The traditional synthetic aperture radar(SAR) image recognition techniques focus on the electro magnetic (EM) scattering centers, ignoring the important role of the shadow information on the SAR image recognition....The traditional synthetic aperture radar(SAR) image recognition techniques focus on the electro magnetic (EM) scattering centers, ignoring the important role of the shadow information on the SAR image recognition. It is difficult to classify targets by the shadow information independently, because the shadow shape is dependent on the radar aspect angle, the depression angle and the resolution. Moreover, the shadow shapes of different targets are similar. When the multiple SAR images of one target from different aspects are available, the performance of the target recognition can be improved. Aimed at the problem, a multi-aspect SAR image recognition technique based on the shadow information is developed. It extracts shadow profiles from SAR images, and takes chain codes as the feature vectors of targets. Then, feature vectors on multiple aspects of the same target are combined with feature sequences, and the hidden Markov model (HMM) is applied to the feature sequences for the target recognition. The simulation result shows the effectiveness of the method.展开更多
Electrocatalysis is a process dealing with electrochemical reactions in the interconversion of chemical energy and electrical energy.Precise synthesis of catalytically active nanostructures is one of the key challenge...Electrocatalysis is a process dealing with electrochemical reactions in the interconversion of chemical energy and electrical energy.Precise synthesis of catalytically active nanostructures is one of the key challenges that hinder the practical application of many important energy‐related electrocatalytic reactions.Compared with conventional wet‐chemical,solid‐state and vapor deposition synthesis,electrochemical synthesis is a simple,fast,cost‐effective and precisely controllable method for the preparation of highly efficient catalytic materials.In this review,we summarize recent progress in the electrochemical synthesis of catalytic materials such as single atoms,spherical and shaped nanoparticles,nanosheets,nanowires,core‐shell nanostructures,layered nanomaterials,dendritic nanostructures,hierarchically porous nanostructures as well as composite nanostructures.Fundamental aspects of electrochemical synthesis and several main electrochemical synthesis methods are discussed.Structure‐performance correlations between electrochemically synthesized catalysts and their unique electrocatalytic properties are exemplified using selected examples.We offer the reader with a basic guide to the synthesis of highly efficient catalysts using electrochemical methods,and we propose some research challenges and future opportunities in this field.展开更多
Apostichopus japonicus Selenka is an ideal tonic food that is used traditionally in many Asian countries, and it contains many bioactive substances, such as antioxidant, antimicrobial, and anticancer materials. To con...Apostichopus japonicus Selenka is an ideal tonic food that is used traditionally in many Asian countries, and it contains many bioactive substances, such as antioxidant, antimicrobial, and anticancer materials. To convert waste liquid generated during production into a useful resource, extract from waste liquid was isolated by column chromatography and studied by the pyrogallol autoxidation and 1,10-phenanthroline-Fe^2+ oxidation methods. Results show that the extract scavenged about 91% of the superoxide anion radical at a concentration of 1.4 mg/mL and 24% of the hydroxyl radical at 3.3 mg/mL. Four compounds were isolated and identified from the extract: 2,4-dihydroxy-5-methyl-1,3-azine; 2,4-dihydroxy- 1,3-diazine; 3-O-β-D-quinovopranosyl-(1→2)-4-O-sodium sulfate-β-D-xylopranosyl]-holosta-9(11)-ene313,12β,17α-triol; and 24-ethyl-5α-cholesta-7-ene-3β-O-β-D-xylopyranoside. All of these compounds are known in A. japonicus, and were found in the waste liquid for the first time.展开更多
