脑梗死急性期OCSP分型和磁共振成像分型对应关系研究

目的探讨脑梗死急性期OCSP分型与磁共振成像分型的对应关系。方法回顾性分析2009年3月～2011年2月收治的128例脑梗死急性期病人的临床资料,根据其临床体征和主要症状进行筛选与进行OCSP分型,并且分别对其进行CT成像、磁共振成像比较分析。分析OCSP分型与磁共振成像分型之间的对应关系。结果 93例患者的OCSP分型与磁共振成像分型一致,分型总准确率为73.03%。各亚型分型准确率分别为TACI78.6%(11/14)、PACI79.5%(31/39)、LACI70%(35/50)、POCI64%(16/25)。结论脑梗死急性期OCSP分型与磁共振成像分型的对应关系较为密切,有利于临床分型和指导治疗。

脑梗死急性期OCSP分型与磁共振成像分型的关系研究

目的:探讨研究脑梗死急性期OCSP分型和磁共振成像分型之间的关系。方法:回顾性分析150例脑梗死急性期患者的临床资料,分别对患者进行CT扫描和磁共振成像同时进行OCSP分型。对比分析OCSP分型和磁共振成像分型之间的关系。结果:分型结果显示OCSP分型和磁共振成像分型的平均准确率达到74.9%,OCSP分型和磁共振成像分型二者的差异并不显著,没有统计学意义(P>0.05)。结论:OCSP分型和磁共振成像分型有很好的对应关系,对于临床分型和治疗具有指导作用。

脑梗死急性期OCSP分型和磁共振成像分型对应关系研究

目的探讨脑梗死急性期OCSP分型和磁共振成像分型对应关系。方法分析100例脑梗死急性期患者临床资料,分别通过OCSP分型和磁共振成像分型。结果 OCSP分型和磁共振成像分型符合率较高,P<0.05,差异有统计学意义。结论根据临床表现快速的区分为明确特征的OCSP 4个亚型,这种方法简便、快速,可广泛应用于临床实践,由于其与预后和病变部位密切相关,从而为临床研究和治疗提供了依据。

CT门静脉成像分型个体化手术治疗在肝硬化门静脉高压症中的应用价值

目的:分析CT门静脉成像分型个体化手术治疗在肝硬化门静脉高压症中的应用价值。方法:选取2015年1月—2017年1月在我院行手术治疗的肝硬化门静脉高压症患者240例,随机分为分型组与对照组,各120例。分型组患者术前CTPV分型采取个体化手术方法,对照组行脾切除术+贲门周围血管离断术,对比两种手术方式患者术中和术后情况。结果:分型组的手术时间、术中出血量明显少于对照组,组间比较差异具有统计学意义;分型组的总体生存率明显高于对照组,组间比较差异具有统计学意义。讨论:在肝硬化门静脉高压症患者进行术前CTPV分型,可降低门静脉压力,对提高患者术后生存率作用显著。

放大窄带成像内镜JNET分型在结直肠肿瘤中的临床应用

目的:探讨放大窄带成像内镜日本窄带成像技术专家小组(JNET)分型在结直肠肿瘤诊断中的临床应用价值。方法:回顾性分析放大窄带成像内镜检查的106处结直肠肿瘤,并进行JNET分型,与内镜或外科手术标本病理诊断进行比较,评估JNET分型的准确性。结果:结肠肿瘤术后标本病理提示:非早癌病例70例,其中增生性息肉(包括锯齿状息肉)10例,低级别上皮内瘤变60例;早癌病例36例,其中高级别上皮内瘤变21例,黏膜下浅层癌7例,黏膜下深层癌8例。JNET各分型其准确性、特异性、敏感性、阳性预测值以及阴性预测值如下。1型:98.11%,98.96%,90.00%,90.00%,98.96%,2A型:80.19%,71.74%,86.67%,80.00%,80.49%;2B型:77.36%,84.62%,57.14%,57.14%,84.62%;3型:95.28%,100.00%,37.5%,100.00%,95.15%;JNET分型对结直肠病变早癌诊断的准确性、特异性、敏感性、阳性预测值及阴性预测值为:82.08%,90.00%,66.67%,77.42%,84.00%。结论:JNET分型能有效实时判断结直肠肿瘤性病变的良恶性程度,对部分诊断困难病变需结合放大染色内镜提高准确率。

