期刊文献+
共找到8篇文章
< 1 >
每页显示 20 50 100
小剂量阿司匹林对慢性前庭神经炎引起的眩晕的影响
1
作者 孙一华 李晓静 《中国科技期刊数据库 医药》 2024年第9期0055-0058,共4页
探究小剂量阿司匹林对慢性前庭神经炎引起的眩晕的治疗效果。方法 选择104名患者,随机分为对照组和观察组,每组52名,对照组给予常规治疗,观察组在常规治疗基础上增加小剂量阿司匹林治疗。结果 经过治疗,观察组的脑血流速度显著提高,治疗... 探究小剂量阿司匹林对慢性前庭神经炎引起的眩晕的治疗效果。方法 选择104名患者,随机分为对照组和观察组,每组52名,对照组给予常规治疗,观察组在常规治疗基础上增加小剂量阿司匹林治疗。结果 经过治疗,观察组的脑血流速度显著提高,治疗后Vp,Vd,Vm和PI值分别为:149.88±5.45cm/s,85.49±5.59cm/s,113.58±4.13cm/s,1.16±0.19,临床症状的消失时间也显著少于对照组(头痛消失时间33.54±4.37天,头晕消失时间33.59±5.80天)。对比两组治疗后脑血管事件发生率,观察组的总发病率(1.92%)明显低于对照组(17.3%)。两组在治疗过程中出现的不良反应比例差异无统计学意义。结论 小剂量阿司匹林可以显著提高患者的脑血流速度,缩短症状消失时间,同时,也降低了脑血管事件的发生率,为慢性前庭神经炎引起的眩晕提供了一个有效的治疗手段。 展开更多
关键词 小剂量阿司匹林 慢性前庭神经炎 眩晕治疗 脑血流速度 脑血管事件发生率
下载PDF
关注带状疱疹与带状疱疹后神经痛的病理改变:病毒引起的急性与慢性神经炎 被引量:4
2
作者 赵森明 《中华疼痛学杂志》 2022年第3期291-292,共2页
带状疱疹是感觉神经内水痘-带状疱疹病毒(VZV)感染引起的急性神经炎,带状疱疹后神经痛(PHN)是带状疱疹迁延不愈导致的慢性感觉神经炎性疾病。
关键词 带状疱疹 神经 带状疱疹后 神经病理性疼痛 慢性神经炎 躯体感觉神经损伤
原文传递
参苓白术散治疗职业中毒性慢性末梢神经炎经验 被引量:1
3
作者 唐晓华 《中医研究》 2011年第3期47-48,共2页
参苓白术散出自《太平惠民和剂局方》,具有益气健脾、渗湿和胃止泻之效,主治脾胃虚弱而夹湿之证。笔者在临证时常采用此方加减治疗多种职业中毒引起的慢性末梢神经炎,总结经验如下。
关键词 参苓白术散/治疗应用 职业中毒性慢性末梢神经炎/治疗中医药疗法
下载PDF
Antidepressant effects of Yuanzhi (Polygalae Radix) extract on chronic unpredictable mild stress-induced depression in rats: modulation of the NLRP3 inflammasome and NF-κB pathway
4
作者 CHEN Yuzhen ZHAO Yongzhi +4 位作者 ZHANG Yiwen CHEN Fang Iqbal Choudhary Muhammad LIU Xinmin JIANG Ning 《Digital Chinese Medicine》 CAS CSCD 2024年第2期184-194,共11页
Objective To investigate the antidepressant effects of Yuanzhi(Polygalae Radix;PR)aqueous extract on chronic unpredictable mild stress(CUMS)-induced depression rat models and the underlying mechanisms.Methods A total ... Objective To investigate the antidepressant effects of Yuanzhi(Polygalae Radix;PR)aqueous extract on chronic unpredictable mild stress(CUMS)-induced depression rat models and the underlying mechanisms.Methods A total of 40 male Sprague Dawley(SD)rats were randomly divided into control;model;low dose of PR(PR-L;0.5 g/kg);high dose of PR(PR-H;1 g/kg);and fluoxetine(10 mg/kg)groups;with 8 rats in each group.Except for the rats in control group;those in the other four groups underwent CUMS-induced depression modeling.PR and fluoxetine were administered intragastrically once daily;30 min prior to the CUMS procedure;for 14 consecu-tive days until the behavioral tests were performed.After CUMS modeling;the sucrose prefer-ence test(SPT);open field test(OFT);novelty-suppressed feeding test(NSFT);forced swim test(FST);and tail suspension test(TST)were employed to assess the pharmacological ef-fects of PR on the mitigation of depressive-like behaviors in rat models.Additionally;the en-zyme-linked immunosorbent assay(ELISA)was utilized to quantify the serum levels of tumor necrosis factor(TNF)-α;interleukin(IL)-6;and IL-1βin the rats.Western blot analysis was al-so conducted to evaluate the protein expression levels of nuclear factor kappa-B(NF-κB);in-ducible nitric oxide synthase(iNOS);cyclooxygenase-2(COX-2);nucleotide-binding oligomerization domain(NOD)-like receptor family pyrin domain containing 3(NLRP3);apoptosis-associated speck-like protein containing caspase recruitment domain(ASC);and caspase-1 in the hippocampal tissues of the rats.Immunofluorescence staining was per-formed to observe the morphological changes