Objective: To evaluate the effects of dietary factors on cancer and non-communicable diseases. Methods: A correlation analysis between the consumption of various indicator food and mortality rates of cancer or non-com...Objective: To evaluate the effects of dietary factors on cancer and non-communicable diseases. Methods: A correlation analysis between the consumption of various indicator food and mortality rates of cancer or non-communicable diseases was conducted by collecting secondary data from national nutrition surveys in Japan. Results: The consumption of cereal foods, plant energy and plant protein showed a significant negative correlation with mortality of cancer, heart diseases and diabetes; negatively related to the lung cancer and colon cancer in both sexes; a strong negative correlation with mortality of rectum cancer, liver cancer and prostate cancer in males, and of breast cancer in females; and a significant positive correlation with the stomach cancer in both sexes. The consumption of animal foods, animal energy, animal protein and fat showed a strong positive correlation with cancer, heart diseases and diabetes; a positive relations to lung cancer and colon cancer in both sexes, and rectum cancer, liver cancer and prostate cancer in males and breast cancer in females. On the contrary, a strong negative correlation was found in stomach cancer in both sexes; and esophagus cancer, liver cancer and uterus cancer in females. The consumption of vegetables and fruits showed a weak negative correlation with stomach cancer. Conclusion : The results suggest that diet not only plays a significant role in increasing the risks of some kinds of cancer or non-communicable diseases but also has a preventive effect. It is very important that dietary balance should be emphasized to prevent cancer and non-com-municable diseases.展开更多
Objectives: To compare multiplex fluorescent PCRwith serum type-specific antibody detection in thediagnosis of herpes simplex virus (HSV) infection andto evaluate its significance in the diagnosis of genitalherpes.Met...Objectives: To compare multiplex fluorescent PCRwith serum type-specific antibody detection in thediagnosis of herpes simplex virus (HSV) infection andto evaluate its significance in the diagnosis of genitalherpes.Methods: We detected HSV infection in 121 speci-mens collected from patients with genital herpesusing both multiplex fluorescent PCR and serum type-specific antibody detection. HSV viral isolation wasused as the standard control.Results: When compared with the viral isolation, thesensitivity and specificity for multiplex fluorescentPCR were 100% and 88.89%, respectively afterdiscrepant analysis. The sensitivity and specificity fortype-specific antibody detection was 77.68 % and77.78 %, respectively. However, the type-specificantibody detected HSV in two asymptomatic patientswhile the multiplex fluorescent PCR couldn’t detectany HSV DNA from those specimens.Conclusions: Multiplex fluorescent PCR is a verysensitive and specific method for detection and typingof HSV in the lesion of genital herpes, it failed todetect HSV DNA from the asymptomatic patients.Serum type-specific antibody detection was a lesssensitive and specific test but could detect the specificantibody from some asymptomatic patients. Thecombination of these two techniques would allow rapid,sensitive and accurate detection and typing of HSVand help clinical diagnosis and epidemiologic survey-ing of genital herpes.展开更多
AIM:IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs).Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up s...AIM:IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs).Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study. METHODS:Eight hundred and seventy-three IBD patients were enrolled (ulcerative colitis/UC/:619,m/f:317/302, mean age at presentation:38.3 years,average disease duration:11.2 years;Crohn's disease/CD/:254,m/f:125/129, mean age at presentation:32.5 years,average disease duration:9.2 years).Intestinal,extraintestinal signs and laboratory tests were monitored regularly.Any alteration suggesting an EIMs was investigated by a specialist. RESULTS:A total of 21.3% of patients with IBD had EIM (UC:15.0%,CD:36.6%).Age at presentation did not affect the likelihood of EIM.Prevalence of EIMs was higher in women and in CD,ocular complications and primary sclerosing cholangitis (PSC) were more frequent in UC.In UC there was an increased tendency of EIM in patients with a more