基于NICE分型的结直肠小息肉诊断临床研究

目的探讨基于窄带成像国际结肠内窥镜(Narrow-band Imaging International Colorectal Endoscopic,NICE)分型的结直肠小息肉诊断临床价值。方法选取2019年1月—2020年9月武汉科技大学附属汉阳医院内镜中心200例进行肠镜检查发现小息肉(直径≤10 mm)的患者作为研究对象。入院后,均行窄带成像(Narrow Band Imaging,NBI)放大肠镜检查,观察病灶位置、形态特征。与“金标准”病理检查相比,观察NICE分型标准下病灶分型情况及诊断灵敏度、特异度、准确度、阳性预测值、阴性预测值。结果200例患者镜下共发现248个小息肉样病变,分布于直肠45个(18.15%)、横结肠61个(24.60%)、升结肠58个(23.39%)、乙状结肠40个(16.13%)、降结肠44个(17.74%);隆起型125个(50.40%)、平坦型病灶123个(49.60%)。病理学检查结果显示,248个小息肉样病变中,良性病灶191个(77.02%),恶性病灶57个(22.98%)。与病理检查相比,观察NICE分型标准下检出病灶灵敏度96.49%、特异度98.43%、准确度97.98%、阳性预测值94.83%、阴性预测值98.95%。结论结直肠小息肉样病变诊断中应用NICE分型法效果理想,可鉴别诊断息肉性质,了解息肉具体特征。

非放大内镜应用窄带成像国际结直肠内镜分型判定结直肠息肉样病变性质的临床价值

目的评价非放大内镜应用窄带成像国际结直肠内镜(NICE)分型判定结直肠息肉样病变性质的效能及其临床实用价值。方法选取2017年3月至2019年12月在上海市浦东新区公利医院消化内镜中心接受肠镜检查的患者286例,共计547处结直肠息肉样病变纳入分析。以病理诊断结果为标准,分别计算NICE分型判定结直肠息肉样病变性质的灵敏度、特异度、准确率、阳性预测值和阴性预测值,并与病理诊断结果及Sano分型结果进行对比分析及一致性检验。同时对经验组和普通组两组医师的诊断结果进行一致性评价。结果NICE分型判定结直肠息肉样病变病理分型的灵敏度、特异度、准确率、阳性预测值、阴性预测值分别为97.30%、87.88%、96.16%、98.32%、81.69%,判定≤0.5 cm病变病理分型的灵敏度、特异度、准确率、阳性预测值、阴性预测值分别为92.31%、87.23%、88.33%、66.67%、97.62%。NICE分型判定不同直径结直肠息肉样病变性质的灵敏度、特异度及准确率等比较差异均无统计学意义(均P>0.05)。NICE分型结果与病理诊断结果及Sano分型结果一致性均良好(Kappa=0.755、0.824,均P<0.01)。两组医师在诊断灵敏度、特异度、准确率等方面比较差异均无统计学意义(均P>0.05),组间观察一致性良好(Kappa=0.895,P<0.01)。结论非放大内镜应用NICE分型具有良好的判定结直肠息肉样病变性质的效能。建议仅将结直肠肿瘤性息肉纳入内镜下切除或外科手术治疗,而对于结直肠微小息肉(≤0.5 cm)可以执行“切除-丢弃”和“不切除”的这一内镜处置策略。

浆细胞性乳腺炎的MRI分型与中医证型的相关性

目的:探讨浆细胞性乳腺炎(PCM)的磁共振成像(MRI)分型与中医证型的相关性。方法:回顾性选取2019年1月~2022年2月在本院收治的PCM患者96例(96处病灶)作为PCM组,根据中医证型的不同将患者分为肝经蕴热证组(n=57)、余毒未清证组(n=39)。记录所有患者的中医证候积分,并分析不同中医证型的MRI分型、表现及时间-信号强度曲线(TIC)、ADC值。结果:肝经蕴热证组以乳房结块、红肿、乳头凹陷为主,余毒未清证组以乳房肿胀溃疡、脓水淋漓及乳头凹陷为主。肝经蕴热证组ADC值显著低于余毒未清证组(P<0.05),但TIC比较无明显差异(P>0.05)。肝经蕴热证组MRI表现以脓肿型为主占75.44%(43/57),T1W1为低信号,T2W1为高信号,增强扫描为脓肿环形,片状或蜂窝状,其次为炎症型24.56%(14/57),未见混合型。余毒未清证组以脓肿型和混合型为主,分别占56.41%(22/39)和43.59%(17/39),未见炎症型。肝经蕴热证组和余毒未清证组MRI分型对比有显著差异(P<0.05)。结论:PCM的MRI分型与中医证型可能在疾病进展过程中逐渐趋于一致,临床可通过MRI检查为中医辨证论治提供参考。