in ionized calcium-binding adapter molecule 1 positive(Iba-1+)cells in the dentate gyrus(DG)of rats with CUMS-induced depression.Results(i)Treatment with PR-H and fluoxetine resulted in significant enhancements in both the total distance and time the rats moved during tests(P<0.01 and P<0.05;respectively).Post-administration of PR-H and fluoxetine also led to statistically significant increase in su-crose preference among rats(P<0.05).Besides;PR-L;PR-H;and fluoxetine treatment markedly decreased the latency of ingestion(P<0.05;P<0.05;and P<0.01;respectively).As observed from the FST;PR-L;PR-H;and fluoxetine presented antidepressant effects on rats with CUMS-induced depression;leading to the reduction in time of their immobility(P<0.05;P<0.01;and P<0.01;respectively).The results of TST indicated reduced immobility time in rats receiving PR-H and fluoxetine treatment as well(P<0.01).(ii)Rats in model group showed an increase in the levels of Iba-1+microglia in their left and right brains in compari-son with control group(P<0.01).However;such increase was negated post PR treatment(P<0.01).Treatment with PR-L;PR-H;and fluoxetine considerably reduced the levels of inflam-matory factors(TNF-α;IL-1β;and IL-6;P<0.01).In addition;treatment of PR-L and PR-H ef-fectively counteracted the elevated levels of NLRP3;ASC;and caspase-1;and markedly down-regulated the expression levels of phosphorylated p65(p-p65);COX-2;and iNOS in rats’hip-pocampus(P<0.01).Conclusion Collectively;these findings indicate that PR exerts an antidepressant effect on rats with CUMS-induced depression partially through the modulation of the NLRP3 and NF-κB signaling pathways. 展开更多
关键词 DEPRESSION Yuanzhi(Polygalae Radix) Chronic unpredictable mild stress(CUMS) Proinflammatory cytokine Neuroinflammatory
下载PDF
红外线治疗灯临床应用进展 被引量:2
5
作者 蒲娟 张广生 蒲万玉 《中国社区医师(医学专业)》 2004年第8期8-8,共1页
红外线治疗灯过去传统用于照射治疗慢性神经炎、肌炎、纤维组织炎及关节炎、关节扭伤、挫伤、骨折和关节脱臼后软组织肿胀等。近年来我院采用YSHD-1型上海跃进医用光学器械厂生产的立地式红外线治疗灯局部照射治疗手术切口延迟愈合11例... 红外线治疗灯过去传统用于照射治疗慢性神经炎、肌炎、纤维组织炎及关节炎、关节扭伤、挫伤、骨折和关节脱臼后软组织肿胀等。近年来我院采用YSHD-1型上海跃进医用光学器械厂生产的立地式红外线治疗灯局部照射治疗手术切口延迟愈合11例,小面积浅Ⅱ°烫伤21例.外伤感染创面16例.带状疱疹125例,现总结如下。 展开更多
关键词 红外线治疗灯 照射治疗 慢性神经炎 肌炎
下载PDF
Is the pain in chronic pancreatitis of neuropathic origin? Support from EEG studies during experimental pain 被引量:5
6
作者 AsbjФrn M Drewes Maciej Gratkowski +3 位作者 Saber AK Sami Georg Dimcevski Peter Funch-Jensen Lars Arendt-Nielsen 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第25期4020-4027,共8页
AIM: To prove the hypothesis that patients with chronic pancreatitis would show increased theta activity during painful visceral stimulation. METHODS: Eight patients and 12 healthy controls underwent an experiment whe... AIM: To prove the hypothesis that patients with chronic pancreatitis would show increased theta activity during painful visceral stimulation. METHODS: Eight patients and 12 healthy controls underwent an experiment where the esophagus was electrically stimulated at the pain threshold using a nasal endoscope. The electroencephalogram (EEG) was recorded from 64 surface electrodes and "topographic matching pursuit" was used to extract the EEG information in the early brain activation after stimulation. RESULTS: A major difference between controls and patients were