K2FeO4 powders were synthesized by the ex-situ and in-situ electrochemical methods, respectively, and characterized by infrared spectrum (IR), scanning electron microscopy (SEM), X-ray powder diffraction (XRD) a...K2FeO4 powders were synthesized by the ex-situ and in-situ electrochemical methods, respectively, and characterized by infrared spectrum (IR), scanning electron microscopy (SEM), X-ray powder diffraction (XRD) and BET. Their electrochemical performances were investigated by means of galvanostatic discharge and electrochemi-cal impedance spectroscopy (EIS). The results of physical characterization showed that the two samples have simi-lar structural features, but their surface morphologies and oriented growth of the crystals are different, which results in smaller specific surface area and lower solubility of the ex-situ electrosynthesized K2FeO4 sample. The results of discharge experiments indicated that the ex-situ electrosythesized K2FeO4 electrode has much larger discharge ca-pacity and lower electrode polarization than the in-situ electrosynthesized K2FeO4 electrode. It was found from the results of EIS that lower electrochemical polarization might be responsible for the improvement on the discharge performance of the ex-situ electrosynthesized K2FeO4 electrode.展开更多
The current study focuses on the electrolyte penetration of the graphite cathode in a NaF−KF−LiF−AlF_(3) aluminum-electrolysis system with a cryolite ratio of 1.3.It involves a comprehensive investigation of the elect...The current study focuses on the electrolyte penetration of the graphite cathode in a NaF−KF−LiF−AlF_(3) aluminum-electrolysis system with a cryolite ratio of 1.3.It involves a comprehensive investigation of the electrolyte in the cathode before and after electrolysis by X-ray diffraction and analysis of the results by semi-quantitative calculation in MAUD.The results show that KF can promote electrolyte penetration,with higher KF contents resulting in greater penetration.During electrolyte penetration,K_(2)NaAlF_(6) and solid solutions containing KF play important roles in KF-containing systems.LiF effectively prevents the electrolyte penetration,while the Na_(3)Li_(3)Al_(2)F_(12) phase plays an essential role in systems with high LiF contents.展开更多
Satellite observations provide large amount of information of clouds and precipitation and play an important role in the forecast of heavy rainfall.However,we have not fully taken advantage of satellite observations i...Satellite observations provide large amount of information of clouds and precipitation and play an important role in the forecast of heavy rainfall.However,we have not fully taken advantage of satellite observations in the data assimilation of numerical weather predictions,especially those in infrared channels. It is common to only assimilate radiances under clear-sky conditions since it is extremely difficult to simulate infrared transmittance in cloudy sky.On the basis of the Global and Regional Assimilation and Prediction Enhanced System 3-dimensional variance(GRAPES-3DVar),cloud liquid water content, ice-water content and cloud cover are employed as governing variables in the assimilation system.This scheme can improve the simulation of infrared transmittance by a fast radiative transfer model for TOVS (RTTOV)and adjust the atmospheric and cloud parameters based on infrared radiance observations.In this paper,we investigate a heavy rainfall over Guangdong province on May 26,2007,which is right after the onset of a South China Sea monsoon.In this case,channels of the Moderate Resolution Imaging Spectroradiometer(MODIS)for observing water vapor(Channel 27)and cloud top altitude(Channel 36)are selected for the assimilation.The process of heavy rainfall is simulated by the Weather Research and Forecasting(WRF)model.Our results show that the assimilated MODIS data can improve the distribution of water vapor and temperature in the first guess field and indirectly adjust the upper-level wind field.The tendency of adjustment agrees well with the satellite observations.The assimilation scheme has positive impacts on the short-range forecasting of rainstorm.展开更多
Study of electrochemical behavior of chromium (molybdenum, tungsten) and silicon containing melts allowed defining conditions for synthesis of silicides of chromium, molybdenum and tungsten in the form of fine powde...Study of electrochemical behavior of chromium (molybdenum, tungsten) and silicon containing melts allowed defining conditions for synthesis of silicides of chromium, molybdenum and tungsten in the form of fine powders by electrolysis of halide-oxide melts. Sequence of stages of electrosynthesis of silicides of molybdenum and tungsten was found as follows: deposition of more electroposifve metal (molybdenum or tungsten), deposition of the second component (silicon) on the surface of metal deposited previously, and reaction diffusion of silicon into the deep of the metal-salt "pear" with the formation of silicide phases of different compositions up to the higher silicides. In contrast, during the electrodeposition of chromium silicides, one