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基于DNS的感染主机分布监测技术研究
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作者 王辉 郭延文 +1 位作者 王世晋 牛博威 《信息安全研究》 2019年第4期327-332,共6页
基于DNS的技术原理,通过各节点部署DNS节点监测系统,监测并分析各节点解析控制端目标域名的DNS的响应数据,多次尝试探测并对数据进行建模分析,最终获取感染主机的地区分布情况和感染木马类型.并通过优化的节点管理调度方案,在不借助第... 基于DNS的技术原理,通过各节点部署DNS节点监测系统,监测并分析各节点解析控制端目标域名的DNS的响应数据,多次尝试探测并对数据进行建模分析,最终获取感染主机的地区分布情况和感染木马类型.并通过优化的节点管理调度方案,在不借助第三方手段情况下掌握某种病毒的爆发情况,对病毒发作的预防和溯源都有很好的作用,进一步形成全球范围的病毒感染风险监测态势. 展开更多
关键词 僵尸网络 远控木马 威胁情报 感染主机 恶意域名
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无尺度网络下具有免疫特征的僵尸网络传播模型 被引量:4
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作者 黄彪 谭良 +1 位作者 欧阳晨星 成淑萍 《计算机应用研究》 CSCD 北大核心 2012年第3期1028-1031,共4页
结合无尺度的特性,考虑僵尸网络传播过程中部分主机的免疫特性,提出一种无尺度网络下具有免疫特征的僵尸网络传播模型。该模型基于Internet的实际情况,重点考虑了无尺度网络的拓扑结构,并结合了僵尸网络中部分脆弱主机由于提前从易感染... 结合无尺度的特性,考虑僵尸网络传播过程中部分主机的免疫特性,提出一种无尺度网络下具有免疫特征的僵尸网络传播模型。该模型基于Internet的实际情况,重点考虑了无尺度网络的拓扑结构,并结合了僵尸网络中部分脆弱主机由于提前从易感染的网络中被移除而具有免疫特征的情况。通过MATLAB进行仿真,仿真结果表明,这种传播模型更符合真实网络中僵尸网络的传播规律。 展开更多
关键词 无尺度网络 僵尸网络 僵尸程序 感染主机 传播模型 免疫特征
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Global Transcriptional Profile of Tranosema rostrale Ichnovirus Genes in Infected Lepidopteran Hosts and Wasp Ovaries
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作者 Asieh Rasoolizadeh Frédéric Dallaire +3 位作者 Don Stewart Catherine Béliveau Renée Lapointe Michel Cusson 《Virologica Sinica》 SCIE CAS CSCD 2009年第5期478-492,共15页
The ichnovirus TrIV, transmitted by the endoparasitic wasp Tranosema rostrale to its lepidopteran host during oviposition, replicates asymptomatically in wasp ovaries and causes physiological dysfunctions in parasitiz... The ichnovirus TrIV, transmitted by the endoparasitic wasp Tranosema rostrale to its lepidopteran host during oviposition, replicates asymptomatically in wasp ovaries and causes physiological dysfunctions in parasitized caterpillars. The need to identify ichnoviral genes responsible for disturbances induced in lepidopteran hosts has provided the impetus for the sequencing and annotation of ichnovirus genomes, including that of TrIV. In the latter, 86 putative genes were identified, including 35 that could be assigned to recognized ichnoviral gene families. With the aim of assessing the relative importance of each TrIV gene, as inferred from its level of expression, and evaluating the accuracy of the gene predictions made during genome annotation, the present study builds on an earlier qPCR quantification of transcript abundance of TrIV rep ORFs, in both lepidopteran and wasp hosts, extending it to other gene families as well as to a sample of unassigned ORFs. We show that the majority (91%) of putative ORFs assigned to known gene families are expressed in infected larvae, while this proportion is lower (67%) for a sample taken among the remaining ORFs. Selected members of the TrV and rep gene families are shown to be transcribed in infected larvae at much higher levels than genes from any other TrIV gene family, pointing to their likely involvement in host subjugation. In wasp ovaries, the transcriptional profile is dominated by a rep gene and a member of a newly described gene family encoding secreted proteins displaying a novel cysteine motif, which we identified among previously unassigned ORFs. 展开更多
关键词 POLYDNAVIRUS Ichnovirus Choristoneura fumiferana Tranosema rostrale Transcriptional analysis
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Stress Granule Formation is One of the Early Antiviral Mechanisms for Host Cells Against Coxsackievirus B Infection 被引量:2
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作者 Xia Zhai Shuo Wu +8 位作者 Lexun Lin Tianying Wang Xiaoyan Zhong Yang Chen Weizhen Xu Lei Tong Yan Wang Wenran Zhao Zhaohua Zhong 《Virologica Sinica》 SCIE CAS CSCD 2018年第4期314-322,共9页
Stress granules(SGs) are intracellular granules formed when cellular translation is blocked and have been reported to be involved in a variety of viral infections. Our previous studies revealed that SGs are involved i... Stress granules(SGs) are intracellular granules formed when cellular translation is blocked and have been reported to be involved in a variety of viral infections. Our previous studies revealed that SGs are involved in the coxsackievirus B(CVB)infection process, but the role of SGs in CVB infection has not been fully explored. In this study, we found that CVB type 3(CVB3) could induce SG formation in the early phase of infection. Results showed that levels of CVB3 RNA and protein were significantly inhibited during the early stage of CVB3 infection by the elevated formation of SGs, while viral RNA and protein synthesis were significantly promoted when SG formation was blocked. Our findings suggest that SG formation is one of the early antiviral mechanisms for host cells against CVB infection. 展开更多
关键词 Coxsackievirus B (CVB) Stress granule (SG) Viral replication
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