目的应用超声生物显微镜(UBM)观察孔源性视网膜脱离(RRD)患者巩膜扣带术后房角开放距离(AOD)的变化与眼压升高之间的关系。方法选取56例行巩膜扣带术的RRD患者,根据术后1 d眼压情况分为眼压升高组[眼压升高≥8 mm Hg(1 mm Hg=0.133 k P...目的应用超声生物显微镜(UBM)观察孔源性视网膜脱离(RRD)患者巩膜扣带术后房角开放距离(AOD)的变化与眼压升高之间的关系。方法选取56例行巩膜扣带术的RRD患者,根据术后1 d眼压情况分为眼压升高组[眼压升高≥8 mm Hg(1 mm Hg=0.133 k Pa)]和眼压稳定组(眼压升高<8 mm Hg),比较术前、术后两组间AOD的变化。结果 1与术前比较,两组术后眼压均升高(P<0.01),其中眼压升高组术后1 d升高最明显,随后逐渐下降,1周后眼压升高<8 mm Hg;两组术前眼压比较差异无统计学意义,眼压升高组术后3个月内眼压升高均高于眼压稳定组(均P<0.01),术后6个月差异无统计学意义。2与术前比较,两组术后1 d AOD减小最明显,随后逐渐恢复,术后1个月内均减小(均P<0.01),3个月后差异无统计学意义;眼压升高组术前、术后AOD均小于眼压稳定组(均P<0.01)。3以术前AOD预测术后眼压升高的最佳截断值为0.41 mm,敏感性92.30%,特异性86.00%,ROC曲线下面积0.829。结论眼压升高主要发生在巩膜扣带术后早期,影响是暂时的、可逆的;眼压升高与房角窄密切相关,术前房角窄患者术后更容易出现眼压升高。展开更多
Objective: To assess the accuracy of classification of narrow anterior chamber (AC) angles using quantitative imaging by optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM). Design: Observational com...Objective: To assess the accuracy of classification of narrow anterior chamber (AC) angles using quantitative imaging by optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM). Design: Observational comparative study. Methods: A high-speed (4000 axial scans/s) anterior segment OCT prototype was developed using a 1.3- μ m light source. Seventeen normal subjects (17 eyes) and 7 subjects (14 eyes)-with narrow angle glaucoma were enrolled. All subjects underwentg onioscopy, OCT, and UBM. Quantitative AC angle parameters (angle opening distance, angle recess area, and the trabecular-iris space area [a new parameter we have defined])-were measured from OCT and UBM images using proprietary processing software. Main Outcome Measures: Specificity and sensitivity in identifying narrow angles with image-derived AC angle parameters. Results: Eight of 31 eyes were classified as having narrow angles (Shaffer grade ≤ 1 in all quadrants). The AC angle parameters measured by both OCT and UBM had similar mean values, reproducibility, and sensitivity specificity profiles. Both OCT and UBM showed excellent performance in identifying eyes with narrow angles. Areas under the receiver operating characteristic curves for these parameters were all in the range of 0.96 to 0.98. Conclusions: Optical coherence tomography was similar to UBM in quantitative AC angle measurement and detection of narrow angles. In addition, it was easier to use and did not require contact with the eye. Optical coherence tomography is a promising method for screening individuals at risk for narrow angle glaucoma.展开更多
文摘目的应用超声生物显微镜(UBM)观察孔源性视网膜脱离(RRD)患者巩膜扣带术后房角开放距离(AOD)的变化与眼压升高之间的关系。方法选取56例行巩膜扣带术的RRD患者,根据术后1 d眼压情况分为眼压升高组[眼压升高≥8 mm Hg(1 mm Hg=0.133 k Pa)]和眼压稳定组(眼压升高<8 mm Hg),比较术前、术后两组间AOD的变化。结果 1与术前比较,两组术后眼压均升高(P<0.01),其中眼压升高组术后1 d升高最明显,随后逐渐下降,1周后眼压升高<8 mm Hg;两组术前眼压比较差异无统计学意义,眼压升高组术后3个月内眼压升高均高于眼压稳定组(均P<0.01),术后6个月差异无统计学意义。2与术前比较,两组术后1 d AOD减小最明显,随后逐渐恢复,术后1个月内均减小(均P<0.01),3个月后差异无统计学意义;眼压升高组术前、术后AOD均小于眼压稳定组(均P<0.01)。3以术前AOD预测术后眼压升高的最佳截断值为0.41 mm,敏感性92.30%,特异性86.00%,ROC曲线下面积0.829。结论眼压升高主要发生在巩膜扣带术后早期,影响是暂时的、可逆的;眼压升高与房角窄密切相关,术前房角窄患者术后更容易出现眼压升高。
文摘Objective: To assess the accuracy of classification of narrow anterior chamber (AC) angles using quantitative imaging by optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM). Design: Observational comparative study. Methods: A high-speed (4000 axial scans/s) anterior segment OCT prototype was developed using a 1.3- μ m light source. Seventeen normal subjects (17 eyes) and 7 subjects (14 eyes)-with narrow angle glaucoma were enrolled. All subjects underwentg onioscopy, OCT, and UBM. Quantitative AC angle parameters (angle opening distance, angle recess area, and the trabecular-iris space area [a new parameter we have defined])-were measured from OCT and UBM images using proprietary processing software. Main Outcome Measures: Specificity and sensitivity in identifying narrow angles with image-derived AC angle parameters. Results: Eight of 31 eyes were classified as having narrow angles (Shaffer grade ≤ 1 in all quadrants). The AC angle parameters measured by both OCT and UBM had similar mean values, reproducibility, and sensitivity specificity profiles. Both OCT and UBM showed excellent performance in identifying eyes with narrow angles. Areas under the receiver operating characteristic curves for these parameters were all in the range of 0.96 to 0.98. Conclusions: Optical coherence tomography was similar to UBM in quantitative AC angle measurement and detection of narrow angles. In addition, it was easier to use and did not require contact with the eye. Optical coherence tomography is a promising method for screening individuals at risk for narrow angle glaucoma.