罗兰圆型二维集成凹面光栅的成像分析

利用标量波动衍射理论,通过对光栅槽面的数值积分,计算了罗兰圆型集成二维凹面光栅像点的光强分布.分析了工艺中的折射率偏差对光谱位置的影响,计算了光栅的色散和分辨力,并与几何光学的分析方法作了比较,分析了光栅的槽面数、光源的模场宽度以及因工艺产生的槽面圆角对光栅成像的影响;

基于粉刺性乳痈的MRI影像学特征的研究

目的:分析粉刺性乳痈磁共振成像(MRI)的影像特征,为临床手术治疗提供依据。方法:选取在医院诊治的27例粉刺性乳痈患者,均于术前行MRI增强扫描,根据患者临床表现的局限型、单纯型、复杂型的临床分型,观察分析与其相对应的MRI影像学表现。结果:27例患者临床表现为局限型、单纯型和复杂型三种临床分型。MRI影像下病灶于T1WI呈低信号或等信号;T2WI抑脂信号下呈高信号或等高信号,边界欠清晰,增强后病灶全部明确显示。其中局限型8例,局部皮肤无明显水肿增厚表现,增强扫描后病变明显强化,脓肿显示清晰;单纯型11例,患侧乳房较健侧明显增大,可见乳头内缩,增强后病变部位明显强化,脓肿清晰显影,脓腔范围较大,可见胸筋膜轻度强化;复杂型8例,增强扫描后病变明显强化,范围累及整个乳房。结论:MRI可清晰显示病变部位、侵犯范围和病情进展程度,可为手术治疗提供可靠依据。

胎盘植入41例宫腔镜电切治疗的临床研究

目的探讨宫腔镜电切治疗胎盘植入的可行性。方法 41例核磁共振成像（MRI）分型为Type 0、1、2的胎盘植入患者,均行宫腔镜下植入胎盘组织电切术。观察手术效果。结果手术均获得成功,40例患者一次性切除植入的胎盘组织。手术无子宫穿孔等并发症发生。手术时间10~80 min,术中出血量2~50 ml。30例患者于术后1个月后月经恢复,11例患者2个月后月经恢复。结论宫腔镜电切治疗MRI分型为Type 0、1、2的胎盘植入患者安全、可行,具有微创、可保留子宫、保留生育功能的优点。

Physiological Analysis of Two Arabidopsis thaliana Mutants in Response to CO2

[Objective] The 15urpose was to seek for the different phenotypes between wild type and Arabidopsis Mutants in response to CO2. [Method] The epidermis bioassays and seed germination test were carried out to analyze the physiological characteristics of two Arabidopsis mu- tants and their wild type. [Result] There existed distinct differences in stomata apertures, water loss and leaf temperature compared with wild type except for stomata density. In addition, seed germination test on the medium indicated that cdfl was insensitive to ABA, mannitol and NaCI, but cdsl performed contrary to cdil. [ Conclusion] There are some different physiological characteristics between wild type and mutants.

A Thin Cloud Removal Method from Remote Sensing Image for Water Body Identification

In this paper,a thin cloud removal method was put forward based on the linear relationships between the thin cloud reflectance in the channels from 0.4 μm to 1.0 μm and 1.38 μm.Channels of 0.66 μm,0.86 μm and 1.38 μm were chosen to extract the water body information under the thin cloud.Two study cases were selected to validate the thin cloud removal method.One case was applied with the Earth Observation System Moderate Resolution Imaging Spectroradiometer(EOS/MODIS) data,and the other with the Medium Resolution Spectral Imager(MERSI) and Visible and Infrared Radiometer(VIRR) data from Fengyun-3A(FY-3A).The test results showed that thin cloud removal method did not change the reflectivity of the ground surface under the clear sky.To the area contaminated by the thin cloud,the reflectance decreased to be closer to the reference reflectance under the clear sky after the thin cloud removal.The spatial distribution of the water body area could not be extracted before the thin cloud removal,while water information could be easily identified by using proper near infrared channel threshold after removing the thin cloud.The thin cloud removal method could improve the image quality and water body extraction precision effectively.