of the components (chromium) is deposited not in elemental form, but in oxide form, and the other (silicon) acts as a reducing agent for this oxide to form binary compounds. Duration of the synthesis first stage (deposition of refractory metal or of its oxide) depends on the refractory metal compound content in the system and on the cathode current density. Synthesis of silicides is possible due to retention of powders of molybdenum (tungsten) or chromium oxide at the cathode without scaling. Optimal values of concentrations ratio, current density, temperature, and duration of electrosynthesis were found. Phase composition of products were obtained, as well as their chemical and thermal stability, were studied.展开更多
Well - defined diblock copolymers Of styrene (St ) and ethylene oxide (EO )have been prepared by sequential living anionic polymerization of the twocomonomers in THF. Diphenyl methyl potassium has been used as initiat...Well - defined diblock copolymers Of styrene (St ) and ethylene oxide (EO )have been prepared by sequential living anionic polymerization of the twocomonomers in THF. Diphenyl methyl potassium has been used as initiator. Theblock copolymers were characterized in detail by methods Of size exclusion chromatography (SEC ) , 1H - Nab, FT - IR, dynamic mechanical analysis(Daal ) and WAXD.展开更多
The surface modification of the anionic polyurethane(APU)film was carried out by immersing it in silk fibroin peptide(SFP)solution for 12 h and then treating with low temperature plasma glow discharge.The physical pro...The surface modification of the anionic polyurethane(APU)film was carried out by immersing it in silk fibroin peptide(SFP)solution for 12 h and then treating with low temperature plasma glow discharge.The physical properties and moisture permeability of modified films were examined.The results showed that SFP-modified APU films had better moisture permeability than oleophilic polyurethane,as well as modified APU films kept good flexibility.Modified APU films could overcome rigid and brittle weaks of silk fibroin films.The morphology of SFP on the APU film was corpuscular aggregations.The water-contact angle measurement indicated that the change of hydrophilicity and the element chemical analysis suggested that the SFP-modified film surface was enriched with nitrogen atoms.The biocompatibility of APU films may be improved due to the change of surface components.Cell viability and proliferation of rat embryo dermal fibroblasts seeded on control films,APU films and SFP-modified APU films were evaluated by MTT assay and viable cell counts,respectively.The results indicated that the APU film modified by SFP protein showed the proliferation of fibroblasts on the film,and that the compound interface had good stability in the air.Results also showed that presoaking treatment for APU films was effective to accomplish the goal of surface modification.展开更多
Objective: Radiation therapy is an important component of the multidisciplinary management of esophageal carcinoma. Three-dimensional conformal radiation therapy requires the precise definition of the target volume. ...Objective: Radiation therapy is an important component of the multidisciplinary management of esophageal carcinoma. Three-dimensional conformal radiation therapy requires the precise definition of the target volume. We aimed to compare the treatment results and radiation toxicities between three-dimensional conformal radiotherapy (3D-CRT) and conventional radiotherapy (CR) for patients with cervical and thoracic esophageal carcinoma. Methods: From June 2004 to December 2006, a random study was performed on 106 patients treated with 3D-CRT or CR, 53 patients in each group. The patients in CR group received conventional radiotherapy in 2.0 Gy/f, 5 f/week and total dose was 66-70 Gy in 6.5 or 7 weeks. The patients in 3D-CRT group were treated by 3D-CRT in 2.0 Gy/f, 5 f/week and total dose was 64-70 Gy in 6 weeks. The local control rates, survival rates and radiation toxicities for the two groups were investigated. Results: The 1-year and 3-year local control rates were 83.0% and 60.4% in 3D-CRT group and 64.2% (x^2 = 4.853, P = 0.028) and 32.1% (x^2 = 9.812, P = 0.002) in CR group. The 1-year and 3-year survival rates were 73.6% and 50.9% in 3D-CRT group and 54.7% (x^2 = 4.102, P = 0.043) and 32.1% (x^2 = 3.886, P = 0.049) in CR group. Between the two groups, there was no significant difference in radiation toxicities. Conclusien: The 1-year and 3-year local control rates and survival rates of patients with esophageal carcinoma treated by 3D-CRT is superior to CR. However, longer-term results and radiation toxicity need further study which involves more patients and prolonged follow-up.展开更多
