Unsymmetrically substituted ureas are widely used in agriculture, medicine and biology. A series of chiral N,N’unsymmetrically disubstituted ureas have been designed and synthesized by the method of onepot. Inste...Unsymmetrically substituted ureas are widely used in agriculture, medicine and biology. A series of chiral N,N’unsymmetrically disubstituted ureas have been designed and synthesized by the method of onepot. Instead of using toxic phosgene, a convent and safe reagent, the commercial triphosgene, was employed in the preparation.展开更多
文摘Unsymmetrically substituted ureas are widely used in agriculture, medicine and biology. A series of chiral N,N’unsymmetrically disubstituted ureas have been designed and synthesized by the method of onepot. Instead of using toxic phosgene, a convent and safe reagent, the commercial triphosgene, was employed in the preparation.
