Extremadura. One hundred twenty elderly subjects with dementia institutionalized in residential homes in Extremadura (Spain) received treatment based on massage and ear acupuncture over three months. Behavior alterations, sleep disturbance, and participation in rehabilitation and eating were assessed every month during the three months of intervention, and at one and two months of follow-up after the end of treatment. The assessment was performed through a structured questionnaire with closed format ques-tions done by an occupational therapist not involved in the study. RESULTS: There was a statistically significant positive effect of massage and ear acupuncture (P< 0.001) on measured variables in the third month of intervention, which were maintained at two months after completing the treatment (P<0.021), when compared to the control group. CONCLUSION: Massage therapy and ear acupuncture can improve behavior and sleep disturbances, and increase the participation in eating and rehabilitation organized in residential homes, in dementia patients.展开更多
As an influential theory of social science, governance theory has played a prominent role in development studies over the last two decades. Because this theory originates from the Western society, Chinese academics ha...As an influential theory of social science, governance theory has played a prominent role in development studies over the last two decades. Because this theory originates from the Western society, Chinese academics have disagreed about its applicability in China, which has essentially different conditions in democracy, rule of law, and civil society from the western society. It is argued in this paper that Chinese scholars should neither take its applicability for granted based on the strong solicitude for the reality of China, nor conclude that the governance theory is not applicable in China based on rigid structural analysis. Jessop＇s Strategic- Relational Approach presents an enlightenment of practical value that actors＇ choice of strategies and actions needs investigating based on an objective understanding of the structural background. Under the existing political-administrative system of fragmented authoritarianism, C^a civil society has already developed into ＂a dynamic force outside the state system,＂ entitled to certain participation in public affairs. Such novel understanding is of great significance in developing both the study and practice of governance in China.展开更多
文摘Objective: To study the prognostic value of the pathological margin and molecular margin marked by eIF4E and P53 protein in laryngeal carcinoma. Methods: The prognostic value of pathological and molecular margin was studied in 253 cases and 67 cases respectively, the latter were pathological negative margin chosen from the former. Immunohistochemisty was used to detect the expression of eIF4E and p53 proteins. Results: The rate of pathological, p53 and eIF4E positive margins was 20.2%, 19.4% and 32.8% respectively. The recurrent rate of those with positive margins was higher than that of negative margins, which including pathological margin (70.6% vs 35.1%, P =0.0000), p53 margin (69.2% vs 33.3%, P =0.018) and eIF4E margin (63.6% vs 28.9%, P =0.018); The survival rate of those with negative margins was higher than those with positive margins, including pathological margin (the 5-year cumulative survival rate was 37.52% and 64.37% respectively, P =0.0023), p53 margin (the 5-year cumulative survival rate was 24.62% and 75.69% respectively, P =0.0012) and eIF4E margin (the 5-year cumulative survival rate was 43.31% and 77.52% respectively, P =0.0006). Conclusion: The prognosis of those with both pathological and molecular positive margins was worse than that of the negative margins; Both the eIF4E and p53 were useful markers to pick out the poor prognostic patients from those with pathological negative margin, and the former seemed to be more potential.
文摘Basic foreign language teaching for language majors plays a significant role in the process of foreign language teaching and is also a crucial stage in the training of foreign language talents. During the stage teachers should learn about students＇ learning motives and the beginners＇ psychological state to rouse students＇ interest and mobilize their initiatives so that students can change from passive learning to active learning. The teaching effects will thereby be substantially enhanced.
文摘The balkanization of reality by Aristotelian Philosophy has been a thought provoking exercise in the history of Western Philosophy. Aristotle＇s idea as conceptualized by Asouzu as Philosophy of Essence has been the central instrument for bifurcation and polarization of all entities into classes, such as： Essence and Accident, Matter and Form, Cause and Effect, Rationalism and Empiricism etc. This dualistic ontology be believes has eaten deeply into the mind of Western scholars to perceive science dualistically. In view of the above, the disagreement with Aristotle＇s compartmentalization of reality from Ibuanyidanda Philosophy （Philosophy of Complementarity） by Asouzu is an attempt to restructure scientific dualistic ontology into one unified, non-polarized, non-absolutistic, harmonious framework capable of fascinating unity in science. Hence, the subject matter of Ibuanyidanda Philosophy is to restore the broken unity between theory and praxis that exists in science because everything that exists serves a missing link of reality. The aim of this paper is to critically examine from the philosophical eye, the various critique by Asouzu on this thought provoking polarization of reality in Aristotle＇s Philosophy of Essence. We are of the view that Aristotle had to balkanize reality to solve the various problems of his era. Thus, if applied to contemporary scientific issues, it will lead us to no unity and growth in science. Furthermore, from Ibuanyidanda＇s perspective, we are of the view that its nature of harmonious non-polarized ontology is a breakthrough to contemporary scientific issues especially the debate within macro physics, theory of relativity, and sub-atomic particles physics （Quantum Mechanics）.
文摘This paper shows prospective methodology as a tool to generate strategic knowledge for designing sustainable futures. The strategic prospective is a social science discipline dedicated to explore the future. Based on qualitative methods with participative experts and stakeholders, the strategic prospective allows designing different future scenarios and planning the transformation of a current situation into a desired future. To design sustainable futures, this paper proposes a four-stage methodology： understanding the context; strategy visualization; design of alternative scenarios and definition of desired future; and planning its construction. This methodology makes evident the possibility of seeking alternative scenarios for a sustainable future in different scopes, particularly, in two prospective applications： biodiversity conservation and water treatment. The outcomes of the application have allowed proposing strategies and policies for the management of environmental goods, such as environmental services and water reuse, with a long-time outlook based on a collective desired future.
文摘OBJECTIVE: To assess the impact of massage versus ear acupuncture on behavior and participation in occupational therapy of dementia patients. METHODS: We performed a controlled, randomized longitudinal trial approved by the Bioethics Commission of the University of Extremadura. One hundred twenty elderly subjects with dementia institutionalized in residential homes in Extremadura (Spain) received treatment based on massage and ear acupuncture over three months. Behavior alterations, sleep disturbance, and participation in rehabilitation and eating were assessed every month during the three months of intervention, and at one and two months of follow-up after the end of treatment. The assessment was performed through a structured questionnaire with closed format ques-tions done by an occupational therapist not involved in the study. RESULTS: There was a statistically significant positive effect of massage and ear acupuncture (P< 0.001) on measured variables in the third month of intervention, which were maintained at two months after completing the treatment (P<0.021), when compared to the control group. CONCLUSION: Massage therapy and ear acupuncture can improve behavior and sleep disturbances, and increase the participation in eating and rehabilitation organized in residential homes, in dementia patients.
文摘As an influential theory of social science, governance theory has played a prominent role in development studies over the last two decades. Because this theory originates from the Western society, Chinese academics have disagreed about its applicability in China, which has essentially different conditions in democracy, rule of law, and civil society from the western society. It is argued in this paper that Chinese scholars should neither take its applicability for granted based on the strong solicitude for the reality of China, nor conclude that the governance theory is not applicable in China based on rigid structural analysis. Jessop＇s Strategic- Relational Approach presents an enlightenment of practical value that actors＇ choice of strategies and actions needs investigating based on an objective understanding of the structural background. Under the existing political-administrative system of fragmented authoritarianism, C^a civil society has already developed into ＂a dynamic force outside the state system,＂ entitled to certain participation in public affairs. Such novel understanding is of great significance in developing both the study and practice of governance in China.