Amine-functionalized mesoporous silica was prepared by using lauric acid and N-stearoyl-l-glutamic acid as structure directing agents via the S-N+-I- mechanism and applied to CO2 adsorption at room temperature. With ...Amine-functionalized mesoporous silica was prepared by using lauric acid and N-stearoyl-l-glutamic acid as structure directing agents via the S-N+-I- mechanism and applied to CO2 adsorption at room temperature. With γ-aminopropyltriethoxysilane as co-structure directing agent and due to the direct electrostatic interaction with anionic surfactant, most of the amino groups were uniformly distributed at the inner surface of pores and the per- formance was stable. The amine-functionalized mesoporous silica was characterized by Fourier transform infrared spectrometer, X-ray diffraction, nitrogen physisorption and thermogravimetric analysis. The CO2 adsorption capacity was measured by digital recording balance. At the room temperature and under the atmospheric pressure, the adsorption capacity of LAA-AMS-0.2 for CO2 and N2 is 1.40 mmol·g-1 and 0.03 mmol·g-1, respectively, indicating high separation coefficient of CO2/N2.展开更多
Three 3,3'-di(4-substituted-phenyl)-1,1'-isophthaloylbis(thiourea) compounds were designed as novel neutral anion receptors, and synthesized by simple steps in good yields. The single crystal structure of recept...Three 3,3'-di(4-substituted-phenyl)-1,1'-isophthaloylbis(thiourea) compounds were designed as novel neutral anion receptors, and synthesized by simple steps in good yields. The single crystal structure of receptor 1 shows that a solvent molecule was captured by the host molecule through intermolecular hydrogen bonding. Moreover, it was self-assembled as a supramolecular system for the presence of abundant inter- and intramolecular hydrogen bonding and π-π interactions between phenyl groups. Their application as anion receptors has been examined by UV-Vis and ^1H NMR spectroscopy, showing that they had a higher selectivity for fluoride than other halides. The host and guest formed a 1 : 1 stoichiometry complex through hydrogen bonding interactions in the first step, then following a process of deprotonation in presence of an excess of F^- in the solvent of DMF.展开更多
Peptide thioester preparation via intramolecular O-to-S acyl transfer is a recently developed method for protein chemical synthesis through Fmoc chemistry. Theoretical calculations have been carried out to study the m...Peptide thioester preparation via intramolecular O-to-S acyl transfer is a recently developed method for protein chemical synthesis through Fmoc chemistry. Theoretical calculations have been carried out to study the mechanism for the formation of thioesters via O-to-S acyl transfer. It is found that the O-to-S acyl transfer occurs via an anionic stepwise mechanism in which the cleavage of the C-O bond is the rate-limiting step. The side reaction of hydrolysis also proceeds through an anionic stepwise process, and its rate-limiting step is the attack of the hydroxide ion on the carbonyl carbon. Increase of the chain length between the ester O atom and the S atom can increase the energy barrier of the O-to-S acyl transfer. On the other hand, substituents at the α-position of the ester can reduce the energy barrier.展开更多
Background Most incidental gastric polyps identified during upper endoscopy are considered low-risk.However,current guidelines recommend sampling all gastric polyps for histopathologic analysis.We aimed to devise a si...Background Most incidental gastric polyps identified during upper endoscopy are considered low-risk.However,current guidelines recommend sampling all gastric polyps for histopathologic analysis.We aimed to devise a simple narrow-band imaging(NBI)classification to reduce the need for routine biopsies of low-risk gastric polyps.Methods Pairs of NBI and white-light images were collected from 73 gastric polyps for which concurrent histopathologic diagnosis was available.A diagnostic accuracy cohort study was performed.Two blinded endoscopists independently analysed NBI features of each polyp for color,vessel pattern,surface pattern,and any combinations thereof to develop a classification scheme to differentiate low-risk polyps(fundic-gland or hyperplastic)from high-risk polyps(adenomatous or adenocarcinoma)and fundic-gland polyps(FGPs)from non-FGPs.Results An isolated lacy vessel pattern and a homogenous absence of surface pattern successfully