seen in delta and theta bands, whereas there were only minor differences in other frequency bands. In the theta band, the patients showed higher activity than controls persisting throughout the 450 ms of analysis with synchronous brain activation betweenthe channels. The main theta components oscillated with 4.4 Hz in the patients and 5.5 Hz in the controls. The energy in the delta (0.5-3.5 Hz) band was higher in the controls, whereas the patients only showed scattered activity in this band. CONCLUSION: The differences in the theta band indicate that neuropathic pain mechanisms are involved in chronic pancreatitis. This has important implications for the understanding and treatment of pain in these patients, which should be directed against drugs with effects on neuropathic pain disorders. 展开更多
关键词 Chronic Pancreatitis Neuropathic pain ESOPHAGUS Thalamocortical system Electroence-phalography
下载PDF
Effect of NCPB and VSPL on pain and quality of life in chronic pancreatitis patients 被引量:10
7
作者 Andrzej Basinski Tomasz Stefaniak +5 位作者 Ad Vingerhoets Wojciech Makarewicz Lukasz Kaska Aleksander Stanek Andrzej J.Lachinski Zbigniew Sledzinski 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第32期5010-5014,共5页
AIM: To compare the effects of neurolytic celiac plexus block (NCPB) and videothoracoscopic splanchnicectomy (VSPL) on pain and quality of life of chronic pancreatitis (CP) patients.METHODS: Forty-eight small duct CP ... AIM: To compare the effects of neurolytic celiac plexus block (NCPB) and videothoracoscopic splanchnicectomy (VSPL) on pain and quality of life of chronic pancreatitis (CP) patients.METHODS: Forty-eight small duct CP patients were treated invasively with NCPB (n = 30) or VSPL (n = 18) in two non-randomized, prospective, case-controlled protocols due to chronic pain syndrome, and compared to a control group who were treated conservatively (n = 32). Visual analog scales were used to assess pain and opioid consumption rate was evaluated. In addition, the quality of life was measured using QLQ C-30 for NCPB and FACIT for VSPL.Although both questionnaires covered similar problems,they could not be compared directly one with another.Therefore, the studies were compared by meta-analysis methodology.RESULTS: Both procedures resulted in a significant positive effect on pain of CP patients. Opioids were withdrawn totally in 47.0% of NCPB and 36.4% of VSPL patients,and reduced in 53.0% and 45.4% of the respective patient groups. No reduction in opioid usage was observed in the control group. In addition, fatigue and emotional well-being showed improvements. Finally, NCPB demonstrated stronger positive effects on social support, which might possibly be attributed to earlier presentation of patients treated with NCPB.CONCLUSION: Both invasive pain treatment methods are effective in CP patients with chronic pain. 展开更多
关键词 Chronic pancreatitis PAIN Neurolytic celiac plexus block Videothoracoscopic splanchnicectomy Quality of life
下载PDF
Gamunex
8
作者 黄艳(编译) 《中国处方药》 2008年第10期18-18,共1页
美国FDA近日宣布,批准Talecris Biotherapeutics公司的免疫球蛋白产品Gamunex(immune globulin)用于慢性脱髓鞘性多发性神经炎(CIDP)的治疗。这是一种罕见的自体免疫性疾病,其代表特征是四肢进行性萎缩无力并伴有传导功能受损。
关键词 慢性脱髓鞘性多发性神经炎 症状 治疗方法 免疫球蛋白
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部