膝关节内侧盘状半月板MRI分型及损伤特点研究

目的探讨膝关节内侧盘状半月板的MRI诊断标准、分型及损伤特点。方法回顾性分析2009年11月-2015年3月行膝关节MRI检查的患者资料,筛查出内侧盘状半月板患者26例(28个患膝)进行研究,对冠状位髁间棘层面内侧半月板宽度与胫骨平台宽度之比(板面比)、矢状位半月板后角最厚层面厚度(半月板后角厚度)与矢状位"领结样"改变层数数据进行测量、分析;同时根据MRI结果将内侧盘状半月板分为完全型与不完全型,比较两种类型内侧盘状半月板的损伤率。结果 28个内侧盘状半月板中,完全型16个,不完全型12个。板面比为0.29±0.06;半月板后角厚度为(5.31±0.92)mm。另外,盘状半月板伴撕裂17个,损伤率为60.7%,其中完全型损伤率为81.2%,不完全型损伤率为33.3%,完全型内侧盘状半月板损伤率高于不完全型,差异有统计学意义(P<0.05)。结论膝关节内侧盘状半月板MRI诊断标准为矢状位连续"领结样"改变层数≥3层、板面比≥0.20、半月板后角厚度≥4.40 mm;内侧盘状半月板分为完全型和不完全型,完全型损伤率大于不完全型。

Cloud Top Height Retrieval Using Polarizing Remote Sensing Data of POLDER

A retrieval method of cloud top heights using polarizing remote sensing is proposed in this paper. Using the vector radiative transfer model in a coupled atmosphere-ocean system, the factors influencing the upwelling linear polarizing radiance at top-of-atmosphere are analyzed, which show that the upwelling linear polarizing radiance varies remarkably with the cloud top height, but has negligible sensitivity with cloud albedo and aerosol scattering above the cloud layer. Based on this property, a cloud top height retrieval algorithm using polarizing remote sensing was developed. The algorithm has been applied to the polarizing remote sensing data of Polarization and Directionality of the Earth's Reflectances-2 (POLDER-2). The retrieved cloud top height from POLDER-2 compares well with the Moderate Resolution Imaging Spectroradiometer (MODIS) operational product with a bias of 0.83 km and standard deviation of 1.56 km.

超声内镜结合窄带放大内镜下JNET分型对结直肠肿瘤性病变浸润深度评估的价值

目的探讨日本窄带成像技术专家小组(JNET)分型联合超声内镜(EUS)在结直肠肿瘤性病变浸润深度判断中的临床应用价值。方法回顾性分析2019年10月至2020年10月衡水市人民医院内镜诊疗中心发现的86例结直肠息肉样病变患者的临床资料。所有患者术前均按JNET分型对病变微血管分型,并用EUS评估其浸润深度;与内镜下黏膜切除术、黏膜下剥离术、外科手术所获组织病理结果加以对比;以病理结果为金标准,分析EUS联合JNET分型判定结肠肿瘤性病变浸润深度的可靠性,并与单用JNET分型评估进行对比,一致性分析采用Kappa检验。结果86例患者94个病灶,JNET分型1型与病理诊断增生性息肉/无蒂锯齿状息肉(SSP)的符合率为82.1%(23/28),2A型与病理诊断低级别上皮内瘤变(LGIN)的符合率84.1%(32/38),2B型与病理诊断高级别上皮肉瘤变(HGIN)/黏膜内癌(M)/黏膜下浅层浸润癌(SM-s)的符合率为65.2%(15/23),3型与病理诊断黏膜下深层浸润癌(SM-d)的符合率为61.1%(11/18)。以病理结果为准,EUS联合JNET分型判断病变浸润深度的准确度为97.06%(33/34);一致性检验结果提示,单独JNET分型与病理诊断结果一致性中等(Kappa值0.580,P<0.01),而EUS联合JNET分型与病理诊断结果一致性较高(Kappa值0.940,P<0.01)。结论JNET分型与病理诊断具有一定符合率,但部分亚型符合率仍较低,JNET分型与EUS联合在结直肠肿瘤性病变浸润深度判断中的准确度高于单用JNET分型。