differentiated low-risk from high-risk gastric polyps.Combining both descriptors into a single algorithm resulted in a negative predictive value(NPV)of 100%[95%confidence interval(CI):100%–100%],positive predictive value(PPV)of 13.7%(95%CI:2.6–24.8),sensitivity of 100%(95%CI:100%–100%),and specificity of 53.7%(95%CI:45.3%–62.0%)for high-risk polyps.This would reduce the number of polyps requiring biopsy by 50%,while still capturing all high-risk polyps.Regarding FGPs,using a rule not to biopsy polyps with isolated lacy vessels resulted in a 94.9%NPV(95%CI:89.2%–100%),63.2%PPV(95%CI:47.2%–79.2%),94.8%sensitivity(95%CI:89.5%–100%),and 63.6%specificity(95%CI:51.3%–76.0%)for non-FGPs.Conclusion In this derivation cohort study,NBI is helpful for differentiating between high-risk and low-risk gastric polyps,thereby reducing the need for routine sampling of low-risk polyps.These results need to be validated in a separate test population.展开更多
文摘The traditional synthetic aperture radar(SAR) image recognition techniques focus on the electro magnetic (EM) scattering centers, ignoring the important role of the shadow information on the SAR image recognition. It is difficult to classify targets by the shadow information independently, because the shadow shape is dependent on the radar aspect angle, the depression angle and the resolution. Moreover, the shadow shapes of different targets are similar. When the multiple SAR images of one target from different aspects are available, the performance of the target recognition can be improved. Aimed at the problem, a multi-aspect SAR image recognition technique based on the shadow information is developed. It extracts shadow profiles from SAR images, and takes chain codes as the feature vectors of targets. Then, feature vectors on multiple aspects of the same target are combined with feature sequences, and the hidden Markov model (HMM) is applied to the feature sequences for the target recognition. The simulation result shows the effectiveness of the method.
文摘Electrocatalysis is a process dealing with electrochemical reactions in the interconversion of chemical energy and electrical energy.Precise synthesis of catalytically active nanostructures is one of the key challenges that hinder the practical application of many important energy‐related electrocatalytic reactions.Compared with conventional wet‐chemical,solid‐state and vapor deposition synthesis,electrochemical synthesis is a simple,fast,cost‐effective and precisely controllable method for the preparation of highly efficient catalytic materials.In this review,we summarize recent progress in the electrochemical synthesis of catalytic materials such as single atoms,spherical and shaped nanoparticles,nanosheets,nanowires,core‐shell nanostructures,layered nanomaterials,dendritic nanostructures,hierarchically porous nanostructures as well as composite nanostructures.Fundamental aspects of electrochemical synthesis and several main electrochemical synthesis methods are discussed.Structure‐performance correlations between electrochemically synthesized catalysts and their unique electrocatalytic properties are exemplified using selected examples.We offer the reader with a basic guide to the synthesis of highly efficient catalysts using electrochemical methods,and we propose some research challenges and future opportunities in this field.
基金Supported by the National Special Research Fund for Non-Profit Sector(Ocean)(No.201205025-5)
文摘Apostichopus japonicus Selenka is an ideal tonic food that is used traditionally in many Asian countries, and it contains many bioactive substances, such as antioxidant, antimicrobial, and anticancer materials. To convert waste liquid generated during production into a useful resource, extract from waste liquid was isolated by column chromatography and studied by the pyrogallol autoxidation and 1,10-phenanthroline-Fe^2+ oxidation methods. Results show that the extract scavenged about 91% of the superoxide anion radical at a concentration of 1.4 mg/mL and 24% of the hydroxyl radical at 3.3 mg/mL. Four compounds were isolated and identified from the extract: 2,4-dihydroxy-5-methyl-1,3-azine; 2,4-dihydroxy- 1,3-diazine; 3-O-β-D-quinovopranosyl-(1→2)-4-O-sodium sulfate-β-D-xylopranosyl]-holosta-9(11)-ene313,12β,17α-triol; and 24-ethyl-5α-cholesta-7-ene-3β-O-β-D-xylopyranoside. All of these compounds are known in A. japonicus, and were found in the waste liquid for the first time.
基金Supported by the National Natural Science Foundation of China (No.50172041)partly by the Chinese State Key Labora-tory for Corrosion and Protection.
