目的检测慢性肺源性心脏病(简称“肺心病”)患者中肌少症的患病率,及其对预后的影响。方法选取2023年1月至2024年1月在天津市第一中心医院呼吸与危重症医学科住院的肺心病患者120例作为研究组,同时选取2023年1月至2024年1月在天津市第...目的检测慢性肺源性心脏病(简称“肺心病”)患者中肌少症的患病率,及其对预后的影响。方法选取2023年1月至2024年1月在天津市第一中心医院呼吸与危重症医学科住院的肺心病患者120例作为研究组,同时选取2023年1月至2024年1月在天津市第一中心医院健康查体科查体的老年人群108名作为对照组,测定患者肢体骨骼肌的含量,6 m日常步速和握力测试。测定肺心病患者合并肌少症的患病率、血气分析、血清白蛋白值。结果研究组肌少症的患病率(55.00%)高于对照组(12.04%),差异有统计学意义(P<0.001)。研究组合并肌少症患者相比未合并肌少症患者血气分析酸碱度(power of hydrogen,pH)值、氧分压(PO2)较低,二氧化碳分压(PCO_(2))较高,差异均有统计学意义(P<0.05)。研究组合并肌少症患者相比未合并肌少症患者血清白蛋白水平较低,差异有统计学意义(P<0.001)。结论肺心病患者中肌少症患病率升高,肺心病合并肌少症患者的血气分析呼吸性酸中毒加重,血清白蛋白水平较低,将显著影响患者预后。展开更多
慢性肺源性心脏病(Chronic Pulmonary Heart Disease, CPHD,简称为肺心病)是一种临床常见且与呼吸系统疾病密切相关的心脏疾病。主要是由于各种原因(如胸廓、支气管、肺组织或肺血管病变)致肺血管阻力增加,产生肺动脉高压,右心室后负荷...慢性肺源性心脏病(Chronic Pulmonary Heart Disease, CPHD,简称为肺心病)是一种临床常见且与呼吸系统疾病密切相关的心脏疾病。主要是由于各种原因(如胸廓、支气管、肺组织或肺血管病变)致肺血管阻力增加,产生肺动脉高压,右心室后负荷增大,导致其结构或(和)功能改变,其核心病理环节是肺动脉高压,其发病的病理基础是肺泡慢性缺氧,引起肺血管收缩、重构,血容量增多、血液黏稠度增加,最终肺动脉高压形成。CPHD已逐渐成为全世界关注的公共卫生问题,给患者生活质量和家庭带来了严重的负担。该病常反复发作,病死率高,是严重危害人类健康,影响人民幸福的疾病。故本文主要从西医发病机制、中医病因病机两方面来简述CPHD的研究概况。Chronic Pulmonary Heart Disease (CPHD) is a clinically common heart disease closely related to respiratory diseases. Mainly due to various reasons (such as chest, bronchus, lung tissue or pulmonary vascular diseases), pulmonary hypertension is caused by increased pulmonary vascular resistance, and the right ventricular afterload increases, resulting in changes in its structure or (and) function. The core pathological link is pulmonary hypertension, and its pathological basis is chronic alveolar hypoxia, which causes pulmonary vascular contraction and remodeling. Blood volume increases, blood viscosity increases, and eventually pulmonary hypertension develops. CPHD has gradually become a public health problem of worldwide concern, which brings serious burden to the quality of life of patients and families. The disease is often repeated, the fatality rate is high, is a serious harm to human health, affect people’s happiness of the disease. Therefore, this paper mainly summarizes the research situation of CPHD from two aspects: Pathogenesis of Western medicine and etiology and pathogenesis of Chinese medicine.展开更多
文摘目的检测慢性肺源性心脏病(简称“肺心病”)患者中肌少症的患病率,及其对预后的影响。方法选取2023年1月至2024年1月在天津市第一中心医院呼吸与危重症医学科住院的肺心病患者120例作为研究组,同时选取2023年1月至2024年1月在天津市第一中心医院健康查体科查体的老年人群108名作为对照组,测定患者肢体骨骼肌的含量,6 m日常步速和握力测试。测定肺心病患者合并肌少症的患病率、血气分析、血清白蛋白值。结果研究组肌少症的患病率(55.00%)高于对照组(12.04%),差异有统计学意义(P<0.001)。研究组合并肌少症患者相比未合并肌少症患者血气分析酸碱度(power of hydrogen,pH)值、氧分压(PO2)较低,二氧化碳分压(PCO_(2))较高,差异均有统计学意义(P<0.05)。研究组合并肌少症患者相比未合并肌少症患者血清白蛋白水平较低,差异有统计学意义(P<0.001)。结论肺心病患者中肌少症患病率升高,肺心病合并肌少症患者的血气分析呼吸性酸中毒加重,血清白蛋白水平较低,将显著影响患者预后。
文摘慢性肺源性心脏病(Chronic Pulmonary Heart Disease, CPHD,简称为肺心病)是一种临床常见且与呼吸系统疾病密切相关的心脏疾病。主要是由于各种原因(如胸廓、支气管、肺组织或肺血管病变)致肺血管阻力增加,产生肺动脉高压,右心室后负荷增大,导致其结构或(和)功能改变,其核心病理环节是肺动脉高压,其发病的病理基础是肺泡慢性缺氧,引起肺血管收缩、重构,血容量增多、血液黏稠度增加,最终肺动脉高压形成。CPHD已逐渐成为全世界关注的公共卫生问题,给患者生活质量和家庭带来了严重的负担。该病常反复发作,病死率高,是严重危害人类健康,影响人民幸福的疾病。故本文主要从西医发病机制、中医病因病机两方面来简述CPHD的研究概况。Chronic Pulmonary Heart Disease (CPHD) is a clinically common heart disease closely related to respiratory diseases. Mainly due to various reasons (such as chest, bronchus, lung tissue or pulmonary vascular diseases), pulmonary hypertension is caused by increased pulmonary vascular resistance, and the right ventricular afterload increases, resulting in changes in its structure or (and) function. The core pathological link is pulmonary hypertension, and its pathological basis is chronic alveolar hypoxia, which causes pulmonary vascular contraction and remodeling. Blood volume increases, blood viscosity increases, and eventually pulmonary hypertension develops. CPHD has gradually become a public health problem of worldwide concern, which brings serious burden to the quality of life of patients and families. The disease is often repeated, the fatality rate is high, is a serious harm to human health, affect people’s happiness of the disease. Therefore, this paper mainly summarizes the research situation of CPHD from two aspects: Pathogenesis of Western medicine and etiology and pathogenesis of Chinese medicine.