Classification of breast lesions based on a dual S-shaped logistic model in dynamic contrast enhanced magnetic resonance imaging

This study proposes a novel dual S-shaped logistic model for automatically quantifying the characteristic kinetic curves of breast lesions and for distinguishing malignant from benign breast tumors on dynamic contrast enhanced (DCE) magnetic resonance (MR) images.D(,) is the diagnostic parameter derived from the logistic model.Significant differences were found in D(,) between the malignant benign groups.Fisher's Linear Discriminant analysis correctly classified more than 90% of the benign and malignant kinetic breast data using the derived diagnostic parameter (D(,)).Receiver operating characteristic curve analysis of the derived diagnostic parameter (D(,)) indicated high sensitivity and specificity to differentiate malignancy from benignancy.The dual S-shaped logistic model was effectively used to fit the kinetic curves of breast lesions in DCE-MR.Separation between benign and malignant breast lesions was achieved with sufficient accuracy by using the derived diagnostic parameter D(,) as the lesion's feature.The proposed method therefore has the potential for computer-aided diagnosis in breast tumors.

Resolution of ghost imaging with entangled photons for different types of momentum correlation

We present an analytical analysis of the spatial resolution of quantum ghost imaging implemented by entangled photons from a general, spontaneously parametric, down-conversion process. We find that the resolution is affected by both the pump beam waist and the nonlinear crystal length. Hence, we determined a method to improve the resolution for a certain imaging setup. It should be noted that the resolution is not uniquely related to the degree of entanglement of the photon pair since the resolution can be optimized for a certain degree of entanglement. For certain types of Einstein-Podolsky-Rosen(EPR) states——namely the momentum-correlated or momentum-positively correlated states——the resolution exhibits a simpler relationship with the pump beam waist and crystal length. Further, a vivid numerical simulation of ghost imaging is presented for different types of EPR states,which supports our analysis. This work discusses applicable references to the applications of quantum ghost imaging.

A Study on the Correlativity of MRI Signal Classifications with TCM Syndromes in Femoral Head Necrosis Patients

Objective:To probe into the relation between magnetic resonance imaging(MRI) signal classifications and TCM syndromes in femoral head necrosis patients,so as to provide reference for TCM diagnosis of this disease.Methods:Refering to the criteria for TCM syndrome types of necrosis of the femoral head described in "The Guiding Principles of Clinical Studies of New Chinese Drugs" and Shimizu and Mitchell's MRI signal classifications,MRI signal classifications between different TCM syndrome types were compared.Results:The Shimizu signal classification of different TCM syndrome types had statistically significant difference(P=0.04);Both T2WI+fs and Mitchell signal classifications of different TCM syndrome types had no statistical by significant differences(P=0.42 or P=0.15).Conclusion:There is a certain correlativity of TCM syndrome types of necrosis of the femoral head with T1WI signal classification of MRI.MRI signal classification may contribute to objectivity in TCM syndrome typing of this disease.

Dendrimer-based magnetic resonance imaging agents for brain cancer

Brain cancer is one of the most lethal and difficult-to-treat cancers because of its physical location and biological barriers. The mainstay of brain cancer treatment is surgical resection, which demands precise imaging for tumor localization and delineation. Thanks to advances in bioimaging, brain cancer can be detected earlier and resected more reliably. Magnetic resonance imaging（MRI） is the most common and preferred method to delineate brain cancer, and a contrast agent is often required to enhance imaging contrast.Dendrimers, a special family of synthetic macromolecules,constitute a particularly appealing platform for constructing MRI contrast agents by virtue of their well-defined three-dimensional structure, tunable nanosize and abundant surface terminals, which allow the accommodation of high payloads and numerous functionalities. Tuning the dendrimer size,branching and surface composition in conjunction with conjugation of MRI functionalities and targeting moieties can alter the relaxivity for MRI, overcome the blood-brain barrier and enhance tumor-specific targeting, hence improving the imaging quality and safety profile for precise and accurate imaging of brain tumors. This short review highlights the recent progress, opportunities and challenges in developing dendrimer-based MRI contrast agents for brain tumor imaging.