文摘K2FeO4 powders were synthesized by the ex-situ and in-situ electrochemical methods, respectively, and characterized by infrared spectrum (IR), scanning electron microscopy (SEM), X-ray powder diffraction (XRD) and BET. Their electrochemical performances were investigated by means of galvanostatic discharge and electrochemi-cal impedance spectroscopy (EIS). The results of physical characterization showed that the two samples have simi-lar structural features, but their surface morphologies and oriented growth of the crystals are different, which results in smaller specific surface area and lower solubility of the ex-situ electrosynthesized K2FeO4 sample. The results of discharge experiments indicated that the ex-situ electrosythesized K2FeO4 electrode has much larger discharge ca-pacity and lower electrode polarization than the in-situ electrosynthesized K2FeO4 electrode. It was found from the results of EIS that lower electrochemical polarization might be responsible for the improvement on the discharge performance of the ex-situ electrosynthesized K2FeO4 electrode.
基金financial supports from the National Natural Science Foundation of China (Nos.51774080,22078056)the National Key R&D Program of China (No.2018YFC1901905)。
文摘The current study focuses on the electrolyte penetration of the graphite cathode in a NaF−KF−LiF−AlF_(3) aluminum-electrolysis system with a cryolite ratio of 1.3.It involves a comprehensive investigation of the electrolyte in the cathode before and after electrolysis by X-ray diffraction and analysis of the results by semi-quantitative calculation in MAUD.The results show that KF can promote electrolyte penetration,with higher KF contents resulting in greater penetration.During electrolyte penetration,K_(2)NaAlF_(6) and solid solutions containing KF play important roles in KF-containing systems.LiF effectively prevents the electrolyte penetration,while the Na_(3)Li_(3)Al_(2)F_(12) phase plays an essential role in systems with high LiF contents.
基金Natural Foundamental Research and Development Project"973"Program(2009CB421500)Natural Science Foundation of China(7035011)
文摘Satellite observations provide large amount of information of clouds and precipitation and play an important role in the forecast of heavy rainfall.However,we have not fully taken advantage of satellite observations in the data assimilation of numerical weather predictions,especially those in infrared channels. It is common to only assimilate radiances under clear-sky conditions since it is extremely difficult to simulate infrared transmittance in cloudy sky.On the basis of the Global and Regional Assimilation and Prediction Enhanced System 3-dimensional variance(GRAPES-3DVar),cloud liquid water content, ice-water content and cloud cover are employed as governing variables in the assimilation system.This scheme can improve the simulation of infrared transmittance by a fast radiative transfer model for TOVS (RTTOV)and adjust the atmospheric and cloud parameters based on infrared radiance observations.In this paper,we investigate a heavy rainfall over Guangdong province on May 26,2007,which is right after the onset of a South China Sea monsoon.In this case,channels of the Moderate Resolution Imaging Spectroradiometer(MODIS)for observing water vapor(Channel 27)and cloud top altitude(Channel 36)are selected for the assimilation.The process of heavy rainfall is simulated by the Weather Research and Forecasting(WRF)model.Our results show that the assimilated MODIS data can improve the distribution of water vapor and temperature in the first guess field and indirectly adjust the upper-level wind field.The tendency of adjustment agrees well with the satellite observations.The assimilation scheme has positive impacts on the short-range forecasting of rainstorm.
文摘Study of electrochemical behavior of chromium (molybdenum, tungsten) and silicon containing melts allowed defining conditions for synthesis of silicides of chromium, molybdenum and tungsten in the form of fine powders by electrolysis of halide-oxide melts. Sequence of stages of electrosynthesis of silicides of molybdenum and tungsten was found as follows: deposition of more electroposifve metal (molybdenum or tungsten), deposition of the second component (silicon) on the surface of metal deposited previously, and reaction diffusion of silicon into the deep of the metal-salt "pear" with the formation of silicide phases of different compositions up to the higher silicides. In contrast, during the electrodeposition of chromium silicides, one of the components (chromium) is deposited not in elemental form, but in oxide form, and the other (silicon) acts as a reducing agent for this oxide to form binary compounds. Duration of the synthesis first stage (deposition of refractory metal or of its oxide) depends on the refractory metal compound content in the system and on the cathode current density. Synthesis of silicides is possible due to retention of powders of molybdenum (tungsten) or chromium oxide at the cathode without scaling. Optimal values of concentrations ratio, current density, temperature, and duration of electrosynthesis were found. Phase composition of products were obtained, as well as their chemical and thermal stability, were studied.
