Deve 1933年首先建立的实验性继发性包虫病动物模型,是研究包虫病的重要方法之一。为了解新疆人体细粒惊球蚴对不同种系小鼠的易感性,筛选理想的小鼠种系,建立包虫实验动物模型,我们采用该法,对长爪沙鼠、C<sub>57</sub>BL...Deve 1933年首先建立的实验性继发性包虫病动物模型,是研究包虫病的重要方法之一。为了解新疆人体细粒惊球蚴对不同种系小鼠的易感性,筛选理想的小鼠种系,建立包虫实验动物模型,我们采用该法,对长爪沙鼠、C<sub>57</sub>BL/6J、NIH相杂交小鼠4个种系鼠类,进行腹腔接种试验,观察小鼠的包虫感染情况。展开更多
Objective: To examine the association between chronic infection and cumulative burden of infection and acute coronary syndrome. Design: The 5C(Cork coronary care case-control)-study was a community based case-control ...Objective: To examine the association between chronic infection and cumulative burden of infection and acute coronary syndrome. Design: The 5C(Cork coronary care case-control)-study was a community based case-control study. Patients and controls underwent a standard physical examination and had blood samples taken for serological analysis for Helicobacter pylori(IgG), Chlamydia pneumoniae(IgA, IgM, and IgG), cytomegalovirus(IgG), and herpes simplex virus types 1 and 2(IgG). Setting: Patients were recruited from four hospitals in Cork City and Mal lowTown, Controls, individually matched on age and sex, were selected by incident density sampling from the same general practices as the referent case. Main outcome measures: Age and sex adjusted and fully adjusted odds ratios for acute coronary syndrome by seropositivity and by increasing number of infections. Results: Cases and controls did not differ significantly in seropositivity to C pneumoniae, cytomegalovirus, herpes simplex viruses, and H pylori. In unconditional logistic regression analysis adjusted for age, sex, waist to hip ratio, smoking, physical activity, alcohol consumption, and social class there was no evidence of an increasing risk for acute coronary syndrome with increasing burden of infection. Conclusions: The findings do not support an association between specific infectious agents and acute coronary syndrome and do not provide evidence of a burden of infection effect.展开更多
文摘Objective: To examine the association between chronic infection and cumulative burden of infection and acute coronary syndrome. Design: The 5C(Cork coronary care case-control)-study was a community based case-control study. Patients and controls underwent a standard physical examination and had blood samples taken for serological analysis for Helicobacter pylori(IgG), Chlamydia pneumoniae(IgA, IgM, and IgG), cytomegalovirus(IgG), and herpes simplex virus types 1 and 2(IgG). Setting: Patients were recruited from four hospitals in Cork City and Mal lowTown, Controls, individually matched on age and sex, were selected by incident density sampling from the same general practices as the referent case. Main outcome measures: Age and sex adjusted and fully adjusted odds ratios for acute coronary syndrome by seropositivity and by increasing number of infections. Results: Cases and controls did not differ significantly in seropositivity to C pneumoniae, cytomegalovirus, herpes simplex viruses, and H pylori. In unconditional logistic regression analysis adjusted for age, sex, waist to hip ratio, smoking, physical activity, alcohol consumption, and social class there was no evidence of an increasing risk for acute coronary syndrome with increasing burden of infection. Conclusions: The findings do not support an association between specific infectious agents and acute coronary syndrome and do not provide evidence of a burden of infection effect.