extensive disease.Joint complications were more frequent in CD (22.4% vsUC 10.2%,P<0.01).In UC positive family history increased the risk of joint complications (OR:3.63).In CD the frequency of type-1 peripheral arthritis was increased in patients with penetrating disease (P=0.028).PSC was present in 1.6% in UC and 0.8% in CD.Dermatological complications were present in 3.8% in UC and 10.2% in CD,the rate of ocular complications was around 3% in both diseases.Rare complications were glomerulonephritis,autoimmune hemolytic anaemia and celiac disease. CONCLUSION:Prevalence of EIM in Hungarian IBD patients is in concordance with data from Western countries.The high number of EIM supports a role for complex follow-up in these patients.展开更多
This report presents a survey of current knowledge concerning one of the relatively frequent and severe complications of liver cirrhosis and associated ascites-spontaneous bacterial peritonitis. Epidemiology,aetiology...This report presents a survey of current knowledge concerning one of the relatively frequent and severe complications of liver cirrhosis and associated ascites-spontaneous bacterial peritonitis. Epidemiology,aetiology,pathogenesis,clinical manifestation,diagnosis and present possibilities of treatment are discussed.展开更多
AIM： To investigate the effect of chronic inflammatory bowel disease （CIBD） specific risk factors for cholecystolithiasis, as duration and involvement pattern of the disease and prior surgery in patients with Crohn...AIM： To investigate the effect of chronic inflammatory bowel disease （CIBD） specific risk factors for cholecystolithiasis, as duration and involvement pattern of the disease and prior surgery in patients with Crohn＇s disease （CD） and ulcerative colitis （UC）. METHODS： A total of 222 patients with CD （135 females, 87 males, average age, 35.8±11.8 years; range 17-81 years） and 88 patients with UC （39 females, 49 males; average age, 37.2±13.6 years; range 16-81 years） underwent clinical and ultrasound examinations. Besides age, sex and degree of obesity, patients＇ CIBD specific parameters, including duration and extent of disease and prior operations were documented and evaluated statistically using logistic regression. RESLTLTS： The overall prevalence of gallbladder stone disease in patients with CD was 13% （n = 30）. Only age could be shown to be an independent risk factor （P = 0.014）. Compared to a collective representative for the general population in the same geographic region, the prevalence of cholecystolithiasis was higher in all corresponding age groups. Patients with UC showed an overall prevalence of gallbladder stone disease of only 4.6%. CONCLUSION：Only age but not disease-specific factors such as duration and extent of disease, and prior surgery are independent risk factors for the development of cholecystolithiasis in patients with CIBD.展开更多
文摘Objective: To evaluate the effects of dietary factors on cancer and non-communicable diseases. Methods: A correlation analysis between the consumption of various indicator food and mortality rates of cancer or non-communicable diseases was conducted by collecting secondary data from national nutrition surveys in Japan. Results: The consumption of cereal foods, plant energy and plant protein showed a significant negative correlation with mortality of cancer, heart diseases and diabetes; negatively related to the lung cancer and colon cancer in both sexes; a strong negative correlation with mortality of rectum cancer, liver cancer and prostate cancer in males, and of breast cancer in females; and a significant positive correlation with the stomach cancer in both sexes. The consumption of animal foods, animal energy, animal protein and fat showed a strong positive correlation with cancer, heart diseases and diabetes; a positive relations to lung cancer and colon cancer in both sexes, and rectum cancer, liver cancer and prostate cancer in males and breast cancer in females. On the contrary, a strong negative correlation was found in stomach cancer in both sexes; and esophagus cancer, liver cancer and uterus cancer in females. The consumption of vegetables and fruits showed a weak negative correlation with stomach cancer. Conclusion : The results suggest that diet not only plays a significant role in increasing the risks of some kinds of cancer or non-communicable diseases but also has a preventive effect. It is very important that dietary balance should be emphasized to prevent cancer and non-com-municable diseases.