文摘Well - defined diblock copolymers Of styrene (St ) and ethylene oxide (EO )have been prepared by sequential living anionic polymerization of the twocomonomers in THF. Diphenyl methyl potassium has been used as initiator. Theblock copolymers were characterized in detail by methods Of size exclusion chromatography (SEC ) , 1H - Nab, FT - IR, dynamic mechanical analysis(Daal ) and WAXD.
基金Supported by the National Basic Research 973 Programof China(No.2005CB623906)
文摘The surface modification of the anionic polyurethane(APU)film was carried out by immersing it in silk fibroin peptide(SFP)solution for 12 h and then treating with low temperature plasma glow discharge.The physical properties and moisture permeability of modified films were examined.The results showed that SFP-modified APU films had better moisture permeability than oleophilic polyurethane,as well as modified APU films kept good flexibility.Modified APU films could overcome rigid and brittle weaks of silk fibroin films.The morphology of SFP on the APU film was corpuscular aggregations.The water-contact angle measurement indicated that the change of hydrophilicity and the element chemical analysis suggested that the SFP-modified film surface was enriched with nitrogen atoms.The biocompatibility of APU films may be improved due to the change of surface components.Cell viability and proliferation of rat embryo dermal fibroblasts seeded on control films,APU films and SFP-modified APU films were evaluated by MTT assay and viable cell counts,respectively.The results indicated that the APU film modified by SFP protein showed the proliferation of fibroblasts on the film,and that the compound interface had good stability in the air.Results also showed that presoaking treatment for APU films was effective to accomplish the goal of surface modification.
文摘Objective: Radiation therapy is an important component of the multidisciplinary management of esophageal carcinoma. Three-dimensional conformal radiation therapy requires the precise definition of the target volume. We aimed to compare the treatment results and radiation toxicities between three-dimensional conformal radiotherapy (3D-CRT) and conventional radiotherapy (CR) for patients with cervical and thoracic esophageal carcinoma. Methods: From June 2004 to December 2006, a random study was performed on 106 patients treated with 3D-CRT or CR, 53 patients in each group. The patients in CR group received conventional radiotherapy in 2.0 Gy/f, 5 f/week and total dose was 66-70 Gy in 6.5 or 7 weeks. The patients in 3D-CRT group were treated by 3D-CRT in 2.0 Gy/f, 5 f/week and total dose was 64-70 Gy in 6 weeks. The local control rates, survival rates and radiation toxicities for the two groups were investigated. Results: The 1-year and 3-year local control rates were 83.0% and 60.4% in 3D-CRT group and 64.2% (x^2 = 4.853, P = 0.028) and 32.1% (x^2 = 9.812, P = 0.002) in CR group. The 1-year and 3-year survival rates were 73.6% and 50.9% in 3D-CRT group and 54.7% (x^2 = 4.102, P = 0.043) and 32.1% (x^2 = 3.886, P = 0.049) in CR group. Between the two groups, there was no significant difference in radiation toxicities. Conclusien: The 1-year and 3-year local control rates and survival rates of patients with esophageal carcinoma treated by 3D-CRT is superior to CR. However, longer-term results and radiation toxicity need further study which involves more patients and prolonged follow-up.
基金Supported by Tianjin Hi-tech Support Program Key Projects, China (2009F3-0005)
文摘Amine-functionalized mesoporous silica was prepared by using lauric acid and N-stearoyl-l-glutamic acid as structure directing agents via the S-N+-I- mechanism and applied to CO2 adsorption at room temperature. With γ-aminopropyltriethoxysilane as co-structure directing agent and due to the direct electrostatic interaction with anionic surfactant, most of the amino groups were uniformly distributed at the inner surface of pores and the per- formance was stable. The amine-functionalized mesoporous silica was characterized by Fourier transform infrared spectrometer, X-ray diffraction, nitrogen physisorption and thermogravimetric analysis. The CO2 adsorption capacity was measured by digital recording balance. At the room temperature and under the atmospheric pressure, the adsorption capacity of LAA-AMS-0.2 for CO2 and N2 is 1.40 mmol·g-1 and 0.03 mmol·g-1, respectively, indicating high separation coefficient of CO2/N2.
