上皮样胃基质肿瘤(成平滑肌瘤)

Stout于1962年对一组具有上皮样圆形细胞的胃非上皮肿瘤命名为成平滑肌瘤,部分有恶变,1969年世界卫生组织称之为上皮样平滑肌瘤.鉴于免疫组织化学和电镜检查未能找到平滑肌现象,最好将此类肿瘤称之为上皮样胃基质肿瘤,并有良恶性之分.Mayo临床中心于1960～1986年曾收治477例胃基质肿瘤病人,其中55例为上皮样胃基质肿瘤,分析其临床和病理特点.全组55例中,男37例,女18例,平均年龄63岁(13～88岁),常见的症状有消化不良和疼痛(35%)、黑粪(9%)、扪及腹块(7%).1例出现肠梗阻,15例无症状(27%).18例在胃外尚有22个肿瘤.53%肿瘤位于胃体,33%位于胄窦,14%位于胃底、贲门部.肿瘤可向腔内或胃壁外生长,6例侵犯邻近器官.40例作了钡餐检查,26例发现异常,其中13例胃壁内肿瘤,1例有脐样外观,另1例有粘膜溃疡.5例有腔内息肉,5例有外在压迹.17例做了胃镜检查,12例有异常发现.

Light and electron microscopic observation of malignant gastric leiomyoblastoma

There were only a few cases of gastric leiomy-oblastoma reported in domestic literature,while themalignant ones were even more seldom.One ofthese was diagnosed by gastroscopic biopsy with lightand electron microscopy in our department in 1988.CASE REPORTA 57-yeat old- male worker,suffered from re-current dull pain over the upper abdomen for 2