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急性菌痢所致慢性肠炎发病机制和药物治疗 被引量:16
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作者 胡荣杉 谢平 《中国医药指南》 2011年第32期342-343,共2页
目的探讨急性细菌性痢疾和急性消化不良所引起的慢性肠炎发病机制,并采取系统的治疗以根治。方法针对这种病情,我院采取一种特殊治疗方法即中西药结合增加胃肠消化功能,辅以抗菌消炎药抑制致病菌达到标本兼治。结果经过治疗,有效率达到9... 目的探讨急性细菌性痢疾和急性消化不良所引起的慢性肠炎发病机制,并采取系统的治疗以根治。方法针对这种病情,我院采取一种特殊治疗方法即中西药结合增加胃肠消化功能,辅以抗菌消炎药抑制致病菌达到标本兼治。结果经过治疗,有效率达到95%,治愈率达到85%。讨论通过对急性细菌性痢疾和急性消化不良所致的慢性肠炎患者发病机制,采用标本兼治的方法,为慢性肠炎的治疗做了很好的范例。 展开更多
关键词 慢性肠炎/发病机制 中西药物结合 治疗
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Etiopathogenesis of inflammatory bowel diseases 被引量:61
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作者 Silvio Danese Claudio Fiocchi 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第30期4807-4812,共6页
Theories explaining the etiopathogenesis of inflammatory bowel disease (IBD) have been proposed ever since Crohn's disease (CD) and ulcerative colitis (UC) were recognized as the two major forms of the disease.... Theories explaining the etiopathogenesis of inflammatory bowel disease (IBD) have been proposed ever since Crohn's disease (CD) and ulcerative colitis (UC) were recognized as the two major forms of the disease. Although the exact cause(s) and mechanisms of tissue damage in CD and UC have yet to be completely understood, enough progress has occurred to accept the following hypothesis as valid: IBD is an inappropriate immune response that occurs in genetically susceptible individuals as the result of a complex interaction among environmental factors, microbial factors, and the intestinal immune system. Among an almost endless list of environmental factors, smoking has been identified as a risk factor for CD and a protective factor for UC. Among microbial factors, no convincing evidence indicates that classical infectious agents cause IBD, while mounting evidence points to an abnormal immune response against the normal enteric flora as being of central importance. Gut inflammation is mediated by cells of the innate as well as adaptive immune systems, with the additional contribution of non-immune cells, such as epithelial, mesenchymal and endothelial cells, and platelets. 展开更多
关键词 Inflammatory bowel disease Chronic inflammation Mucosal immunity Innate immunity Adaptive immunity ENVIRONMENT Commensal flora
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