Quantum communications helps us to enhance the security and efficiency of communications and to deepen our understanding of quantum physics. Its rapid development in recent years has attracted the interest of research...Quantum communications helps us to enhance the security and efficiency of communications and to deepen our understanding of quantum physics. Its rapid development in recent years has attracted the interest of researchers from diverse fields such as physics, mathematics, and computer science. We review the background and current state of quantum communications technology, with an emphasis on quantum key distribution, quantum random number generation, and a relatively hot topic: device independent protocols.展开更多
As one of the largest global public health problems, cancer greatly endangers human health. Researchers have been committed to discovering anticancer drugs with high efficiency and low toxicity. Shogaol, a kind of ing...As one of the largest global public health problems, cancer greatly endangers human health. Researchers have been committed to discovering anticancer drugs with high efficiency and low toxicity. Shogaol, a kind of ingredient from ginger with high anti-tumor activity, has attracted our attention. This study was an investigation on the composition and structure-activity relationship of different analogues of shogaol, with the purpose to screen for shogaol compounds which had higher anti-tumor activity and could be easily synthesized. We chose zingerone as the starting material to synthesize shogaol through four-step reactions without protective group, as a result, 31 analogues were synthesized for anti-tumor activity detect. The biological test results showed that： the missing of the unsaturated ketone and the phenolic hydroxyl group reduced the anti-tumor activity of shogaol; the site of phenolic hydroxyl had no significant influence on the anti-tumor activity, the indicating that the larger the steric hindrance of substituent, the lower the activity, but the higher the activity of cyclobutyl substituted derivatives.展开更多
基金supported by the National Basic Research Program of China under Grants No. 2011CBA00200 No. 2011CB921200+2 种基金National Natural Science Foundation of China under Grants No. 60921091 No. 61101137 No. 61201239
文摘Quantum communications helps us to enhance the security and efficiency of communications and to deepen our understanding of quantum physics. Its rapid development in recent years has attracted the interest of researchers from diverse fields such as physics, mathematics, and computer science. We review the background and current state of quantum communications technology, with an emphasis on quantum key distribution, quantum random number generation, and a relatively hot topic: device independent protocols.
文摘As one of the largest global public health problems, cancer greatly endangers human health. Researchers have been committed to discovering anticancer drugs with high efficiency and low toxicity. Shogaol, a kind of ingredient from ginger with high anti-tumor activity, has attracted our attention. This study was an investigation on the composition and structure-activity relationship of different analogues of shogaol, with the purpose to screen for shogaol compounds which had higher anti-tumor activity and could be easily synthesized. We chose zingerone as the starting material to synthesize shogaol through four-step reactions without protective group, as a result, 31 analogues were synthesized for anti-tumor activity detect. The biological test results showed that： the missing of the unsaturated ketone and the phenolic hydroxyl group reduced the anti-tumor activity of shogaol; the site of phenolic hydroxyl had no significant influence on the anti-tumor activity, the indicating that the larger the steric hindrance of substituent, the lower the activity, but the higher the activity of cyclobutyl substituted derivatives.