文摘Objectives: To compare multiplex fluorescent PCRwith serum type-specific antibody detection in thediagnosis of herpes simplex virus (HSV) infection andto evaluate its significance in the diagnosis of genitalherpes.Methods: We detected HSV infection in 121 speci-mens collected from patients with genital herpesusing both multiplex fluorescent PCR and serum type-specific antibody detection. HSV viral isolation wasused as the standard control.Results: When compared with the viral isolation, thesensitivity and specificity for multiplex fluorescentPCR were 100% and 88.89%, respectively afterdiscrepant analysis. The sensitivity and specificity fortype-specific antibody detection was 77.68 % and77.78 %, respectively. However, the type-specificantibody detected HSV in two asymptomatic patientswhile the multiplex fluorescent PCR couldn’t detectany HSV DNA from those specimens.Conclusions: Multiplex fluorescent PCR is a verysensitive and specific method for detection and typingof HSV in the lesion of genital herpes, it failed todetect HSV DNA from the asymptomatic patients.Serum type-specific antibody detection was a lesssensitive and specific test but could detect the specificantibody from some asymptomatic patients. Thecombination of these two techniques would allow rapid,sensitive and accurate detection and typing of HSVand help clinical diagnosis and epidemiologic survey-ing of genital herpes.
文摘AIM:IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs).Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study. METHODS:Eight hundred and seventy-three IBD patients were enrolled (ulcerative colitis/UC/:619,m/f:317/302, mean age at presentation:38.3 years,average disease duration:11.2 years;Crohn's disease/CD/:254,m/f:125/129, mean age at presentation:32.5 years,average disease duration:9.2 years).Intestinal,extraintestinal signs and laboratory tests were monitored regularly.Any alteration suggesting an EIMs was investigated by a specialist. RESULTS:A total of 21.3% of patients with IBD had EIM (UC:15.0%,CD:36.6%).Age at presentation did not affect the likelihood of EIM.Prevalence of EIMs was higher in women and in CD,ocular complications and primary sclerosing cholangitis (PSC) were more frequent in UC.In UC there was an increased tendency of EIM in patients with a more extensive disease.Joint complications were more frequent in CD (22.4% vsUC 10.2%,P<0.01).In UC positive family history increased the risk of joint complications (OR:3.63).In CD the frequency of type-1 peripheral arthritis was increased in patients with penetrating disease (P=0.028).PSC was present in 1.6% in UC and 0.8% in CD.Dermatological complications were present in 3.8% in UC and 10.2% in CD,the rate of ocular complications was around 3% in both diseases.Rare complications were glomerulonephritis,autoimmune hemolytic anaemia and celiac disease. CONCLUSION:Prevalence of EIM in Hungarian IBD patients is in concordance with data from Western countries.The high number of EIM supports a role for complex follow-up in these patients.
基金Supported by The research project: NR 9310-3, Internal Grant Agency, Ministry of Health and research grant MSM 6198959223, Ministry of Education, Czech Republic
文摘This report presents a survey of current knowledge concerning one of the relatively frequent and severe complications of liver cirrhosis and associated ascites-spontaneous bacterial peritonitis. Epidemiology,aetiology,pathogenesis,clinical manifestation,diagnosis and present possibilities of treatment are discussed.
文摘AIM： To investigate the effect of chronic inflammatory bowel disease （CIBD） specific risk factors for cholecystolithiasis, as duration and involvement pattern of the disease and prior surgery in patients with Crohn＇s disease （CD） and ulcerative colitis （UC）. METHODS： A total of 222 patients with CD （135 females, 87 males, average age, 35.8±11.8 years; range 17-81 years） and 88 patients with UC （39 females, 49 males; average age, 37.2±13.6 years; range 16-81 years） underwent clinical and ultrasound examinations. Besides age, sex and degree of obesity, patients＇ CIBD specific parameters, including duration and extent of disease and prior operations were documented and evaluated statistically using logistic regression. RESLTLTS： The overall prevalence of gallbladder stone disease in patients with CD was 13% （n = 30）. Only age could be shown to be an independent risk factor （P = 0.014）. Compared to a collective representative for the general population in the same geographic region, the prevalence of cholecystolithiasis was higher in all corresponding age groups. Patients with UC showed an overall prevalence of gallbladder stone disease of only 4.6%. CONCLUSION：Only age but not disease-specific factors such as duration and extent of disease, and prior surgery are independent risk factors for the development of cholecystolithiasis in patients with CIBD.
