The shortage of organ donors is a problem worldwide, with approximately 15% of adult patients with lifethreatening liver diseases dying while on the waiting list. The use of cell transplantation for liver disease is a...The shortage of organ donors is a problem worldwide, with approximately 15% of adult patients with lifethreatening liver diseases dying while on the waiting list. The use of cell transplantation for liver disease is an attempt to correct metabolic defects, or to support liver function as a bridge to liver transplantation and, as such, has raised a number of expectations. Most of the available studies briefly reported here focus on adult hepatocyte transplantation (HT), and the results are neither reproducible nor comparable, because the means of infusion, amount of injected cells and clinical variability differ among the studies. To better understand the specif ic role of HT in the management of end-stage liver disease, it is important that controlled studies, designed on the principles of evidence-based medicine, be done in order to guarantee the reproducibility of results.展开更多
This paper reports petrological and geochemical features and zircon U-Pb age of plagiogranite from the Hongliugou-Lapeiquan ophiolitic melange belt in the northern Altyn Tagh. The zircon U-Pb dating results yield a me...This paper reports petrological and geochemical features and zircon U-Pb age of plagiogranite from the Hongliugou-Lapeiquan ophiolitic melange belt in the northern Altyn Tagh. The zircon U-Pb dating results yield a mean ^238U/^206pb age of 512.1 ± 1.5 Ma, representing an emplacement time of the plagiogranites in the Middle Cambrian. The plagiogranites are interpreted to have derived from anatexis of hydrated amphibolites by ductile shearing during transports of the oceanic crust. Thus it is believed that the formation age of such type of plagiogranite was coeval to or slightly younger than the spreading of the Hongliugou-Lapeiquan limited oceanic basin. The new results from the plagiogranites suggest that an oceanic basin existed in the northern Altyn area during the Middle Cambrian.展开更多
文摘The shortage of organ donors is a problem worldwide, with approximately 15% of adult patients with lifethreatening liver diseases dying while on the waiting list. The use of cell transplantation for liver disease is an attempt to correct metabolic defects, or to support liver function as a bridge to liver transplantation and, as such, has raised a number of expectations. Most of the available studies briefly reported here focus on adult hepatocyte transplantation (HT), and the results are neither reproducible nor comparable, because the means of infusion, amount of injected cells and clinical variability differ among the studies. To better understand the specif ic role of HT in the management of end-stage liver disease, it is important that controlled studies, designed on the principles of evidence-based medicine, be done in order to guarantee the reproducibility of results.
基金financially supported by the China Geological Survey (Grant No. 1212010911025)National Natural Science Foundation of China (Grant No. 41002020)
文摘This paper reports petrological and geochemical features and zircon U-Pb age of plagiogranite from the Hongliugou-Lapeiquan ophiolitic melange belt in the northern Altyn Tagh. The zircon U-Pb dating results yield a mean ^238U/^206pb age of 512.1 ± 1.5 Ma, representing an emplacement time of the plagiogranites in the Middle Cambrian. The plagiogranites are interpreted to have derived from anatexis of hydrated amphibolites by ductile shearing during transports of the oceanic crust. Thus it is believed that the formation age of such type of plagiogranite was coeval to or slightly younger than the spreading of the Hongliugou-Lapeiquan limited oceanic basin. The new results from the plagiogranites suggest that an oceanic basin existed in the northern Altyn area during the Middle Cambrian.