基金Project supported by the National Natural Science Foundation of China (No. 20671077), the Key Scientific and Technical Research Project of Ministry of Education of China (No. 205161), the Youth Foundation of Gansu Province (No. 3YS051-A25-010), the Natural Science Foundation of Gansu Province in China (No. 3ZS061-A25-027) and the Scientific Research Fund of Education Department of Gansu Province (No. 0601-24).
文摘Three 3,3'-di(4-substituted-phenyl)-1,1'-isophthaloylbis(thiourea) compounds were designed as novel neutral anion receptors, and synthesized by simple steps in good yields. The single crystal structure of receptor 1 shows that a solvent molecule was captured by the host molecule through intermolecular hydrogen bonding. Moreover, it was self-assembled as a supramolecular system for the presence of abundant inter- and intramolecular hydrogen bonding and π-π interactions between phenyl groups. Their application as anion receptors has been examined by UV-Vis and ^1H NMR spectroscopy, showing that they had a higher selectivity for fluoride than other halides. The host and guest formed a 1 : 1 stoichiometry complex through hydrogen bonding interactions in the first step, then following a process of deprotonation in presence of an excess of F^- in the solvent of DMF.
基金support to the study by the National Natural Science Foundation of China (20932006)
文摘Peptide thioester preparation via intramolecular O-to-S acyl transfer is a recently developed method for protein chemical synthesis through Fmoc chemistry. Theoretical calculations have been carried out to study the mechanism for the formation of thioesters via O-to-S acyl transfer. It is found that the O-to-S acyl transfer occurs via an anionic stepwise mechanism in which the cleavage of the C-O bond is the rate-limiting step. The side reaction of hydrolysis also proceeds through an anionic stepwise process, and its rate-limiting step is the attack of the hydroxide ion on the carbonyl carbon. Increase of the chain length between the ester O atom and the S atom can increase the energy barrier of the O-to-S acyl transfer. On the other hand, substituents at the α-position of the ester can reduce the energy barrier.
文摘Background Most incidental gastric polyps identified during upper endoscopy are considered low-risk.However,current guidelines recommend sampling all gastric polyps for histopathologic analysis.We aimed to devise a simple narrow-band imaging(NBI)classification to reduce the need for routine biopsies of low-risk gastric polyps.Methods Pairs of NBI and white-light images were collected from 73 gastric polyps for which concurrent histopathologic diagnosis was available.A diagnostic accuracy cohort study was performed.Two blinded endoscopists independently analysed NBI features of each polyp for color,vessel pattern,surface pattern,and any combinations thereof to develop a classification scheme to differentiate low-risk polyps(fundic-gland or hyperplastic)from high-risk polyps(adenomatous or adenocarcinoma)and fundic-gland polyps(FGPs)from non-FGPs.Results An isolated lacy vessel pattern and a homogenous absence of surface pattern successfully differentiated low-risk from high-risk gastric polyps.Combining both descriptors into a single algorithm resulted in a negative predictive value(NPV)of 100%[95%confidence interval(CI):100%–100%],positive predictive value(PPV)of 13.7%(95%CI:2.6–24.8),sensitivity of 100%(95%CI:100%–100%),and specificity of 53.7%(95%CI:45.3%–62.0%)for high-risk polyps.This would reduce the number of polyps requiring biopsy by 50%,while still capturing all high-risk polyps.Regarding FGPs,using a rule not to biopsy polyps with isolated lacy vessels resulted in a 94.9%NPV(95%CI:89.2%–100%),63.2%PPV(95%CI:47.2%–79.2%),94.8%sensitivity(95%CI:89.5%–100%),and 63.6%specificity(95%CI:51.3%–76.0%)for non-FGPs.Conclusion In this derivation cohort study,NBI is helpful for differentiating between high-risk and low-risk gastric polyps,thereby reducing the need for routine sampling of low-risk polyps.These results need to be validated in a separate test population.